Clinical trials: Analgesia, Postoperative
Osteoarthritis
Local Infiltration Analgesia or Intrathecal Morphine in Total Knee Arthroplasty
The purpose of this study is to determine whether local infiltration analgesia is more effective than intrathecal morphine in reducing postoperative pain in total knee arthroplasty.
- Trial name
- NCT00992082
- Testing
- ropivacaine, ketorolac and epinephrine, morphine
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Enhanced Recovery After Surgery, Anesthesia
Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery
Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in Enhanced Recovery After Surgery protocol for colorectal surgery in our…
- Conditions
- Enhanced Recovery After Surgery, Anesthesia, Surgery-Complications, Colorectal
- Trial name
- NCT06065696
- Testing
- Early mobilization, No early mobilization
- Where
- Indonesia
- Volunteers
- 343 people
- Sponsor
- Universitas Indonesia
Analgesia
Effect of the Quadratus Lumborum Block Versus the Lumbar Plexus for Spiral Thighplasty Surgery
Whether trans muscular QLB provides postoperative analgesia compared with LPB after thigh lift surgery
- Trial name
- QLB&LPB (NCT07280182)
- Testing
- Ultrasound-Guided Trans-muscular QLB, Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Menoufia University
Nail Diseases
Post-op Analgesia of Nail Unit Procedures
The purpose of this study is to directly compare the efficacy of suzetrigine vs. oxycodone+acetaminophen vs. alternating acetaminophen/ibuprofen in controlling post-operative pain after the following nail unit procedures.
- Trial name
- NCT07820969
- Testing
- Suzetrigine, Oxycodone/Acetaminophen, Acetaminophen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Miami
Recurrent Tonsillitis, Obstructive Sleep Apnea
Post-operative Pain Control After Pediatric Adenotonsillectomy
Adenotonsillectomy is one of the most common surgical procedures performed in the pediatric population in the United States. It is generally a well-tolerated procedure with post-operative bleeding risk ranging from 3-5% in…
- Conditions
- Recurrent Tonsillitis, Obstructive Sleep Apnea, Sleep Disordered Breathing, Adverse Reaction to Drug
- Trial name
- NCT02296840
- Testing
- Ibuprofen, Hydrocodone-Acetaminophen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Emory University
POSTOPERATIVE ANALGESIA
PENG Block and Lateral Femoral Cutaneous Nerve Block For Hip Replacement Surgery
Background: this study aimed to describe the pain relief outcomes after hip replacement surgery by continuous Pericapsular Nerve Group Block (PENG Block) in combination with lateral femoral cutaneous nerve (LFCN) block under the…
- Trial name
- NCT06040879
- Testing
- PERICAPSULAR NERVE GROUP BLOCK COMBINED WITH LATERAL FEMORAL CUTANEOUS NERVE BLOCK
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Hanoi Medical University
Post-operative Pain
Patient Re-education vs. Background Morphine to IV-PCA in Patient With Unsatisfactory Analgesia Post Laparotomy
The purpose of this study is to improve IV-Patient Controlled Analgesia (IV-PCA) technique for postoperative analgesia. Investigators are comparing between patient re-education and the background morphine infusion among patients…
- Trial name
- NCT02523846
- Testing
- morphine, Patient re-education
- Where
- Malaysia
- Volunteers
- 160 people
- Sponsor
- Clinical Research Centre, Malaysia
Postoperative Pain Management, Lumbar Spinal Fusion Surgery
Single- Versus Two-Level ESP Block for Analgesia After Lumbar Stabilization Surgery
Lumbar stabilization surgery is commonly associated with moderate to severe postoperative pain. Effective pain control is important to improve patient comfort, early mobilization, and recovery.
- Conditions
- Postoperative Pain Management, Lumbar Spinal Fusion Surgery, Erector Spina Plan Block
- Trial name
- ESP-Lumbar (NCT07363096)
- Testing
- Single-Level Erector Spinae Plane Block, Two-Level Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Pain, Postoperative, Mammaplasty
Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Patient Undergoing Breast Reconstruction With Tissue Expander
Patients undergoing breast reconstruction with tissue expanders will be treated with a local anesthetic during their procedure and monitor their post-operative pain level and amount of oral pain medication taken.
- Trial name
- NCT04278846
- Testing
- Depofoam bupivacaine, Bupivacaine hydrochloride (HCl)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Acute Pain, Surgery
Auriculotherapy for Surgical Pain
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Conditions
- Acute Pain, Surgery, Shoulder Pain
- Trial name
- NCT03860259
- Testing
- Auriculotherapy cryopuncture device without nitrogen gas, Auriculotherapy cryopuncture device with nitrogen gas
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jacques E. Chelly
Postoperative Pain
Peritoneal Nebulization of Ropivacaine for Pain Control After Laparoscopic Colectomy
The purpose of this study is to assess if intraperitoneal nebulization of Ropivacaine 150 mg produces better postoperative pain control than Saline nebulization after laparoscopic colectomy.
- Trial name
- NCT01432496
- Testing
- Ropivacaine 150 mg, saline 15 ml
- Where
- 3 sites in Italy
- Volunteers
- 130 people
- Sponsor
- San Gerardo Hospital
Postoperative Pain, Lumbar Surgery
Retrolaminar Analgesia for LuMbar Surgery
This randomized controlled trial evaluates the effectiveness of ultrasound-guided retrolaminar nerve block in addition to standard multimodal analgesia for postoperative pain management in patients undergoing lumbar spine…
- Conditions
- Postoperative Pain, Lumbar Surgery, Back Pain Lower Back Chronic, Opioid Analgesia
- Trial name
- REALM (NCT07334288)
- Testing
- Ultrasound-Guided Retrolaminar Block, Standard Analgesia
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Universidad de los Andes, Chile
Postoperative Acute Pain, Breast Cancer
IPP-PSP Block vs. SPSIPB in Breast Surgery
This prospective, randomized clinical study aims to compare the analgesic efficacy of the interpectoral-pectoserratus plane block and the serratus posterior superior intercostal plane block for postoperative pain management in…
- Conditions
- Postoperative Acute Pain, Breast Cancer, Regional Anesthesia
- Trial name
- NCT07246720
- Testing
- Interpectoral-Pectoserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Zonguldak Bulent Ecevit University
Postoperative Pain
Evaluation of Preoperative Use of Pregabalin on Postoperative Analgesia After Laparoscopic Colorectal Surgery
The purpose of this study is to evaluate how effective is the preoperative administration of pregabalin 300mg, to attenuate postoperative pain and opioids consumption after laparoscopic colorectal surgery
- Trial name
- NCT01940224
- Testing
- Pregabalin, Morphine
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Larissa University Hospital
Cannabis Use, Opioid Consumption
A Comparison of Post-Operative Analgesia Requirements In Recreational Cannabis Users Versus Cannabis Naïve Inflammatory Bowel Disease Patients
Cannabis is a drug that is widely used for recreational purpose. In most patients undergoing surgery, opioids are the most widely used mode of pain relief, during and following surgery.
- Trial name
- NCT04055662
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Mount Sinai Hospital, Canada
Femoral Fractures, Postoperative Pain
Comparison of Two Different Approaches in the Fascia Iliaca Compartment Block in Femoral Fracture Surgery
Fascia Iliaca Compartment Block (FICB) is a popular regional anaesthetic technique for surgical procedures involving the hip joint and femur.
- Trial name
- NCT05172869
- Testing
- Suprainguinal Performed FICB, Infrainguinal Performed FICB
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara City Hospital Bilkent
Arthroplasty, Replacement, Knee, Pain, Postoperative
Adductor Canal Block for Total Knee Arthroplasty
Total knee arthroplasty (TKA) can be associated with a large amount of postoperative pain. This pain can oftentimes be severe enough to limit participation in physical therapy and ultimately delay discharge resulting in increased…
- Trial name
- NCT02453360
- Testing
- Adductor Canal Block
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Wisconsin, Madison
Pain, Cesarean Section
Intrathecal Hydromorphone for Pain Control After Cesarean Section
The use of intrathecal opioids for analgesia in the setting of cesarean section has become standard obstetric anesthesia practice. Currently, two opioids are commonly used. These opioids are fentanyl and morphine (Duramorph).
- Trial name
- NCT02096003
- Testing
- Intrathecal morphine, Intrathecal hydromorphone
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Percutaneous Nephrolithotomy
Lower Thoracic Epidural vs Erector Spinae Block for PNL
compare the efficacy of Lower Thoracic Epidural with Erector spinae plane block (ESPB) for post-operative analgesia after Percutaneous Nephrolithotomy with a hypothesis that both Lower Thoracic Epidural and Erector spinae plane…
- Trial name
- NCT05725083
- Testing
- Lower thoracic epidural, Erector spinae plane block
- Volunteers
- 42 people
- Sponsor
- Assiut University
Supratentorial Neoplasms
Pre- vs. Postoperative Scalp Block for Pain Control After Supratentorial Craniotomy
Study was designed to evaluate optimal timing for selective scalp block in patients undergoing general anesthesia for supratentorial craniotomy.Pain score assessed by visual analog scale (VAS) preoperatively (baseline) and after…
- Trial name
- NCT04344132
- Testing
- Scalp Block
- Volunteers
- 50 people
- Sponsor
- University of Roma La Sapienza
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