Clinical trials: Analgesia, Postoperative
Post Operative Pain
Pre-incision Versus Lapaorscopic-assisted Transversus Abdominis Plane (TAP) and Rectus Sheath Block for Post-Cholecystectomy Pain
The goal of this clinical trial is to compare pre-incision vs laparoscopic assisted Transversus abdominis plane and rectus sheath block in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT05856682
- Testing
- Laparoscopic-assisted TAP block(LATAP) and Rectus Sheath block
- Where
- Pakistan
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Patel Hospital, Pakistan
Postoperative Pain, Inflammatory Response
Bilateral Ultrasound Guided Quadratus Lumborum Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response in Abdominal Surgery
This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.
- Trial name
- NCT03958942
- Testing
- Ultrasound quadratus lumborum block with bupivacaine 25%, lumbar epideural block with bupivacaine 25%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Pain, Shoulder Pain
Regional Analgesia for Anterior Cervical Disc and Fusion Surgery
Erector Spina Plane (ESP) block has been widely used in recent years, and it is also used in the control of postoperative analgesia in many types of surgery due to its proximity to the central area and its wide spread feature.
- Conditions
- Postoperative Pain, Shoulder Pain, Anesthesia, Local, Disc Herniation
- Trial name
- NCT05680142
- Testing
- superficial cervical plexus block, cervical erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Postoperative Pain
Ketamine for Pain Relief in Bariatric Surgery
The surgical interventions for treating morbid obesity, i.e. bypass procedure and sleeve gastrectomy are collectively covered under the term 'bariatric surgery'.
- Trial name
- NCT03052673
- Testing
- Fentanyl, ketamine
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Sir Ganga Ram Hospital
Post Operative Pain
Comparison Between Bupivacaine and Bupivacaine With Dexmedetomidine in Caudal Block for Post Operative Pain Control
The aim of this study is to compare the duration of analgesia, sedation, and intra and postoperative hemodynamics. This drug is recently available in Pakistan.
- Trial name
- NCT05919173
- Testing
- Bupivacaine Hydrochloride 0.25% Injection Solution, Bupivacaine Hydrochloride 0.25% Injection plus Dexmedetomidine 1 microgram/kg body weight
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Postoperative Pain After Cesarean Section
TAP vs. ESP Blocks for Post-Cesarean Analgesia
This study compares the effectiveness of two ultrasound-guided nerve blocks (TAP block and ESP block) versus standard pain management for relieving pain after a planned cesarean section.
- Trial name
- RCT-TAP-ESP-CS (NCT07853482)
- Testing
- Ropivacaine, Ultrasound-guided Nerve Block, Ketoprofen and Paracetamol
- Where
- Russia
- Volunteers
- 162 people
- Sponsor
- Maternity Hospital - State Budgetary Institution of the Rostov Region, Taganrog
Idiopathic Scoliosis
Analysis of Different Postoperative Analgesia Strategies Following Scoliosis Surgery
Idiopathic scoliosis surgery is a major surgery, causing significant post-operative pain which can have a significant impact, both for the patient and for society.
- Trial name
- SAPOS (NCT06194279)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Pain Management, Analgesia, Postoperative
Pain Management Protocol in Abdominal Surgeries in City of Erbil
Intervention Our study involves a novel multimodal pain management protocol for postoperative pain management. The protocol consists of 4 main phases: preoperative, intraoperative, postoperative, and post-discharge phases with…
- Trial name
- EPMP (NCT07019103)
- Testing
- Gabapentin (Neurontin® (Registered Trademark))
- Where
- Iraq
- Volunteers
- 136 people
- Sponsor
- Haroon Muhammad Khalil
Pain, Postoperative, Postoperative Pain
Intraperitoneal Aerosolized Delivery of a Local Anesthetic for Post Operative Pain Management. A Double Blind, Randomised Controlled Clinical Trial.
The purpose of this study is to determine the effectiveness of aerosolized pain medication (.5% bupivicaine) delivered into the peritoneal cavity after laparoscopic gastric bypass surgery.
- Conditions
- Pain, Postoperative, Postoperative Pain, Abdominal Pain, Obesity
- Trial name
- NCT00286286
- Testing
- Intraperitoneal Aerosolization System, IntraMyst
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Northgate Technologies
Pain, Ankle Injuries
Erector Spinae Plane Block and Ankle and Foot Surgery
Regional anesthesia is commonly used in orthopedic and surgical procedures in ankle and foot surgery to manage pain. The ultrasound-guided nerve block is a safe and effective regional anesthesia technique that provides effective…
- Trial name
- NCT05708742
- Testing
- Ultrasound, Bupivacaine Hydrochloride, saline solution
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Pain, Postoperative, Respiratory Complication
Thoracic Epidural Analgesia and Bilateral Erector Spinae Plane Block on Postoperative Pain in Open Heart Surgeries
Postoperative pain negatively effects respiratory functions in open heart surgeries. The aim of the study is to compare the effects of thoracic epidural analgesia (TEA) and erector spinae plane block (ESPB) on postoperative pain…
- Trial name
- NCT06098859
- Testing
- Thoracic epidural analgesia, Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Cesarean
Cesarean Postoperative Pain Satisfaction
Hypothesis: There is no significant difference in Cesarean patients' perceptions of overall pain management satisfaction between methods used for postoperative pain management.
- Trial name
- NCT00922142
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Saint Elizabeth Regional Medical Center
Pain
Local Infiltration Analgesia After Abdominal Hysterectomy
The aim of the study is to evaluate traditional analgesic therapy after abdominal hysterectomy with single infiltration of local anesthetics in the surgical area at the end of surgery.
- Trial name
- LIA (NCT01782781)
- Testing
- ropivacaine, ketorelac and epinephrine
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Postoperative Pain
Effects of TAP and QLB-1 Blocks on Opioid Consumption
Laparoscopic cholecystectomy is associated with less pain than open surgery and a shorter recovery time. While the type of pain experienced after laparoscopy differs from that experienced after laparotomy, it is predominantly…
- Trial name
- NCT06663345
- Testing
- Transversus Abdominis Plan Block (TAPB), Lateral Quadratum Lumborum (QLB-1) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Laparoscopic Cholecystectomy, Modified Thoracoabdominal Nerve Block
Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumborum Block for Postoperative Analgesia in Laparoscopic Cholecystectomy
This study aims to compare the efficacy of using Ultrasound guided modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) versus quadratus lumborum block for postoperative analgesia in laparoscopic…
- Conditions
- Laparoscopic Cholecystectomy, Modified Thoracoabdominal Nerve Block, Quadratus Lumborum Block
- Trial name
- NCT06588777
- Testing
- Modified thoracoabdominal nerve block through perichondrial approach (M-TAPA), Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Pain
Ketamine Irrigation Analgesia in Laparoscopic Cholecystectomy
Patients will be assigned randomly to two groups (30 subjects each) to be anesthetized. The study drug will be delivered in opaque bags labeled "study drug" and 60 patients will be allocated in two groups (of 30 patients each) to…
- Trial name
- Ketamine (NCT07370181)
- Testing
- Normal saline, Ketamine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postmastectomy Pain
SPSIP Block in Breast Surgeries for Postoperative Analgesia
The aim of this clinical study is to demonstrate that pain following breast surgeries can be reduced through the application of serratus posterior superior intercostal plane block (SPSIPB).
- Trial name
- SPSIPB (NCT06100419)
- Testing
- serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Postoperative Pain, Thoracic Surgery
Analgesia With Transdermal Buprenorphine Patch in Adults Undergoing Video-Assisted Thoracoscopic Surgery
Postoperative pain remains a major challenge after video-assisted thoracoscopic surgery (VATS), despite the use of multimodal analgesia.
- Conditions
- Postoperative Pain, Thoracic Surgery, Video-Assisted Thoracoscopic Surgery
- Trial name
- NCT07733128
- Testing
- Buprenorphine (BUP)
- Where
- Chile
- Volunteers
- 90 people
- Sponsor
- Clínica Dávila
Postoperative Pain
Safety and Efficacy of Patient Controlled Analgesia Using the Sublingual Sufentanil Tablet System (SSTS) in a Fast Track Rehabilitation Program After Total Knee Arthroplasty
The sufentanil sublingual tablet system (SSTS) is an innovative patient-controlled analgesia (PCA) device for the management of acute moderate to severe postoperative pain in hospital settings in adult patients.
- Trial name
- Zalviso (NCT04432428)
- Testing
- Sufentanil Sublingual Tablet
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- University Hospital, Ghent
Pain, Postoperative, Spinal Disease
Comparison of Ultrasound-guided Bilateral ESP Block and Wound Infiltration for Spinal Surgical Analgesia
The aim of our study is to determine the superior procedure in analgesia management by comparing the traditional wound infiltration technique with the ultrasound-guided bilateral erector spina plan block technique in spinal…
- Conditions
- Pain, Postoperative, Spinal Disease, Anesthesia, Local, Anesthesia, Regional
- Trial name
- NCT04642625
- Testing
- Visual Analog Score, patient satisfaction
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
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