Clinical trials: Analgesia, Postoperative
Cesarean Section
Efficacy of Modified Perichondral Approach Thoracoabdominal Nerve Block For Post Cesarean Section
Cesarean section (CS) is one of the most frequently performed surgical procedures in the World. Moderate to severe postoperative pain occurs in a significant proportion of women after cesarean surgery.
- Trial name
- NCT06078475
- Testing
- Postoperative analgesia management
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Caudal Epidural Anesthesia, Sacral Erector Spinae Plane Block
Comparison of Erector Spinae Plane Block and Caudal Block for Postoperative Analgesia in Pediatric Patients Undergoing Orchiopexy: A Prospective Observational Study
This study aims to compare the analgesic efficacy of ultrasound-guided erector spinae plane block and caudal block for postoperative pain management in pediatric patients undergoing orchiopexy.
- Conditions
- Caudal Epidural Anesthesia, Sacral Erector Spinae Plane Block, Orchiopexy, FLACC Scale
- Trial name
- NCT07762339
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Cesarean Section Complications
Magnesium Sulphate Versus Dexamethasone With TAP Block for Post-Cesarean Analgesia
This randomized, double-blind, controlled clinical trial will compare the effectiveness of a single intravenous dose of magnesium sulphate versus dexamethasone as an adjuvant to ultrasound-guided transversus abdominis plane (TAP)…
- Trial name
- NCT07773220
- Testing
- Magnesium Sulphate 500 mg, Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Khyber Teaching Hospital
Knee Arthroscopic Surgery, Analgesia
Ultrasound Guided Femoral Nerve Block Versus Adductor Canal Block by Using Bupivacaine and Magnesium Sulphate for Post-Operative Analgesia
Ultrasound Guided Femoral Nerve Block versus Adductor Canal Block by Using Bupivacaine and Magnesium Sulphate
- Conditions
- Knee Arthroscopic Surgery, Analgesia, Femoral Nerve Block (FNB)
- Trial name
- NCT07838480
- Testing
- Group I: control group, Group II: Ultrasound Guided Femoral Nerve Block, group III : Adductor Canal Block group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Anxiety, Children
The Effect of Parental Anxiety Level on the Child's Anxiety Level and Postoperative Pain in Children Undergoing Surgery.
The aim of this prospective study is to investigate whether the anxiety levels of parents of children aged 2-6 years who will undergo inguinal area surgery have an effect on the child\'s preoperative anxiety level and…
- Trial name
- NCT06404879
- Testing
- determining scores with tests
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Giresun University
Postoperative Analgesia, Transversus Abdominis Plane (TAP) Block
Transversalis Fascia Plane Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Children
This prospective clinical study aims to compare the postoperative analgesic efficacy of the ultrasound-guided transversalis fascia plane block (TFPB) and the transversus abdominis plane (TAP) block in pediatric patients…
- Conditions
- Postoperative Analgesia, Transversus Abdominis Plane (TAP) Block, Transversalis Fascia Plane Block, Pediatric Surgical Procedures
- Trial name
- NCT07242196
- Testing
- Postoperative analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Analgesia, Pain, Postoperative
Effects of Intraoperative Magnesium Sulfate on Perioperative Pain Relief After Spine Surgery
The treatment of postoperative pain is increasingly based on a multimodal approach and although opioids remain the drug of choice, they are often used in combination with other analgesics (paracetamol, cyclooxygenase inhibitors…
- Conditions
- Analgesia, Pain, Postoperative, Spine Disease
- Trial name
- NCT04161729
- Testing
- Magnesium Sulfate, Isotonic saline 0.9%
- Where
- Greece
- Volunteers
- 74 people
- Sponsor
- Aristotle University Of Thessaloniki
Rotator Cuff Tear Arthropathy, Post Operative Pain
Effect of Radiofrequency of Suprascapular Nerve in Shoulder Reverse Arthroplasty
The purpuse of this study is to asses if the pulsed radiofrecuency of the supraescapular nerve and accesory nerve have the same or superior efectivity controlling the acute postoperative pain than interscalenic braquial plexus…
- Trial name
- NCT05785572
- Testing
- supraescapular nerve radiofrequency, interescalenic braquial plexus
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Hospital Universitario Virgen Macarena
Post-operative Pain
Post-operative Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have undergo orthopedic day surgical procedures for definitive management of fractures, tendon release, etc.
- Trial name
- NCT01686802
- Testing
- oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain, Acute, Regional Anesthesia
Comparation of Bilateral and Unilateral Erector Spinae Plane Block
Although laparoscopic cholecystectomy is a minimally invasive surgery with many advantages, it is one of the operations with high postoperative pain scores. Opioids are frequently used to prevent postoperative pain.
- Conditions
- Postoperative Pain, Acute, Regional Anesthesia, Multimodal Analgesia
- Trial name
- NCT05152602
- Testing
- Bilateral Erector spinae plane block, Unilateral Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Pain, Postoperative
PENG vs. Femoral Nerve Block for Pain Control in Hip Surgery
The aim of this study is to compare the efficacy of the ultrasound- guided pericapsular nerve group (PENG) block versus the femoral nerve block (FNB) for postoperative pain control in patients undergoing hip surgeries…
- Trial name
- NCT07597551
- Testing
- PENG BLOCK, Femoral nerve block
- Volunteers
- 100 people
- Sponsor
- Benha University
Ventilator Weaning, Airway Extubation
Can a Pain Monitor Predict When Postoperative Intensive Care Unit Patients Are Ready to Breathe on Their Own? A Pilot Study
The goal of this observational study is to learn if a chest monitor that tracks heart rhythm can help predict whether adults on a breathing machine after surgery will be able to breathe on their own once the breathing tube is…
- Conditions
- Ventilator Weaning, Airway Extubation, Respiration, Artificial
- Trial name
- NCT07771101
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain, Analgesia
Comparison of Erector Spina Plan Block and Rhomboid Intercostal Block in Breast Surgery
In this study, the investigators compared ultrasound-guided erector spinae plane (ESP) block and rhomboid intercostal block (RIB) on postoperative analgesic effect in unilateral breast surgery.
- Trial name
- NCT06177665
- Testing
- Erector Spinae Plane Block, Rhomboid Intercostal Block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Kocaeli University
Postoperative Pain
TAP Block With Magnesium Sulfate Added to Local Anesthetic in Abdominal Hysterectomy
Major abdominal surgeries are associated with severe abdominal pain, which can affect respiratory and cardiac functions, if insufficiently managed. This increases the incidence of post-operative morbidity.
- Trial name
- NCT02930707
- Testing
- Magnesium Sulfate, Bupivacaine
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pain, Pain Syndrome
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06072001
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Postoperative Pain
Thoracic Paravertebral Block Versus IV Fentanyl Infusion
High-quality analgesia during and following cardiac surgery is infrequently obtained, Sternotomy and thoracotomy is associated with significant pain that resulte in hypoventilation, atelectasis, and hypoxemia,Pain management is…
- Trial name
- NCT03903367
- Testing
- Fentanyl Citrate
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Beni-Suef University
Post Operative Pain
Comparison of M-TAPA and TAP Blocks on Postoperative Analgesia in Laparoscopic Inguinal Hernia Surgeries
The goal of this study is to compare the analgesic efficacy of M-TAPA block and TAP block in patients undergoing laparoscopic inguinal hernia surgeries.
- Trial name
- NCT06483607
- Testing
- M-TAPA block with bupivacaine 25%, TAP block with bupivacaine 25%
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cumhuriyet University
CABG, Physiological Parameter
The Effect of Virtual Reality and Eye Mask During Dressing After CABG Surgery
This study aims to evaluate the effects of virtual reality (VR) and eye mask (EM) applications on pain, anxiety, and physiological parameters during dressing after Coronary Artery Bypass Graft (CABG) surgery.
- Conditions
- CABG, Physiological Parameter, Postoperative Pain, Postoperative Anxiety
- Trial name
- CABG (NCT07039812)
- Testing
- Virtual Reality Headset, Eye Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul University - Cerrahpasa
Photorefractive Keratectomy, Myopia
Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control
Photorefractive Keratectomy (PRK) is a commonly performed corneal refractive surgery but has significant post-operative pain. Pain medications after PRK are typically opioid-acetaminophen combinations.
- Conditions
- Photorefractive Keratectomy, Myopia, Hyperopia
- Trial name
- NCT05477875
- Testing
- oral cannabinoid, oral codeine/acetaminophen
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Florida
Postoperative Pain
Pain Control of Thoracoscopic Major Pulmonary Resection
The purpose of this study is to evaluate whether pre-emptive local bupivacaine injection is a better alternative pain control modality than the conventional intravenous patient controlled analgesia.
- Trial name
- NCT01758809
- Testing
- Pre-emptive bupivacaine wound infiltration, intravenous patient controlled analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
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