Clinical trials: Analgesia, Postoperative
Hip Osteoarthritis, Pain, Acute
Lumbar Plexus and Suprainguinal Fascia Iliaca Blocks For Total Hip Replacement
The nerves from lumbar plexus (LP) are the current target to achieve analgesia after a total hip arthroplasty (THA). Lumbar plexus block (LPB) is an alternative that provides optimal postoperative analgesia.
- Conditions
- Hip Osteoarthritis, Pain, Acute, Pain, Postoperative, Opioid Use
- Trial name
- NCT03744065
- Testing
- lumbar plexus block, suprainguinal fascia iliaca block
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Anesthesia
Intraperitoneal Bupivacaine With Magnesium or Nalbuphine for Postoperative Pain Control in Laparoscopic Hysterectomy
The purpose of this study is to compare between the addition of Mg sulphate or Nalbuphine to intraperitoneal bupivacaine installation in laparoscopic hysterectomy for postoperative pain control and their relative adverse effects.
- Trial name
- NCT03393572
- Testing
- Bupivacaine 0.25%, Magnesium sulphate., nalbuphine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Pain, Postoperative, Healing Wound
Evaluation of the Effects of Medicaments Used After Free Gingival Graft on Postoperative Complications.
In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting (FGG).
- Conditions
- Pain, Postoperative, Healing Wound, Hemorrhage, Analgesia
- Trial name
- NCT05386667
- Testing
- Majezik %0.25 oral spray, Aftamed oral spray, Crystalin oral spray
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Open Colorectal Surgery, Early Rehabilitation After Surgery
Continuous Preperitoneal Infusion of Local Anesthetic (CPA) Versus Epidural Infusion of Local Anesthetic (EA) in Fast-Track Open Colorectal Surgery
The purpose of this study is to compare the continuous preperitoneal infusion of local anesthetic and continuous epidural analgesia for postoperative pain management in fast-track open colorectal surgery.
- Trial name
- NCT00915265
- Testing
- Multilobed catheter (group CPA), Multilobed catheter (group EA)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Perioperative Pain Management
Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative Pain and Incidence of Postoperative Chronic Pain Within ERAS Protocols, a Dose Finding Study.
This study aimed To investigate the effects of different doses of Intraoperative intravenous lidocaine infusion on intraoperative opioid consumption, perioperative pain control and incidence of postoperative chronic pain.
- Trial name
- NCT06431165
- Testing
- Lidocaine IV
- Where
- Egypt
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia, Anesthesia, Local
Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children
Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM).
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia, Pediatric ALL
- Trial name
- NCT05233683
- Testing
- Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Saud University
Postoperative Pain
A Comparison Study Between Ketamine Versus Tramadol for Pain Management After Major Upper Abdominal Surgery
The purpose of the study is the comparison between ketamine and tramadol, regarding the analgesia quality and efficiency, in patients receiving Patient Controlled Analgesia (PCA) morphine, after major upper abdominal surgeries…
- Trial name
- NCT02499341
- Testing
- Tramadol, Ketamine
- Where
- Greece
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Attikon Hospital
Opioid Analgesia, Pain, Postoperative
The Effect of Tap Block in Pain Relief in Pediatric Patients
TAP block applied for analgesic purposes in pediatric patients undergoing appendectomy surgery provides superior analgesia in analgesic relief in the first 24 hours postoperatively compared to the placebo-control group without…
- Conditions
- Opioid Analgesia, Pain, Postoperative, Pain Score Reduction
- Trial name
- NCT06812169
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arnavutkoy State Hospital
Postoperative Analgesia, Postoperative Complications
Dexmedetomidine Versus Dexamethasone With Levobupivacaine in Interscalene Block
The investigators compared between dexamethasone and dexmedetomidine when added to levobupivacaine in the quality and duration of ultrasound-guided interscalene block during shoulder arthroscopy.
- Trial name
- IBBB (NCT03940469)
- Testing
- Saline, Dexamethasone Injection, Dexmedetomidine Hydrochloride
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Pain, Hypospadias
Dexmedetomidine Infusion and Surgical Pleth Index In Pediatrics
This non-invasive dimensionless score index -SPI-reflects the Patients' sympathetic response to surgical stimulation. Its effectiveness in detecting the balance between nociceptor activation and analgesia was not only reported…
- Trial name
- NCT05727969
- Testing
- Dexmedetomidine, Lactated Ringer, Hypospadias
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Postoperative Analgesia, Cesarean Section
Postoperative Analgesia After Cesarean Section; Comparison Among Ultrasound Guided Erector Spinae, Quadratus Lumborum or Transversus Abdominis Plane Blocks
The aim of this prospective randomized controlled study is to compare the analgesic efficacy of the ultrasound-guided erector spinae plane block, ultrasound-guided quadratus lumborum plane block, and ultrasound-guided transversus…
- Conditions
- Postoperative Analgesia, Cesarean Section, Erector Spinae Block, Quadratus Lumborum Block
- Trial name
- NCT06451354
- Testing
- Erector spinae plane block (20 ml bupivacaine 0.25% in each side), Posterior Quadratus lumborum plane block (20 ml bupivacaine 0.25% in each side), Lateral Transversus abdominis plane block (20 ml bupivacaine 0.25% in each side)
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Kafrelsheikh University
Ankle Arthritis, Ankle Arthropathy
Peripheral Nerve Block Compared to Intra-articular Injection for TAA Post-operative Pain
Ankle arthritis is associated with debilitating pain and chronic disability. For the treatment of severe ankle arthritis, total ankle arthroplasty (TAA) is one treatment option.
- Trial name
- NCT03674905
- Testing
- Intra-articular injection, Peripheral nerve block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Slocum Research & Education Foundation
Shoulder Arthroscopic Surgery
Erector Spinae Plane Block Versus Infraspinatus-Teres Minor Interfascial Plane Block for Analgesia After Shoulder Arthroscopy
The shoulder, being an anatomical region innervated by different nerves, has a wide variety of analgesic approaches, which differ depending on the practitioner.
- Trial name
- NCT07688395
- Testing
- cervical erector spinae plane block, Infraspinatus Teres Minor Interfascial Plane Block, Bupivacaine %0.25 (isobaric)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Solitary Mass, Lung Diseases
Comparison for Pethidine Requirement in Patients Received Spinal Morphine 0.2 and 0.3 mg for Post Lobectomy Analgesia
The purpose of the study is to evaluate the amount of total pethidine requirement during the 48 hour postoperative period after receiving spinal morphine 0.2 and 0.3 mg.
- Trial name
- pain (NCT01236495)
- Testing
- spinal morphine 0.3 mg, spinal morphine 0.2 mg
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Pain, Postoperative
Erector Spinae Plane Block Analgesia for Lumbar Spine Fusion Surgery
The purpose of this study was to investigate the effect of a bilateral ultrasound guided erector spinae plane block on the pain scores and opoid utiliziation in fusion surgery of the lumbar spine.
- Trial name
- NCT04749095
- Testing
- Erector spinae plane block
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Benha University
Post Operative Analgesia, Bradycardia
Comparative Analysis Of Dexmedetomidine And Dexamethasone As An Adjuvant To 0.5%Ropivacaine On Onset Of Ultrasound Guided Supraclavicular Brachial Plexus Block In Patients Undergoing Upper Limb Surgeries
To compare the efficacy of dexmedetomidine and dexamethasone as an adjuvant to 0.5%ropivacaine on onset of ultrasound guided supraclavicular brachial plexus block in patients undergoing upper limb surgeries.
- Conditions
- Post Operative Analgesia, Bradycardia, Hypotension, Upper Limb Surgeries
- Trial name
- NCT07290595
- Testing
- Ropivacaine + Dexmedetomidine, Ropivacaine + dexamethasone
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Postoperative Pain
Sufentanil Sublingual Tablet System for Postoperative Pain Management After Total Knee Arthroplasty
The aim of this study is to assess the effectiveness of Sublingual Sufentanil Tablets System (SSTS, Zalviso ®) to control postoperative pain after total knee arthroplasty in the context of early rehabilitation program.
- Trial name
- NCT04448457
- Testing
- Sufentanil Sublingual Tablet, Oxycodone oral tablet and oxycodone extended-release oral tablet
- Where
- Belgium
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire de Tivoli
Anterior Cruciate Ligament Injuries, Postoperative Pain
Multimodal Analgesia vs. Femoral Block in ACL Surgery
This study aims to compare the effects of a preemptive multimodal intravenous analgesia protocol and a femoral triangle block on early postoperative rehabilitation compliance in patients undergoing anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Postoperative Pain, Pain, Postoperative
- Trial name
- MAPvsFTB (NCT06936995)
- Testing
- Preemptive Multimodal Intravenous Analgesia, Femoral Triangle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ankara University
Abdominoplasty, Perioperative Analgesia
Combined Ultrasound Guided Bilateral Rectus Sheath and Erector Spinae Plain Blocks Versus Erector Spinae Plain Block for Intra and Postoperative Analgesia in Elective Abdominoplastic Surgeries. a Randomized Controlled Double Blinded Trial.
The goal of this clinical trail is to determine if bilateral erector spinae plane block alone can provide good perioperative analgesia for abdominoplastic surgery patients or it is better to give combined bilateral rectus sheath…
- Trial name
- NCT06765772
- Testing
- Erector spinae plane block, Rectus sheath block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Post Operative Analgesia, Dexmedetomidine
Comparison of Post Operative Analgesia in Patients Undergoing Lower Abdominal Surgeries Receiving Ultrasound Guided Block With Dexmetomidine vs Dexmethasone
Lower abdominal surgeries cause significant pain and can be managed by injecting local anesthetic agents between muscles of abdominal wall that can provide post operative pain relief and its duration can be prolonged by adding…
- Conditions
- Post Operative Analgesia, Dexmedetomidine, TAP Block
- Trial name
- NCT07508202
- Testing
- Dexmedetomidine, Dexamethasone
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
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