Clinical trials: Amphetamine-Related Disorders
Amphetamine Addiction
The Diagnostic Assessment and Intervention Study of Amphetamine Type Stimulus
The purpose of this research is to inspire new medical ideas using brain image technology for the treatment of Amphetamine Type Stimulus addition, at the same time lowing the addition damage.
- Trial name
- NCT02285556
- Testing
- psychological rehabilitation training, physical and neurological rehabilitation training, rTMS 10HZ high frequency stimulation
- Where
- China
- Volunteers
- 560 people
- Sponsor
- Shanghai Mental Health Center
Substance-Related Disorders, Alcohol-Related Disorders
Conflict Between Maternal Autonomy and Child Health in Substance-use
Qualitative project, comprising open-ended semi-structured interviews with healthcare workers, who provide antenatal care to substance-using women.
- Conditions
- Substance-Related Disorders, Alcohol-Related Disorders, Amphetamine-Related Disorders, Inhalant Abuse
- Trial name
- NCT02797990
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Schizophrenia, Schizoaffective Disorder
Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia
It is hypothesized that the atypical antipsychotic, Seroquel, will cause significant reduction in drug and alcohol cravings in patients with schizophrenia and comorbid cocaine and/methamphetamine dependence compared to the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Substance Abuse, Substance Dependence
- Trial name
- NCT00208143
- Testing
- Quetiapine, Risperidone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Creighton University
Healthy Volunteers, Drug Users
A Study to Evaluate the Abuse Potential of EB-1020 Immediate-Release in Healthy Recreational Stimulant Users
This single-center study will be a single-dose, randomized, double-blind, placebo- and active-controlled crossover study with a single inpatient treatment visit.
- Trial name
- NCT02144415
- Testing
- EB-1020 400 mg, EB-1020 800 mg, lisdexamfetamine 150 mg
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Amphetamine Addiction
The Novel Addiction Assessment Study in Synthetic Drugs Addiction
The purpose of this research is to develop an objective assessment based on the virtual reality techniques which is used for evaluate addiction severity.
- Trial name
- NCT02950376
- Testing
- DSM-5 +Virtual reality-based addiction assessment system, Virtual reality-based addiction assessment system
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Amphetamine-Related Disorders
Mirtazapine for the Treatment of Methamphetamine Dependence Among MSM (M2.0)
The investigators recently conducted a double-blind, randomized controlled trial (n=60) of limited duration (12 weeks), and found that compared with placebo, oral mirtazapine, an FDA-approved antidepressant, significantly reduced…
- Trial name
- NCT01888835
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Phillip Coffin, MD, MIA
Heroin Dependence, Amphetamine Dependence
An Open-label Study of Oral Paliparidone for the Treatment of Patients With Co-occurring Opioid and ATS Dependence
The proposed study will evaluate the tolerability, acceptability and potential efficacy of paliparidone for the treatment of co-occurring opioid and amphetamine-type stimulant (ATS) dependence.
- Trial name
- NCT02541513
- Testing
- paliparidone
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- Universiti Sains Malaysia
Amphetamine Addiction
Cannabioids as a New Intervention for Amphetamine Dependence
Addiction to amphetamine is characterized by alternating phases of intoxication and short abstinence, followed by recurrent drug-craving episodes which result in distress and relapse.
- Trial name
- NCT02952196
- Testing
- drug administration
- Where
- Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Opioid-use Disorder, Amphetamine Use Disorders
Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder
Chronic drug addiction is not only associated with increased mental health symptoms, such as anxiety and depression, but also with brain (neural and cognitive) deficits.
- Trial name
- NEAT (NCT03922646)
- Testing
- Neurocognitive Empowerment for Addiction Treatment (NEAT), Active Control
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Amphetamine-Related Disorders
A Cognitive Behavioral Therapy-Based Text Message Intervention for Methamphetamine Dependence
This Phase I behavior therapy development study seeks to improve treatment outcomes for methamphetamine (MA)-dependent subjects by developing a novel cognitive behavioral therapy- (CBT-) based short message service (SMS) text…
- Trial name
- NCT01899313
- Testing
- CBT- based SMS text messaging intervention, CBT group therapy
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- California Pacific Medical Center Research Institute
Amphetamine-Related Disorders
Ondansetron for the Treatment of Methamphetamine Dependence - 1
The purpose of this study is to assess ondansetron for the treatment of methamphetamine dependence.
- Trial name
- NCT00040053
- Testing
- Ondansetron
- Where
- 6 sites in United States
- Volunteers
- 154 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cocaine Addiction
Dexamphetamine Sustained Release Pharmacokinetics and Clinical Validation of Dried Blood Spots
The pharmacokinetics of 10 to 12 individuals receiving 60 mg of sustained release dexamphetamine will be studied. These individuals have received this medication before in a previous trial where the pharmacodynamics were…
- Trial name
- NCT02768441
- Testing
- Dexamphetamine
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- The Netherlands Cancer Institute
Bipolar II Disorder
Differential Responses to Drugs and Sweet Tastes
Young adults who exhibit "bipolar phenotype" (BPP), defined as occasional episodes of mood elevation and heightened activity, are at risk for several psychiatric disorders, including problem use of drugs and alcohol.
- Trial name
- HAP (NCT03810703)
- Testing
- d-amphetamine 10 mg oral capsule, d-amphetamine 20 mg oral capsule
- Where
- 2 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Amphetamine-Related Disorders
Assessment of Potential Interactions Between Methamphetamine and Selegiline - 1
The purpose of this study is to assess the potential interactions between intravenous methamphetamine and oral selegiline.
- Trial name
- NCT00033072
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amphetamine Use Disorders, Amphetamine Use Disorder
Effects of Repetitive Transcranial Magnetic Stimulations in Patients With Amphetamine Use Disorders
Amphetamine Use Disorder (AUD) is a major public health issue in Taiwan, where it is the most commonly abused illegal drug. There are currently no effective approved medications to treat it, which makes finding new treatment…
- Conditions
- Amphetamine Use Disorders, Amphetamine Use Disorder, Amphetamine Dependence, Amphetamine Abuse
- Trial name
- NCT06960265
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- TsaoTun Psychiatric Center, Department of Health, Taiwan
Methamphetamine-dependence, Substance Abuse
Safety Interaction Trial Ibudilast and Methamphetamine
This study is designed to collect data to determine whether a medication, ibudilast, is safe for use as a potential treatment for methamphetamine-dependent people.
- Trial name
- NCT01217970
- Testing
- Ibudilast 20mg, Ibudilast 50mg
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, Los Angeles
Amphetamine Abuse, Amphetamine Dependence
Combination of Psychosocial Intervention and Slow Prosecutions for the Treatment of Methamphetamine Abuse/Dependence
The hospital where this study will be conducted is responsible for the one-year contingency management treatment for methamphetamine drug offenders referred from the Yunlin District Prosecutors Office.
- Conditions
- Amphetamine Abuse, Amphetamine Dependence, Methamphetamine Abuse, Methamphetamine Dependence
- Trial name
- NCT01273701
- Testing
- Psychosocial intervention, Telephone reminding
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Amphetamine Addiction, Pharmacotherapy
Dextromethorphan, Memantine Monotherapy, or Combined Use of Dextromethorphan and Memantine in Amphetamine Addiction
The investigators will conducted a randomized double-blind placebo-controlled study to investigate the treatment outcomes of add-on low dose dextromethorphan (DM), memantine (MM), or dextromethorphan and memantine combination…
- Trial name
- NCT04687566
- Testing
- Dextromethorphan, Memantine, Dextromethorphan and memantine
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Cheng-Kung University Hospital
Amphetamine Dependence
Trial of Modafinil for Methamphetamine Dependence
The study aims to evaluate the safety and efficacy of modafinil (200 mg/day) over 10 weeks plus a tailored cognitive behavioural therapy program in the treatment of methamphetamine dependence.
- Trial name
- NCT00123370
- Testing
- Modafinil
- Where
- 2 sites in Australia
- Volunteers
- 87 people
- Sponsor
- The University of New South Wales
Amphetamine-Related Disorders, HIV
Contingency Management for Methamphetamine Abstinence and HIV Post-Exposure Prophylaxis in Men Who Have Sex With Men
This study seeks to decrease methamphetamine use and concomitant high-risk sexual behaviors among methamphetamine-using men who have sex with men (MSM) by combining a biomedical intervention with a behavioral intervention.
- Conditions
- Amphetamine-Related Disorders, HIV, HIV Infections
- Trial name
- NCT00856323
- Testing
- Truvada, CM
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Friends Research Institute, Inc.