Clinical trials: Amphetamine-Related Disorders
Mood Disorder, Substance-Related Disorders
Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)
The purpose of this study is to determinate the effect of a pre-treatment with carvedilol, a alpha- and beta-adrenergic receptor blocker, on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA…
- Conditions
- Mood Disorder, Substance-Related Disorders, Amphetamine-Related Disorders
- Trial name
- NCT01270672
- Testing
- 3,4-Methylenedioxymethamphetamine, carvedilol
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Mood Disorder, Substance-Related Disorders
Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)
The purpose of this study is to determinate the effect of a pre-treatment with doxazosin, a alpha1-adrenergic receptor blocker, on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").
- Conditions
- Mood Disorder, Substance-Related Disorders, Amphetamine-Related Disorders
- Trial name
- NCT01386177
- Testing
- 3,4-Methylenedioxymethamphetamine, Doxazosin
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Amphetamine Addiction
The Application of Music Therapy in Female Amphetamine Use Disorder
The group music therapy will be used to treat female amphetamine-type stimulant (ATS) addiction
- Trial name
- NCT03221283
- Testing
- Music therapy group
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Mental Health Center
Methamphetamine Addiction, Crystal Meth Addiction
An Assessment of the Safety of Varenicline in Methamphetamine-dependent Volunteers
More people worldwide use amphetamine-type stimulants than any illicit drug besides cannabis, and methamphetamine (MA) abuse and dependence is the fastest growing drug problem in the United States.
- Conditions
- Methamphetamine Addiction, Crystal Meth Addiction, Amphetamine Addiction
- Trial name
- NCT00713479
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Los Angeles
Amphetamine-Related Disorders
Mirtazapine for the Treatment of Methamphetamine Dependence Among MSM (M2.0)
The investigators recently conducted a double-blind, randomized controlled trial (n=60) of limited duration (12 weeks), and found that compared with placebo, oral mirtazapine, an FDA-approved antidepressant, significantly reduced…
- Trial name
- NCT01888835
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Phillip Coffin, MD, MIA
Amphetamine Dependence
Extended Release Naltrexone for Treating Amphetamine Dependence in Iceland
Until positive results were found with oral naltrexone, no medication has been effective against amphetamine dependence. The primary aim of this pilot study is to replicate the findings of the Swedish team that showed oral…
- Trial name
- NCT01100853
- Where
- Iceland
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
Amphetamine-Related Disorders
Tyrosine for Methamphetamine Dependence - 1
The purpose of this study is to evaluate efficacy of tyrosine as a treatment for methamphetamine dependence in an outpatient treatment setting providing group psychosocial interventions.
- Trial name
- NCT00000322
- Testing
- Tyrosine
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Ondansetron for the Treatment of Methamphetamine Dependence - 1
The purpose of this study is to assess ondansetron for the treatment of methamphetamine dependence.
- Trial name
- NCT00040053
- Testing
- Ondansetron
- Where
- 6 sites in United States
- Volunteers
- 154 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Bupropion for the Treatment of Methamphetamine Dependence - 1
The purpose of this study is to assess the efficacy and safety of bupropion in reducing methamphetamine use in subjects with methamphetamine dependence
- Trial name
- NCT00069251
- Testing
- Bupropion
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Cognitive Correlates of Substance Abuse - 11
The purpose of this study is to characterize the cognitive performance of methamphetamine abusers by comparing them with cocaine abusers and normal controls.
- Trial name
- NCT00000346
- Testing
- counseling
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders, Tobacco Use Disorder
Effects of Stimulant Dependence on Human Striatal Dopamine System - 15
The purpose of this study is to determine whether DAT availability, assessed by WIN binding, in the striatum is altered in cocaine or methamphetamine dependence.
- Trial name
- NCT00000350
- Testing
- radioactive substance
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Cognitive Correlates of Substance Abuse, Part 2 - 16
Part II: Examine cognitive performance of stimulant abusers (methamphetamine and cocaine) during recovery by assessing their cognitive function at monthly intervals.
- Trial name
- NCT00000351
- Volunteers
- 43 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Assessment of Potential Interactions Between Methamphetamine and Selegiline - 1
The purpose of this study is to assess the potential interactions between intravenous methamphetamine and oral selegiline.
- Trial name
- NCT00033072
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Assessment of Potential Interactions Between Methamphetamine and Bupropion - 1
The purpose of this study is to assess potential interactions between intravenous (IV) methamphetamine and oral bupropion.
- Trial name
- NCT00040040
- Testing
- Bupropion
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Assessment of Interactions Between Methamphetamine and Aripiprazole - 1
The purpose of this study is to assess the interactions between intravenous methamphetamine and aripiprazole.
- Trial name
- NCT00089440
- Testing
- Aripiprazole
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
To Assess the Safety and Tolerability of 7.5, 15 and 30 mg of Sublingual Lobeline. - 1
To assess the safety and tolerability of 7.5, 15 and 30 mg of sublingual lobeline.
- Trial name
- NCT00100074
- Testing
- Lobeline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
Assessment of Interactions Between Intravenous Methamphetamine and Modafinil - 1
The purpose of this study is to assess the potential interactions between intravenous methamphetamine and oral Modafinil.
- Trial name
- NCT00265278
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders
A Phase 1 Parallel-Group, Double-Blind, Placebo-Controlled Cardiovascular and Behavioral Study Assessing Interactions Between Single Doses of Oral Reserpine and Intravenous Methamphetamine - 1
In this parallel group clinical pharmacology laboratory experiment, we will assess pharmacodynamic interactions (with a focus on cardiovascular effects) of a 15 mg intravenous methamphetamine dose and single oral doses of…
- Trial name
- NCT00267657
- Testing
- Reserpine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine-Related Disorders, HIV
Contingency Management for Methamphetamine Abstinence and HIV Post-Exposure Prophylaxis in Men Who Have Sex With Men
This study seeks to decrease methamphetamine use and concomitant high-risk sexual behaviors among methamphetamine-using men who have sex with men (MSM) by combining a biomedical intervention with a behavioral intervention.
- Conditions
- Amphetamine-Related Disorders, HIV, HIV Infections
- Trial name
- NCT00856323
- Testing
- Truvada, CM
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Friends Research Institute, Inc.
Substance-Related Disorders, Alcohol-Related Disorders
Conflict Between Maternal Autonomy and Child Health in Substance-use
Qualitative project, comprising open-ended semi-structured interviews with healthcare workers, who provide antenatal care to substance-using women.
- Conditions
- Substance-Related Disorders, Alcohol-Related Disorders, Amphetamine-Related Disorders, Inhalant Abuse
- Trial name
- NCT02797990
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine