Clinical trials: Anal Fistulas
Fistula in Ano
Post-op Pain After Fistula Laser Closure or Ligation of the Intersphincteric Tract for Anal Fistula
This is a prospective, double-blinded randomised controlled trial conducted at two tertiary hospitals by a credentialed colorectal surgeon.
- Trial name
- LASERLIFT (NCT06212739)
- Testing
- Laser, LIFT
- Where
- Malaysia
- Volunteers
- 56 people
- Sponsor
- University of Malaya
Anal Fistula Surgery, Anal Fistula
Recurrence and Anal Fistula Patient Reported Outcomes Trial
Perianal fistulas are a chronic anorectal condition associated with significant morbidity, including pain, persistent discharge, infection, and impaired continence, all of which can substantially affect patients' quality of life.
- Conditions
- Anal Fistula Surgery, Anal Fistula, Perianal Fistula
- Trial name
- RAPPORT (NCT07477496)
- Testing
- Perianal fistula surgical repair
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Anal Fistula
Evaluation of the Recovery Rate and Postoperative Incontinence of Surgical Fistulas in a Cohort of a Reference Centre
Fistula is a pathology that can be complex and lead to treatment difficulties for the proctologist. The proctologist's objective is to treat the infection (anal fistula and abscess) with the minimum impact on anal continence.
- Trial name
- PROFIL (NCT03865823)
- Testing
- pus sample
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Fistula-in-ano
BioHealx® Anal Fistula Device Post Market Surveillance Study
This post market surveillance study is a single arm multicenter study to demonstrate the long-term durability and effectiveness of the BioHealx Anal Fistula Device for fistula-in-ano closure (internal and external fistula…
- Trial name
- NCT07021742
- Testing
- BioHealx
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Signum Surgical USA Inc.
Anal Fistula
Ligation of Intersphincteric Fistula Tract (LIFT) Procedure Versus Use of an Anal Fistula Plug for Anal Fistula Repair
Anal fistulae are a difficult problem to treat. The optimal treatment for fistula involving the anal sphincter is unclear. Two standardly used methods of treatment are the ligation of intersphincteric fistula track (LIFT)…
- Trial name
- LIFT vs PLUG (NCT00830661)
- Testing
- Ligation of intersphincteric fistula track procedure, anal fistula plug
- Where
- 4 sites in United States, Canada
- Volunteers
- 124 people
- Sponsor
- Colon and Rectal Surgery Associates, Ltd.
Anal Fistula
Cross-cultural Adaptation of the Chinese Version of QoLAF-Q (Quality of Life in Patients With Anal Fistula Questionnaire) ：A Multi-center Study
The investigators verify the reliability and practicality of the Chinese adaptation results of QoLAF-Q, which helps Chinese doctors better master the methods and techniques of quality of life assessment.
- Trial name
- NCT06962228
- Testing
- Anal fistula surgery
- Volunteers
- 150 people
- Sponsor
- Changhai Hospital
Crohn's Fistula
Darvadstrocel for Crohn's Fistula in the Realworld
Background Perianal fistula may affect 15-50% of patients with Crohn's disease (CD). Treatment is complex, requiring a multidisciplinary approach.
- Trial name
- NCT05742100
- Testing
- Darvadstrocel
- Where
- Spain
- Volunteers
- 73 people
- Sponsor
- Dolores Herreros Marcos
Complex Anal Fistula
LASER FiLaC™ (FISTULA LASER CLOSURE) : First-line Treatment of Complex Anal Fistulas
Complex anal fistula is a fistula whose treatment with fistulotomy would expose the patient to an excessive risk of post-operative continence disorders.
- Trial name
- NCT05201209
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Transsphincteric Anal Fistula
Ligation of Intersphincteric Track (LIFT) Versus Fistulectomy in Trans-sphincteric Anal Ffistula.
78 patients with transsphincteric fistula allocated into two groups group A underwent LIFT group B u nderwent fistulectomy , comparison between the outcome og both procedures
- Trial name
- professor (NCT04351074)
- Testing
- LIFT, fistulectomy
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Zagazig University
Anal Fistula
Imaging Template for Reporting Anal Fistula
Magnetic resonance imaging (MRI) is the most used diagnostic tool for pre-operative assessment of anal fistula. However, there is lack of standardization in reporting this investigation.
- Trial name
- ITRAF (NCT04541238)
- Testing
- MRI
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Treviso Regional Hospital
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection
Myriad™ Augmented Soft Tissue Reconstruction Registry
This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures.
- Conditions
- Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus
- Trial name
- MASTRR (NCT05243966)
- Testing
- Myriad Matrix™ and Myriad Morcells™
- Where
- 15 sites in United States
- Volunteers
- 800 people
- Sponsor
- Aroa Biosurgery Limited
Anal Fistula
Endorectal Three-dimensional Ultrasound in the Diagnosis of Cryptogenic Fistulas of the Rectum.
Prospective comparative parallel ultrasound diagnostic transrectal study in the diagnosis of cryptogenic fistulas of the rectum
- Trial name
- NCT03743701
- Testing
- The method of transrectal ultrasound in В-mode, The method of transrectal ultrasound examination using three-dimensional image reconstruction.
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Fistula in Ano
Role of Udumbara Sutra in the Management of Fistula in Ano a Rare Case Study
The anal fistula is a notorious disease due to its recurrence rate. Bhagandara is varyingly defined as a tear, ulcer or boil at Bhaga (Perianal region) within 2 finger circumference of it, causing painful abscess when opened is…
- Trial name
- Bhagandara (NCT01954225)
- Testing
- Udumbara Sutra
- Where
- India
- Volunteers
- 1 people
- Sponsor
- Government Ayurved College and Hospital
Anal Fistula
Efficacy and Safety of Adipose Stem Cells to Treat Complex Perianal Fistulas Not Associated to Crohn´s Disease
Anal fistula is defined as an abnormal communication between the anal canal and the perianal skin. Adipose-derived stem cells are a new therapy for the closure of these fistulas.
- Trial name
- FATT1 (NCT00475410)
- Testing
- ASCs (Cx401, company code), Fibrin adhesive
- Where
- 10 sites in Germany, Spain and 1 more
- Volunteers
- 214 people
- Sponsor
- Tigenix S.A.U.
Anal Fistula, Patient Discharge Education
Determining the Effect of Education Given to Patients Undergoing Outpatient Anal Fistula Surgery
It is emphasized that discharge education should shift from traditional healthcare provider-centered, one-way education to patient-centered education based on patient-care provider interaction to ensure patients' active…
- Conditions
- Anal Fistula, Patient Discharge Education, Outpatient Anal Surgery
- Trial name
- anal fistula (NCT07323160)
- Testing
- Teach-back discharge education
- Volunteers
- 76 people
- Sponsor
- Muğla Sıtkı Koçman University
Anal Fistula
Re-routing in Treatment High Anal Fistula
The aim of this study is to evaluate the role of rereouting in treatment of high anal fistula and evaluate the success rate, the recurrence and incontinence and see if rerouting of the track is a good choice in treatment of high…
- Trial name
- NCT05476146
- Testing
- Rerouting of the track in high anal fitula
- Volunteers
- 50 people
- Sponsor
- Assiut University
Perianal Abscess, Anal Fistula
Machine Learning-Based Risk Stratification for Fistula Formation After Perianal Abscess Drainage
This prospective cohort study investigates the influence of provider experience and drainage location on fistula formation within 6 months following perianal abscess drainage.
- Trial name
- PRISM (NCT07019532)
- Volunteers
- 450 people
- Sponsor
- Gumushane State Hospital
Wrist-Ankle Acupuncture
Application Effects of Wrist-Ankle Acupuncture in Patients With Different Types of Pain Following Perianal Surgery
This study is a prospective clinical observation designed to evaluate the analgesic effect of wrist-ankle acupuncture in patients with different types of pain after perianal surgery, as well as its applicability.
- Trial name
- NCT07340307
- Testing
- wrist-ankle acupuncture
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The Affiliated Hospital of Putian University
Anal Fistulas
Seton or Glue for Trans-sphincteric Anal Fistulas
Surgical treatment of perianal fistulas frequently affects fecal continence. Sphincter saving techniques like loose or cutting seton and fistulectomy with advancement of an endorectal flap have been advocated to minimize the risk…
- Trial name
- NCT00929630
- Testing
- transsphincteric Seton positioning, glue (Tissucol) treatment, Fistula closing with biological glue
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Societa Italiana di Chirurgia ColoRettale
Anal Fistula
INVESTIGATION OF THE EFFICACY OF FISTULA OBLITERATION BY STEAM ABLATION IN PERİANAL FISTULAS
Perianal fistula(PF) is one of the most frequent disease in anorectal disease.The incidence of PF is 8,6 -10 / 100 000 . The first surgical treatment is defined by Hippocrates in PF .This surgical treatment which found by…
- Trial name
- STEAM (NCT04811105)
- Testing
- steam ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital