Clinical trials: Amino Acids, Essential
Sarcopenia
Milk and Milk-produce to Counteract the Loss of Muscle Mass and Function in Exercising Older Adults.
This project evaluates the use of different types of proteins from various food sources after an exercise session, on muscle mass and physical capacity in aged sarcopenic men (who have low muscle mass).
- Trial name
- PRO (NCT01883674)
- Testing
- Resistance training
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Nutritional Stunting, Growth Failure
Nutritional Stimulation of Growth in Children With Short Stature
Short stature is a frequent reason for referral to a pediatric endocrinology clinic. Short stature is especially prevalent among those with failure to thrive (whose weight is significantly below the average weight of his/her…
- Trial name
- NCT04226586
- Testing
- Essential Amino Acid (EAA) group
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Non-small Cell Lung Cancer
Effects of Essential Amino Acid Intake on Net Protein Synthesis in Weight-losing Non-small Cell Lung Cancer Patients
Weight loss commonly occurs in lung cancer patients, negatively influencing their quality of life, treatment response and survival.
- Trial name
- NCT01172314
- Testing
- EAA+LEU vs total AA, Total AA vs EAA+LEU
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Cirrhosis, Liver
Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis
Loss of skeletal muscle mass or sarcopenia is the most common and potentially reversible complication in cirrhosis that increases morbidity and mortality before, during and after liver transplantation.
- Trial name
- NCT03208868
- Testing
- Leucine enriched essential amino acid (EEA/LEU), Balanced amino acid supplement (BAA)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Major Depressive Disorder (MDD)
Role of Kynurenine Pathway and Its Metabolites in Depressive Disorders, Major Depressive Disorder is Suspected to Have the Greatest Burden by 2030,Kynurenine Pathway is Major Route Through Which the Essential Amino Acid Tryptophan is Metabolised and Activated in Time of Stress and Immune Activation.
This is a case control study including simple random cases of 90 persons, 45 of them have depressive disorders and the other 45 are healthy individuals,age group between 18-60 years old, cases will be recruited from outpatient…
- Trial name
- NCT07771517
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cardiovascular Risk Factor, Obesity
Essential Amino Acids and High Intensity Interval Training
Purpose: The primary purpose is to determine the combined effects of essential amino acids (EAA) supplementation and high intensity interval training (HIIT) on body composition, muscle characteristics, and muscle architecture in…
- Trial name
- NCT04080102
- Testing
- High Intensity Interval Training, Essential Amino Acid, High intensity interval training and essential amino acid supplement
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Weight Loss
Nutritional Stimulation of Muscle Protein Synthesis and Metabolic Rate After Bariatric Surgery
Bariatric surgery is an effective treatment for severe obesity but results in loss of muscle mass. The investigators will test the hypothesis that consumption of an Essential Amino Acid-based nutritional formulation will maintain…
- Trial name
- NCT04751916
- Testing
- Essential Amino Acid Protein Supplement, Beneprotein®
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Healthy Adult Males
Non- Essential Amino Acid Requirements and Metabolism in Humans
Protein is a major structural component of all cells in the body. The nutritional importance of protein is because of their amino acids.
- Trial name
- NCT02009917
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cystic Fibrosis
Leucine-enriched Essential Amino Acid Intake to Optimize Protein Anabolism in Children With Cystic Fibrosis
Malnutrition, including muscle wasting commonly occurs in children with cystic fibrosis (CF), negatively influencing their quality of life and survival.
- Trial name
- NCT01172301
- Testing
- Essential amino acid intake + Leucine vs total AA supplement
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Texas A&M University
Postoperative Recovery, Total Knee Arthroplasty
Nutrition and Swelling
This study is looking at whether taking a nutritional supplement before and after knee replacement surgery affects normal recovery.
- Trial name
- NCT07899762
- Testing
- Xcelerated Recovery Nutritional Supplement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Refractory Epilepsy, Drug Resistant Epilepsy
Leucine Enriched Essential Amino Acid Powder as an Add-on to a Classic Ketogenic Diet in Refractory Epilepsy
The main purpose of this study is to evaluate the safety and tolerability of a Leucine-Enriched Essential Amino Acid (LEAA) Powder as an add-on to a classic ketogenic diet (KD) in pediatric and adult patients with refractory…
- Trial name
- NCT06387186
- Testing
- Leucine-Enriched Essential Amino Acid powder
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Elizabeth Anne Thiele
Lumbar Spinal Stenosis
Targeted Nutritional Supplement After Lumbar Spine Surgery: A Randomized, Placebo-Controlled, Double-Blind Trial
The goal of this clinical trial is to prospectively evaluate the effects of essential amino acid (EAA) supplementation on the volume and structure of the muscles surrounding the spine (paraspinal musculature).
- Trial name
- NCT06579391
- Testing
- Essential amino acids, Alanine
- Where
- United States
- Sponsor
- University of California, Irvine
Old Age (Focus; Not a Recognized Condition)
Dysfunction of Nutritive Blood Flow as a Determinant of Anabolic Resistance With Age; the Role of Amino Acids in Modulating Muscle Metabolism
The investigators plan to measure changes in muscle protein metabolism in response to feeding, comparing between a single large essential amino acid (EAA) feed (the normal building blocks of protein) and the provision of the same…
- Trial name
- Ajinomoto1A (NCT01735539)
- Testing
- 15g EAA bolus, 4 x 3.75g Mixed EAA Pulses, 15g EAA Bolus supplemented with 3g Arginine
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Chronic Kidney Diseases
Effect of Protein Restriction Plus EAA/KA Supplementation on GFR Decline in CKD
This study aims to investigate the effect of protein restriction plus KA/EAA supplementation on GFR decline in CKD patients.
- Trial name
- NCT05952544
- Testing
- essential amino acids and keto-analogues supplementation, low protein diet
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Alexandria University
Amino Acid Plasma Profile
Dairy and Plant Amino Acid Uptake. An Explorative Study
To optimize the environmental sustainability, a protein transition to more plant-based protein sources is required. However, the protein quality of plant-based sources is lower than that of the dairy proteins casein and whey…
- Trial name
- DaPa (NCT05813769)
- Testing
- Dairy protein, Plant protein
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- FrieslandCampina
Sarcopenia
Nutritional and Contractile Regulation of Muscle Growth
Muscle wasting, which involves the loss of muscle tissue, is common in many conditions, such as cancer, AIDS, trauma, kidney failure, bone fracture, and sepsis.
- Trial name
- NCT00891696
- Testing
- Rapamycin, Amino acid supplementation, Low-intensity resistance exercise
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Stunting
Food-based Approach Development to Fulfil Amino Acid Gap by Considering the Intestinal Permeability of Children
This study will be comprised of 2 phases. Phase 1 study is a comparative cross-sectional study which will be conducted among children aged 12-24 months living in agricultural area.
- Trial name
- NCT04157413
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Nia Novita Wirawan