Clinical trials: Amplitude
Overactive Bladder
Safety and Effectiveness of a Non-invasive Neuromodulation Device on Urgency Urinary Incontinence in Overactive Bladder
The purpose of this study is to evaluate the change from baseline between the active and sham treatment groups in the treatment of urgency (urinary) incontinence episodes (leaks).
- Trial name
- Beacon (NCT01369485)
- Testing
- (VERV™ System)
- Where
- 14 sites in United States
- Volunteers
- 163 people
- Sponsor
- Ethicon Endo-Surgery
Metastatic Pancreatic Adenocarcinoma
Gemcitabine, Nab-paclitaxel Plus the TheraBionic P1 (an Amplitude-Modulated Radiofrequency Electromagnetic Fields) Device to Treat Metastatic Pancreatic Cancer
The goal of this study is to learn if the combination of nab-paclitaxel, gemcitabine and an Amplitude-Modulated Radiofrequency Electromagnetic Fields device (Therabionic P1) is safe and effective for patients with adenocarcinoma…
- Trial name
- NCT06576115
- Testing
- Nab paclitaxel, Gemcitabine, TheraBionic P1
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Mild Cognitive Impairment (MCI), Exercises
High-Amplitude Functional Exercises in Older Adults With Mild Cognitive Impairment
This study will investigate the effects of dual-task-based high-amplitude functional exercises on balance and functional mobility in older adults with mild cognitive impairment.
- Trial name
- NCT07762235
- Testing
- Dual-Task-Based High-Amplitude Functional Exercise Program, Traditional Balance and Mobility Exercise Group
- Volunteers
- 36 people
- Sponsor
- Istinye University
Peripheral Arterial Disease
POWER: Pulse Intravascular Lithotripsy (Pulse IVL) to Open Vessels With Calcific Walls and Enhance Vascular Compliance and Remodeling
The POWER-PAD-1 Study is a first-in-human evaluation of the safety and performance of the Pulse Peripheral Intravascular Lithotripsy (IVL) Balloon Catheter to enroll up to twenty (20) subjects.
- Trial name
- POWER-PAD-1 (NCT05192473)
- Testing
- Pulse Intravascular Lithotripsy System
- Where
- 3 sites in Australia, Dominican Republic and 1 more
- Volunteers
- 9 people
- Sponsor
- Amplitude Vascular Systems, Inc.
Altitude Hypoxia, Neonatal Encephalopathy
Neonatal Electrical Activity at Different Altitude Levels
In this study, the objective is to compare neonatal cerebral electrical activity within 3 days after birth across different altitude areas using amplitude-integrated electroencephalography (aEEG), and establish reference value…
- Trial name
- NCT05966714
- Testing
- aEEG
- Where
- 2 sites in China
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Contracture of Elbow Joint
Immediate Effects of Superficial Heat Associated With Elongation in the Posttraumatic Elbow Contracture
The elbow contracture is a secondary injury that can occur after direct trauma, causing the patient to have limitations in their range of motion.
- Trial name
- NCT03179098
- Testing
- Modified Weeks protocol, CIVM, GC- Sustained Stretching
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Dementia
EEG Biofeedback to Improve Memory in Adults With Dementia
This study measures whether the symptoms of frontotemporal dementia (FTD) can be successfully treated by (a) biofeedback training to increase brain blood flow, (b) biofeedback to increase the frequency of the brain's dominant…
- Trial name
- QMFFTD (NCT01168466)
- Testing
- QEEG-based Neurofeedback Training
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Quietmind Foundation
Sleep
Sleep-wake Patterns in Preterm Infants
The development of sleep-wake behavior is considered to be one of the most important maturation processes occurring in the first year of life.
- Trial name
- NCT04145362
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Mood Disorders, Schizophrenia Spectrum and Other Psychotic Disorders
Low Pulse Amplitude Seizure Therapy (LAP-ST Study)
This study assesses the feasibility of a full course of Low Pulse Amplitude-Seizure Therapy (LAP-ST) (primary outcome).
- Trial name
- NCT02928159
- Testing
- Mecta spectrum 5000Q device
- Volunteers
- 22 people
- Sponsor
- Behman Hospital
Brain Injuries, Congenital Heart Disease
Protecting Brains and Saving Futures - the PBSF Protocol
Background: Multiple neonatal disorders are associated with risks of neurological injury. Thus, management of these infants should involve a coordinated approach to permit early diagnosis with improved clinical care.
- Conditions
- Brain Injuries, Congenital Heart Disease, Newborn Morbidity, Intraventricular Hemorrhage
- Trial name
- PBSF (NCT03786497)
- Where
- 2 sites in Brazil
- Volunteers
- 2,268 people
- Sponsor
- Protecting Brains Saving Futures
Stroke, Hemiplegia
H-reflex Measurement in Hemiplegic Stroke Patients
As human beings live longer, geriatric disease develop, one of which was stroke whose prevalence elevated by aging. Increased spasticity is a common symptom after stroke and may hinder patient from rehabilitation.
- Conditions
- Stroke, Hemiplegia, Spasticity as Sequela of Stroke
- Trial name
- NCT04977531
- Volunteers
- 60 people
- Sponsor
- Heng-Yi, Shen
Brain Activity, Neurodevelopmental Outcome
Analysis of Correlation of Amplitude-Integrated EEG and Neurodevelopmental Outcome in Preterm Infants
The study included analysis of longitudinal recordings of amplitude-integrated EEG (aEEG) tracings on a weekly basis in preterm infants and evaluation of their neurodevelopmental outcome at the age of three years.
- Trial name
- NCT00728234
- Testing
- aEEG recording
- Where
- Austria
- Volunteers
- 284 people
- Sponsor
- Medical University of Vienna
Brachial Plexus Block, Oximetry
Assessment of the C8 Dermatomal Block with Photoplethysmographic Amplitude After Interscalene Brachial Plexus Block
The goal of this clinical trial is to investigate the effectiveness of photoplethysmographic amplitude in assessing the extent of anesthesia in the 8th cervical dermatome in patients undergoing interscalene brachial plexus block…
- Trial name
- NCT06015204
- Testing
- Interscalene brachial plexus block targeting the C5-to-C6 nerve roots, Interscalene brachial plexus block targeting the C5-to-C8 nerve roots
- Where
- South Korea
- Volunteers
- 98 people
- Sponsor
- JongHae Kim
Ankle Joint Contracture, Knee Injuries and Disorders
Immediate Effects of Two Ankle Mobilization Techniques in the Amplitude of Dorsiflexion and Dynamic Valgus Knee
Dynamic knee valgus is an inadequate biomechanical movement of multifactorial cause that may expose the individual to various injuries. The range of motion of ankle dorsiflexion is one of the possible influencing factors.
- Trial name
- NCT03171233
- Testing
- Mobilization with movement, Self mobilization with movement
- Where
- Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Ceara
Subluxation
Patient Perceptions Following a Single Session of Simulated or Genuine HVLA Manual Chiropractic Adjustments
The primary aim of this trial is to assess blinding following simulated/sham or genuine/real high velocity, low amplitude (HVLA) manual chiropractic adjustments.
- Trial name
- SHA (NCT06153290)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Life University
Intubation
A Study Of T1/Tref Intubating Conditions
The purpose of this study is to determine the maximum ratio of the twitch amplitude (T1) to the reference twitch (Tref) amplitude (T1/Tref) that provides excellent intubating conditions.
- Trial name
- NCT07483164
- Testing
- Twitch amplitude <0.1, Twitch amplitude <0.3, Twitch amplitude <0.5
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Mayo Clinic
Stroke
Electrotactile Frequency, Amplitude, and Temporal Gap Discrimination in Young Adults, Older Adults, and Stroke Survivors
The purpose of this study is to evaluate and compare sensory discrimination ability for electrotactile stimulation among young adults, older adults, and patients with stroke.
- Trial name
- ESD-NR (NCT07656675)
- Testing
- Electrotactile Sensory Discrimination Tasks
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sungkyunkwan University
Stroke
Amplitude Modulation Frequency Comparison in Kilohertz Transcranial Magnetic Perturbation (kTMP) for Chronic Stroke
Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities.
- Trial name
- NCT07681102
- Testing
- kTMP
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Magnetic Tides
Sleep Disorders, Traditional Chinese Medicine Syndrome
Electronic Six-Image Pulse Diagnosis for TCM Syndrome Identification in Sleep Disorders
This is a prospective, single-center, observational diagnostic accuracy study designed to evaluate whether three-dimensional electronic pulse diagnosis can support traditional Chinese medicine syndrome identification in patients…
- Conditions
- Sleep Disorders, Traditional Chinese Medicine Syndrome, Pulse Diagnosis
- Trial name
- SIP-TCM (NCT07695103)
- Testing
- Three-Dimensional Electronic Pulse Diagnosis, Expert Traditional Chinese Medicine Syndrome Differentiation
- Where
- China
- Volunteers
- 201 people
- Sponsor
- Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine
Cardiac Amyloidosis, Left Ventricular Hypertrophy
Detection of Cardiac Amyloidosis Using Right Ventricular Sensing Amplitude in Patients With Left Ventricular Hypertrophy
This multicenter prospective study aims to evaluate the diagnostic performance of right ventricular sensing amplitude measured during cardiac implantable electronic device (CIED) implantation (pacemaker or defibrillator) to…
- Conditions
- Cardiac Amyloidosis, Left Ventricular Hypertrophy, Conduction Abnormality
- Trial name
- DETECT-AMY (NCT07734285)
- Testing
- Cardiac amyloidosis screening during CIED implantation
- Volunteers
- 242 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris