Clinical trials: Analgesia, Cesarean
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Cesarean Section Complications
Magnesium Sulphate Versus Dexamethasone With TAP Block for Post-Cesarean Analgesia
This randomized, double-blind, controlled clinical trial will compare the effectiveness of a single intravenous dose of magnesium sulphate versus dexamethasone as an adjuvant to ultrasound-guided transversus abdominis plane (TAP)…
- Trial name
- NCT07773220
- Testing
- Magnesium Sulphate 500 mg, Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Khyber Teaching Hospital
Transversus Abdominis Plane (TAP) Block, Wound Infiltration
Ultrasound-guided Transversus Abdominis Plane Block Versus Local Wound Infiltration (TAP_WI)
The goal of this clinical trial is to learn if transversus abdominis plane (TAP) block will reduce the cumulative opioid consumption compared to local wound infiltration (WI).
- Conditions
- Transversus Abdominis Plane (TAP) Block, Wound Infiltration, Pain Score (VAS), Opioid Analgesia
- Trial name
- TAP (NCT06627946)
- Testing
- TAP group
- Where
- Bhutan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bhutan
Cesarean Delivery, Postpartum Comfort
Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks.
- Conditions
- Cesarean Delivery, Postpartum Comfort, Postpartum Pain, Post-operative Pain
- Trial name
- PACESS (NCT07102641)
- Testing
- Acetaminophen, NSAID (Ketorolac/Ibuprofen)
- Where
- United States
- Volunteers
- 825 people
- Sponsor
- Thomas Jefferson University
Over 18 Years Old
Innovative Methods in Postoperative Pain Management: A Study on the Effects of Kinesio Taping After Cesarean Section
Brief Summary: This randomized, single-blind study aimed to evaluate the effects of kinesio taping on pain management, comfort, and satisfaction of women after cesarean section.
- Trial name
- NCT06661109
- Testing
- Intervention (Kinesio Taping) group
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mersin University
Postoperative Pain, Patiet Controlled Analgesia
Comparison of the Effects of Hydromorphone and Nalbuphine Patient Controlled Analgesia in Postoperative Pain After Cesarean Section
Cesarean section is an essential surgical procedure in obstetrics, which not only addresses dystocia and certain obstetric syndromes, ensuring the safety of the maternal participants, but also increases perinatal survival rates…
- Trial name
- NCT06716359
- Testing
- Observational study without intervention
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Huazhong University of Science and Technology
Pregnancy, Analgesia
An Observational Study of Post-cesarean Delivery Respiratory Patterns Using a Non-invasive Minute Ventilation Monitor (Exspiron ™ System)
The purpose of this study is to evaluate the breathing patterns of women who undergo cesarean delivery with spinal or epidural morphine for post-operative pain control in the first day after surgery.
- Conditions
- Pregnancy, Analgesia, Respiratory Depression, Obstructive Sleep Apnea
- Trial name
- NCT02903173
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Duke University
Cesarean Section, Pain, Acute
Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study)
The investigators are comparing post operative analgesia provided for caesarean section patients, with the quadratus lumborum type 2 block and intrathecal morphine.
- Trial name
- NCT03267628
- Testing
- Intrathecal morphine as well as local anaesthetic in Blocks, Intrathecal morphine as well as saline in Block, Saline intrathecal as well as saline in Blocks
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr Willem Basson
Postoperative Pain
Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery
This study has been designed to determine if women undergoing cesarean delivery with spinal anesthesia and routine pain management who also have an additional ultrasound guided transversus abdominis plane (TAP)block using…
- Trial name
- NCT01261637
- Testing
- Ropivicaine
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Cesarean Delivery, Cesarean Delivery; Neuraxial Opioids
Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery
This study will examine whether addition of dexmedetomidine or clonidine (two alpha-2 adrenergic agonists) will improve the comfort of patients during spinal anesthesia for cesarean delivery.
- Conditions
- Cesarean Delivery, Cesarean Delivery; Neuraxial Opioids, Spinal Anesthesia for Cesarean Section, Dexmedetomidine
- Trial name
- NCT07567495
- Testing
- Clonidine, Dexmedetomidine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Parturients, Elective Cesarean Delivery
Maternal Satisfaction After Spinal Anesthesia for Cesarean Delivery
The goal of this observational study is to evaluate the impact of four different spinal anesthesia regimens on maternal satisfaction following cesarean delivery.
- Trial name
- NCT07438171
- Testing
- Bupivacaine %0.5 (hyperbaric), Bupivacaine %0.5 (hyperbaric) and morphine, Bupivacaine %0.5 (hyperbaric), morphine and fentanyl 15
- Volunteers
- 200 people
- Sponsor
- University of Novi Sad
Pregnancy, Cesarean Section
Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section
The goal of this randomized controlled clinical trial is to determine if low-dose intrathecal morphine is superior to a Transversus Abdominis Plane (TAP) block with ropivacaine and clonidine for postoperative analgesia in women…
- Conditions
- Pregnancy, Cesarean Section, Neuroaxial Analgesia Procedures
- Trial name
- MIRAGE (NCT07377630)
- Testing
- Intrathecal Morphine, TAP Block
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Giannina Gaslini
Failed Epidural Analgesia, Post-partum Recovery
Failing Epidural Analgesia During Labor
This prospective multicenter observational study is being conducted at the Gregorio Marañón University General Hospital and the La Paz University Hospital in Madrid, Spain.
- Trial name
- FEA25 (NCT07473609)
- Testing
- No Intervention: Observational Cohort
- Where
- 2 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Nicolas Brogly
Pain Management
Comparison of IV Nalbuphine Versus Ibuprofen for Postoperative Pain Control in Cesarean Section
The local data is insufficient to directly compare IV nalbuphine versus ibuprofen among people in this region. The findings of this study would add to the existing data and would be helpful for health providers to opt for a…
- Trial name
- NCT06594224
- Testing
- Ibuprofen, Nalbuphine
- Where
- 2 sites in Pakistan
- Volunteers
- 80 people
- Sponsor
- Muhammad Aamir Latif
Analgesia
Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia
Cesarean birth is a common surgical procedure. After cesarean birth, postsurgical pain may delay recovery, interfere with maternal-newborn bonding, and reduce the breastfeeding if not adequately controlled.
- Trial name
- TAB (NCT05785377)
- Testing
- Bupivacaine-Neostigmine, Bupivacaine
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Mansoura University
Anaesthesia, Spinal
Pain Control and Side Effects in Cesarean Section Anesthesia: Comparison of Intrathecal Morphine and Fentanyl
Intrathecal opioids are frequently combined with local anesthetics to optimize spinal anesthesia for cesarean delivery. Fentanyl, a lipophilic opioid, offers rapid onset and enhanced intraoperative analgesia.
- Trial name
- FvMinSACS (NCT07144410)
- Testing
- fentanyl + morphine, fentanyl
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oradea
Quality of Recovery, Elective Cesarean Section
Evaluating The Quality of Recovery After Elective Cesarean Section
Adequately validated patient-reported outcome measures are available, which can assess recovery profiles following childbirth. This study will explore the effect of two different methods for pain management on the quality of…
- Conditions
- Quality of Recovery, Elective Cesarean Section, Quadratus Lumborum Block, Patient Controlled Analgesia
- Trial name
- NCT06155968
- Testing
- QL block, PCA
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Epidural Anesthesia, Cesarean Section
A Comparison of Different Concentration Ropivacaine for Patient-controlled Epidural Analgesia
To compare the postoperative analgesic effect and the intensity of motor block in different concentration ropivacaine plus fentanyl when used epidurally with a patient-controlled analgesia device after Cesarean delivery.
- Trial name
- PCEA (NCT03195309)
- Testing
- Ropivacaine, Fentanyl
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Cesarean Section
Comparison of Modified Perichondral Approach Thoracoabdominal Nerve Block and Transversus Abdominal Plane Block in Analgesia Management Following Caesarean Section Surgery
Cesarean section (CS) is one of the most frequently performed surgical procedures in the World. Moderate to severe postoperative pain occurs in a significant proportion of women after cesarean surgery.
- Trial name
- NCT06185725
- Testing
- Modified Perichondral Approach Thoracoabdominal Nerve Block, Transversus Abdominal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Pain, Postoperative, Postoperative Complications
Evaluation of the Effect of Postoperative Analgesia Techniques With ObsQoR-10
The primary objective of this study is to evaluate the effects of postoperative analgesia techniques-transversus abdominis plane (TAP) block and wound infiltration-on recovery in patients undergoing elective cesarean section…
- Trial name
- NCT06978491
- Testing
- Group C, Group T, Group W
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University