Clinical trials: Amputees
Amputees, Prosthesis User
Effects of Pin and Vacuum Assisted Suspension Systems
This study was performed to determine the presence of any difference between Pin Suspension (PS) and Active Vacuum Suspension (AVS) on walking capacity, functional mobility, weight bearing in the prosthetic side, prosthetic…
- Conditions
- Amputees, Prosthesis User, Artificial Limbs
- Trial name
- NCT04155762
- Testing
- Pin Suspension System (a prosthetic suspension system), Vacuum-Assisted Suspension System (a prosthetic suspension system)
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people
- Sponsor
- Baskent University
Amputees
Traumatic Below-knee Amputees With Prosthetics: Health-related Quality of Life and Locomotor Capabilities
The present study assesses the health-related quality of life and the locomotor capabilities major traumatic lower limb amputees who use prosthesis.
- Trial name
- NCT02439463
- Testing
- Below-knee amputation
- Where
- Finland
- Volunteers
- 26 people
- Sponsor
- Helsinki University Central Hospital
Amputation, Prosthesis User
Biomechanical Study of Different Prostheses for Unilateral Transtibial Amputees During Indoor and Outdoor Activities
The goal of this observational study is to evaluate and compare the performance of two prosthetic feet for unilateral transtibial amputees during both indoor and outdoor activities.
- Trial name
- NCT06390033
- Testing
- Prosthetic foot
- Where
- Hong Kong
- Volunteers
- 6 people
- Sponsor
- The Hong Kong Polytechnic University
Lower Limb Amputation
Outcome Measures for Lower Limb Amputees - A Repeatability Study
During any period of rehabilitation it is important to select meaningful tests that; measure what you want, are responsive to changes in the patient's condition and, easy to use in the clinical settings.
- Trial name
- NCT01953939
- Testing
- Prosthetic Limb Users
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Queen Margaret University
Trauma Injury, Trauma Blunt
Extremity Trauma At a Level 1 Trauma Center
Blunt vascular trauma to the lower extremity has been associated with injuries to the anteroposterior tibial arteries or popliteal artery in the form of transection, occlusion, or intimal injury.
- Conditions
- Trauma Injury, Trauma Blunt, Vascular Trauma
- Trial name
- NCT06402669
- Testing
- Packed Red Blood Cell Administration
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Arrowhead Regional Medical Center
Amputation
Massage on Pain Levels, Range of Motion, and Muscle Strength in Unilateral Lower Limb Amputees
The purpose of this graduate research study is to explore the therapeutic benefits of Myofascial Release massage on lower limb amputees with pain levels, range of motion, and muscle strength.
- Trial name
- NCT03389334
- Testing
- massage
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Lower Limb Amputation Above Knee (Injury)
Assessment of the Prosthetic System Impact on Mental Workload in Above-knee Lower Limb Amputees.
New generation of lower limb prosthesis provide improved functionalities. They are usually studied in the scope of biomechanics, sometimes PROMs like quality of life.
- Trial name
- INCREMENT (NCT06635655)
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Proteor Group
Amputations, Traumatic
Gait Evaluation of Experienced Below Knee Amputees
Post traumatic amputees with an experience of over 3 months of prosthesis use at home, without any known difficulty using the prosthesis and without stump pathology, using no assistive devices, will be examined in a 3 D…
- Trial name
- NCT00353626
- Where
- Israel
- Volunteers
- 9 people
- Sponsor
- Sheba Medical Center
Critical Limb Ischemia
Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients.
This study will evaluate the efficacy and safety of apixaban 2.5 mg twice daily plus aspirin compared to the standard treatment (clopidogrel plus aspirin) in patients with critical limb ischemia undergoing infrapopliteal arterial…
- Trial name
- AGRIPPA (NCT04229264)
- Testing
- Apixaban, ASA, Clopidogrel 75mg
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Science Valley Research Institute
Neuroma Amputation
Evaluation of Ultrasonic Neuroma Size With Residual Limb Pain in Above-Knee Amputees
Background: The formation of neuromas, a fusiform swelling of a nerve or nerve ending, is a well documented response to limb amputation.
- Trial name
- NCT00686764
- Testing
- Observational
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Amputation Arm and Hand, Unilateral Right, Amputation Arm and Hand, Unilateral Left
Neural Enabled Prosthesis for Upper Limb Amputees
This study is designed to evaluate the feasibility of The Adaptive Neural Systems Neural-Enabled Prosthetic Hand (ANS-NEPH) system.
- Conditions
- Amputation Arm and Hand, Unilateral Right, Amputation Arm and Hand, Unilateral Left, Prosthesis User
- Trial name
- NCT03432325
- Testing
- Neural Enabled Prosthesis
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of Arkansas, Fayetteville
Traumatic Amputation of Lower Extremity
Prosthetic Fit Assessment in Transtibial Amputees Secondary to Trauma
The aims of this study address an exploratory endpoint in the Major Extremity Trauma Research Consortium (METRC) Transtibial Amputation Outcomes Study (TAOS; NCT01821976) that is investigating prosthesis fit, alignment and…
- Trial name
- ProFit (NCT02540681)
- Where
- 10 sites in United States
- Volunteers
- 33 people
- Sponsor
- Major Extremity Trauma Research Consortium
Amputation
The Effect of Different Microprocessor Knee Prostheses on Mobility and Gait Parameters in Transfemoral Amputees
Microprocessor knee joints are prosthetic knee joints with an integrated processor or a computer that can analyze data. During walking, parameters such as step speed, joint angles, and weight transferred through sensors are…
- Trial name
- NCT04966936
- Testing
- questionnaires for clinical assessments, 2 minute walking test, The gait analysis at the motion analysis laboratory.
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Transfemoral Amputation, Limb Loss
Effect of a Microprocessor-controlled Prosthetic Knee Joint on K2 Level Ambulators
Microprocessor-controlled knees (MPKs) automatically adjust resistance or damping in the joint to improve swing- and/or stance-phase control as appropriate for the prosthesis user during gait.
- Conditions
- Transfemoral Amputation, Limb Loss, Limb Absence
- Trial name
- MPK-K2 (NCT07103798)
- Testing
- College Park ICON, Conventional NMPK
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Somatosensory Perception Following Lower Limb Amputation
Spinal Cord Stimulation (SCS) for Amputees
The purpose of this study is to investigate how leg amputee patients can feel sensations with neuromodulation while they are using a prosthetic leg.
- Trial name
- NCT04490382
- Testing
- 32 channel external stimulator
- Sponsor
- Duke University
Amputee
Investigation of Physical Activity and Associated Factors in Lower Extremity Amputees
The aim of this study was to investigate the physical activity and related factors of individuals with lower extremity amputation.
- Trial name
- NCT03825432
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Eastern Mediterranean University
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Spinal Cord Stimulation for Restoration of Function in Lower-Limb Amputees, 90-Day
The goals of this study are to provide sensory information to amputees and reduce phantom limb pain via electrical stimulation of the lumbar spinal cord and spinal nerves.
- Trial name
- SCS-90 (NCT04547582)
- Testing
- Spinal cord stimulator
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Lee Fisher, PhD
Amputation
A Unique Body-Powered Terminal Device With Enhanced Grasping Capabilities for Individuals With Upper Limb Loss
We have developed a novel terminal device for a prosthetic arm that eliminates the functional tradeoffs seen in body-powered voluntary open devices.
- Trial name
- NCT07254247
- Testing
- Novel Prosthetic Hook, Control Hook (Light Spring), Control Hook (Heavy Spring)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Little Room Innovations, LLC
Amputation, Transfemoral Amputation
Investigation on a New Power Knee Firmware Update on Gait and Daily Life Activities for Transfemoral Amputees
The goal of this interventional study is to investigate a new firmware in development for Power Knee on gait and daily life activities in unilateral transfemoral amputees.
- Trial name
- NCT06620861
- Testing
- Power Knee Firmware Update, Power Knee Current Marketed Firmware
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Össur Iceland ehf
Lower Limb Amputation Below Knee (Injury)
Human-Prosthetic Interaction: Brain & Technology After Lower-Limb Loss
This study evaluates brain neuroplasticity and functional performance in people with unilateral lower limb amputation.
- Trial name
- HumanIT (NCT05818410)
- Testing
- Prosthetic device (Lunaris), No prosthetic device, Prosthetic device (Sach foot)
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel