Clinical trials: Anaesthesia, Spinal
Gall Stone Disease, Polyp
Comparison of Coagulation Factors During Laparoscopic Cholecystectomy
Pneumoperitoneum is formed with CO2 during laparoscopic abdominal operations. Effect of pneumoperitoneum on coagulation factors is not well known.
- Trial name
- NCT02568852
- Testing
- Combined anaesthesia, General anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Sensation Diminished, Pinprick
A Device to Determine Return of Sensation From Spinal Block
Participation in this study will involve having a pad wrapped onto the subject's non-surgical leg to detect when sensation returns after spinal anesthetic and while in recovery room.
- Trial name
- NCT04553913
- Testing
- cooling device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Wake Forest University Health Sciences
Total Hip Arthroplasty
Spinal Anesthesia in Total Hip Arthroplasty
Spinal anesthesia is commonly used in patients undergoing total hip replacements. The purpose of this study is to compare lidocaine to bupivacaine spinal anesthesia in patients having a total hip arthroplasty (THA).
- Trial name
- NCT02818894
- Testing
- Lidocaine, Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- Thomas L Bradbury
Inguinal Hernia
Comparing Non-fixation of Mesh to Mesh Fixation in Laparoscopic Inguinal Hernia Repair
The purpose of the study is 1. To compare the recurrence rate of the laparoscopic total extra peritoneal inguinal hernia repair without fixation of the mesh to mesh fixation under spinal anesthesia 2.
- Trial name
- NCT01117337
- Testing
- Mesh Fixation
- Where
- India
- Volunteers
- 104 people
- Sponsor
- Moulana Hospital
Hypothermia
Pre-warming Prevents Hypothermia in Elective Cesarean Section
Background: Hypothermia is common during general and regional anesthesia even when active warming measures are taken. The existing literature shows that, in pregnant patients, the use of forced air-warming during cesarean section…
- Trial name
- hypothermia (NCT02091466)
- Testing
- pre-warming
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Pain
Effect of Gabapentin Enacarbil on Opioid Consumption and Pain Scores
Opioids are effective analgesics, but cause side effects including sedation, respiratory depression, low blood pressure, nausea, and constipation.
- Trial name
- NCT02840240
- Testing
- Gabapentin enacarbil
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- The Cleveland Clinic
Patients Aged 55 or Older, BMI More Than 40 kg/m2
A Real-Time Ultrasound Guided Approach For Spinal Anesthesia
Our goal was to compare the number of attempts to perform spinal anesthesia using real-time ultrasound guidance versus landmark technique in patients meeting predefined criteria for difficult spinal anesthesia.
- Conditions
- Patients Aged 55 or Older, BMI More Than 40 kg/m2, Scoliosis
- Trial name
- NCT01570491
- Testing
- ultrasound-guided spinal anesthesia, standard spinal anesthesia
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- The Cleveland Clinic
Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural
Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?
Aim of this study is to determine whether Inferior Vena Cava analyzed by trans-thoracic echocardiography is an effective method to guide titrated fluid repletion in non critical patients, in order both to decrease post procedural…
- Conditions
- Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural, Regional Anesthesia Morbidity
- Trial name
- NCT02271477
- Testing
- Ultrasound-guided volemic repletion
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Arthroplasty, Replacement, Knee
Music Therapy Versus Control for Total Knee Arthroplasty
For millennia, people have listened to and enjoyed music for entertainment, as a distraction from daily troubles, and as a means to relax and relieve stress.
- Trial name
- NCT03569397
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Alabama at Birmingham
Postoperative Complications, Hip Fracture
A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia
This pilot project will address the gaps in knowledge regarding the effect of anesthetic technique on the risk of delirium through an adequately-powered trial employing standardized regimens for treatment and outcome assessment…
- Conditions
- Postoperative Complications, Hip Fracture, Delirium
- Trial name
- NCT02190903
- Testing
- General endotracheal anesthesia, Regional (spinal) Anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Pennsylvania
Lumbar Spine Injury
The Use of Dantrolene to Improve Analgesia in Posterior Lumbar Surgery
The purpose of this study is to determine whether administration of a non-centrally acting muscle relaxants will improve the Overall Benefit of Analgesia Score (OBAS), and Richmond Agitation Sedation Scale (RASS) scores in…
- Trial name
- NCT03762109
- Testing
- Dantrolene
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy, Pain
Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study
Pain relief after cesarean delivery can be provided in a few ways. Most commonly, certain medications called opioids, such as morphine, are given through the vein or into the muscle.
- Conditions
- Healthy, Pain, Pregnancy
- Trial name
- NCT01943565
- Testing
- Hydromorphone 25mcg, Hydromorphone 50mcg, Hydromorphone 100mcg
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Infants Undergoing Surgery
Changes in Tissue and Cerebral Oxygenation Following Spinal Anesthesia in Neonates, Infants, and Children
Investigators have started an awake spinal anesthesia program in conjunction with pediatric surgical colleagues. Patients are offered the option of awake spinal anesthesia instead of general anesthesia for appropriate surgical…
- Trial name
- NCT02840253
- Testing
- NIRS
- Volunteers
- 23 people
- Sponsor
- Joseph D. Tobias
Pregnancy, Pain
VerTouch Device: A Prospective Randomized Controlled Trial
This study will compare the VerTouch device to palpation and ultrasound (US) techniques used to identifying the anatomic landmarks and optimal location for neuraxial access.
- Trial name
- NCT04630171
- Testing
- Group #1: VerTouch utilized for identification of site for labor epidural or spinal anesthesia procedure, Group #2: Ultrasound (US) utilized for identification of site for labor epidural or spinal anesthesia procedure, Group #3: Control group, palpation utilized for identification of site for labor epidural or spinal anesthesia procedure
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Northwestern University
Hypotension
Spinal Anesthesia Induced Hypotension During Cesarean Section
The purpose of this study is to compare two methods for preventing low blood pressure associated with spinal anesthesia during Cesarean sections.
- Trial name
- NCT00846651
- Testing
- Colloid administration, Crystalloid administration, phenylephrine infusion
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Milton S. Hershey Medical Center
Hematologic Diseases, Neoplasms
A Dose Finding Study of Remifentanil and Propofol for Lumbar Punctures in Children
This study will examine whether the combination of two anaesthetic medications, propofol and remifentanil, is suitable for short duration surgical procedures, providing a shorter recovery time and fewer side effects than either…
- Trial name
- NCT00213239
- Testing
- Remifentanil
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- The Hospital for Sick Children
External Cephalic Version
Success of External Cephalic Version Study
The purpose of this study is to determine the best way to optimize the success of external cephalic version (turning the baby from the outside).
- Trial name
- NCT03106753
- Testing
- Bupivacaine, Terbutaline
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Spinal Anesthesia, Cesarean Section
Does the Addition of Epinephrine Prolong the Duration of Spinal Anesthesia for Repeat Cesarean Section?
The purpose of this study is to investigate whether the addition of a medication called epinephrine to spinal medications prolongs the duration of the anesthesia.
- Trial name
- NCT02369510
- Testing
- Low-dose epinephrine, High-dose epinephrine, No epinephrine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cognitive Dysfunction
Effect of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction
This study will aim to identify the impact of Intraoperative dexmedetomidine infusion on POCD assessed by the Montreal Cognitive Assessment (MoCA) in geriatric patients above 60 years undergoing hip surgery under spinal…
- Trial name
- NCT03793751
- Testing
- Dexmedetomidine Injection
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Tata Main Hospital
Effects of; Anesthesia, in Labor and Delivery
Phenylephrine vs. Norepinephrine Infusion After Spinal Anesthesia for Cesarean Delivery
The purpose of the study is to determine if a medication called phenylephrine, which helps to control blood pressure, is more effective as a continuous intravenous (IV) infusion compared to continuous IV norepinephrine in…
- Trial name
- NCT02354833
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- West Virginia University