Clinical trials: Anaesthesia and Analgesia
Pain, Postoperative
Efficacy of Liposomal Bupivacaine Versus 0.25% Bupivacaine for Laparoscopic Urologic Surgery
A prospective, randomized comparison of bupivacaine to liposomal bupivacaine given by local injection at all the wound sites in patients undergoing robotic-assisted or laparoscopic urologic surgeries in an effort to determine…
- Trial name
- NCT02222129
- Testing
- Bupivacaine, liposomal bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 206 people
- Sponsor
- Knight, Richard, M.D.
Epidural; Anesthesia
Does Ultrasound Increase the First-pass Success of Epidural Space Identification in Obese Parturients
Obesity is associated with difficulties in epidural space catheterization. The investigators want to prove that a pre-procedural ultrasound exam of lumbar spine increase the first-pass success rate of the epidural space…
- Trial name
- NCT04352283
- Testing
- Preprocedural ultrasound exam of lumbar spine
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Caen
Pain, Postoperative, Anesthesia
Anaesthesiological Involvement in Postoperative Pain Treatment
This study aims to investigate the current organization and management of postoperative pain in Denmark, especially for invasive pain treatment modalities (epidural infusions, PCA and regional blocks), in a national survey…
- Conditions
- Pain, Postoperative, Anesthesia, Epidural Analgesia, Acute Pain
- Trial name
- NCT03496194
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Childbirth, Epidural; Anesthesia
Evaluation of the Impact of Ambulatory Epidural on Maternal Satisfaction During Delivery and Postpartum
Childbirth is a special event for women. Maternal satisfaction regarding childbirth is quite important, that is why this factor has to be taken into account.
- Trial name
- PERIDEAMBU (NCT06550570)
- Testing
- QEVA questionnaire
- Where
- 2 sites in France
- Volunteers
- 126 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Pain
Use of Sedation and Local Anesthesia in Meatotomy: A Prospective Comparison Study
The aim of the study is to prospectively investigate the feasibility, pain control, and outcome of meatotomy performed under sedation and local anaesthesia compared with general anaesthesia with and without patient block
- Trial name
- NCT00480519
- Testing
- Meatotomy
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Rabin Medical Center
Total Hip Replacement
Intrathecal Magnesium and Postoperative Analgesia
Magnesium is implicated in the activation of NMDA receptors by amino-excitatory acids in the central nervous system [1]. Magnesium deficiency is associated to an increased activation of these receptors, and to an increased…
- Trial name
- NCT00560092
- Testing
- intrathecal magnesium sulfate
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Knee Arthroscopy
Knee Arthroscopy for Pain Control
This study aims to determine the effectiveness of an anterolateral genicular nerve block and portal anesthesia in controlling pain in the perioperative period after knee arthroscopy.
- Trial name
- NCT06701175
- Testing
- Nerve Block, Portal Anesthesia
- Sponsor
- University of Alabama at Birmingham
Total Knee Arthroplasty
Local Infiltration Analgesia Versus Quadruple Nerve Blocks in Total Knee Arthroplasty.
Total knee arthroplasty (TKA) is one of the most common orthopedic surgical procedures and is associated with severe pain in the immediate postoperative period, thus limiting early recovery.
- Trial name
- LIAQ (NCT07477730)
- Testing
- Surgical local infiltration, Obturator nerve block, Femoral nerve block
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CMC Ambroise Paré
Anesthesia, Analgesia
Patient Reported Outcome After Bariatric Surgery
Prospective association study to analyse patients' outcome after bariatric surgery. Outcome comprises postoperative pain, analgesia, postoperative side-effects, long-lasting pain, patients' impairment in daily living.
- Conditions
- Anesthesia, Analgesia, Bariatric Surgery
- Trial name
- NCT03490630
- Where
- Switzerland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain, Infant, Newborn
Intravenous and Topical Analgesics for Procedural Pain in Neonates
This study will test which type of pain medication is best for the management of pain in newborn preterm and full-term infants having a deep intravenous cannula inserted.
- Trial name
- NCT00213200
- Testing
- morphine, amethocaine
- Where
- 2 sites in Canada
- Volunteers
- 108 people
- Sponsor
- The Hospital for Sick Children
Pain, Postoperative, Cardiac Surgery
Chest Wall Block After Sternotomy: Randomized Controlled Trial in Cardiac Surgery: (PABLOS Study)
The main objective is to compare the effectiveness of LocoRegional Anesthesia (LRA) (bilateral transverse thoracic block or bilateral parasternal block) in addition to standard management compared to standard management alone…
- Trial name
- PABLOS (NCT05345639)
- Testing
- LRA Loco-regional anesthesia, Standardized post-operative analgesia protocol
- Where
- France
- Volunteers
- 254 people
- Sponsor
- University Hospital, Angers
Thoracic Surgery, Videoassisted Thoracoscopic Surgery,One-lung Ventilation
The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores
This present study aims is to compare the effects of ultrasound-guided paravertebral block, intertransverse process block, and erector spinae plane block on postoperative opioid consumption, and pain scores in patients undergoing…
- Conditions
- Thoracic Surgery, Videoassisted Thoracoscopic Surgery,One-lung Ventilation, Regional Anaesthesia, Postoperative Analgesia
- Trial name
- NCT07578545
- Testing
- Paravertebral block group, İntertransverse process block group, Erector spinae plane block group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Antalya Training and Research Hospital
Post-operative Pain, Gynecologic Surgery
Ultrasound Guided Posterior Quadratus Lumborum Block for Postoperative Analgesia in Gynecologic Surgery
The challenge to achieve adequate analgesia has led to the development of directed, multi-modal protocols specific to management of post-laparoscopy pain in effort to decrease the amount of additional administration of narcotic…
- Conditions
- Post-operative Pain, Gynecologic Surgery, Regional Anesthesia
- Trial name
- NCT04549090
- Testing
- QL (quadratus lumborum) block administration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pedram Bral
Postoperative Pain, Cholecystectomy, Laparoscopic
M-TAPA vs ESPB for Postoperative Analgesia After Laparoscopic Cholecystectomy
Postoperative pain after laparoscopic cholecystectomy can negatively affect patient comfort, recovery, and opioid consumption. Regional abdominal wall blocks are commonly used as part of multimodal analgesia to improve…
- Trial name
- NCT07403682
- Testing
- Modifiye throcoabdominal nerve block through the perichondrial approach (M-TAPA), erector spinae plane block (ESPB)
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Analgesia Disorder, Anesthetic Complication Epidural
Effectiveness of Epidural Anesthesia for Thoracic and Abdominal Surgery
This study aims to evaluate the effectiveness of the epidural analgesia in patients having elective thoracic and abdominal surgery under general anesthesia combined with epidural analgesia in Siriraj Hospital.
- Conditions
- Analgesia Disorder, Anesthetic Complication Epidural, Adverse Reaction to Epidural Anesthesia
- Trial name
- NCT02315261
- Testing
- Elective Thoracic and Abdominal Surgery Patients
- Where
- Thailand
- Volunteers
- 364 people
- Sponsor
- Siriraj Hospital
Dental Anxiety, Pain Management
Wand STA vs SleeperOne for Pediatric Local Anesthesia (WASO-Kids)
This randomized, single-blind, split-mouth trial compares the acceptance of two computer-controlled local anaesthetic delivery (CCLAD) systems - Wand® STA and SleeperOne⑤ - in children aged 4-9 years undergoing comparable…
- Trial name
- WASO-Kids (NCT07754851)
- Testing
- Computer-controlled local anesthetic delivery system (pressure-sensing, single-tooth anesthesia type), Computer-controlled local anesthetic delivery system (corded, pen-style electronic type)
- Where
- Greece
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Pain, Anesthesia
Analgesia-Nociception Index Guided Intraoperative Remifentanil Administration Versus Standard Practice:Evaluation of Perioperative Opioid Use
This study compares two groups of patients undergoing a gynecological surgey under general anesthesia: one group in which intraoperative analgesia is guided by the Analgesia-nociception index, and another group in which…
- Trial name
- MONIDOL-ANI (NCT03498820)
- Testing
- Analgesia Nociception Index, Remifentanil
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia, Analgesia
Near Remote Method to Guide Performance of Regional Anesthesia
Ultrasound-guided regional anesthesia/analgesia techniques (or simply, 'regional blocks') have gained popularity as they can reduce, and sometimes even eliminate, the need for opiate analgesics (and, consequently, their side…
- Conditions
- Anesthesia, Analgesia, Nerve Block, Delivery of Healthcare
- Trial name
- NCT05968261
- Testing
- Real time 'near remote' guidance of regional blocks
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Glenio Mizubuti (MD, PhD)
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - International
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia in Czech Republic and Slovak Republic.
- Trial name
- OBAAMA-INT (NCT02380586)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 3,040 people
- Sponsor
- Brno University Hospital
Mastectomy, Segmental, Regional Anesthesia
Post-discharge Pain After Breast-surgery Treated by Paravertebral Block
Breast surgery is known being associated to a high risk of persistent post-operative pain, which has been related, among other factors, to a poorly treated acute pain.
- Trial name
- NCT03618459
- Testing
- Phone questionnaire
- Where
- Switzerland
- Volunteers
- 244 people
- Sponsor
- Samuele Ceruti
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