Clinical trials: Amputation
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 2)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04750538
- Testing
- BreEStim 120, BreEStim 240
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- The University of Texas Health Science Center, Houston
Phantom Limb Pain, Phantom Pain
Study of Phantom Limb Pain Using Peripheral Nerve and Spinal Cord Stimulation
The purpose of this study is to evaluate the effectiveness of neuromodulation for relief of phantom limb pain (PLP) using peripheral nerve (PNS) and spinal cord (SCS) stimulation with implantable electrodes.
- Conditions
- Phantom Limb Pain, Phantom Pain, Amputation
- Trial name
- NCT05650931
- Testing
- Implantation of PNS electrodes during surgery, mapping to select sites with the best effect and pain modulation., SCS electrode implantation at surgery, mapping to select sites with the best effect and pain modulation., EEG to search for phantom pain biomarkers
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Artur Biktimirov
Amputation
Transtibial Pin Lock Suspension at Varying Distraction Values Using a Modified Air Bladder Casting System
To assess the effects various distraction values have on the 'slippage' effect of a transtibial pin-lock system
- Trial name
- NCT04248907
- Testing
- 0 pound tension, 2 pound tension, 4 pound tension
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Amputation
Acceptability of an Interim Socket System
This study will explore the acceptability of an interim socket system to new patients with a below-knee amputation and also to NHS healthcare providers.
- Trial name
- ASSIST (NCT05196100)
- Testing
- Amparo confidence socket
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Hull
Amputation
Influence Of A Slope Adaptive Foot On Participation Of Veterans With Lower-Limb Amputations
Veterans with below-knee amputations are limited by prosthetic feet that cannot adapt to sloped and uneven terrain. This limitation results in reduced mobility, reduced balance confidence, and a higher risk of falls among some…
- Trial name
- NCT07266077
- Testing
- Fillauer Slope Adaptive Foot, Fillauer Motion Foot SLX
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Wounded Warrior, Limb Shortening
AMP30: Autologous Fat Grafting, Amputation Sites Pain: Randomized
We propose a prospective, randomized clinical study to assess the efficacy of minimally invasive autologous fat transfer addressing pain and poor prosthetic fit at amputation sites.
- Conditions
- Wounded Warrior, Limb Shortening, Amputation
- Trial name
- AMP30 (NCT02076022)
- Testing
- Enhanced Fat Grafting, Standard fat graft
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- J. Peter Rubin, MD
Pediatric, Neuropathic Pain
Amputations in Childhood and Neuropathic Pain
This observational study aims to assess the presence of neuropathic pain in children and adolescents who underwent limb amputation during childhood.
- Conditions
- Pediatric, Neuropathic Pain, Phantom Limb Pain, Amputation
- Trial name
- NAPE (NCT07401966)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hopitaux de Saint-Maurice
Amputation, Amputation; Postoperative, Sequelae
Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications
This study is a prospective, multi-center, two-arm, unblinded, and randomized controlled trial with a goal of evaluating the impact of a closed incision negative pressure dressing (PREVENA) on incidence of post-operative wound…
- Conditions
- Amputation, Amputation; Postoperative, Sequelae, Wound Dehiscence, Seroma
- Trial name
- PREVENA-AMP (NCT03773575)
- Testing
- PREVENA™ PEEL & PLACE™ Dressing Kit
- Where
- 3 sites in United States, Italy
- Volunteers
- 272 people
- Sponsor
- Thomas Jefferson University
Amputation Stumps
Epidural Calcitonin in Lower Limb Amputation
A prospective randomized double-blind clinical trial design will be used in a cohort of sixty patients of both genders, physical status American Society of Anaesthesiologist (ASA) I and II who will undergo lower limb amputation…
- Trial name
- NCT02115360
- Testing
- Calcitonin, Fentanyl
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Diabetes, PAD
Influence of Diabetes on Lower Limb Amputation
The purpose of this study is to explore the factors that influence limb fitting in those with diabetes compared to those without diabetes.
- Trial name
- NCT02500303
- Where
- United Kingdom
- Volunteers
- 171 people
- Sponsor
- University of Glasgow
Amputation, Traumatic, Pain
Chronic Pain After Amputation
This trial will test the effectiveness of amitriptyline in relieving chronic pain of adults that have had an amputation
- Conditions
- Amputation, Traumatic, Pain, Postoperative Pain
- Trial name
- NCT00006427
- Testing
- Amitriptyline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Amputees
Evaluation of a Multimodal Tactile Feedback System for Upper Limb-loss Users: Embodiment and Performance
The aim of this study is to evaluate the effect of integrating tactile feedback systems into a robotic upper-limb prosthesis. These systems deliver pressure stimuli (through small silicone chambers that inflate), vibration…
- Trial name
- THE_FBHAND (NCT07418645)
- Testing
- Pressure and vibrotactile feedbak, Pressure feedback, Vibrotactile feedback
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- University of Pisa
Cognitive Games, Sports Performance
Development of a Performance Model for Amputee Football Players
This study aims to investigate the effects of a cognitive game-based exercise program on cognitive and physical performance in amputee football players.
- Conditions
- Cognitive Games, Sports Performance, Lower Limb Amputation
- Trial name
- NCT07840781
- Testing
- Gince Intelligence Game-Based Exercise Program, Routine Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Tarsus University
Lower Limb Amputation Below Knee (Injury)
Effects of Prosthesis Training on Pain, Prosthesis Satisfaction and Ambulatory Status of Lower Limb Amputees
The objective of the study is to assess the effects of prosthesis training with and without phantom exercises on pain, prosthesis satisfaction and ambulatory status of lower limb amputees treated with prosthesis training, phantom…
- Trial name
- NCT06013631
- Testing
- Prosthesis Training, Phantom Exercises
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Lahore
Amputation, Traumatic Amputation
Study on the Functionality, Safety and Reliability of a Robotic Prosthesis for the Lower Limb At the Transfemoral Level
The goal of this multicenter interventional pilot is to verify the functionality of a prosthesis for trans-femoral amputees. The main question it aims to answer are: Is to verify the technical functionality, safety and…
- Conditions
- Amputation, Traumatic Amputation, Leg Injury, Lower Limb Injury
- Trial name
- MOTU-ATP (NCT06284005)
- Testing
- WRL ATP
- Where
- Italy
- Volunteers
- 4 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Amputation, Amputation; Traumatic, Hand
Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation
The purpose of this research study is to see how well a new type of myoelectric prosthesis works. A myoelectric prosthesis is a robotic limb for amputees that is controlled by sensing the activity of muscles in the body above the…
- Trial name
- MIRA (NCT05768802)
- Testing
- Myoelectric Implantable Recording Array (MIRA)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Boninger, Michael, MD
Amputation
Forensic-medical Aspects of Lower Limb Prosthetics: An Observational Study
The study investigated the perceived-mobility of patients with unilateral lower limb amputations by means of patient-reported outcome measures (PROMs).
- Trial name
- CP-PRO-01-20 (NCT05392907)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury)
Women's-Specific Footwear With Prosthetic Feet
The purpose of this study is to address footwear challenges unique to women prosthesis users. Comparing the effectiveness of different footwear and prosthesis combinations will help guide clinical decision making regarding the…
- Trial name
- WSF (NCT03673371)
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Amputation, Dysmelia
Physical Activity and Sports for People With Special Needs
Purpose of this study was to assess the balance level of highly qualified amputee football players in relation to their sports level, training experience, position on the pitch, as well as the type of amputation/dysfunction and…
- Conditions
- Amputation, Dysmelia, Leg; Deformity, Congenital
- Trial name
- NCT05778799
- Testing
- Balance test
- Where
- Poland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Transtibial Amputation
Enhancement of Residual Limb Proprioception and Rehabilitation Training Methods With a Vibrotactile Device.
Objectives: The purpose of this study is to investigate attentional (internal vs. external) focus effects on persons with amputation to perform a defined compensatory movement to reduce the likelihood of a fall.
- Trial name
- NCT02026570
- Testing
- Internal Focus of Attention, External Focus of Attention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Southern California Institute for Research and Education