Clinical trials: Anaesthesia and Analgesia
Post-operative Pain, Anesthesia, Local
Evaluation of the Analgesic Benefit of Adding the Blocks of the Intermediate and Medial Femoral Cutaneous Nerves in Addition to the Femoral Triangle Block for Postoperative Analgesia After a Knee Replacement Surgery
Total knee replacement surgery can be associated with a significant postoperative pain burden and an inability to mobilize adequately, which can lead to the failure of the ambulatory course.
- Trial name
- NCT06038851
- Testing
- Para-Sartorial Compartments (PACS) Block, Femoral Triangle Block (FTB), Infiltration between popliteal artery and capsule of the knee (IPACK) block
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Hip Fractures, Anesthesia, Local
Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block
The main objective is to complete a double-blinded randomized controlled crossover trial of lumbar plexus block with the Shamrock technique guided by ultrasound (US)/magnetic resonance imaging (MRI) image fusion vs.
- Conditions
- Hip Fractures, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT02718976
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Hysterectomy, Post Operative Analgesia
Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use
The purpose of this study is to determine whether an injection of a local anesthetic (Bupivacaine with epinephrine) in the vaginal cuff prior to closure would result in less immediate postoperative pain medication and increase…
- Trial name
- NCT06719180
- Testing
- Bupivacain
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- MediSys Health Network
Pleural Neoplasms, Aspiration, Respiratory
Local Anesthesia Versus Combined Local Anesthesia With Single Dose Analgesia on Pain Control During Thoracic Ultrasound Guided Procedures
This study aims to evaluate the efficacy of single dose analgesia in combination with local anesthesia to control pain during Trans Ultrasound guided procedures.
- Conditions
- Pleural Neoplasms, Aspiration, Respiratory, Pleural Effusion, Lung Neoplasms
- Trial name
- NCT05121233
- Testing
- Diclofenac
- Volunteers
- 100 people
- Sponsor
- Assiut University
Orthopedic Disorder, Total Knee Replacement
Combined Adductor&Sciatic Nerve Block vs Femoral&Sciatic Nerve Block in Total Knee Replacement Surgery
Knee joints, one of the largest and most functional joints of the human body, have great features to provide ideal body posture and movement.
- Conditions
- Orthopedic Disorder, Total Knee Replacement, Post Operative Pain, Surgery
- Trial name
- NCT05648708
- Testing
- Combine Adductor Canal & Sciatic Nerve Block, Combine Femoral & Sciatic Nerve Block, Bupivacaine and prilocaine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis
- Trial name
- NCT05029726
- Testing
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- John O'Toole
Pain
Femoral Nerve Block Versus Adductor Canal Nerve Block for Peri-Operative Analgesia Following Anterior Cruciate Ligament (ACL) Reconstruction: Evaluation of Post-operative Pain and Strength
All patients over the age of 16 undergoing primary or revision anterior cruciate ligament reconstruction with the use of bone-patellar-bone autograft are eligible for the study.
- Trial name
- NCT03033589
- Testing
- Marcaine 0.25 % Injectable Solution
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Acute Pain, Pain, Postoperative
Supraclavicular Blocks for Post-Operative Pain Control in Supracondylar Fracture Fixation, a Retrospective Analysis of Single Shot Catheter Techniques
We hypothesize that patients who receive a supraclavicular block via Angiocath, placed intra-operatively and dosed post-operatively following neurologic examination, will have lower pain scores, lower use of intravenous morphine…
- Trial name
- NCT02210429
- Testing
- Elbow Fracture Fixation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pain, Analgesia
The Use of Micro Vibratory Stimulation Technique to Control the Pain of Digit Block Anesthesia
The investigators hypothesize that patients who receive 1% lidocaine injections for digit blocks of the finger will experience less pain when the injection is accompanied by the use of a micro-vibratory stimulator (MVS) compared…
- Trial name
- NCT02870595
- Testing
- Microvibratory Stimulator, Microvibratory Stimulator'
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Christus Spohn Memorial Medical Center
Erectile Dysfunction (ED)
IPP Placement & Intracavernosal Block
The inflatable penile prosthesis (IPP) is the gold standard for surgical management of erectile dysfunction (ED) and there is no consensus on the best postoperative pain management regimen.
- Trial name
- IPP (NCT07246642)
- Testing
- Exparel/bupivacaine mixture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences
Fractures, Dislocations
Ketamine Versus Fentanyl as an Adjunct to Propofol-Assisted Emergency Department Procedural Sedation
We, the investigators at Queen's University, propose to conduct a randomized, double-blind, feasibility trial comparing low-dose ketamine versus fentanyl as adjuncts to Emergency Department procedural sedation with propofol.
- Conditions
- Fractures, Dislocations, Abscess, Anesthesia
- Trial name
- NCT00137085
- Testing
- ketamine
- Where
- Canada
- Volunteers
- 124 people
- Sponsor
- Queen's University
Pain, Postoperative
Transversus Abdominis Plane Block Versus Ilioinguinal Nerve Block for Pain Management in Inguinal Herniorraphy
This study compares efficacy of transversus abdominis plane block and ilioinguinal nerve block for postoperative pain in patients undergoing inguinal herniorraphy with spinal anesthesia.
- Trial name
- NCT02375100
- Testing
- Spinal Anesthesia, Transversus Abdominis Plane Block, Ilioinguinal Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozyaka Training and Research Hospital
Acute Post Operative Pain, Hip Fracture
Pain Relief Comparison: Pericapsular Nerve Group Versus Quadratus Lumborum Block for Positioning in Femur Fracture Surgery
This study aims to compare the analgesic efficacy of Ultrasound Guided Pericapsular Nerve Group Block and Quadratus Lumborum Block for pain relief During patient Positioning for Spinal Anesthesia in proximal femur fracture…
- Conditions
- Acute Post Operative Pain, Hip Fracture, Regional Anaesthesia, Quadratus Lumborum Block
- Trial name
- NCT06917807
- Testing
- Pericapsuler nerve group block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Ain Shams University
Pain, Postoperative
Preemptive Local Anesthesia in Vaginal Surgery
Preemptive analgesia is an intervention which provides an anesthetic prior to initiating a painful stimulus. This trial is examining the effects of a local anesthetic given at the point of innervation prior to performing a…
- Trial name
- NCT00318292
- Testing
- bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Hernia, Inguinal
Spinal Versus Local Anesthesia for Hernia Repair
patients underwent inguinal hernia repair; Group A patients received Subarachnoid anesthesia; Group B Patients underwent surgery with local anesthesia (Mepivacaine 2%) performed by the surgeon; Pain assessment was performed using…
- Trial name
- SPINOFAST (NCT05136534)
- Testing
- spinal anesthesia, local anesthesia
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Campus Bio-Medico University
Adverse Anesthesia Outcome
Preemptive Analgesia Using Intravenous Paracetamol
Dental treatment for children should be done in a calm atmosphere and without pain. Oral Propacetamol has been shown to be effective in a variety of postsurgical pain models.
- Trial name
- NCT02884921
- Testing
- Paracetamol
- Volunteers
- 87 people
- Sponsor
- Bnai Zion Medical Center
Postoperative Delirium
Manual vs Automated Anesthesia : Impact On The Incidence Of POCD
This study will be the first study to report the combined use of three independent closed-loop systems together to assist clinicians in titrating anesthesia, analgesia, fluid and optimize ventilation in frailty old patients…
- Trial name
- NCT03148730
- Testing
- closed-loop group
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Erasme University Hospital
Anesthesia, Conduction
Lateral Cutaneous Nerve and PENG Blocks Versus Suprainguinal Fascia Iliaca Block in Post-op Analgesia of Hip Fractures
Postoperative pain in hip fractures is challenging and requires adequate management. Peripheral nerve blocks are already known as superior than systemic analgesia in this scenario, but the best analgesic regional technique is…
- Trial name
- NCT05749367
- Testing
- Ropivacaine + saline solution, Saline solution + Ropivacaine
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of Minas Gerais
Breast Cancer
Thoracic Spinal Anesthesia in Awake Breast Surgery
General anesthesia is the conventional technique used for breast surgery. breast surgery is associated with a high incidence of postoperative pain, it is estimated that over 50 % of women suffer chronic pain following breast…
- Trial name
- NCT03319511
- Testing
- spinal group, paravertebral group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Alaa Mazy
Postoperative Pain
External Oblique Intercostal Plane Block With or Without Rectus Sheath Block After Laparoscopic Cholecystectomy
This prospective observational cohort study compared postoperative pain outcomes in patients undergoing laparoscopic cholecystectomy who received bilateral external oblique intercostal plane block (EOIPB) alone or bilateral EOIPB…
- Trial name
- NCT07788911
- Testing
- Bilateral External Oblique Intercostal Plane Block, Bilateral Rectus Sheath Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
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