Clinical trials: Analgesia, Postoperative
Pain, Postoperative
A Comparison of the Safety and Effectiveness of Two Forms of Patient-controlled Pain Medication Used After Scheduled Abdominal or Pelvic Surgery: The Fentanyl Transdermal System Versus the Morphine Intravenous Pump
The purpose of this study is to compare two pain medications delivered by two different forms of patient-controlled pain management systems: the Fentanyl HCl Patient-Controlled Transdermal System (E-TRANS fentanyl) and the…
- Trial name
- NCT00266539
- Testing
- E-TRANS Fentanyl hydrochloride; Morphine
- Volunteers
- 506 people
- Sponsor
- Alza Corporation, DE, USA
Laparoscopic Cholecystectomy Surgery Postoperative Analgesia
RLB vs ERSP for Postoperative Analgesia in Lap Cholecystectomy
This prospective, randomized, double-blind clinical trial evaluates the comparative effectiveness of ultrasound-guided retrolaminar block (RLB) and erector spinae plane block (ESPB) for postoperative analgesia in patients…
- Trial name
- NCT07598162
- Testing
- Retrolaminar Block (RLB), Erector spinae plane block (ESPB)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Pain Score Reduction, Effectiveness of Acetaminophen
Effectiveness Of Intravenous Vs Rectal Acetaminophen For Pain Management In Post Operative Neonates
This randomized controlled trial aims to evaluate the effectiveness of intravenous (IV) versus rectal acetaminophen for postoperative pain management in neonates.
- Conditions
- Pain Score Reduction, Effectiveness of Acetaminophen, Postoperative Pain Management in Neonates, Rescue Analgesia
- Trial name
- NCT06638086
- Testing
- Acetaminophen Suppositories, Acetaminophen Injection
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Rawalpindi Medical College
Anterior Ilıac Block, Hernia Surgery
Effect of Anterior Iliac Block on Postoperative Analgesia and Patient Satisfaction in Inguinal Hernia Repair Surgery
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide and presents challenges in anesthesia selection and postoperative pain management.
- Conditions
- Anterior Ilıac Block, Hernia Surgery, Spinal Anesthesia
- Trial name
- NCT07533383
- Testing
- Anterior Iliac Block, Control Group (A):
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Anesthesia, Anesthesia Recovery Period
Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy.
Postoperative quality of recovery (QoR) could be related to anesthesia and postoperative analgesia. This study is exploring early QoR after radical prostatectomy in the two groups of anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Radical Prostatectomy, Patient Satisfaction
- Trial name
- QoR (NCT04587505)
- Testing
- Epidural anesthesia with light general anesthesia, Postoperative epidural analgesia, General anesthesia
- Where
- Croatia
- Volunteers
- 61 people
- Sponsor
- University Hospital of Split
Colon Cancer, Colon Diverticulosis
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery…
- Conditions
- Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis
- Trial name
- NCT02958566
- Testing
- Acetaminophen, Gabapentin, Orphenadrine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Illinois College of Medicine at Peoria
Bariatric Surgery Candidate, Pain, Postoperative
Efficacy of External Oblique Intercostal Block in Laparoscopic Bariatric Surgery
Laparoscopic bariatric procedures nowadays are employed under ERAS protocol as an ambulatory surgery. Pain after laparoscopic procedures arises significantly from port site incisions in the anterior abdominal wall, and shoulder…
- Conditions
- Bariatric Surgery Candidate, Pain, Postoperative, Narcotic Use, Analgesia
- Trial name
- NCT05592522
- Testing
- External oblique intercostal block, Oblique subcostal TAP block, Posterior Rectus sheath block
- Where
- Saudi Arabia
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Al Mashfa Medical Center
Postoperative Analgesia, Medial Unicompartmental Knee Arthroplasty
Adductor Canal Block for Medial Compartment Knee Arthroplasty
This study will evaluate the affects of a single injection ultrasound-guided adductor canal block for patients undergoing robotic-assisted (MAKOplasty) medial UKA (unicompartmental knee arthroplasty).
- Trial name
- NCT01818531
- Testing
- Adductor canal block, Lumbar plexus block
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Wake Forest University Health Sciences
Abdominal Surgery, Postoperative Pain
External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery
Postoperative pain after laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery) is often severe, and inadequate analgesia may lead to increased opioid use, opioid dependence, and poor…
- Trial name
- NCT07331441
- Testing
- External Oblique Intercostal Plane Block, Standard multimodal analgesia
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Jun Zhang
Pain, Postoperative
Preemptive Analgesia for Postoperative Pain Control for Dental Treatment Under General Anesthesia
The aim of this study was to compare the analgesic-treated children with analgesic prior to the treatment and to compare the postoperative analgesic needs of children undergoing dental treatment under general anesthesia.
- Trial name
- NCT03852602
- Testing
- Preemptive Analgesics, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Aydin Adnan Menderes University
Postoperative Pain, Delirium - Postoperative
Analgesia Methods and Early Mobilization in Geriatric ICU Patients After Major Surgery
This study looks at how different pain-control methods affect how quickly older adults get out of bed and start moving again after major surgery.
- Conditions
- Postoperative Pain, Delirium - Postoperative, Frailty, Postoperative Care in Geriatric Intensive Care Patients
- Trial name
- NCT07709975
- Testing
- Systemic Opioid Analgesia (± Multimodal), Epidural Analgesia, Peripheral Nerve Block (± Multimodal)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Femoral Neck Fractures
Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip Screw
Falls are a common problem in elderly patients resulting fractured femur, which require early operation. Adequate postoperative pain control will provide good recovery.
- Trial name
- NCT01219088
- Testing
- Bupivacaine, morphine
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Pain, Pain, Postoperative
Intervention Study to Enhance Patients' Pain Management After Cardiac Surgery
The main objective of this randomized controlled trial is to evaluate the effect of an intervention formed as a pain booklet provided to patients at discharge from hospital following cardiac surgery.
- Conditions
- Pain, Pain, Postoperative, Other Functional Disturbances Following Cardiac Surgery
- Trial name
- NCT01976403
- Testing
- Pain Booklet
- Where
- Norway
- Volunteers
- 416 people
- Sponsor
- Oslo Metropolitan University
Osteoarthritis, Hip, Hip Osteoarthritis
Intravenous Dexamethasone (0 vs 4 vs 8 mg) as an Adjunct to PENG Block for Postoperative Analgesia in Total Hip Arthroplasty: A Randomized Double-Blind Trial
his study will test whether giving dexamethasone through a vein can improve pain control after total hip replacement surgery. Dexamethasone is commonly used to reduce nausea and may also help with pain, but it is not clear which…
- Trial name
- NCT07581470
- Testing
- Dexamethasone 4mg, Dexamethasone 8mg
- Where
- Poland
- Volunteers
- 198 people
- Sponsor
- Poznan University of Medical Sciences
Gastric Cancer
Comparison of the Effects of Continuous Epidural Analgesia and Continuous Intravenous Analgesia on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy
The investigators hypothesized that sympatholytic effect of epidural analgesia would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery.
- Trial name
- NCT02458573
- Testing
- continuous epidural analgesia, continuous intravenous analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Yonsei University
Postoperative Cognitive Dysfunction, Orthopedic Procedures
Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery
This study aims to compare two medications, Remimazolam and Midazolam, used for sedation during orthopedic surgeries performed under regional anesthesia.
- Conditions
- Postoperative Cognitive Dysfunction, Orthopedic Procedures, Postoperative Pain Management, Hip Fracture
- Trial name
- REMIND-ORTHO (NCT07113483)
- Testing
- Midazolam, REMIMAZOLAM BESYLATE 2.5 Mg in 1 mL INTRAVENOUS INJECTION, POWDER, LYOPHILIZED, for SOLUTION [BYFAVO]
- Where
- Romania
- Volunteers
- 120 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition
Postoperative Pain, Cesarean Delivery
Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial
The goal of this clinical trial is to compare intrathecal bupivacaine with or without morphine for postoperative analgesia in patients undergoing elective cesarean section.
- Conditions
- Postoperative Pain, Cesarean Delivery, Analgesia, Obstetrical
- Trial name
- NCT07094802
- Testing
- Intrathecal morphine with bupivacaine, Hyperbaric Bupivicaine
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Postoperative Pain; Knee Arthroscopy; Acupuncture
Acupuncture for Pain Control After Ambulatory Knee Arthroscopy
Aim of the study: To investigate whether acupuncture with indwelling fixed needles reduces pain and analgesic requirement and foster mobilization in patients after arthroscopic knee surgery (AKS) Design: Prospective pilot…
- Trial name
- AcuK-Scope (NCT04134702)
- Testing
- Acupuncture
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Post Operative Analgesia
Erector Spinae Catheter for Open Heart Surgery
Fast track to Extubation after cardiothoracic surgery is becoming more common after a number of reports showing it is safe and effective. However, It has introduced new challenges to pain control.
- Trial name
- ESPADULT2 (NCT03901612)
- Testing
- Ropivacaine 0.2%, saline 09%
- Where
- Vietnam
- Sponsor
- Vinmec Healthcare System
Nerve Block, Pain, Postoperative
Fascia Iliaca Compartment Block Versus Quadratus Lumborum Block in Total Hip Arthroplasty
Patients undergoing total hip arthroplasty are randomly assigned to two groups (fascia iliaca compartement block [FICB] group or quadratus lumborum block [QLB] group).
- Trial name
- NCT05228028
- Testing
- fascia iliaca compartement block, quadratus lumborum block
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
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