Clinical trials: Analgesia, Postoperative
Inguinal Hernia, Nausea
Intrathecal Morphine for Inguinal Hernia Repair.
The aim of this study was to compare the effects of two different doses of intrathecal morphine (0.1 mg and 0.4 mg) combined with 7.5 mg of heavy bupivacaine on postoperative block regression times, postoperative analgesia and…
- Conditions
- Inguinal Hernia, Nausea, Vomiting, Pruritus
- Trial name
- NCT02001948
- Testing
- intrathecal morphine 0.1 mg combined with intrathecal heavy bupivacaine 7.5 mg, intrathecal morphine 0.4 mg combined with intrathecal heavy bupivacaine 7.5 mg, standard monitoring with Datex Ohmeda anesthesia monitor, GE, Finland
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ankara University
Analgesia
Preemptive Tapentadol on Post-operative Analgesia Following Total Knee Arthroplasty
The study intends to evaluate the efficacy of Tapentadol against placebo as a preemptive analgesic in the management of post-operative pain in the patiens undergoing total knee arthroplasty.
- Trial name
- NCT03351517
- Testing
- Tapentadol 100 MG
- Where
- India
- Volunteers
- 90 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Pain, Postoperative
Morphine-Sparing Efficacy Of Parecoxib In Pain Treatment After Radical Prostatectomy
The primary objective of this study is to demonstrate the opioid-sparing efficacy of parecoxib 40 mg intravenously given as a loading dose followed by 20 mg intravenously in the 24 hours after the end of surgery.
- Trial name
- PROSTATECTOMY (NCT00346268)
- Testing
- Morphine, Parecoxib
- Where
- 4 sites in Germany
- Volunteers
- 105 people
- Sponsor
- Pfizer
Cesarean Section, Postoperative Analgesia
Anterior Quadratus Lumborum Block Versus Erector Spinae Plane Block After Elective Cesarean Section
Cesarean section is the one of the most common surgical procedures. Inadequate pain management is associated with increased morbidity, costs, and maternal dissatisfaction.
- Trial name
- NCT05254093
- Testing
- Quadratus lumborum block, erector spinae plane block
- Where
- Egypt
- Volunteers
- 153 people
- Sponsor
- Kasr El Aini Hospital
Pain, Postoperative
Reducing Opioid Use and Misuse After Wisdom Molar Extractions
Reducing opioid prescription related use and misuse is a major focus for countering the national epidemic of opioid overdose and death.
- Trial name
- NCT04414917
- Testing
- Twin block, iPill dispenser
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Hip Arthropathy
ESP Block vs FIB in Patients Undergoing Hip Arthroplasty
The aim of this study is to compare between the analgesic efficacy of ESP block and FIB in patients undergoing hip arthroplasty.
- Trial name
- NCT05015517
- Testing
- Erector spinae plain block, Fascia Iliaca block
- Volunteers
- 54 people
- Sponsor
- Cairo University
for Post-operative Pain Relief in Spine Surgeries
Low Dose Perioperative Ketamine Infusion and it's Effect on Postoperative Pain Score, Sedation Score and Narcotic Consumption in Patients Undergoing Spine Surgery: A Prospective Randomized Double Blind Control Trial.
Low dose perioperative ketamine infusion and it's effect on postoperative pain score, sedation score and narcotic consumption in patients undergoing spine surgery: A prospective randomized double blind control trial.
- Trial name
- NCT04259476
- Testing
- Ketamine Hydrochloride
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Myopia, Hyperopia
Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRK
To determine the ability of two topical Nonsteroidal Anti-inflammatory drops (Acular LS \& Nevanac) to help control pain following Photorefractive Keratectomy (PRK).
- Trial name
- NCT00347204
- Testing
- ketorolac (Acular LS), Nepafenac (Nevanac)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Center For Excellence In Eye Care
Post Operative Analgesia
Post Operative Pain Control: Morphine vs Fentanyl
Aim of this study is to compare benefits and disadvantages in using continuous infusion of morphine or fentanyl for post operative analgesia.
- Trial name
- NCT02146638
- Testing
- Morphine, Fentanyl
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Catholic University of the Sacred Heart
Postoperative Pain
Dexamethasone Twice for Pain Treatment of Total Knee Arthroplasty
Dexamethasone twice for pain treatment after total knee arthroplasty - A Placebo-controlled, randomised, parallel 3-group multicentre trial of one and two doses of dexamethasone for postoperative treatment
- Trial name
- DEX-2-TKA (NCT03506789)
- Testing
- Dexamethasone
- Where
- 5 sites in Denmark
- Volunteers
- 485 people
- Sponsor
- Naestved Hospital
Rectus Sheath Block, Transverse Abdominis Plane Block
Rectus Sheath Block Versus Transversus Abdominis Plane Block for Analgesia in Laparoscopic Bariatric Surgery
This randomized controlled trial aims to compare the analgesic efficacy of rectus sheath block (RSB) and transversus abdominis plane block (TAPB) in patients undergoing laparoscopic bariatric surgery.
- Conditions
- Rectus Sheath Block, Transverse Abdominis Plane Block, Opioid Consumption, Postoperative, Analgesia
- Trial name
- RSB-TAPB (NCT07592091)
- Testing
- Rectus Sheath Block, Transversus Abdominis Plane Block
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Chiang Mai University
Pain, Postoperative, Abdominoplasty
Quadratus Lumborum Block for Abdominoplasty
Double blinded, randomized, controlled, phase IV intervention trial. Both groups will receive a quadratus lumborum Block (QL), using ropivacaine 3.75 mg/mL in the intervention group, and sterile sodium chloride in the control…
- Trial name
- NCT02949778
- Testing
- QL-block, Ropivacaine, Sodium Chloride
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Vestre Viken Hospital Trust
Arthroscopic Rotator Cuff Repair
Shoulder Anterior Capsular Block for Postoperative Analgesia in Arthroscopic Rotator Cuff Repair Surgery
Shoulder pain is frequently encountered in the medical field. Rotator cuff tears are the most common cause. Shoulder pain affects quality of life and delay rehabilitation programs.
- Trial name
- NCT06969625
- Testing
- (SHAC) block, (SSNB-ANB) block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Cesarean Section
Preoperative Epidural Labor Analgesia and Postoperative Pain
Parturients who undergo emergency Cesarean section (C-sec) after experiencing labor pain are likely to develop pain-induced central sensitization.
- Trial name
- NCT03381690
- Testing
- Epidural labor analgesia
- Where
- South Korea
- Volunteers
- 222 people
- Sponsor
- Seoul National University Bundang Hospital
Post Operative Pain
Peri Tonsillar Infiltration of Ketamine or Bupivacaine for Post Tonsillectomy Analgesia
Comparison between the analgesic effect of local infiltration of either Bupivacaine or ketamine in the peritonsillar area before the incision of tonsillectomy to achieve postoperative analgesia
- Trial name
- NCT05341323
- Testing
- Ketamine., Bupivacaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Pain, Postoperative, Serratus Anterior Plane Block
Comparison of Deep Serratus Anterior Plane Block and Combination of Deep and Superficial Serratus Anterior Plane Block
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Pain, Postoperative, Serratus Anterior Plane Block, Multimodal Analgesia, Thoracic Surgery, Video-Assisted
- Trial name
- NCT05106283
- Testing
- Deep block and Combined Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Pain, Postoperative
Low Dose Caudal VS Dorsal Penile Nerve Block for Postoperative Analgesia After Circumcision
in order to eliminate fear and anxiety. Regional techniques are more effective than systemic opioids, non steroidal anti-inflammatory drugs, and acetaminophen for postoperative analgesia in circumcision, The most preferred…
- Trial name
- NCT05342259
- Testing
- Caudal nerve block /neuroaxial, Dorsal penile nerve block, Combined caudal and dorsal penile nerve block
- Where
- Egypt
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Knee Osteoarthritis, Total Knee Arthroplasty
Effect of Preoperative Cold Therapy on Early Postoperative Outcomes in Total Knee Arthroplasty
This prospective, single-center, randomized controlled trial investigates the effects of preoperative cold therapy on early postoperative outcomes in patients undergoing unilateral primary total knee arthroplasty (TKA).
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Cryotherapy, Postoperative Pain Management
- Trial name
- NCT07134283
- Testing
- Preoperative and Postoperative Cold Therapy with Gel Cold Pack, Postoperative Cold Therapy with Gel Cold Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people
- Sponsor
- Ankara City Hospital Bilkent
Shoulder Pain, Shoulder Injuries
Serratus Posterior Superior Intercostal Plane Block for Arthroscopic Shoulder Surgery
Postoperative pain is a significant problem in patients undergoing arthroscopic shoulder surgery. This situation disrupts the patient's comfort and affects the functional outcome after surgery by preventing early rehabilitation.
- Trial name
- NCT06866054
- Testing
- SPSIPB block, Postoperative analgesia management
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Pain, Postoperative, Pain, Chronic
Naldebain for Pain Control After Bariatric Surgery
Laparoscopic gastric sleeve and bypass surgeries the most common bariatric procedures for weight loss and improved management of metabolic syndromes.
- Conditions
- Pain, Postoperative, Pain, Chronic, Bariatric Surgery, Obesity
- Trial name
- NCT04651361
- Testing
- Dinalbuphine sebacate
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- E-DA Hospital
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