Clinical trials: Analgesia, Postoperative
Postoperative Analgesia
Erector Spinae Muscle Block Versus Caudal Block by Sonar in Pediatrics Undergoing Lower Abdominal Surgery
this prospective randomized double blind controlled study was conducted on 60 child scheduled for lower abdominal surgery under general anesthesia.
- Trial name
- NCT04690894
- Testing
- erector spinae block - caudal block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Post Operative, Post Operative Analgesia
Postoperative Tizanidine Use in Pelvic Reconstructive Surgery: A Pilot Study
The goal of this clinical trial is to evaluate whether adding tizanidine to the standard postoperative pain regimen improves recovery after pelvic reconstructive surgery in adult women.
- Conditions
- Post Operative, Post Operative Analgesia, Urogynecologic Surgery
- Trial name
- TIPS (NCT07766837)
- Testing
- Tizanidine, Standard-of-Care Therapy
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Hartford Hospital
Pain, Acute Postoperative, Trauma Injury
Patient-Titrated Automated Intermittent Boluses of Local Anesthetic vs. a Continuous Infusion Via a Perineural Catheter for Postoperative Analgesia
This will be a randomized comparison of continuous local anesthetic infusion with patient controlled boluses (PCA) to patient-titratable automated boluses with patient controlled boluses (PCA) for both infraclavicular and…
- Trial name
- NCT05091905
- Testing
- Continuous Infusion of ropivacaine 0.2%, Titratable Automated Intermittent Boluses of ropivacaine 0.2%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Breast Cancer, Postoperative Pain
PECS Block in Partial Mastectomy for Postoperative Pain Control
The aim of this study is to evaluate patients who are undergoing partial mastectomy or removal of breast tissue and see if a pectoralis nerve block (PECS) can provide a meaningful improvement in postoperative pain control over…
- Conditions
- Breast Cancer, Postoperative Pain, Opioid Use, Local Anesthesia
- Trial name
- PECS (NCT04086394)
- Testing
- Pectoral Nerve Block, Surgery without Nerve Block
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Main Line Health
Postoperative Analgesia
Comparison of Two Different Methods for Reducing Pain After Lung Surgery
The goal of this clinical study is to compare the effectiveness of the Rhomboid Intercostal Block and Sub-Servitus plan block and the effectiveness of the Rhomboid intercostal block in patients with video-supported thoracoscopic…
- Trial name
- NCT06260137
- Testing
- Rhomboid intercostal block, Rhomboid intercostal and subserratus plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uludag University
Cervical Cancer, Endometrial Cancer
Epidural Analgesia or Patient-Controlled Analgesia in Treating Patients Who Have Undergone Surgery for Gynecologic Cancer
RATIONALE: Giving pain medication into the space between the wall of the spinal canal and the covering of the spinal cord or giving it into a vein may help lessen pain caused by cancer surgery.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00295945
- Testing
- fentanyl citrate, hydromorphone hydrochloride, ropivacaine hydrochloride
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of California, San Francisco
Hypertension
Relationship of Essential Hypertension and Its Treatments on the Postoperative Pain Management: a Prospective, Observational, Cross-sectional Study
Numbers of postoperative PCA related side effects among three groups will be determined by comparing and analyzing frequency distributions.
- Trial name
- NCT02244177
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Catheter-related Bladder Discomfort
CATHETER ANALGESIA TRIAL Phenazopyrdine vs. Placebo: a Randomized Controlled Trial
The primary aim of this randomized clinical trial is to compare the utility of phenazopyridine HCl vs. placebo in reducing catheter-associated discomfort during the post-operative period in the gynecologic patient using mean VAS…
- Trial name
- CATH (NCT00771173)
- Testing
- phenazopyridine HCl
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Loyola University
Postoperative Analgesia
Duration of Postop Analgesia After Inguinal Hernia Surgery Treated with TAP Block Vs II/IH Nerve Block
Comparing Postop Analgesia after Inguinal Hernia Surgery treated with TAP Block Vs Ilioinguinal/ Iliohypogastric Nerve Block
- Trial name
- NCT06812741
- Testing
- Transversus abdominis plane (TAP) block with 0.25 % bupivacaine, Ilioinguinal/iliohypogastric Nerve Block with 0.25 % bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Pakistan Navy Station Shifa Hospital
Enhanced Recovery After Surgery, Multimodal Analgesia
Enhanced Recovery After Surgery-Based Multimodal Preemptive Analgesia for Perioperative Management in Transarterial Chemoembolization of Intermediate-to-Advanced Hepatocellular Carcinoma
To evaluate the effectiveness of the combination of hydrochloride hydromorphone and flurbiprofen ester for post-TACE intravenous patient-controlled intravenous analgesia (PCIA).
- Conditions
- Enhanced Recovery After Surgery, Multimodal Analgesia, Real-world Study, Transarterial Chemoembolization
- Trial name
- NCT07315022
- Testing
- hydrochloride hydromorphone + flurbiprofen axetil, conventional analgesia
- Where
- China
- Volunteers
- 129 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Tramadol, Nalbuphine
Nalbuphine Versus Tramadol on Post Operative Analgesia in Abdominal Surgery on Pediatric Cancer Patient
In current study the investigators aim to compare between nalbuphine versus tramadol for post-operative pain control in abdominal surgeries in pediatric.
- Conditions
- Tramadol, Nalbuphine, Abdominal Surgeries, Pediatric Cancer
- Trial name
- NCT07110051
- Testing
- Nalbuphine, Tramadol
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- National Cancer Institute, Egypt
Postoperative Pain, Cardiac Surgery
Parasternal vs. Combined Parasternal-Serratus Block in Cardiac Surgery
This randomized controlled trial aims to compare the analgesic efficacy of parasternal intercostal plane block (PIPB) alone versus the combination of parasternal intercostal plane block and serratus anterior plane block (SAPB) in…
- Trial name
- Hanedan Block (NCT07522229)
- Testing
- Parasternal Intercostal Plane Block, Parasternal Intercostal Plane Block + Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- BEDİA MİNE HANEDAN
Postoperative Pain, Cholecystectomy, Laparoscopic
Recto-Intercostal Fascial Plane and External Oblique Intercostal Blocks for Pain in Laparoscopic Cholecystectomyin Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is a common surgical procedure that can cause significant postoperative pain, particularly originating from trocar insertion sites.
- Trial name
- NCT07777172
- Testing
- Group EOIPB (External Oblique Intercostal Plane Block), Group EOIPB + RIFPB (Combined Blocks)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Analgesia
Fentanyl Versus Midazolam as an Adjunct to Intrathecal Bupivacaine In Children
The primary aim of the present study will be to compare the analgesic effect of addition of fentanyl or midazolam to intrathecal bupivacaine by using CHEOPS pain score (Children's Hospital Eastern Ontario Pain Scale) which is…
- Trial name
- NCT03592537
- Testing
- Fentanyl, Midazolam, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Transurethral Resection of Prostate
Effectiveness of Nalbuphine as an Adjuvant to Subarachnoid Block on Postoperative Analgesia in TURP Surgery
The goal of this clinical trial is to compare pain after surgery in patients undergoing Transurethral Resection of Prostate. The main question it aims to answer are: Intrathecal nalbuphine as an adjuvant to local anesthetic will…
- Trial name
- NCT06153602
- Testing
- Nalbuphine Hydrochloride 10 MG/ML, Sodium Chloride 0.9 % in 5 ML Injection, Bupivacaine Hydrochloride, Spinal
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Chulalongkorn University
Breast Cancer Surgery, Breast Cancer Surgery Pain
Impact of High Thoracic Paravertebral Block on Diaphragmatic Function: a Prospective Study
The high thoracic paravertebral block is a regional anesthesia technique commonly used for oncologic breast surgery. Local anesthetic is injected into the paravertebral space to provide anesthesia and pain relief.
- Conditions
- Breast Cancer Surgery, Breast Cancer Surgery Pain, Hemidiaphragmatic Paralysis
- Trial name
- NCT07907692
- Testing
- High thoracic paravertebral block
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Postoperative Pain Management After Total Hip Arthroplasty
Treatment of Postoperative Pain After Total Hip Arthroplasty Using Intravenous Lidocaine Infusion
This study will focus on patients undergoing total hip arthroplasty and Loma Linda University Medical Center \& East Campus. These patients will be randomized to receive a low dose lidocaine infusion or placebo, in addition to…
- Trial name
- NCT01108562
- Testing
- Lidocaine, Normal Saline
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Anesthesia
Erector Spinae Plane Block Versus Quadratus Lumborum Block For Postoperative Analgesia After Abdominal Hysterectomy
The aim of this study is to compare the analgesic efficacy of erector spinae plane block and quadratus lumborum block after abdominal hysterectomy surgery and postoperative opioid consumption.
- Trial name
- NCT05541588
- Testing
- peripheral nerve block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Anesthesia
Intraperitoneal Bupivacaine With Magnesium or Nalbuphine for Postoperative Pain Control in Laparoscopic Hysterectomy
The purpose of this study is to compare between the addition of Mg sulphate or Nalbuphine to intraperitoneal bupivacaine installation in laparoscopic hysterectomy for postoperative pain control and their relative adverse effects.
- Trial name
- NCT03393572
- Testing
- Bupivacaine 0.25%, Magnesium sulphate., nalbuphine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Post-operative Pain, Sinus Surgery
Postoperative Pain Control in Septum and Sinus Surgery
This study will evaluate if the use of acetaminophen round the clock (scheduled doses) will lead to less opiate use in the first week post-operative (after surgery) in sinus/septum surgery patients.
- Trial name
- NCT04149964
- Testing
- Acetaminophen 325 mg Oral Tablet, Acetaminophen 650 mg Oral Tablet, OxyCODONE 5 mg Oral Tablet
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Corewell Health East
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