Clinical trials: Analgesia, Cesarean
Post Operative Pain, Caesarean Section
Naldebain® Extended-release Injection After Cesarean Section in Pain Management
Cesarean section is one of the surgeries most commonly leading to postoperative severe acute pain. It was reported that the mean worst pain intensity reached to 6.14 one day after cesarean section in Germany.
- Conditions
- Post Operative Pain, Caesarean Section, Analgesia
- Trial name
- NCT05446311
- Testing
- Dinalbuphine sebacate
- Volunteers
- 20 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Cesarean Section, Cesarean Delivery
Pain Management After Cesarean Section - A Before-and-After Cohort Study
Inadequate pain relief remains a challenge after Cesarean section (CS) and may significantly impair postoperative recovery. A recent Danish single-center study (n=100) revealed that 66% of elective CS patients experienced severe…
- Conditions
- Cesarean Section, Cesarean Delivery, Pain Management, Pain Management in Postoperative Care
- Trial name
- NCT06813638
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Nordsjaellands Hospital
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Post Operative Pain
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
All participants will receive spinal anaesthesia and will be randomly divided into 2 equal groups. In Group 1, 20 ml of local anesthetic solution will be administered bilaterally to the rectus sheath space under direct vision…
- Trial name
- NCT06020196
- Testing
- surgical rectus sheath block, subdermal local anaesthetic infiltration
- Where
- Egypt
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ahmed M Maged, MD
Caesarean Section, Postoperative Analgesia
Analgesic Effects of Intrathecal Morphine and Transversalis Plane Block After Cesarean Delivery
A comparison of postoperative pain levels, patient satisfaction, and side effects is planned between patients who received morphine during spinal anesthesia for cesarean section and patients who did not receive morphine but…
- Trial name
- NCT07490795
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 117 people
- Sponsor
- Vezirköprü State Hospital
Pain, Post Operative, Cesarean Section Complications
Erector Spinae Plane Block (ESPB) Versus Quadratus Lumborum Block (QLB) for Postoperative Analgesia After Caesarean Section
Management of pain after caesarean section represents an important anesthesiologic issue, since it is often suboptimal, leading to delayed functional recovery and chronic pain.
- Conditions
- Pain, Post Operative, Cesarean Section Complications, Anesthesia, Local, Obstetric Anesthesia Problems
- Trial name
- NCT05348083
- Testing
- ESPB
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Complications; Cesarean Section
Preoperative Cesarean Section Intravenous Acetaminophen and Postoperative Pain Control
To evaluate the use of maternal opiates for pain control post cesarean delivery in those patients that received intravenous acetaminophen 1000 mg in 150 mL of normal saline, infused 30 minutes prior to incision compared to…
- Trial name
- NCT02694653
- Testing
- Acetaminophen
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
POSTOPERATIVE PAIN
Comparative Study of Two Different Techniques to Perform TAP-blocks
The TAP is a space between the muscle layers of the abdominal wall that houses nerves supplying the abdominal skin. Injecting the local anesthetic ropivacaine into this space will block these nerves and prevent pain following…
- Trial name
- Surgical-TAP (NCT02571439)
- Testing
- Surgical TAP block, Conventional TAP block, 0.5% ropivacaine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Maimonides Medical Center
Post-surgical Pain
Hydromorphone Hydrochloride Epidural Preemptive Analgesia for Postoperative Pain After Cesarean Section
Acute pain often occurs after cesarean section, which can lead to stress and inflammatory response in the body, which will not only affect the postpartum recovery speed of the puerpera, but also inhibit the secretion of prolactin…
- Trial name
- HHEPA (NCT06823180)
- Testing
- Hydromorphone hydrochloride low dose, Hydromorphone hydrochloride high dose, 0.9% sodium chloride
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Liquan Liang
Pain, Referred
Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section
The purpose of this study is to determine if giving an injection of numbing medication at the incision at the end of cesarean will help control pain AFTER cesarean delivery.
- Trial name
- NCT03383588
- Testing
- Bupivacaine, Morphine, Fentanyl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section: RCT
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT04637386
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Post-cesarean Pain Control Quality
Comparisons Between Low Thoracic and Lumbar Epidural Analgesia on Postoperative Pain Low Thoracic v.s. Lumbar Epidural for Post-cesarean Pain
Whether low thoracic epidural analgesia improves postoperative cesarean pain qualities than conventional lumbar epidural analgesia?
- Trial name
- NCT03946982
- Testing
- low thoracic epidural, lumbar epidural
- Where
- Taiwan
- Volunteers
- 189 people
- Sponsor
- National Taiwan University Hospital
Cesarean Section, Postoperative Pain
Ketamine for Analgesia After Cesarean Section
In this prospective randomized trial, investigators compared the analgesic effect of subanesthetic dose of ketamine versus placebo in parturients undergoing cesarean section under spinal anesthesia.
- Trial name
- NCT04545801
- Testing
- 0.25 mg/kg of Ketamine, 20ml of normal saline solution
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- Mongi Slim Hospital
Epidural Analgesia, Obstetric
Impact of Low-Dose Epidural Analgesia on Labour Progression in Low-Risk Women
Aim of the study was to analyse data on cervical dilation and fetal descent patterns in low-risk women, who did or did not receive intermittent low-dose epidural analgesia (EA), and who had either a vaginal or a caesarean…
- Trial name
- NCT06987591
- Where
- Italy
- Volunteers
- 5,995 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cesarean Section Complications
Erector Spinae Plane Versus Transversus Abdominis Plane Block for Pain Control
The present stratified randomized study aimed to compare the analgesic efficacy and safety profile of ESPB and TAPB used for postoperative pain management in obese and morbidly obese women undergoing CS.
- Trial name
- NCT06292832
- Testing
- Ultrasound-guided pain block, Ultrasound Machine
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Al-Azhar University
Postoperative Pain
Bilateral Transversus Abdominis Plane Block and Postoperative Pain Intensity After Elective Cesarean Delivery
The patients planned to go under elective cesarean delivery under general anesthesia are randomly assigned to have either bilateral transversus abdominis plane (TAP) block or usual standard analgesics after cesarean.
- Trial name
- TAP (NCT00964600)
- Testing
- TAP blockade
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Tehran University of Medical Sciences
Painless Labor, Epidural Analgesia
The Post Cesarean Section Analgesic Effect of Various Quadratus Lumborum Block Approaches
included patients were divided into 4 groups and each group received a mode of post cesarian section analgesia and pain was assessed by visual analogue scale at rest and movement. 1. st group epidural analgesia 2.
- Conditions
- Painless Labor, Epidural Analgesia, Cesarean Section
- Trial name
- NCT06393192
- Testing
- Epidural analgesia (EA) only group, Quadratus lumborum block (QL2), Quadratus lumborum block 3(QL3)
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Pain, Postoperative, Cesarean Section Complications
Satisfaction Following Cesarean Section
Presently, the standard of care at the investigators' practice is that the discharging physician decides the type and amount of opioid medication to prescribe a patient following a cesarean section.
- Conditions
- Pain, Postoperative, Cesarean Section Complications, Postpartum Disorder, Opioid Use
- Trial name
- NCT03355248
- Testing
- Oxycodone Acetaminophen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ProMedica Health System
Pain, Cesarean Section
Postcesarean Section Pain: Possible Demographic and Medical Predictors
The aim of this retrospective study is to find out if one or more of the following parameters has an impact on postcesarean section pain:age,ethnic origin, parity,body habitus, smoking, breastfeeding, education,newborn in…
- Trial name
- NCT00416104
- Where
- Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Postoperative Pain
Dexmedetomidine Wound Infiltration in Cesarean Section
The effects of four different wound infiltration protocols in cesarean section will be investigated on parturient' pain intensity, PCA morphine consumption given, side effects and parturient' overall satisfaction.
- Trial name
- NCT03382938
- Testing
- Dexmedetomidine, Ropivacaine, Dexmedetomidine - Ropivacaine
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital