Clinical trials: Amplitude
Diabetes Mellitus
Effects of Acarbose Versus Glibenclamide on MAGE and Oxidative Stress in Patients With Type 2 DM
To compare effect of acarbose versus glibenclamide treatment on mean amplitude of glyclemic excursion and oxidative stress in diabetes individuals who failed to control their glucose by metformin therapy alone
- Trial name
- NCT00417729
- Testing
- Acarbose
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Taichung Veterans General Hospital
Muscle Weakness
Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness
The goal of this trial was to determine if a mid-thoracic high velocity low amplitude spinal manipulation improves force output in those with unilateral hip adductor weakness.
- Trial name
- NCT06534931
- Testing
- High velocity low amplitude thoracic spine manipulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New England
Sudden Cardiac Death, Sudden Cardiac Arrest
Low QRS Voltages in Young Healthy Individuals and Athletes
There is some limited evidence that reduced size of electrical complexes/traces of the heart on the electrocardiogram (ECG) may be associated with scarring in the heart muscle, which may predispose to serious life-threatening…
- Conditions
- Sudden Cardiac Death, Sudden Cardiac Arrest, Sudden Cardiac Death Due to Cardiac Arrhythmia, Arrhythmogenic Right Ventricular Cardiomyopathy
- Trial name
- NCT05799833
- Testing
- Cardiovascular magnetic resonance scan - 3T scanner (Siemens Vida)
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Regional Blood Flow, Premature Birth
Common Neonatal Procedures Could Affect the aEEG in <30 Weeks of Gestational Age Preterms
Very low birth weight infants has increased dramatically their survival. Survival without neurologic disturbance varies a lot between centers.There is evidence that fluctuations in cerebral blood flow influences the appearance of…
- Conditions
- Regional Blood Flow, Premature Birth, Electroencephalography
- Trial name
- ELECTROPREM (NCT00722033)
- Testing
- 3 protocols of Indomethacin administration
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Advanced Hepatocellular Carcinoma
Phase I/II Study of Amplitude-Modulated Electromagnetic Fields in the Treatment of Advanced Hepatocellular Carcinoma
The goal of this study is to investigate the safety and feasibility of treating patients with advanced hepatocellular carcinoma with a noninvasive device administering low level of amplitude-modulated electromagnetic fields.
- Trial name
- TheraBionic (NCT00534664)
- Testing
- TheraBionic device
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Overactive Bladder
Clinical Trial to Study a Non-invasive Neurostimulation Device on Urgency (Urinary) Incontinence Overactive Bladder (OAB)
The purpose of this study is to determine whether the non-invasive neurostimulation patch is effective in the treatment of urgency, frequency and urge (urinary) incontinence.
- Trial name
- NCT01125722
- Testing
- Non-invasive neurostimulation device
- Where
- 11 sites in United States, Sweden and 1 more
- Volunteers
- 74 people
- Sponsor
- Ethicon Endo-Surgery
Postoperative Pulmonary Atelectasis, Morbid Obesity
Perioperative Diaphragmatic Ultrasound as Predictive Index of Atelectasis in Bariatric Surgery
In this study the Authors assume that peri-operative changes in DIA are predictive of postoperative atelectasis, thus providing a clinically useful tool to stratify the need for high-intensity monitoring, including admission to…
- Trial name
- ECODIA (NCT04701541)
- Testing
- Diaphragmatic Ultrasound
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Primary or Metastatic Tumor in the Liver Parenchyma
Exploratory Study to Determine Tissue Alterations of Advanced Hepatocellular Carcinoma Induced by Electromagnetic Waves of Low Energy Amplitude Modulated to Specific Frequencies During Imaging Study by MRI
This is an exploratory, national, single-center, open-label study, being conducted at the Institute of Education and Research of the Syrian-Lebanese Hospital in collaboration with the Radiology Institute, the Heart Institute of…
- Trial name
- NCT02692365
- Testing
- Magnetic Resonance + hemodynamic + infusion of gadolinium
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Sirio-Libanes
Tremor, Limb
Effects of High Amplitude and Focused tACS on Entraining Physiological Tremor
Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method that works by passing alternating electric current between electrodes where at least one of them is attached to the head.
- Trial name
- NCT03337334
- Testing
- tACS at tremor frequency
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Cochlear Implant
Establish a Concordance Between the Mismatch Negativity Amplitude and a Score of Logatoms Discrimination
A cochlear implant is a device for the rehabilitation of severe to profound hearing loss. Despite the standardization of surgical procedures and rehabilitation, speech discrimination performance varied significantly in cochlear…
- Trial name
- EVODA-ICMN (NCT03025386)
- Testing
- logatoms test, Electroencephalography
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Surgery
The Effect of Increasing Current or Pulse Duration on Patient Movement and Intraoperative Transcranial Electric Stimulation Motor Evoked Potential Amplitude
Transcranial electric stimulation (TES) motor evoked potential (MEP) monitoring is standard during surgery risking motor system injury. The stimuli are typically 5-pulse trains with a 4 ms interstimulus interval (ISI).
- Trial name
- CCCV (NCT05375669)
- Testing
- ISIS IOM System
- Where
- Switzerland
- Volunteers
- 31 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Thyroid Related Orbitopathy
Pascal Pascal Dynamic Contour Tonometer (DCT) Intraocular Pressure and Ocular Pulse Amplitude in Patients With Thyroid Related Orbitopathy: A Comparison to Goldmann Tonometer and to Muscles Characteristics on CT Scan
Thyroid related orbitopathy (TRO) is an autoimmune disease. Clinical features include: orbital pressure pain, ocular soft tissue swelling, muscle enlargement around the eyeball, eyelid retraction and bulging of the eye anteriorly…
- Trial name
- NCT00646295
- Testing
- To measure the IOP (with Goldmann and Pascal DCT tonometers) and OPA (with Pascal DCT) in primary and upright gazes
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Chronic Neuropathic Pain in the Low Back and Legs
Field Shape and Amplitude Sensitivity Exploratory Study (CONTOUR Study)
The study aims to better understand how to program Spinal Cord Stimulation for the treatment of chronic low back and leg pain
- Trial name
- NCT02916498
- Testing
- Boston Scientific's Precision SPECTRA™ Spinal Cord Stimulation System
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- Boston Scientific Corporation
Gender Role Disorder, Male to Female Type
Gender-specific aEEGs and Outcome in Preterms
Background and objectives: Male sex is a risk factor for poor neurodevelopmental outcome following preterm birth. The investigators aimed to investigate gender-related differences in amplitude-integrated electroencephalography…
- Trial name
- NCT01562236
- Where
- Austria
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Parkinson's Disease, Treadmill
Amplitude and Rate of Intrinsic Feedback During Treadmill Training for Parkinson's Disease
Treadmill training has been shown to be beneficial for reducing motor symptoms of Parkinson's disease (PD). The mechanisms for the therapeutic effects of treadmill training remain unknown.
- Trial name
- NCT01987557
- Testing
- rate group, magnitude treadmill group, regular treadmill walking
- Volunteers
- 48 people
- Sponsor
- Wilfrid Laurier University
Polyneuropathies, Electromyography
Single-Center Study Evaluating the Impact of Age on the Diagnostic Performance of the Sural-to-Radial Sensory Amplitude Ratio in Length-Dependent and Non-Length-Dependent Peripheral Polyneuropathies
This retrospective single-center observational study will evaluate the impact of age on the diagnostic performance of the sural-to-radial sensory nerve amplitude ratio (SRAR) in patients with length-dependent and…
- Conditions
- Polyneuropathies, Electromyography, Diagnostic Techniques
- Trial name
- ASPIRE (NCT07725120)
- Testing
- Retrospective Medical Record Review
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pain, Back
Spinal Segment MRI Perfusion and Diffusion Response to Spinal Manipulation in Low Back Pain Patients
The main objective is to quantify changes in diffusion and perfusion in the intervertebral disc and adjacent spinal muscle tissue of a spinal segment receiving a spinal manipulative or control intervention using…
- Trial name
- NCT03880500
- Testing
- Spinal Manipulative Therapy
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Low Back Pain
H-reflex Responses to High-Velocity Low-Amplitude Manipulation
High-Velocity Low-Amplitude (HVLA) manipulation is a known technique of the Osteopathic Manipulative Treatment (OMT) for somatic dysfunction (SD), and heart rate variability and H-reflex response are possible variables to assess…
- Trial name
- NCT02406807
- Testing
- HVLA manipulation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Osteopatia
Hepatocellular Carcinoma (HCC)
Amplitude-modulated Radiofrequency Electromagnetic Field Treatment for Advanced Hepatocellular Carcinoma (Immune-RF)
Combined double immune checkpoint inhibition and radiofrequency electromagnetic field treatment for patients with advanced hepatocellular carcinoma
- Trial name
- NCT06821958
- Testing
- Radiofrequency electromagnetic field treatment
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Charite University, Berlin, Germany
Low Back Pain
Immediate Effects of a Spinal Lumbar Manipulation
Non-specific low back pain is defined as a pain with no specific vertebral-related cause, such as infectious disease, tumor, osteoporosis, fracture, structural abnormality, inflammatory disease, radicular compressive syndrome or…
- Trial name
- NCT02312778
- Testing
- HVLA Manipulation
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Federal University of Rio Grande do Sul