Clinical trials: Anaesthesia and Analgesia
Contraception, Pain, Acute
Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed.
- Conditions
- Contraception, Pain, Acute, Anesthesia, Local
- Trial name
- EPIC (NCT06960317)
- Testing
- Buffered Lidocaine, Unbuffered lidocaine, Xylocaine jelly 2%
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Postoperative Pain Breast Reduction, Mammaplasty
SPSIP Block for Pain Control After Breast Reduction Surgery
The goal of this clinical trial is to learn whether an ultrasound-guided serratus posterior superior intercostal plane block (SPSIP block) can lower the need for opioid pain medicine after breast reduction surgery.
- Conditions
- Postoperative Pain Breast Reduction, Mammaplasty, Analgesia, Nerve Block
- Trial name
- SPSIP-RM (NCT07657949)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block, Standard Perioperative Pain Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cumhuriyet University Hospital
Inguinal Hernia, Cryptorchidism
Caudal Versus Intravenous Dexmedetomidine for Supplementation of Caudal Analgesia in Children
The purpose of this study is to compare the effects of caudal dexmedetomidine with intravenous dexmedetomidine on caudal levobupivacaine analgesia in children undergoing lower abdominal surgeries.
- Trial name
- NCT01701778
- Testing
- Caudal Dexmedetomidine, Intravenous Dexmedetomidine, sevoflurane
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Yao Yusheng
Pulpitis, Pain Management
Effects of Topical Anesthesia Approaches on Dental Pain During and After Restorative Management of Dental Caries
The purpose of the Research Study and Overview of Participation: This study will compare different approaches used to prevent pain when giving local anesthesia to numb the teeth while managing dental cavities and decay.
- Trial name
- NCT07379515
- Testing
- Photobiomodulation (PBM)-induced analgesia device using multi-wavelength LED, Medicated analgesia
- Volunteers
- 204 people
- Sponsor
- Dubai Health
Obstetric Pain, Other Complications of Obstetric Anesthesia - Delivered
Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome
To assess the efficacy of epidural dexamethasone administration, compared to placebo, in reducing local anesthetics consumption during labor epidural analgesia in parturient women
- Trial name
- DEXAPER (NCT02857465)
- Testing
- Dexamethasone, Ropivacaine, Sufentanil
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Post Operative Pain
Dexmedetomidine Ropivacaine Versus Plain Ropivacaine in Bilateral Pectoralis Nerve Block
Background: Multimodal analgesia for control of postoperative pain in cardiac surgical patients helps in early recovery and ambulation.
- Trial name
- NCT05897307
- Testing
- Ropivacaine
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Fayoum University Hospital
Osteoarthritis, Hip
Systemic Steroids for Peripheral Nerve Blocks
This study will investigate the ability of systemic dexamethasone to prolong the sensory block duration for lumbar plexus nerve blockade.
- Trial name
- NCT02464176
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Varicose Vein, Postoperative Pain
Propofol Versus Volatile Anesthesia in Post Operative Pain Management
The study will test the hypothesis that patients anesthetized with propofol suffer less postoperative pain than those anesthetized with sevoflurane.
- Trial name
- NCT00712517
- Testing
- propofol, sevoflurane
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- The Cleveland Clinic
Postoperative Pain, Intra-articular Injection
Comparison of Intra-articular Dexmedetomidine and Magnesium in Postoperative Pain
Arthroscopic meniscus surgeries are the most frequent orthopedic procedures. The objective of the study is to compare the effects of intraarticular local anesthetic and adjuvant (dexmedetomidine vs magnesium) combinations in…
- Conditions
- Postoperative Pain, Intra-articular Injection, Dexmedetomidine, Magnesium Sulfate
- Trial name
- NCT03479216
- Testing
- Precedex, Magnesium Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Derince Training and Research Hospital
Rib Fractures
Continuous Intercostal Nerve Blockade for Traumatic Rib Fractures
Rib fractures are common injuries in accident patients and can be associated with significant pain during recovery. If poorly controlled, pain from splinting due to rib fractures can result in difficulty in breathing leading to…
- Trial name
- NCT02604589
- Testing
- hydromorphone hydrochloride, Infusion catheter placement, bupivicaine 0.25%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Anthony Iacco
Caesarean Section, Spinal Anesthesia
Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section
Cesarean section commonly induces moderate to severe pain for 48 hours. These patients have additional compelling reasons to provide adequate pain relief as early mobilization is a key factor to prevent the risk of thromboembolic…
- Conditions
- Caesarean Section, Spinal Anesthesia, Quadratus Lumborum Block, Analgesia
- Trial name
- NCT03199170
- Testing
- Intrathecal morphine, Bilateral Quadratus Lumborum Block, Intrathecal morphine with bilateral Quadratus Lumborum Block
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Surgery With General Anesthesia, Gynecologic Surgical Procedures
COMPARISON OF PLAIN BLOCKS FOR POSTOPERATIVE PAIN MANAGEMENT IN GYNECOLOGICAL ABDOMINAL SURGERIES
This study compares the effects of transversus abdominis plane (TAP) block, quadratus lumborum block (QLB), and erector spinae plane block (ESP) on postoperative morphine consumption, pain scores, patient satisfaction, and side…
- Conditions
- Surgery With General Anesthesia, Gynecologic Surgical Procedures, Plane Block, Postoperative Pain Management
- Trial name
- ESP QLB TAP (NCT07021105)
- Testing
- ESP Plane block, QLB plane block, TAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Angioplasty, Anaesthesia and Analgesia
Popliteal Block for Lower Limb Angioplasty
Endovascular revascularization is an effective procedure in treatment of chronic critical limb ischemia. The less invasive procedure in high risk patients produce the benefit to the patients.
- Trial name
- NCT04445480
- Testing
- Popliteal block, Control
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Anesthesia, Anesthesia Recovery Period
Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy.
Postoperative quality of recovery (QoR) could be related to anesthesia and postoperative analgesia. This study is exploring early QoR after radical prostatectomy in the two groups of anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Radical Prostatectomy, Patient Satisfaction
- Trial name
- QoR (NCT04587505)
- Testing
- Epidural anesthesia with light general anesthesia, Postoperative epidural analgesia, General anesthesia
- Where
- Croatia
- Volunteers
- 61 people
- Sponsor
- University Hospital of Split
Virtual Reality, Distraction
Virtual Reality (VR) Could Be a Good Alternative to Relaxing or Pain-relieving Medication
We want to investigate whether Virtual Reality (VR) could be a good alternative to the relaxing or pain-relieving medications that are often used to alleviate anxiety when patients undergo surgery under local anesthesia.
- Conditions
- Virtual Reality, Distraction, Elderly (people Aged 65 or More)
- Trial name
- NCT06649383
- Testing
- Virtual reality
- Where
- 2 sites in Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pether Jildenstal
Post Operative Pain, Regional Anesthesia Morbidity
Does ESP Block Reduce Pain and Opiates Consumption After Surgery
The patients will be randomly assigned to standard therapy or standard therapy+ESP nerve block. After surgery pain level and narcotic consumption will be measured, and vital signs and side effects will bo monitored for up to 72…
- Conditions
- Post Operative Pain, Regional Anesthesia Morbidity, Opioid-Related Disorders, Chronic Pain
- Trial name
- NCT05512897
- Testing
- erector spinea plane block
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Michael Dubilet MD
Post Operative Pain
Postoperative Analgesia in Patients Undergoing Elective Lumbar Fusion Operations Under General Anesthesia
It was proven that intrathecal opioids are considered as an effective means of pain control in several major surgical interventions including spine surgeries.
- Trial name
- NCT05338320
- Testing
- Ultrasound Guided Erector Spinae Plane Block, Intrathecal morphine, General anesthesia using intravenous fentanyl (1µg/kg)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Hip Arthroplasty, Postoperative Pain
DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery
This randomized, double-blind clinical trial aims to compare the effectiveness of the Deep Iliacus Plane Block (DIPB) and the Suprainguinal Fascia Iliaca Block (SIFIB) for postoperative pain control in patients undergoing primary…
- Conditions
- Hip Arthroplasty, Postoperative Pain, Regional Anesthesia, Acute Postoperative Pain
- Trial name
- NCT07452120
- Testing
- Suprainguinal Fascia Iliaca Block, Deep Iliacus Plane Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sivas Numune Hospital
Ultrasound-guided Regional Anesthesia, Shoulder Surgery
Distant Extrafascial Injection vs Subfascial Injection for Interscalene Block: Acute Pain Outcomes and Rates of Complications
The objective of this randomized controlled trial is to compare the analgesic efficacy and the safety profile between two techniques of injection for the interscalene block.
- Conditions
- Ultrasound-guided Regional Anesthesia, Shoulder Surgery, Interscalene Block, Postoperative Analgesia
- Trial name
- NCT02074397
- Testing
- Distant extrafascial injection, Subfascial injection
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Cancer of Pancreas
Effects of Epidural Anesthesia and Analgesia on the Prognosis in Patients Undergoing Pancreatic Cancer Surgery
The purpose of this randomized controlled trial is to investigate the effects of epidural anesthesia and analgesia on the overall survival，disease-free survival and recovery in patients undergoing pancreatic cancer surgery.
- Trial name
- NCT03245346
- Testing
- GEA, PCEA, GA
- Where
- 2 sites in China
- Volunteers
- 540 people
- Sponsor
- Fudan University
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