Clinical trials: Analgesia, Cesarean
Pain, Postoperative
ITM + Bupivacaine QLB vs. ITM + Sham Saline QLB for Cesarean Delivery Pain
Comparison of standard post-operative cesarean surgery pain management with regional post-op pain control.
- Trial name
- qlcsection (NCT03261193)
- Testing
- ITM + Bupivacaine QLB
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Nicholas Schott
Cesarean Section Complications, Pain
Obstetric Liposomal Bupivacaine Via Surgical Transversus Abdominis Plane Block for Post Cesarean Pain Control
This study seeks to identify whether the addition of liposomal bupivacaine to regular bupivacaine and saline administered via surgical transversus abdominis plane (TAP) block will reduce the cumulative opioid dose in the first 48…
- Conditions
- Cesarean Section Complications, Pain, Opioid Use
- Trial name
- OBLiBupi (NCT04897841)
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride, saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cesarean Section
Comparison of 0.1 and 0.05mg Intrathecal Morphine for Post-cesarean Analgesia.
The purpose of this study is to determine the ideal dose of spinal morphine for use in Cesarean section. Spinal anesthesia (single injection in the lower back to numb patients from the waist down) is commonly used in Cesarean…
- Trial name
- NCT03427463
- Testing
- receiving 0.1 mg IT morphine, recieving 0.05 mg IT morphine
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Complex Obstetric Surgery, Perioperative Pain Management
COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block
To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean…
- Conditions
- Complex Obstetric Surgery, Perioperative Pain Management, Cesarean Delivery, Postoperative Pain Control
- Trial name
- COMFORT (NCT06925152)
- Testing
- Bupivicaine intervention arm
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Tennessee
Quality of Recovery, Elective Cesarean Section
Evaluating The Quality of Recovery After Elective Cesarean Section
Adequately validated patient-reported outcome measures are available, which can assess recovery profiles following childbirth. This study will explore the effect of two different methods for pain management on the quality of…
- Conditions
- Quality of Recovery, Elective Cesarean Section, Quadratus Lumborum Block, Patient Controlled Analgesia
- Trial name
- NCT06155968
- Testing
- QL block, PCA
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Parturients, Elective Cesarean Delivery
Maternal Satisfaction After Spinal Anesthesia for Cesarean Delivery
The goal of this observational study is to evaluate the impact of four different spinal anesthesia regimens on maternal satisfaction following cesarean delivery.
- Trial name
- NCT07438171
- Testing
- Bupivacaine %0.5 (hyperbaric), Bupivacaine %0.5 (hyperbaric) and morphine, Bupivacaine %0.5 (hyperbaric), morphine and fentanyl 15
- Volunteers
- 200 people
- Sponsor
- University of Novi Sad
Cesarean Section, Postoperative Pain
TAP vs QLB in Patients After Cesarean Delivery
Comparison of two types of analgesia after cesarean section All patients will be anesthetized with spinal technique. Ultrasound-guided transversus abdominis plane or quadratus lumborum block to treat postoperative pain.
- Trial name
- NCT03404908
- Testing
- TAP (transversus abdominis plane block), QL (quadratus lumborum block), Ropivacaine
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Lublin
Postoperative Pain
Dexamethasone for Post Cesarean Delivery Analgesia
The purpose of this study is to assess the effectiveness intravenous (IV) dexamethasone when used as part of a multimodal regimen to manage post cesarean delivery pain.
- Trial name
- NCT01868633
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Iowa
Analgesia, Acute Pain
Comparison of the Effects of QLB 2 and QLB 3 on Post-operative Analgesia in Cesarean Section Surgery
This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT04364906
- Testing
- Regional anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Morphine, Analgesics
Rescue Quadratus Lumborum Blocks for Post-cesarean Pain
The purpose of this study is to assess whether quadratus lumborum (QL) block performed 1 day after cesarean delivery will provide supplemental post-cesarean analgesia and reduce opioid requirements.
- Conditions
- Morphine, Analgesics, Analgesics, Opioid, Peripheral Nervous System Agents
- Trial name
- NCT04397458
- Testing
- Saline, Bupivacaine, Dexamethasone
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Cesarean Delivery
BUprenorphine Versus Morphine for Postcesarean Analgesia (BUMP)
In this study the researchers are randomizing pregnant patients coming for elective cesarean delivery to receive either intrathecal buprenorphine or morphine for their analgesia.
- Trial name
- NCT07786012
- Testing
- buprenorphine, morphine
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anesthesia, Analgesia
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients.
- Trial name
- NCT05514431
- Testing
- Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pain, Cesarean Section
Naproxen Versus Tramadol for Post Cesarean Pain Control
Oral naproxen might be more efficacious for post-cesarean pain-control and have better side-effects profile than oral tramadol.
- Trial name
- NCT01165814
- Testing
- Naproxen Tramadol
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Bnai Zion Medical Center
Pain, Postoperative
Usage of Tramadol With Levobupivacaine for Pain Treatment After Cesarean Section
Patients experience considerable amount of pain after cesarean section. The aim of this study is to investigate the effect of tramadol (an opioid pain killer) added to levobupivacaine (a local anesthetic) in continuous wound…
- Trial name
- NCT01916915
- Testing
- Tramadol infusion via wound catheter, Levobupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ufuk University
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT05447455
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Analgesia, Acute Pain
Comparison of the Effects of TFPB and Anterior QLB on Postoperative Analgesia in Cesarean Section Surgery
This study evaluates the postoperative analgesic effects of transversalis fascia plane block and anterior quadratus lumborum block in patients having cesarean section under general anesthesia.
- Conditions
- Analgesia, Acute Pain, Chronic Pain
- Trial name
- NCT05408403
- Testing
- Regional anesthesia TFPB, Regional anesthesia QLB
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Ondokuz Mayıs University
Cesarean Section Complications
Comparison of the Erector Spinae Plane Block Versus Intrathecal Morphine on Post-Cesarean Delivery Analgesia
This study is a Randomized Control Trial comparing the Erector Spinae Plane Block with intrathecal morphine for post cesarean delivery analgesia.
- Trial name
- ESPCS (NCT04256642)
- Testing
- Erector Spinae Plane Block, Intrathecal morphine
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Postsurgical Pain, Cesarean Section
Dinalbuphine Ester (Naldebain) for Pain Management After Cesarean Section
Inadequate postoperative pain management can lead to physical and psychological distress in patients as well as impact surgical wound healing and increase the risk of developing postoperative delirium and cardiopulmonary and…
- Conditions
- Postsurgical Pain, Cesarean Section, Chronic Post-surgical Pain
- Trial name
- NCT06344169
- Testing
- Sebacoyl Dinalbuphine Ester, Morphine
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital
Post Operative Pain, Cesarean Section Complications
Quercetin Effect on Post-ceserean Pain
The cesarean section is a common gynecological surgery, requiring effective pain management to prevent complications and immobility.
- Trial name
- NCT06650891
- Testing
- Quercetin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Future University in Egypt
Analgesia
Tab Block and Patient Controlled Analgesia in CS
cesarean section rate become increasing nowadays
- Trial name
- NCT04405336
- Testing
- tab block, PCA, women who will not receive tab block or PCA
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital