Clinical trials: Analgesia, Postoperative
Anesthesia, Local
Liposomal Bupivacaine Versus Bupivacaine for for Postoperative Pain Control in Shoulder Surgery
This is a randomized, single blinded clinical trial whose purpose is to assess the impact of liposomal bupivacaine (LB) in a single shot interscalene nerve block compared with standard bupivacaine (same dose) in a single shot…
- Trial name
- NCT04180943
- Testing
- interscalene nerve block
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Bassett Healthcare
Total Knee Anthroplasty, Epidural Analgesia
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty
The goal of this clinical trial is to compare two different epidural analgesia delivery methods for pain control after total knee arthroplasty in adults undergoing elective surgery.
- Trial name
- NCT07605208
- Testing
- Programmed intermittent epidural bolus 6 ml, continuous epidural infusion
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sakarya University
Nerve Block
Deep Parasternal Intercostal Plane Block
Cardiac surgery is a source of severe post operative pain witch can cause major respiratory complications due to non optimal post operative rehabilitation.
- Trial name
- DPIP (NCT06895876)
- Testing
- Deep parasternal intercostal plane block
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Institute Arnault Tzanck, France
Post Operative Pain
Analgesic Effect of M-TAPA and TAPB on Laparoscopic Cholesistectomy
Cholecystectomy is the most frequently performed abdominal surgery in developed nations, with laparoscopic cholecystectomy being recognized as the gold standard technique for treating gallstones.
- Trial name
- NCT06662617
- Testing
- modified thoracoabdominal nerve block through perichondrial approach, Transversus Abdominal Plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Pain, Postoperative, Postoperative Nausea and Vomiting
Local Infiltration Analgesia With Ropivacaine Versus Placebo in Caesarean Section
The purpose of this study is to compare systematic local infiltration with Ropivacaine 0.5 % versus Ropivacaine 0.2 % versus Placebo in patients undergoing elective caesarean section.
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Cesarean Section
- Trial name
- NCT00891540
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Hvidovre University Hospital
Femoral Neck Disease
A Study of Ropivacaine Combined With Different Concentrations of Methylene Blue Fascia Iliaca Block in Postoperative Analgesia, Cognition, and Hip Function Recovery in Patients Undergoing Hip Arthroplasty
Total hip arthroplasty (THA) is a commonly used treatment for hip lesions, but it is often accompanied by persistent pain after surgery, which obviously affects the quality of life of patients, so perfect postoperative analgesia…
- Trial name
- NCT06520306
- Testing
- Ropivacaine combined with methylene blue for iliac fascia block
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Wang wanxia
Postoperative Pain
Prediction of Immediate Postoperative Pain Using Analgesia/Nociception Index (ANI)
The aim of this study is to evaluate the performance of Analgesia/Nociception Index (ANI) measured at the end of surgery for the prediction of immediate postoperative pain in postoperative care unit in adult patients undergoing…
- Trial name
- NCT01796249
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Emmanuel Boselli
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 2)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04750538
- Testing
- BreEStim 120, BreEStim 240
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- The University of Texas Health Science Center, Houston
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluation of the Use of CGF Based Sticky Bone Packed in Fresh Odontectomy Site of Impacted Lower 3rd Molars
This clinical study aims to evaluate the effectiveness of Concentrated Growth Factor (CGF)-based sticky bone in enhancing bone healing after surgical removal of impacted mandibular third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07517835)
- Testing
- Concentrated growth factors
- Volunteers
- 10 people
- Sponsor
- Cairo University
Osteo Arthritis Knee, Analgesia
Comparing Local Anesthesia With and Without iPACK Block
Total knee arthroplasty is an effective surgical intervention for patients with chronic osteoarthritis commonly performed worldwide. Postoperative pain management has been a key focus in patient care for this procedure.
- Conditions
- Osteo Arthritis Knee, Analgesia, Pain, Postoperative
- Trial name
- NCT04635176
- Testing
- Real iPACK block (20 mL of 0.25% bupivacaine, 2.5mcg/mL epinephrine, and 50mcg/mL preservative-free dexamethasone)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Injury of Foot, Shoulder or Knee, Perineural Analgesia
Postoperative Patient-controlled Perineural Analgesia After Orthopedic Surgery by "Remote Control" Versus "Bedside Care"
Perineural injection of local anesthesic is currently the reference method for the treatment of post operative pain in a patient undergoing major orthopedic surgery. Postoperative pain is a dynamic phenomena in every patient.
- Conditions
- Injury of Foot, Shoulder or Knee, Perineural Analgesia, Pain, Postoperative
- Trial name
- MICREL (NCT02018068)
- Testing
- Remote control, At bedside care
- Where
- 4 sites in France, Netherlands and 1 more
- Volunteers
- 72 people
- Sponsor
- University Hospital, Montpellier
Erector Spina Plan Block
The Effect of bılateral Erector spına Plan Block on postoperatıve paın ın spınal Surgery
Patients undergoing lumbar spinal stabilization surgery may experience severe postoperative pain lasting at least three days. Analgesia after lumbar stabilization surgery is beneficial for early recovery and is therefore…
- Trial name
- ESPB (NCT07537647)
- Testing
- UNDER ULTRASOUND GUİDANCE ESPB BLOCK, PROCEDURE/SURGERY: ERECTOR SPİNAE (ESP) BLOCK WİTH BUPİVACAİNE
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Postoperative Pain
Comparison of Two Multimodal Analgesia Regimens in Total Knee Arthroplasty
The improvement of postoperative analgesia is an important issue in orthopedic surgery, especially after total knee arthroplasty The use of a peripheral nerve block such as the adductor canal block is favored since it offers a…
- Trial name
- NCT03990038
- Testing
- Continuous perineural infusion of ropivacaine 0.2% 5 ml/h for 48 h, Extended Release Capsule
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Head and Neck Carcinoma, Hypopharyngeal Carcinoma
Intraoperative Methadone for the Management of Postoperative Pain in Patients With Head and Neck Cancers
This phase IV trial compares how well methadone plus standard fentanyl given during surgery (intraoperative) works compared to intraoperative standard fentanyl alone in managing pain after surgery (postoperative) among patients…
- Conditions
- Head and Neck Carcinoma, Hypopharyngeal Carcinoma, Laryngeal Carcinoma, Oral Cavity Carcinoma
- Trial name
- NCT07857655
- Testing
- Electronic Health Record Review, Fentanyl, Laryngoscopy
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- OHSU Knight Cancer Institute
Postoperative Pain, Mitral Valve Disease
Postoperative Analgesia After Minithoracotomy
Patients scheduled for minimally invasive mitral valve replacement. Each patient will be treated with intravenous (i.v.) oxycodone - patient-controlled analgesia (PCA).
- Trial name
- NCT03415555
- Testing
- Erector Spinae Plane blockade, Oxycodone, general anesthesia
- Where
- Poland
- Volunteers
- 19 people
- Sponsor
- Medical University of Lublin
Pain, Postoperative, Adverse Reaction to Epidural Anesthesia
Pediatric Caudal Anesthesia Block. And Pain Control
Caudal epidural block CEB is the most commonly performed neuraxial block to provide effective pain relief and analgesia in patients undergoing infra-umbilical pediatric surgery.
- Conditions
- Pain, Postoperative, Adverse Reaction to Epidural Anesthesia, Anesthesia, Caudal
- Trial name
- CEB (NCT05581940)
- Testing
- Group A Caudal Epidural Anesthesia with bupivacaine 0.25% and group B with opioid intervenors
- Where
- Bahrain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Pain, Side Effects
Comparison of IV PCA and Wound Infusion After Repair of Pectus Excavatum
Postoperative pain management is a major problem after repair of pectus excavatum.Various methods of pain management have been introduced.
- Trial name
- NCT01908491
- Testing
- IV PCA, Continuous wound infusion
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Modified Radical Mastectomy
Preemptive Erector Spinae Plane Block Versus Serratus Anterior Plane Block in MRM
Modified radical mastectomy (MRM) is one of the most performed surgeries for breast cancer. MRM is associated with significant pain during the immediate postoperative period.
- Trial name
- NCT06404918
- Testing
- Erector spinae plane group, Serratus anterior plane group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Postoperative Pain
The Difference Between the Extrafascial Injection and the Subfascial Injection of Quadratus Lumborum Block
Quadratus lumborum block can be used for the hip surgery and abdominal surgery postoperative analgesia. But the lower thoracic to the hip dermatome can't be blocked at the same time.
- Trial name
- NCT03421821
- Testing
- Ropivacaine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Third Military Medical University
Postoperative Pain
ACB Versus IA Analgesia in Knee Arthroscopy
Reconstruction of the anterior cruciate ligament (ACL) of the knee is a painful procedure, and effective postoperative analgesia is important for early return of patient activity.
- Trial name
- NCT04715152
- Testing
- ACB group, IA group
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Assiut University
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