Clinical trials: Analgesia, Postoperative
Pre- and Postoperative Analgesia, Spinal Anesthesia
Randomized Study of Spinal Anesthesia Compared With Traditional Epidural Anesthesia Concerning Peroperative and Postoperative Pain After Open Nephrectomy in Patients With Renal Cell Carcinoma
The study aim to study whether spinal anesthesia (using: bupivacain, morfin och klonidin) can be better than epidural anesthesia during and after open surgery for renal cell carcinoma.
- Conditions
- Pre- and Postoperative Analgesia, Spinal Anesthesia, Renal Cell Carcinoma
- Trial name
- ASA (NCT02030717)
- Testing
- klonidin, epidural anesthesia
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Umeå University
Opioid Consumption, Postoperative
Precision Pain Management - A Randomized Clinical Trial Assessing the Efficacy of Suzetrigine on Postoperative Analgesia Among Surgical Patients at Higher Risk for Persistent Postoperative Opioid Use (POU)
The purpose of the study is to investigate the efficacy of suzetrigine for treatment of acute postoperative pain among surgical patients identified as high risk for persistent postoperative opioid use (POU).
- Trial name
- NCT07672015
- Testing
- Suzetrigine, Standard Care (in control arm)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
Postoperative Pain Following Knee Arthroplasty
Evaluating Suzetrigine for Pain Control Following TKA
The goal of this clinical trial is to learn if a non-opioid pain medicine called suzetrigine works to treat pain after total knee replacement surgery in adults. It will also learn about the safety of suzetrigine.
- Trial name
- NCT07357376
- Testing
- Suzetrigine
- Volunteers
- 210 people
- Sponsor
- AdventHealth
Hip Injuries
Ultrasound Guided Local Infiltration Analgesia for Hip Arthroscopy
This study is being undertaken to compare the pain control using either bupivacaine versus liposomal bupivacaine. Liposomal bupivacaine can potentially provide pain relief lasting up to 72 hours while regular bupivacaine can…
- Trial name
- NCT01907191
- Testing
- liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Trinity Health Of New England
Acute Pain, Surgery
Prospective Observational Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Patients Undergoing Elective Surgical Procedures
The purpose of this study is to evaluate the effect of pharmacogenetics (PGx) guided treatment when implemented into the pre-operative process for patients undergoing bowel surgery, major urologic procedure, or major ventral…
- Trial name
- NCT02605343
- Testing
- NeuroIDgenetix Test Panel
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- AltheaDx
Shoulder Arthroscopy, Postoperative Pain
Magnesium Sulfate With Standard Combined Costoclavicular-Suprascapular Block for Pain Relief After Shoulder Arthroscopy.
This study aims to evaluate whether adding magnesium sulfate to a combined costoclavicular and suprascapular nerve block improves postoperative pain control in patients undergoing shoulder arthroscopy.
- Conditions
- Shoulder Arthroscopy, Postoperative Pain, Regional Anesthesia
- Trial name
- CCSS-Mg (NCT07798115)
- Testing
- Bupivacaine, Magnesium sulfate (MgSO4), Normal Saline (NS)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Assiut University
Postoperative Pain
Quality of Postoperative Pain Management Following Thoracic Surgery
The purpose of this study is to assess the quality of postoperative pain management in a Canadian teaching hospital following thoracic surgery.
- Trial name
- NCT01616550
- Testing
- Assessment of pain using the Brief Pain Questionnaire, Assessment of pain relief using a Verbal Numeric Scale (VNS), Assessment of patient' satisfaction with pain relief
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Analgesia, Surgery
U/S-guided Continuous Quadratus Lumborum Block III in Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is considered to be the first choice and a more conservative procedure than open stone surgery.
- Conditions
- Analgesia, Surgery, Renal Stone
- Trial name
- NCT04800302
- Testing
- Continous Quadratum Lumborum Block III, Single dose Quadratum Lumborum Block III, Intra-venous Morphine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Nazmy Edward Seif
Analgesia
Efficacy and Safety of Erector Spinal Plane Block (ESPB) for Analgesia in Laparoscopic Cholecystectomy
Purpose: to evaluate the efficacy and safety of erector spinal block (ESB) for analgesia in laparoscopic cholecystectomy（LC）. Method: This study is a randomized, single-blind, controlled clinical trial.
- Trial name
- NCT04648345
- Testing
- Erector spinal plane block
- Volunteers
- 90 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Obesity
Ibuprofen and Erector Spinae Plane Block After Laparoscopic Sleeve Gastrectomy
Laparoscopic sleeve gastrectomy (LSG) is defined as the first-step bariatric surgery for patients in the high surgical risk group.
- Trial name
- NCT04232072
- Testing
- Group ESPB, Group Ibuprofen
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Pain, Postoperative
Selective Block of the Axillary Nerve in Postoperative Pain Management
In this study the investigators wish to compare the effect of a selective axillary nerve block to placebo in patients undergoing arthroscopic shoulder surgery.
- Trial name
- NCT01463865
- Testing
- ropivacaine, Sodium chloride
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Hillerod Hospital, Denmark
Lumbar Erector Spinae Plane Block, Fascia Iliaca Block
Lumbar Erector Spinae Plane Block vs Fascia Iliaca Block vs Lumbar Plexus Block for Postoperative Analgesia for Total Hip Arthroplasty
This study aims to compare lumbar erector spinae plane block, fascia iliaca block, and lumbar plexus block for postoperative analgesia for hip surgery.
- Conditions
- Lumbar Erector Spinae Plane Block, Fascia Iliaca Block, Lumbar Plexus Block, Analgesia
- Trial name
- NCT06573931
- Testing
- Lumbar Erector Spinae Plane Block, Fascia Iliaca Block, Lumbar Plexus Block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Pectus Excavatum
Post Operative Pain Control Using Ropivacaine and the ON-Q System in the Adult Pectus Excavatum Patient
Pectus excavatum (PE) is a common chest wall deformity where the sternum is displaced posteriorly. In severe cases, surgery is performed to correct the defect.
- Trial name
- NCT01816477
- Testing
- ON-Q soaker catheter system, Epidural (ropivicaine 0.25%)
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Mayo Clinic
Pain, Postoperative
pMDT in Thoracic Surgery--------For the Baseline Investigation and Technical Preparation Stage
The risk of acute and chronic pain after thoracic surgery is high. The multi-disciplinary postoperative pain management strategy is the best way to control postoperative pain in thoracic surgery.
- Trial name
- NCT03759275
- Testing
- pMDT(Baseline Investigation)
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Peking University People's Hospital
Postoperative Pain, Opioid Dependence
PG and PK of Oxycodone to Personalize Post-op Pain Management Following Surgery in Children
Each year, in the U.S. alone, >6 million children undergo painful surgery; up to 50% of them experience significant and serious side effects with opioids and inadequate pain relief.
- Trial name
- NCT03495388
- Testing
- Oxycodone
- Where
- 2 sites in United States
- Volunteers
- 129 people
- Sponsor
- Senthil Sadhasivam
Coronary Arterial Disease (CAD), Serratus Anterior Muscle Plane Block
Comparison of the Analgesic Efficacy of Chest Wall Blocks in Coronary Artery Bypass Surgery
In this study, the analgesic effects of the Transverse Thoracic Muscle Plane Block and deep Serratus Anterior Plane versus deep and superficial Serratus Anterior Plane applications, which will be performed under ultrasound…
- Conditions
- Coronary Arterial Disease (CAD), Serratus Anterior Muscle Plane Block, Transversus Thoracis Muscle Plane Block, Postoperative Analgesia
- Trial name
- NCT06657261
- Testing
- The patient group receiving deep and superficial serratus anterior plane block, The patient group receiving a combination of deep serratus anterior plane block and transverse thoracic muscle plane block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Quadratus Lumborum Block, Iliohypogastric/Ilioinguinal Nerve Block
Comparison of Ultrasound-guided Quadratus Lumborum Block and Iliohypogastric/Ilioinguinal Nerve Block for Postoperative Pain Management in Patients Undergoing Cesarean Section
The purpose of this study is to compare the analgesic effect of ultrasound-guided quadratus lumborum block and iliohypogastric/ilioinguinal nerve block for postoperative pain management in patients undergoing cesarean section.
- Conditions
- Quadratus Lumborum Block, Iliohypogastric/Ilioinguinal Nerve Block, Cesarean Section
- Trial name
- NCT04822870
- Testing
- quadratus lumborum block, iliohypogastric/ilioinguinal nerve block, epidural analgesia
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Peking University People's Hospital
Hallux Valgus
Ultrasound Guided Single Shot Block of Posterior Tibial Nerve for Postoperative Pain Relief After Hallux Valgus Surgery
Hallux surgery is known to be extremely painful. Standard pain therapy is treatment with NSAID and opioid painkillers. Patients are frequently not-satisfied with this.
- Trial name
- Hallux (NCT02282956)
- Testing
- Ropivacaine 0,75%, posterior tibial nerve block, morphine and droperidol
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Dr.med. Sabine Schoenfeld
Hip Fractures, Pain, Postoperative
Effects of Pericapsular Nerve Group Block Applied in Patients Undergoing Hip Fracture Surgery.
In this study, it was aimed to compare the multimodal analgesia application or the pericapsular nerve group (PENG) block methods in patients undergoing hip surgery.
- Trial name
- NCT06183541
- Testing
- Pericapsular Nerve Group (PENG) Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Umraniye Education and Research Hospital
Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV)
Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery
The goal of this clinical trial is to evaluate the effectiveness of intravenous dexamethasone in preventing adverse effects of spinal anesthesia and prolonging postoperative analgesia in parturients undergoing elective cesarean…
- Conditions
- Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV), Pain, Postoperative
- Trial name
- NCT07615595
- Testing
- Dexamethasone
- Where
- Vietnam
- Volunteers
- 176 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
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