Clinical trials: Amoxicillin
Aggressive Periodontitis, Generalized
Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis
The aim of this project is to compare the efficacy and the local effect of the association of single or repeated application of photodynamic therapy (PDT) with antibiotic agents using Amoxicillin + Metronidazole or Clarithromycin…
- Trial name
- NCT03132714
- Testing
- Full-mouth ultrasonic debridement, Amoxicillin 500mg, Metronidazole 400mg
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Periodontal Diseases, Antibiotics
Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies
Periodontitits is a bacteria induced inflammatory disease that destroys the supporting tissues of the tooth and leads to tooth loss.
- Conditions
- Periodontal Diseases, Antibiotics, Pharmacokinetics
- Trial name
- AMA (NCT04669717)
- Testing
- 3/d 500 mg Amoxicilline Sandoz plus 500 mg Flagyl for 7 days, 3/d 500 mg Amoxicilline Sandoz plus 500 mg Flagyl for 3 days, 1/d 500 mg Azithromycine Pfizer for 3 days
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Bronchitis, Acute, Community-acquired Pneumonia
Multimodal Stewardship Programme to Improve Antibiotic Prescribing for Children With Lower Respiratory Tract Infections
Children with lower respiratory tract infection (LRTI) are still often prescribed antibiotics in ways that depart from national guidelines.
- Conditions
- Bronchitis, Acute, Community-acquired Pneumonia, Respiratory Tract Infections
- Trial name
- PRACTICE-LRTI (NCT07893834)
- Testing
- PRACTICE-LRTI multimodal antimicrobial stewardship programme
- Where
- Finland
- Volunteers
- 50,000 people
- Sponsor
- Tampere University
Helicobacter
7-day High-Dose Vonoprazan-amoxicillin Dual Therapy Versus 14-day Vonoprazan-amoxicillin Dual Therapy for H. Pylori
Helicobacter pylori infection is a prevalent global gastrointestinal condition linked to chronic gastritis, peptic ulcer disease, and gastric cancer. Potent and sustained acid suppression improves eradication efficacy.
- Trial name
- NCT07352098
- Testing
- 7-day high-dose vonoprazan-amoxicillin dual therapy group, 14-day vonoprazan-amoxicillin dual therapy group
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Yueyue Li
Helicobacter Pylori Infection
Efficacy and Safety of Dual Therapy for Helicobacter Pylori Eradication
The purpose of this study was to evaluate the Efficacy and Safety of Vonoprazan- amoxicillin dual therapy for Helicobacter Pylori eradication
- Trial name
- NCT05469685
- Testing
- Vonoprazan, Amoxicillin
- Where
- 10 sites in China
- Volunteers
- 914 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Amoxicillin Allergy
Diagnosing Drug Allergy: the T is the Key
The goal of this clinical trial is to validate a newly developed test in the diagnosis of patients with amoxicillin allergy (i.e. T-cell activation test).
- Trial name
- TAT (NCT06409884)
- Testing
- T-cell activation test using intracellular markers
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Helicobacter Pylori
Vonoprazan-Based Triple Therapy in Comparison With Extended Sequential Therapy
This study aims to compare the efficacy of the current standard first-line anti-helicobacter pylori regimen, extended proton pump inhibitor-based sequential therapy, with that of vonoprazan-based triple therapy, through a…
- Trial name
- NCT05371249
- Testing
- Vonoprazan-based triple therapy, Extended sequential therapy
- Where
- Taiwan
- Volunteers
- 628 people
- Sponsor
- Fu Jen Catholic University Hospital
Peri-implantitis, Periodontal Diseases
Systemic Amoxicillin Plus Metronidazole in Peri-implantitis Treatment
The primary objective of this controlled clinical trial is to evaluate the clinical effect of systemic amoxicillin plus metronidazole therapy in conjunction with initial non-surgical treatment of peri-implantitis.
- Trial name
- NCT04149327
- Testing
- amoxicillin 500 mg + metronidazole 500 mg, non-surgical periodontal and peri-implant treatment
- Volunteers
- 62 people
- Sponsor
- University Medical Center Groningen
Community-acquired Pneumonia (CAP)
Efficacy of High Doses Penicillin V Versus High Doses Amoxicillin in the Treatment of Non-severe Pneumonia.
This study aims to evaluate wether high-dose penicillin V is as effective as high-dose amoxicillin for the treatment of non-sever community-acquired pneumonia (CAP).
- Trial name
- PENIPNEUMO (NCT03208361)
- Testing
- Penicillin V, Amoxicillin
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Tuberculosis, Pulmonary
The BLAST- 1 Trial - Cephalexin+Amoxicillin-clavulanate for Tuberculosis
The goal of this randomized controlled trial is to study the early bactericidal activity in adult patients with smear-positive pulmonary tuberculosis.
- Trial name
- BLAST (NCT05664568)
- Testing
- Cephalexin, Amoxicillin-Clavulanate 500 Mg-125 Mg Oral Tablet, Standard of care treatment of tuberculosis
- Where
- 3 sites in Australia
- Volunteers
- 30 people
- Sponsor
- Western Sydney Local Health District
Fast Breathing in Young Infants
Community Based Management of Fast Breathing in Infants Aged < 60 Days in Low-income Settlements of Karachi
The aim of the study is to determine optimal management of isolated fast breathing in young infants in a trial design conducted in primary care settings.
- Trial name
- MAT-YI (NCT01533818)
- Testing
- Amoxicillin, Sugar Syrup
- Where
- Pakistan
- Volunteers
- 963 people
- Sponsor
- Aga Khan University