Clinical trials: Anaesthesia and Analgesia
Brachial Plexus Anesthesia, Analgesia
Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia
Adding dexamethasone to local anesthetic will significantly prolong duration of brachial plexus anesthesia and analgesia.
- Trial name
- NCT01739270
- Testing
- supraclavicular brachial plexus block
- Where
- Croatia
- Volunteers
- 55 people
- Sponsor
- University Hospital Dubrava
Ventral Hernia, Postoperative Pain
Evaluation of Ultrasound-guided Erector Spinae Block for Postoperative Analgesia in Laprascopic Ventral Hernia Repair.
Ventral hernia repair is associated with significant postoperative pain, and regional anesthetic techniques are of potential benefit.
- Conditions
- Ventral Hernia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT04438369
- Testing
- Erector Spinae Plane Block
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Ostfold Hospital Trust
Analgesia, Anesthesia
Comparison of Paravertebral Block and Subcostal Transversus Abdominis Plane Block in Laparoscopic Nephrectomy
Most of the patients undergoing laparoscopic partial/radical nephrectomy can experience moderate or severe postoperative pain, and inadequate control of this pain can cause negative consequences such as development of chronic…
- Conditions
- Analgesia, Anesthesia, Pain, Postoperative
- Trial name
- NCT05723341
- Testing
- Bupivacain, Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Istanbul University
Acute Postoperative Pain, Lower Limb Surgery
Tapentadol vs Pregabalin for Postoperative Pain in Lower Limb Surgery
This pilot randomised controlled trial compared 72-hour oral premedication with tapentadol (50 mg every 12 hours) versus pregabalin (75 mg every 24 hours) for preventing acute postoperative pain in 46 patients undergoing elective…
- Trial name
- NCT07587645
- Testing
- Tapentadol, Pregabalin
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- ISSSTE Hospital Regional "Gral. Ignacio Zaragoza"
Lung Neoplasms, Postoperative Pain
Prospective Randomized Trial Comparing the Effectiveness of Continuous Paravertebral Infusion of Local Anesthetics Versus Intravenous Patient-controlled Analgesia on Acute and Chronic Neuropathic Pain After VATS Lobectomy
Since mid-2000, thoracoscopic lobectomy has been replaced with conventional open lobectomy and it has reduced the operative morbidities and mortalities.
- Trial name
- NCT01703351
- Testing
- 0.5% ropivacaine, Fentanyl 500mcg + acupan 160mg + nasea 0.6mg
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Yonsei University
Pelvic Bone Injury, Pelvis Injury
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.
The goal of this observational clinical trial is to assess the impact of Regional Anesthesia (RA) techniques with the strongest anatomical and scientific support in controlling acute post-operative pain in pelvic/acetabular…
- Conditions
- Pelvic Bone Injury, Pelvis Injury, Acetabular Fractures, Acetabular Surgery
- Trial name
- RELIEVED (NCT07072286)
- Testing
- Regional Anesthesia, Multimodal analgesia
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Balanced Anesthesia
Surgical Pleth Index (SPI) Guided Analgesia During Sevoflurane Anesthesia
The aim of the present study was to compare SPI guided analgesia with standard clinical practise during general anesthesia using a balanced setting of sevoflurane and sufentanil anesthesia.
- Trial name
- NCT01525537
- Testing
- administration of sufentanil, sufentanil
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University Hospital Schleswig-Holstein
Mastectomy; Lymphedema, Local Infiltration
A Comparison of Local Infiltration Analgesia and Pecs Block for Analgesia in Mastectomy With Axillary Dissection - an Equivalence Study
The investigators aim to compare the quality of pain relief provided by local infiltration analgesia delivered by surgeon and Pecs block delivered by anaesthetist under ultrasound guidance for patients undergoing mastectomy with…
- Conditions
- Mastectomy; Lymphedema, Local Infiltration, Anesthesia, Local, Block
- Trial name
- NCT03602794
- Testing
- PECs Block, Local infiltration
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Louis Ng Xiang Long
Pericardial Effusion, Inflammatory Response After Surgery
Anesthesia Management, Inflammatory Response and Recovery After Non-intubated VATS Pericardial Window
Non-intubated video-assisted thoracoscopic surgery (NIVATS) is performed under spontaneous ventilation and avoids tracheal intubation and one-lung mechanical ventilation.
- Conditions
- Pericardial Effusion, Inflammatory Response After Surgery, Postoperative Complications, Procedural Sedation and Analgesia
- Trial name
- RNIVATS (NCT07800767)
- Testing
- Systemic opioid-based analgesia during NIVATS, Thoracic regional analgesia during NIVATS
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Pain
SFIB vs Anterior QLB in Total Hip Arthroplasty
Quadratus lumborum block (QLB) is a facial plane block defined to provide analgesia from T7-L3 dermatomes. There are articles reporting that it is an effective analgesic method in hip surgeries.
- Trial name
- NCT05684471
- Testing
- Ultrasound Guided Suprainguinal Fascia iliaca Block, Ultrasound Guided Anterior Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Samsun University
Pregnancy
Intrathecal Clonidine in Cesarean Section May Lead to Worse Blood Gas Results in the Newborns
The purpose of this study is to evaluate effects of intravenous clonidine in acute and chronic post-cesarean pain, possible adverse effects over mother-newborn pair, in comparison to intrathecal adjuvant clonidine and placebo.
- Trial name
- NCT02550444
- Testing
- Intrathecal Clonidine, Intravenous Clonidine
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Pain, Acute Post-Operative, Ambulatory Surgical Procedures
Machine Learning-Based Prediction of Postoperative Pain After Pediatric Ambulatory Surgery
This study aims to predict pain after surgery in children of ages 1 to 3 years by using computer programming (machine learning). Participant children will be observed before, during, and after surgery.
- Conditions
- Pain, Acute Post-Operative, Ambulatory Surgical Procedures, Pediatric Pain, Pediatric Patient (1m-21y)
- Trial name
- NCT07274995
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Thoracic Epidural Analgesia, Gastric Cancer
General Anesthesia and General Anesthesia Combined With Thoracic Epidural Anesthesia
This randomized controlled trial investigated whether adding thoracic epidural analgesia to general anesthesia affects intraoperative neuromuscular blockade and opioid requirements in patients undergoing gastric cancer surgery.
- Trial name
- NCT05907811
- Testing
- Neuromuscular blocker usage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Elective Total or Subtotal Abdominal Hysterectomy
Intraoperative Lidocaine Infusion for Analgesia (ILIA)
The purpose of this study is to evaluate the efficacy of intravenous lidocaine infusion administered during general anesthesia in: 1. Reducing length of hospital stay following total abdominal hysterectomy 2.
- Trial name
- NCT00382499
- Testing
- Lidocaine Intravenous Infusion
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- University of Ottawa
Pain, Postoperative
Comaprison Between QLB and ESPB in Patients for PCNL Operation
comparing the subcostal oblique Quadratus Lumborum block and the Erector Spinae plane block in patients undergoing percutaneous nephrolithotomy operation to get the best and longest postoperative analgesic effect.
- Trial name
- NCT04277611
- Testing
- Subcostal Oblique Quadratus Lumborum Block and Erector Spinae Plain Block.
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Post Operative Pain, Motor Activity
Compartive Study Between Caudal and Perianal Block During Anal Sphincter Sparing Procedures Under General Anesthesia
Anal fistula is an abnormal tract communicating an external opening in the perianal skin with an internal opening in the anal canal. Anal fistula is treated by fistulotomy .
- Trial name
- NCT05557734
- Testing
- caudal block, perianal block
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Arthropathy of Hip
Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty
The goal of this retrospective chart review is to evaluate if the implementation of lumbar plexus block placement for postoperative pain have improved conditions in the postoperative period for patients undergoing total hip…
- Trial name
- NCT02493621
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Post-operative Delirium, Cognitive Dysfunction
Effect of Epidural Analgesia on Burst Suppression
It has been shown in previous studies that burst suppression has an effect on the development of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD).
- Conditions
- Post-operative Delirium, Cognitive Dysfunction, Electroencephalography
- Trial name
- NCT05688449
- Testing
- Bupivacaine-fentanyl, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bezmialem Vakif University
Anterior Cruciate Ligament Injury
Effect of Adding Vastus Medialis Nerve Block to Adductor Canal Block After Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) reconstruction is frequently associated with moderate to severe postoperative pain, which can delay mobilization and rehabilitation.
- Trial name
- VAMA (NCT07683078)
- Testing
- Adductor Canal Block (ACB) Only, Vastus Medialis Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Postoperative Pain
Transversus Abdominis Plane Blocks for Infants and Children for Postoperative Pain Control
After undergoing hernia surgery, hydrocelectomy or lower abdominal surgery, a child may experience some amount of pain in the post-operative period.
- Trial name
- NCT01559740
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
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