Clinical trials: Analgesia, Postoperative
Pain Postoperative, Total Knee Anthroplasty
Comparative Analgesic Effect After Total Knee Arthroplasty Between Intraosseous and Peri-articular Injection
The goal of this RCT is to compare analgesic effect after total knee arthroplasty between intraosseous multimodal analgesic agent injection versus periarticular injection.
- Conditions
- Pain Postoperative, Total Knee Anthroplasty, Functional Outcomes
- Trial name
- NCT06800846
- Testing
- Intraosseous Morphine, Periarticular Injection
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Thammasat University Hospital
Pain, Postoperative
Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery
Participants who have a surgical procedure called Posterior Cervical (neck) Spine Surgery will normally need pain medication to relieve post operative pain. This usually includes opioid medications.
- Trial name
- NCT06570577
- Testing
- Inter-semispinalis Plane Block, Opioids
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Postoperative Pain, Nerve Block
Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block on Perioperative Analgesia Management in Patients Scheduled for Mastectomy
This study aims to evaluate and compare the analgesic efficacy of two ultrasound-guided regional anesthesia techniques, the serratus anterior plane (SAP) block and the serratus posterior superior intercostal plane (SPSIP) block…
- Conditions
- Postoperative Pain, Nerve Block, Mastectomy, Patient Outcome Assessment
- Trial name
- NCT07510269
- Testing
- SAP Block, SPSIP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Uludag University
Pain, Postoperative
Bupivacaine Hydrochloride for Pain Control in Cutaneous Surgery
The purpose of this study is to determine if the addition of bupivacaine HCl injections will improve pain control after skin surgery. This is a randomized clinical trial.
- Trial name
- NCT04260854
- Testing
- Bupivacaine Hydrochloride, Saline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Ankle Arthritis, Ankle Arthropathy
Peripheral Nerve Block Compared to Intra-articular Injection for TAA Post-operative Pain
Ankle arthritis is associated with debilitating pain and chronic disability. For the treatment of severe ankle arthritis, total ankle arthroplasty (TAA) is one treatment option.
- Trial name
- NCT03674905
- Testing
- Intra-articular injection, Peripheral nerve block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Slocum Research & Education Foundation
HİP FRACTURE, Hip Surgery (Lateral Incision)
Perioperative Analgesic Effects of PENG Versus PENG Plus LFCN Block in Hip Surgeries
This study is designed to find the best way to control pain after hip surgery performed through a side (lateral) incision. Two different types of nerve blocks used before the operation will be compared.
- Conditions
- HİP FRACTURE, Hip Surgery (Lateral Incision), Postoperative Pain Management, Analgesia, Postoperative
- Trial name
- NCT07329829
- Testing
- Pericapsular nerve group (PENG) block, Lateral Femoral Cutaneous Nerve (LFCN) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Laparoscopic Cholecystectomy, Post Operative Analgesia
Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic Cholecystectomy
This study aims to compare the level of postoperative pain experienced by patients undergoing laparoscopic cholecystectomy with and without the use of intraperitoneal bupivacaine.
- Conditions
- Laparoscopic Cholecystectomy, Post Operative Analgesia, Bupivacaine
- Trial name
- BUPA-LC (NCT07098429)
- Testing
- Bupivacain (Postoperative), Normal (0.9%) saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh
Anesthesia and Analgesia, Anesthesia, Endotracheal
Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery
Anesthesia without the use of opioid (Opioid free anesthesia) is an alternative to conventional opioid balanced anesthesia, with less post operative nausea and vomiting, and comparable analgesia.
- Trial name
- NCT06382831
- Testing
- Dexmedetomidine, Fentanyl
- Volunteers
- 104 people
- Sponsor
- Universitas Indonesia
Pain, Acute Post-Operative, Pilonidal Sinus
Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery
Introduction: This study investigated the efficacy of sacral erector spinae plane block (ESPB) for managing postoperative pain and reducing opioid consumption in patients undergoing hemorrhoid and pilonidal sinus (PS) surgery.
- Conditions
- Pain, Acute Post-Operative, Pilonidal Sinus, Hemorrhoids, Anesthesia
- Trial name
- NCT06459739
- Testing
- sacral ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Total Knee Anthroplasty
Genicular Nerve Block Added to Femoral Nerve Block for Analgesia After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a common orthopedic procedure in which effective postoperative pain management is important for early mobilization and rehabilitation.
- Trial name
- GNB-FNB (NCT07478783)
- Testing
- Ultrasound-guided Femoral Nerve Block, ltrasound-guided Genicular Nerve Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Effect of RECK in Posterior Spinal Fusion
"RECK" is a combination of local anesthesia medications, used for the purpose of pain control. RECK is an acronym which stands for Ropivacaine, Epinephrine, Clonidine, and Ketorolac.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
- Trial name
- NCT06447194
- Testing
- Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Post-operative Pain Control
Impact of the Number of Opiates Prescribed on Post Cesarean Pain Control
The purpose of this randomized trial is to examine whether the number of opioid pills prescribed for pain control after Cesarean section has an effect on patient reported pain levels and satisfaction with pain control during…
- Trial name
- NCT03175653
- Testing
- Oxycodone Pill A, Oxycodone Pill B
- Where
- United States
- Sponsor
- Mount Carmel Health System
Postoperative Pain
Transversus Abdominis Plane Block Versus Ilioinguinal-Iliohypogastric Nerve Block for Postoperative Analgesia Following Open Total Abdominal Hysterectomy
The investigators hypothesised that ultrasound-guided transversus abdominis plane (TAP) block would prolong the time to first rescue nalbuphine within 24 hours compared with ultrasound-guided ilioinguinal-iliohypogastric (IIH)…
- Trial name
- NCT05656872
- Testing
- Transverse Abdominis Plane Block, Ilioinguinal-iliohypogastric block
- Where
- 2 sites in Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Post Operative Pain, Analgesia
Ultrasound Guided Erector Spinae Plane Block Versus Retrolaminar Plane Block
Retrolaminar block (RLB) and erector spinae plane block (ESPB) are alternative approaches to paravertebral block (PVB) and are advantageous in that they are easier and safer techniques compared with the traditional PVB.
- Trial name
- NCT05705739
- Testing
- retrolaminar block, ESPB
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Minia University
Postoperative Analgesia, Cesarean Delivery
Comparison of Two Dosing Regimens of Intravenous Ketorolac for Post-Cesarean Pain Control
we aim to compare the analgesic efficacy of two intravenous ketorolac dosing regimens as part of a multimodal analgesic protocol that includes local wound infiltration for postoperative pain management after elective cesarean…
- Conditions
- Postoperative Analgesia, Cesarean Delivery, Ketorolac
- Trial name
- NCT07244757
- Testing
- Ketorolac 30 mg, Ketorolac 15mg
- Where
- Egypt
- Volunteers
- 125 people
- Sponsor
- Cairo University
Pain
Assessment of Pain Monitoring With ANI/NIPE Monitor Program in Pediatric Cardiac Surgery Postoperative.
The main objective is to assess correlation between ANI/NIPE values and external evaluation COMFORT B scale during painful medical cares and during said comfort medical cares in intubated children admitted in pediatric intensive…
- Trial name
- ANI/NIPE (NCT02834481)
- Testing
- ANI/NIPE
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Pain, Postoperative
Postoperative Pain Treatment in Total Hip Arthroplasty: A Study to Assess the Effect of Local Analgesia
The purpose of this study is to determine whether the investigator standardized pain treatment plus local pain treatment is more effective than the investigator standardized pain treatment plus placebo in total hip arthroplasty.
- Trial name
- NCT00603083
- Testing
- Ropivacaine, Ketorolac and Adrenalin
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Vejle Hospital
Pain Management
Regional Block for Postoperative Free Flap Care
The purpose of this protocol is to evaluate the safety and efficacy of regional anesthesia for head and neck patients undergoing microvascular free flap reconstruction.
- Trial name
- NCT04080739
- Testing
- ropivicaine 0.2%
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Arthroplasty, Replacement, Hip
Intraarticular Analgesia After Total Hip Arthroplasty, a Randomised Study
The purpose of this study is to determine whether wound infiltration with following single-shot bolus injection with local anesthetic and NASIDs are effective in the treatment of postoperative pain after total hip replacement…
- Trial name
- NCT00289419
- Testing
- Epidural Ropivacaine, morphine, Ropivacaine, Ketorolac and Adrenaline
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Pain, Postoperative
Dipyrone Versus Acetaminophen in the Control of Postoperative Pain
Adequate postoperative pain management is challenging for practitioners despite recent advances in pain control techniques and analgesic agents.
- Trial name
- NCT00841841
- Testing
- dipyrone and acetaminophen
- Volunteers
- 30 people
- Sponsor
- University Center of Araraquara
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