Clinical trials: Anaesthesia and Analgesia
General Anesthetic Drug Overdose, Adverse Effect of Intravenous Anesthetics, Sequela
Fully Automated Anesthesia, Analgesia and Fluid Management
Evaluate the feasibility and quality of automated anesthesia, analgesia and fluid management based on a combination of several physiological variables (bispectral index [BIS], stroke volume [SV], and stroke volume variation…
- Conditions
- General Anesthetic Drug Overdose, Adverse Effect of Intravenous Anesthetics, Sequela, Complication of Anesthesia, Drug Delivery System Malfunction
- Trial name
- NCT02886806
- Testing
- BIS XP, Covidien, Ireland, EV-1000 TM, Edwards Lifesciences, Irvine, California, USA
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- Erasme University Hospital
Postoperative Pain, Analgesia
Postoperative Analgesis for Pain Management After Thoracotomy
Thoracotomy is among the most painful surgical procedures and can cause severe pain. Postoperative pain causes many complications. Therefore, pain management is important in patients undergoing thoracotomy.
- Trial name
- NCT06177652
- Testing
- Paravertebral Block, Serratus Plane Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Kocaeli University
Pain, Actinic Keratosis
Pain Management During a Photodynamic Therapy Session on the Vertex for Actinic Keratosis: Tumescent Anesthesia Interest
This study focus on the efficacity of tumescent anesthesia in pain management during a photodynamic therapy on the vertex for treatment of actinic keratosis.
- Conditions
- Pain, Actinic Keratosis, Analgesia, Phototerapy
- Trial name
- ANTUKA (NCT04779255)
- Testing
- Procedure (Tumesent anesthesia), Control Arm (Paracetamol)
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Poitiers University Hospital
Breast Cancer, Pain, Acute
ESP in Breast Surgery Due to Cancer
Patients scheduled for breast surgery due to cancer. Each patient will be treated with intravenous (i.v.) oxycodone - patient-controlled analgesia (PCA).
- Conditions
- Breast Cancer, Pain, Acute, Anesthesia, Local
- Trial name
- NCT04726878
- Testing
- Erector spinae plane block, General anesthesia, Patient-controlled analgesia
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Medical University of Lublin
Cholecystectomy, Postoperative Pain
Erector Spinae Plane Block Versus External Oblique Intercostal Plane Block for Analgesia in Open Cholecystectomy
This randomized controlled trial aims to compare the analgesic efficacy of bilateral ultrasound-guided erector spinae plane block (ESPB) versus bilateral external oblique intercostal plane (EOI) block in patients undergoing open…
- Conditions
- Cholecystectomy, Postoperative Pain, Erector Spinae Plane Block, Regional Anesthesia
- Trial name
- NCT07533279
- Testing
- Erector Spinae Plane Block, External Oblique Intercostal Plane Block
- Volunteers
- 66 people
- Sponsor
- Sohag University
Dental Anxiety, Dental Pain
Comfort-in Needle-Free Injection System in Pediatric Dental Anesthesia
This randomized split-mouth clinical trial evaluated the efficacy of the Comfort-in needle-free injection system compared with conventional dental injection for local anesthesia during pulpotomy treatment in children.
- Conditions
- Dental Anxiety, Dental Pain, Pulpotomy, Local Anesthesia
- Trial name
- NCT07585812
- Testing
- Comfort-in Needle-Free Injection System, Conventional Dental Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Pain
Goal-directed Analgesia Using ANI During General Anesthesia in Children With Moyamoya Disease
Analgesia Nociception Index (ANI) has been proposed for the evaluation of the nociception-antinociception balance in the perioperative period.
- Trial name
- NCT05672212
- Testing
- ANI (Analgesia/Nociception Index) monitoring, standard monitoring, Sufentanil
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Conscious Sedation Failure During Procedure, Analgesia
Lidocaine as Local Anesthetics in Children Under Ketamine Sedation
Ketamine seems an obvious choice in the setting of an emergency department in laceration repair. Lidocaine is the local anesthetics widespread used. Ketamine leads to dissociative amnesia.
- Conditions
- Conscious Sedation Failure During Procedure, Analgesia, Anesthesia
- Trial name
- NCT02205502
- Testing
- Lidocaine, Normal saline
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Upper Extremity Injury
Clinical Evaluation of the Ultrasound-Guided Retroclavicular Brachial Plexus Block
The primary objective of this prospective, descriptive study is to evaluate the success rate of the retroclavicular brachial plexus block and catheter placement in 60 adult patients undergoing hand, wrist, or forearm surgery.
- Trial name
- NCT01605929
- Testing
- Retroclavicular Brachial Plexus Block and Catheter Insertion
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Postoperative Pain
The Analgesic Efficacy of Bilateral Erector Spinae Plane Block in Comparison With Intrathecal Morphine After Elective Cesarean Section
The aim of this study was to assess the analgesic efficacy of bilateral erector spinae plane block in comparison with intrathecal morphine after elective cesarean section under spinal anesthesia.
- Trial name
- NCT03935412
- Testing
- Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Labor Pain and to Reduce Pain
Does the Volume of Medication Affect the Success of Labor Epidural Analgesia
The purpose of this study is to evaluate whether changing the volume and concentration of a medication affects the quality of pain relief and the side effects associated with labor epidural analgesia.
- Trial name
- EpiVol (NCT07684365)
- Testing
- administration of bupivacaine 7.5 mg and fentanyl 24 mcg every 40 minutes
- Volunteers
- 70 people
- Sponsor
- Beth Israel Deaconess Medical Center
Anxiety, Pain
Music Use in Parturients Admitted to Labor & Delivery
The goal of this clinical trial is to learn if music use affects anxiety or pain levels in parturients admitted to labor and delivery. It will also learn about the effect of music use on patient satisfaction.
- Conditions
- Anxiety, Pain, Patient Satisfaction
- Trial name
- NCT06969105
- Testing
- Music
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Healthy
Dexamethasone Intravenous Versus Intrathecal in Spinal Anesthesia
The purpose of this study is to compare the the effect of intravenous and the intrathecal dexamethasone when added to spinal anesthesia in cesarean section.
- Trial name
- NCT05470530
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative
Comaprison Between QLB and ESPB in Patients for PCNL Operation
comparing the subcostal oblique Quadratus Lumborum block and the Erector Spinae plane block in patients undergoing percutaneous nephrolithotomy operation to get the best and longest postoperative analgesic effect.
- Trial name
- NCT04277611
- Testing
- Subcostal Oblique Quadratus Lumborum Block and Erector Spinae Plain Block.
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain
Comparison of Analgesic Efficacy of Fentanyl, Sufentanil and Butorphanol After Remifentanil Anesthesia
Fast awakening from anesthesia is one of the major characteristics of remifentanil-associated anesthetic induction and maintenance, whereas corresponding pain during awakening influences patient's rehabilitation strongly.
- Trial name
- CARAN (NCT00738192)
- Testing
- Fentanyl citrate, Sufentanil citrate, Butorphanol tartrate
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Nanjing Medical University
Anesthesia
Impact of Dexamethasone Added to Intra-articular Morphine and Bupivacaine for Post-operative Analgesia After Knee Arthroscopy
A randomized double-blinded clinical trial was carried out on 40 patients undergoing knee arthroscopy. Patients were divided randomly into two equal groups.
- Trial name
- NCT04790292
- Testing
- group M, group MD
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Postoperative Pain
Effectiveness of TAP Block Versus Intravenous Analgesia in Postoperative Pain Management Following Gynecologic Laparoscopic Surgery
Optimal postoperative pain control is crucial in laparoscopic gynecologic surgery, particularly within Enhanced Recovery After Surgery (ERAS) protocols.
- Trial name
- NCT07051499
- Testing
- TAP Block Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Foggia
Cleft Lip, Cleft Palate +/- Lip
Comparative Study of Regional Nerve Blocks in Primary Cleft Palate Repair
This study will evaluate whether adding a suprazygomatic maxillary nerve block to the standard palatal nerve block improves pain control after cleft palate repair surgery in children.
- Conditions
- Cleft Lip, Cleft Palate +/- Lip, Pain Management, Wound Dehiscence, Surgical
- Trial name
- NCT07892963
- Testing
- Palatal Nerve Block, Suprazygomatic Maxillary Nerve Block
- Volunteers
- 144 people
- Sponsor
- Children's National Research Institute
Gastric Cancer
Analgesia Nociception Index-guided Anesthesia and Standard Anesthesia
The primary purpose of this study is to compare the analgesia nociception index-guided anesthesia and standard anesthesia on remifentanil requirement in desflurane anesthesia.
- Trial name
- NCT06123637
- Testing
- Analgesia nociception index-guided anesthesia, Standard anesthesia
- Volunteers
- 68 people
- Sponsor
- Ajou University School of Medicine
Colorectal Cancer
Xenon Combined With Intraoperative Thoracic Epidural Analgesia
This is a monocentric study in 2 steps: A safety part to assess the feasibility of using Xenon in association with a thoracic epidural analgesia (TEA) with a sequential recruitment of 3, 6 or 9 patients according to predefined…
- Trial name
- NCT01696630
- Testing
- Xenon, Desflurane
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Centre Leon Berard
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