Clinical trials: Anaesthesia and Analgesia
Cesarean Delivery, Postoperative Analgesia
Intrathecal Morphine vs Transversalis Fascia Plane Block After Cesarean Delivery
This prospective single-center study compares intrathecal morphine and ultrasound-guided bilateral transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean delivery under spinal…
- Conditions
- Cesarean Delivery, Postoperative Analgesia, Obstetric Anesthesia
- Trial name
- NCT07374133
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women in spontaneous labor with whom analgesia is maintained with a combined spinal epidural (CSE)…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982838
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pain, Postoperative
Transversus Abdominis Plane Block and Quadratus Lumborum Block in Pediatric Patients
In the pediatric age group, postoperative pain is very important for the children to have a comfortable and problem-free postoperative period.
- Trial name
- NCT04209478
- Testing
- Tramadol hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Anesthesia
Influence of Intraoperative Analgesia on the Postoperative Morphine Consumption
Unlike longer acting opiates (sufentanil), remifentanil may provoke postoperative hyperalgesia. We have developed two automated bispectral index - guided drug delivery systems: one for propofol administration, the other for…
- Trial name
- NCT00772616
- Testing
- Remifentanil, Sufentanil
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hopital Foch
Postoperative Pain, Shoulder Arthroscopy
SPENG Block Versus Suprascapular and Axillary Nerve Blocks for Pain After Shoulder Arthroscopy
This prospective, randomized, patient- and assessor-blinded, single-center non-inferiority trial will compare the analgesic efficacy of the Shoulder Posterior Pericapsular Nerve Group (SPENG) block with combined posterior…
- Trial name
- SPENG-RCT (NCT07762417)
- Testing
- Shoulder Posterior Pericapsular Nerve Group (SPENG) Block, Combined Posterior Suprascapular and Axillary Nerve Blocks
- Volunteers
- 60 people
- Sponsor
- Izmir City Hospital
Postoperative Pain
Transversalis Fascia Plane Block Versus Low-Dose Intrathecal Morphine for Open Inguinal Hernia Repair
Open inguinal hernia repair is commonly associated with early postoperative pain, which may delay mobilization, reduce patient satisfaction, and increase opioid consumption.
- Trial name
- NCT07695935
- Testing
- Intrathecal morphine, Ultrasound-guided transversalis fascia plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Pain After the Surgical Extraction of Third Molars
The Effects of Tramadol Combined With Local Anesthesia on Pain After the Surgical Extraction of Third Molars
The purpose of this study was to assess the efficacy of local anesthetic and tramadol combinations in the prevention of pain after the surgical extraction of third molars.
- Trial name
- NCT05614440
- Testing
- Local anesthetic + tramadol hydrochloride, Only local anesthetic
- Volunteers
- 60 people
- Sponsor
- Marmara University
Robotic Surgical Procedures, Pneumonectomy; Status
Robot-assisted Lobectomy Versus Video-assisted Lobectomy
This prospective and observational cohort studies the morphine consumption difference during the first 48 hours after a lung lobectomy between patients operated with a robot assisted or a video-assisted technique for a lung…
- Conditions
- Robotic Surgical Procedures, Pneumonectomy; Status, Anesthesia and Analgesia, Cardiac Output
- Trial name
- NCT03111797
- Testing
- Morphine, Cardiac output measure
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Hospital Nord
Postoperative Pain
ESP vs QL for Total Abdominal Hysterectomy
Patients undergoing open total abdominal hysterectomy (n=82) at Parkland Memorial Hospital will be randomized into one of two groups to receive either ultrasound-guided bilateral ESP block with liposomal bupivacaine (Group 1) or…
- Trial name
- NCT04074226
- Testing
- Erector Spinae Plane block, Quadratus Lumborum Block
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Modified Radical Mastectomy, Post Operative Pain, Acute
Comparıson of Analgesıc Effıcacy of Dıfferent Volumes of Serratus Posterior Superıor Intercostal Plane Block After Modıfıed Radıcal Mastectomy Surgery
The aim of researchers is to compare the effects of three different local anesthetic concentrations and volumes on opioid consumption, postoperative analgesic efficacy, and pain scores during ultrasound-guided SPSIP blocks in…
- Conditions
- Modified Radical Mastectomy, Post Operative Pain, Acute, Facial Plane Blocks
- Trial name
- NCT07670078
- Testing
- Serratus Posterior Superior Intercostal Plane (SPSIP) block 40 ml of 0.1875% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 50 ml of 0.15% bupivacaine, Serratus Posterior Superior Intercostal Plane (SPSIP) 30 ml of 0.25% bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cumhuriyet University
Tympanomastoid Surgery, Cochlear Implant
Great Auricular Nerve Block for Children Undergoing Tympanomastoid Surgery
The investigators goal is to determine the efficacy and duration of analgesia with the addition of Clonidine, an alpha-2 agonist, to local anesthetic blockade using bupivacaine, of the great auricular nerve in children undergoing…
- Conditions
- Tympanomastoid Surgery, Cochlear Implant, Mastoidectomy, Cholesteatoma
- Trial name
- NCT01638052
- Testing
- 0.25% Bupivacaine + Clonidine
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Anesthesia, Catheter Blockage
The Efficacy of Continuous Femoral Nerve Catheter Orifice Configuration for Postoperative Analgesia in Knee Arthroplasty
Femoral nerve catheter for postoperative analgesia will be included in the adult patients undergoing total knee arthroplasty included in the study.
- Conditions
- Anesthesia, Catheter Blockage, Knee Arthropathy, Pain, Postoperative
- Trial name
- NCT04202250
- Testing
- CEMP (closed-ended multiport catheter) group, OESP (open-ended single port catheter) group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gulhane School of Medicine
Anesthesia, Local, Pain Control
Should Maxillary Buccal Infiltration Anesthesia be Given in a Closed Mouth Technique?
To study the patients' and dentists' perception of receiving/ administering maxillary buccal infiltration anesthesia using an open or closed mouth techniques
- Trial name
- NCT03921190
- Testing
- Local anesthesia
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Mammaplasty, Anesthesia, Conduction
PEC Block II in Mammoplasty Surgeries
Breast augmentation surgery is the top cosmetic surgery in USA with more then 300.000 cases performed annually. Pain is a common complications of the procedure accompanied of dyspnea and nausea due to the surgical manipulation.
- Conditions
- Mammaplasty, Anesthesia, Conduction, Analgesia, Analgesia, Patient-Controlled
- Trial name
- NCT03488888
- Testing
- Normal Saline 0,9%, Bupivacaine
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Knee Arthroplasty
Comparing Two Regional Anesthesia Interventions for Knee Arthroplasty.
Osteoarthritis of the knee is a common disease of the elderly and knee arthroplasty is indicated in severe cases to improve long term pain and function.
- Trial name
- NCT03944005
- Where
- 2 sites in Canada, United Kingdom
- Sponsor
- Western University, Canada
QLB vs TAPB, Quadratus Lumborum Block
Comparison of the Effects of Bilateral Transversus Abdominis Plane Block and Bilateral Quadratus Lumborum Block on Postoperative Analgesia in Patients Undergoing Midline Laparotomy
Midline incisions provide easy, rapid and excellent exposure of the abdominal cavity and are particularly used for complex, diagnostic or emergency procedures.
- Conditions
- QLB vs TAPB, Quadratus Lumborum Block, Transversus Abdominis Plane (TAP) Block
- Trial name
- NCT06950502
- Testing
- transversus abdominis plane block, Quadratus Lumborum Block (QLB), quadratus lumborum block using bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Anesthesia, Postoperative Pain
Lateral QL Block vs Intrathecal Morphine for Cesarean Section
Effective postoperative analgesia after cesarean delivery is essential for maternal recovery, early mobilization, breastfeeding, and maternal-infant bonding.
- Conditions
- Anesthesia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT07712783
- Testing
- Lateral Quadratus Lumborum Block, ıv morphine PCA, Intrathecal morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ondokuz Mayıs University
Back Pain, Lumbar
Massage and Electroacupuncture in Chronic Lumbar Pain
The aim of this study is to evaluate and compare in patients with chronic back pain two therapeutic interventions: a) the combination of massage and electroacupuncture; and b) the application of epidural analgesia in pain…
- Conditions
- Back Pain, Lumbar, Anesthesia, Local, Epidural
- Trial name
- NCT04108546
- Testing
- Electroacupuncture device, Epidural analgesia
- Where
- 2 sites in Greece
- Volunteers
- 110 people
- Sponsor
- University of Thessaly
Rehabilitation, Analgesia
Observational Prospective Study of Opiate-free Anesthesia for Anterior Total Hip Replacement
Opioid-free anesthesia (ATO) is a multimodal anaesthesia combining different analgesic and anesthetic modalities thus excluding opiates as an intraoperative.
- Conditions
- Rehabilitation, Analgesia, Anesthesia
- Trial name
- ASOPHA (NCT04112277)
- Testing
- Cumulative morphine consumption
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hôpital Privé Sévigné
Pain, Acute, Rib Fractures
Mid-point to Pleura Transverse Process Block Versus Thoracic Intervertebral Foramen Block
The analgesic effect of continuous mid-point to pleura transverse process block compared to the analgesic effect of continuous thoracic intervertebral foramen block, in patients with multiple rib fractures.
- Conditions
- Pain, Acute, Rib Fractures, Polytrauma
- Trial name
- NCT05348330
- Testing
- Thoracic intervertebral foramen block, Mid-point to pleura transverse process block
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- San Salvatore Hospital of L'Aquila
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