Clinical trials: Analgesia, Postoperative
Pain, Postoperative
Serratus Planus Block After Minimally Invasive Cardiac Surgery
Many patients receiving MICS (minimally invasive cardiac surgery) suffer from significant postsurgical pain. While systemic analgesic therapy has been proven to be insufficient in a great number of patients, significant unwanted…
- Trial name
- NCT06746272
- Testing
- Serratus Anterior Plane Block
- Where
- Austria
- Volunteers
- 66 people
- Sponsor
- Medical University of Vienna
Pain Postoperative
OSTAP Versus TAP for Postoperative Pain Management in Laparoscopic Cholecystectomy Patients
The aim of the study is to compare the effectiveness and opioid sparing effects of TAP and OSTAP in patients undergoing laparoscopic cholecystectomy.
- Trial name
- OSTAP/TAP (NCT03954795)
- Testing
- TAP, OSTAP
- Volunteers
- 75 people
- Sponsor
- Balikesir University
Postoperative Pain
Comparison of Quadratus Lumborum Block and Epidural Analgesia Following Kidney Transplant Surgery
Quadratus lumborum block as an alternative for postoperative analgesia compared with epidural block
- Trial name
- NCT03771339
- Testing
- Continuous Epidural analgesia, Bilateral Quadratus Lumborum block
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
POSTOPERATIVE PAIN
Comparative Study of Two Different Techniques to Perform TAP-blocks
The TAP is a space between the muscle layers of the abdominal wall that houses nerves supplying the abdominal skin. Injecting the local anesthetic ropivacaine into this space will block these nerves and prevent pain following…
- Trial name
- Surgical-TAP (NCT02571439)
- Testing
- Surgical TAP block, Conventional TAP block, 0.5% ropivacaine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Maimonides Medical Center
Breast Cancer
Comparative Evaluation of Pectoral Nerve Block Type II Versus Rhomboid Intercostal and Subserratus Plane Block in Breast Cancer Mastectomy for Postoperative Analgesia: a Randomized, Controlled Trial
This study aimed to investigate the analgesic effects of Pectoral Nerve Block Type II and Rhomboid Intercostal and Subserratus Plane Block after radical mastectomy for breast cancer.This prospective, double-blind, randomized…
- Trial name
- NCT06760429
- Testing
- Pectoral Nerve Block Type II, Subserratus Plane Block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Inner Mongolia Baogang Hospital
Pain
TAP Block Alone Versus TAPblock With Rectus Sheath Block in Liposuction Surgery
The transversus abdominis plane (TAP) block is an effective regional nerve block for the anterior abdominal wall. An anesthesiologist typically administers the TAP block preoperatively with ultrasound guidance.
- Trial name
- NCT02854553
- Testing
- Transversus abdominis plane block, rectus sheath block
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Postoperative Analgesia, Postoperative Pain Management
Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia
In this study the participants aim to Compare The Effect of Intravenous Combination Dexmedetomidine _ Ketamine versus Dexmedetomidine on Post-Operative Analgesia In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia regarding…
- Trial name
- NCT07330375
- Testing
- Dexmedetomidine, Ketamine, Saline (0.9% NaCl)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain
Analgesic Effect of Superficial Cervical Plexus Block in Postoperative Neck Surgeries
analgesic effect of superficial cervical plexus block by using ultrasound in patients undergoing neck surgeries
- Trial name
- NCT07539935
- Testing
- superficial cervical plexus block guided by ultrasound with bupivacaine, Paracetamol (500 mg) tablets
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Postoperative Pain Following Knee Arthroplasty
Evaluating Suzetrigine for Pain Control Following TKA
The goal of this clinical trial is to learn if a non-opioid pain medicine called suzetrigine works to treat pain after total knee replacement surgery in adults. It will also learn about the safety of suzetrigine.
- Trial name
- NCT07357376
- Testing
- Suzetrigine
- Volunteers
- 210 people
- Sponsor
- AdventHealth
Postoperative Pain
Effect of Posterior Femoral Cutaneous Nerve Block on Postoperative Posterior Lateral Knee Analgesia in Patients With TKA
The aim of this study was to observe the effects of posterior femoral cutaneous nerve block combined with sciatic and saphenous nerve block compared with sciatic and saphenous nerve block alone on postoperative posterior side of…
- Trial name
- NCT06522620
- Testing
- Posterior Femoral Cutaneous Nerve Combined With Proximal Sciatic and Saphenous Nerve Block, Simple Sciatic and Saphenous Nerve Blocks
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Acute Pain
A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery
This is a single-center, randomized, double blind, placebo controlled, parallel group proof of concept study to evaluate the analgesic efficacy as well as the safety, tolerability and pharmacokinetic profile of CR845 in patients…
- Trial name
- NCT01789476
- Testing
- CR845
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Cara Therapeutics, Inc.
Disease Status of Pancreatobiliary Tract , ( Especially Who Need to Undergo Pancreaticoduodenectomy)
Postoperative Muscular Pain, ETOIMS (Electrical Twitch Obstructive Intramuscular Stimulation)
Pancreaticoduodenectomy is inevitably an operation requiring extensive skin and muscle incision, resulting in postoperative pain resulting in limitation of the patient's early exercise and function.
- Trial name
- NCT03619343
- Testing
- ETOIMS(Electrical Twitch Obtaining Intramuscular Stimulation)
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Yonsei University
Hemorrhoids, Fissure in Ano
Pre-Emptive Analgesia in Ano-Rectal Surgery
The perianal region is the region around the anus. Administering a pain medication before a surgery starts is called preemptive analgesia.
- Conditions
- Hemorrhoids, Fissure in Ano, Rectal Fistula, Anal Condyloma
- Trial name
- PEAARS (NCT02402543)
- Testing
- Gabapentin, Ketamine, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Vermont
Preoperative Anxiety, Postoperative Delirium
Preoperative Anxiety and Preemptive Analgesia on Postoperative Delirium in Adenotonsillectomy Surgery
The effects of preoperative anxiety and preemptive analgesia on PAED in children undergoing adenotonsillectomy surgery.
- Trial name
- NCT05802082
- Testing
- The Modified Yale Preoperative Anxiety Scale (m-YPAS) of children
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Zonguldak Bulent Ecevit University
Postoperative Pain
Flurbiprofen Axetil for Uterine Contraction Pain
Uterine contraction pain is a common problem after abortion. Optimal analgesic for such suffering is still needed to be guaranteed.
- Trial name
- FAUCOP (NCT00725218)
- Testing
- Saline, Flurbiprofen Axetil
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Nanjing Medical University
Regional Anesthesia
Retrospective Evaluation of Effect of Anterior Iliac Block
In this study, the investigators aimed to evaluate the effect of ultrasound-guided anterior iliac block which was performed preoperatively. Anterior iliac bone harvesting is associated with severe postoperative pain.
- Trial name
- NCT06295224
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Kocaeli University
Blepharoptosis
Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid
Conjunctival Mullerectomy is a well known procedure used to correct upper lid ptosis via a posterior approach. Patients who undergo this procedure are often given local anesthesia to alleviate intraoperative and postoperative…
- Trial name
- NCT01350024
- Testing
- Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine, Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
Post-surgical Pain
Hydromorphone Hydrochloride Epidural Preemptive Analgesia for Postoperative Pain After Cesarean Section
Acute pain often occurs after cesarean section, which can lead to stress and inflammatory response in the body, which will not only affect the postpartum recovery speed of the puerpera, but also inhibit the secretion of prolactin…
- Trial name
- HHEPA (NCT06823180)
- Testing
- Hydromorphone hydrochloride low dose, Hydromorphone hydrochloride high dose, 0.9% sodium chloride
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Liquan Liang
Pain, Postoperative
Addition of Muscle Relaxants in a Multimodal Analgesic Regimen for Analgesia After Primary Total Knee Arthroplasty
This is a prospective, cluster-randomized, two-arm, comparative study aimed at determining whether addition of tizanidine ( an oral muscle relaxant) to a multimodal pain regimen following primary TKA reduces opioid consumption.
- Trial name
- NCT04574791
- Testing
- TiZANidine 2 MG Oral Capsule
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Anterior Cruciate Ligament Reconstruction
Study of Pain Management Techniques Following Anterior Cruciate Ligament Repair Surgery
Patients scheduled to undergo knee arthroscopy with anterior cruciate ligament repair with graft from the ipsilateral hamstrings and gracilis will be randomized to one of three groups.
- Trial name
- NCT01868282
- Testing
- Hamstrings block, Obturator block, Control group
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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