Clinical trials: Amphetamine-Related Disorders
Substance Use Disorders
CDP-choline Treatment in ATS Users
This study is a 12-week, randomized, double-blind, placebo-controlled trial of cytidine-5'-diphosphate choline in amphetamine-type stimulants-using adolescents.
- Trial name
- NCT02630069
- Testing
- CDP-choline, Supportive psychotherapy
- Where
- South Korea
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital
Craving, Depression, Anxiety
Repetitive Transcranial Magnetic Stimulation in Amphetamine Addiction
The study aims to test whether transcranial magnetic stimulation (TMS) improves the craving, depression, anxiety and cognitive function during the abstinent period of methamphetamine users.
- Conditions
- Craving, Depression, Anxiety, Amphetamine Addiction
- Trial name
- NCT04993300
- Testing
- transcranial magnetic stimulation (TMS)
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Amphetamine Abuse, Amphetamine Dependence
A Pilot Study of Citicoline add-on Therapy in Patients With Bipolar Disorder or Major Depressive Disorder and Amphetamine Abuse or Dependence
Bipolar disorder (BD) is a common and severe psychiatric illness. Drug and alcohol abuse are very common in people with BD and other mood disorders and are associated with increased rates of hospitalization, violence towards self…
- Conditions
- Amphetamine Abuse, Amphetamine Dependence, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT00377299
- Testing
- Citicoline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Mood Disorder, Substance-Related Disorders
Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)
The purpose of this study is to determinate the effect of a pre-treatment with doxazosin, a alpha1-adrenergic receptor blocker, on the pharmacodynamics and pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").
- Conditions
- Mood Disorder, Substance-Related Disorders, Amphetamine-Related Disorders
- Trial name
- NCT01386177
- Testing
- 3,4-Methylenedioxymethamphetamine, Doxazosin
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Schizophrenia, Schizoaffective Disorder
Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia
It is hypothesized that the atypical antipsychotic, Seroquel, will cause significant reduction in drug and alcohol cravings in patients with schizophrenia and comorbid cocaine and/methamphetamine dependence compared to the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Substance Abuse, Substance Dependence
- Trial name
- NCT00208143
- Testing
- Quetiapine, Risperidone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Creighton University
Amphetamine-Related Disorders
Assessment of Interactions Between Methamphetamine and Aripiprazole - 1
The purpose of this study is to assess the interactions between intravenous methamphetamine and aripiprazole.
- Trial name
- NCT00089440
- Testing
- Aripiprazole
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Opioid-Related Disorders, Stimulant-Related Disorder
Preventing Parental Opioid and/or Methamphetamine Addiction Within DHS-Involved Families: PRE-FAIR
Young parents aged 16 to 30, involved in the DHS system for child welfare or self-sufficiency needs are at risk for opioid use disorder and/or methamphetamine use disorder (OUD; MUD).
- Conditions
- Opioid-Related Disorders, Stimulant-Related Disorder, Child Neglect, Mental Health Impairment
- Trial name
- PRE-FAIR (NCT05380440)
- Testing
- Prevention Adaptation of Families Actively Improving Relationships (PRE-FAIR), Standard Case Management and Referral
- Where
- United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Chestnut Health Systems
Amphetamine-related Disorders
Long-term Behavior Change - 1
The purpose of this study is to determine if different reinforcement procedures (i.e., schedules) produce different patterns of long-term abstinence from methamphetamine.
- Trial name
- NCT00158197
- Testing
- contingency management voucher
- Where
- 2 sites in United States
- Volunteers
- 119 people
- Sponsor
- Friends Research Institute, Inc.
Heroin Dependence, Amphetamine Dependence
An Open-label Study of Oral Paliparidone for the Treatment of Patients With Co-occurring Opioid and ATS Dependence
The proposed study will evaluate the tolerability, acceptability and potential efficacy of paliparidone for the treatment of co-occurring opioid and amphetamine-type stimulant (ATS) dependence.
- Trial name
- NCT02541513
- Testing
- paliparidone
- Where
- Malaysia
- Volunteers
- 40 people
- Sponsor
- Universiti Sains Malaysia
Amphetamine-Related Disorders
Implementation and Effectiveness of Multidiscipline-Integrated Addiction Treatment Model
Management of substance use disorders in clinical settings is challenging. Approaches with integrated bio-psycho-social interventions, along with the engagement of families and self-help groups are strongly recommended.
- Trial name
- NCT04203654
- Testing
- cognitive-behavior group therapy, Individual supportive psychotherapy
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- National Health Research Institutes, Taiwan
Amphetamine-Related Disorders
Ondansetron for the Treatment of Methamphetamine Dependence - 1
The purpose of this study is to assess ondansetron for the treatment of methamphetamine dependence.
- Trial name
- NCT00040053
- Testing
- Ondansetron
- Where
- 6 sites in United States
- Volunteers
- 154 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cocaine Addiction
Dexamphetamine Sustained Release Pharmacokinetics and Clinical Validation of Dried Blood Spots
The pharmacokinetics of 10 to 12 individuals receiving 60 mg of sustained release dexamphetamine will be studied. These individuals have received this medication before in a previous trial where the pharmacodynamics were…
- Trial name
- NCT02768441
- Testing
- Dexamphetamine
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- The Netherlands Cancer Institute
Amphetamine-Related Disorders, HIV
Contingency Management for Methamphetamine Abstinence and HIV Post-Exposure Prophylaxis in Men Who Have Sex With Men
This study seeks to decrease methamphetamine use and concomitant high-risk sexual behaviors among methamphetamine-using men who have sex with men (MSM) by combining a biomedical intervention with a behavioral intervention.
- Conditions
- Amphetamine-Related Disorders, HIV, HIV Infections
- Trial name
- NCT00856323
- Testing
- Truvada, CM
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Friends Research Institute, Inc.
Amphetamine Addiction
The Diagnostic Assessment and Intervention Study of Amphetamine Type Stimulus
The purpose of this research is to inspire new medical ideas using brain image technology for the treatment of Amphetamine Type Stimulus addition, at the same time lowing the addition damage.
- Trial name
- NCT02285556
- Testing
- psychological rehabilitation training, physical and neurological rehabilitation training, rTMS 10HZ high frequency stimulation
- Where
- China
- Volunteers
- 560 people
- Sponsor
- Shanghai Mental Health Center
Bipolar Depression
8 Week Multi-site Study of MYDAYIS® for Bipolar Depression
This protocol is a Phase 2 multi-site study which aims to evaluate the safety and effectiveness of MYDAYIS\® as adjunctive therapy for adults with bipolar depression.
- Trial name
- NCT04235686
- Testing
- Mydayis Extended-Release Capsule
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- Mayo Clinic
Chronic Pain, Post-traumatic Stress Disorder
The Norwegian Addiction, Pain and Trauma Study
In populations with substance use disorders (SUD), there is a high prevalence of chronic pain with various underlying causes. Chronic pain can complicate the treatment of SUD and lead to poorer treatment outcomes.
- Conditions
- Chronic Pain, Post-traumatic Stress Disorder, Substance Use Disorders
- Trial name
- NOR-APT (NCT04908410)
- Where
- 4 sites in Norway
- Volunteers
- 1,650 people
- Sponsor
- University Hospital, Akershus