Clinical trials: Analgesia, Postoperative
Adolescent Idiopathic Scoliosis
Single vs Double Epidural Catheter Analgesia for Scoliosis Surgery
This is a study comparing pain control utlilizing one or two epidural catheters, along with a hydromorphone PCA, for analgesia following surgery for correction of scoliosis.
- Trial name
- NCT01900626
- Testing
- epidural catheter
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Wisconsin, Madison
Post Operative Analgesia
Epidural Versus Quadratus Lamborum Block in Adult Open Nephrectomies
Our primary objective is to compare the effectiveness of bilateral QLB and epidural analgesia for postoperative management using VAS measured in PACU until 24 hours after surgery in patients undergoing elective open nephrectomies…
- Trial name
- NCT05174364
- Volunteers
- 62 people
- Sponsor
- Assiut University
Post Operative Pain
Comparing Between Ultrasound Guided Pectoral Nerve Block Versus Ultrasound Guided Mid-point Transverse Process Block for Postoperative Analgesia in Patients Undergoing Modified Radical Mastectomy
The aim of the study is to compare the effectiveness of ultrasound guided pectoral nerve block versus mid-point transverse process block for postoperative analgesia in patients undergoing modified radical mastectomy
- Trial name
- NCT06873893
- Testing
- Midpoint transverse process block, Pectoral Nerve Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Thyroid Diseases, Goiter
Thyroidectomy-specific Enhanced Recovery After Surgery (ERAS) Protocol
Thyroidectomy is generally considered a low-to-moderate risk operation; however, postoperative pain, nausea/vomiting, and prolonged hospital stays remain common issues.
- Conditions
- Thyroid Diseases, Goiter, Thyroid Neoplasms
- Trial name
- NCT07575243
- Testing
- Enhanced Recovery After Surgery protocol, Conventional perioperative care
- Where
- Egypt
- Volunteers
- 143 people
- Sponsor
- Assiut University
Breast Cancer, Postoperative Pain
Comparison of Pre-op and Post-op Pectoralis Nerve Block
The investigators will compare whether patients will have better pain control if they were to receive (PEC I/II block) before surgery or after mastectomy.
- Conditions
- Breast Cancer, Postoperative Pain, Anesthesia, Nerve Block
- Trial name
- NCT03653988
- Testing
- PEC I/II blocks by anesthesiologist - pre-operative, PEC I/II blocks by surgeon - intra-operative
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Melinda Seering
Pain, Hypospadias
Dexmedetomidine Infusion and Surgical Pleth Index In Pediatrics
This non-invasive dimensionless score index -SPI-reflects the Patients' sympathetic response to surgical stimulation. Its effectiveness in detecting the balance between nociceptor activation and analgesia was not only reported…
- Trial name
- NCT05727969
- Testing
- Dexmedetomidine, Lactated Ringer, Hypospadias
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Proximal Humerus Surgery, Rotator Cuff Surgery
Effect of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Superior Trunk Block of the Interscalene Brachial Plexus on Postoperative Diaphragmatic Function and Analgesia
To compare the effects of 1.33% liposomal bupivacaine versus 0.375% bupivacaine hydrochloride for superior trunk block of the interscalene brachial plexus on postoperative diaphragmatic function and analgesic efficacy in shoulder…
- Conditions
- Proximal Humerus Surgery, Rotator Cuff Surgery, Shoulder Arthroplasty, Shoulder Arthroscopy
- Trial name
- NCT07587203
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- 3 sites in China
- Volunteers
- 184 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Postoperative Pain
Comparison of Pain Relief Post Knee Arthroscopy Using IPACK + Adductor Canal Block Vs. Adductor Canal Block Alone
In this study, the invistigators aim to compare postoperative analgesia effectiveness between combined interspace between the popliteal artery and posterior capsule of the knee block (IPACK) and Adductor canal block vs.
- Trial name
- NCT06265441
- Testing
- Group A will receive adductor canal block after spinal anesthesia under a high-frequency ultrasound guidance in which the adductor canal is identified and 20 ml of 0.25% bupivacaine will be injected, Group B will receive adductor canal block under ultrasound guide 20 ml bupivacaine 0.25% and IPACK block under direct visualization of ultrasound of 20 ml bupivacaine 0.25%
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Spine Fusion, Locoregional Anaesthesia
PeriOPerative Spine Surgery COntrol Pain (POPSSCOP) Study: Intrathecal Morphine vs Erector Spinae Plane Block for Postoperative Pain Management in Spinal Fusion
This is a prospective observational study conducted at the trauma center of Città della Salute e della Scienza of Turin. The aim of the study is to compare two local regional anesthesia techniques in multimodal analgesia for…
- Conditions
- Spine Fusion, Locoregional Anaesthesia, Intrathecal Anesthesia, Erector Spina Plan Block
- Trial name
- POPSSCOP (NCT07245524)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Postoperative Pain
FICB for Hip Fracture Pain in Elderly
Hip fracture is a common injury in elderly patients, often requiring surgical treatment. However, these patients frequently experience severe postoperative pain, which can delay mobility and recovery, and increase the risk of…
- Conditions
- Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Postoperative Pain, QoR-15, Fascia Iliaca Block
- Trial name
- FICB-PREP (NCT07762846)
- Testing
- Ultrasound-Guided Fascia Iliaca Compartment Block
- Where
- China
- Volunteers
- 144 people
- Sponsor
- RenJi Hospital
Lung Diseases
Serratus Posterior Superior Interfascial Plane Block for Thoracoscopic Surgery
Regional techniques can be used for postoperative pain control following VATS. Ultrasound (US) guided serratus posterior superior block (SPSPB) is a new interfacial plane block defined by Tulgar et al in 2023.
- Trial name
- NCT05972122
- Testing
- Analgesia management; group S and C
- Where
- Turkey (Türkiye)
- Sponsor
- Medipol University
Postoperative Pain
Low Dose Ketamine Infusion for Postoperative Analgesia After Total Knee Arthroplasty
This study evaluates continous infusion of low-dose ketamine during intraoperative and postoperative periods at three different doses to provide postoperative analgesia in total knee arthroplasty cases.
- Trial name
- NCT04085588
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Mustafa Kemal University
Scoliosis
Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery
The purpose of this study is to evaluate the effects of continuous local anesthetic delivery on the immediate post-op recovery of patients undergoing spinal fusion surgery for congenital or idiopathic scoliosis.
- Trial name
- NCT00508066
- Testing
- Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shriners Hospitals for Children
Dexamethasone, Magnesium Sulphate
Dexamethasone Versus Magnesium Sulphate as an Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block for Postoperative Analgesia in Elective Caesarean Section Under Spinal Anesthesia
This study aims to compare the efficacy of adding dexamethasone and magnesium sulfate as an adjuvant to bupivacaine in bilateral erector spinae block in postoperative pain control in patients undergoing caesarean section under…
- Conditions
- Dexamethasone, Magnesium Sulphate, Adjuvant, Ultrasound
- Trial name
- NCT07139522
- Testing
- Bupivacaine, Dexamethasone, Magnesium sulphate
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Postoperative Pain
Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery
Erector spinae plane block (ESPB) is a novel regional block technique that was proven to have superior outcomes in relieving postoperative pain in colorectal surgeries.Ketamine enhances the impact of local anaesthetics by…
- Trial name
- NCT06007378
- Testing
- Bupivacaine and ketamine, Bupivacaine and transdermal fentanyl patch, Bupivacain
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Postoperative Pain, Thoracic Surgery
Ultrasound-Guided Rhomboid-Intercostal Block Versus Thoracic Paravertebral Block for VATS Analgesia
Purpose of the study The goal of this research is to see which of two nerve-numbing techniques-the Rhomboid-Intercostal Block (RIB) or the Thoracic Paravertebral Block (PVB)-works better to control pain after chest surgery…
- Conditions
- Postoperative Pain, Thoracic Surgery, Thoracic Surgery, Video Assisted, Ultrasound Guided
- Trial name
- NCT07465887
- Testing
- Ultrasound-Guided Rhomboid-Intercostal Block (RIB), Ultrasound-Guided Thoracic Paravertebral Block (PVB)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Georgios Kotsovolis
Pain, Pain Syndrome
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06071949
- Testing
- Adezunap
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Pain, Postoperative, Developmental Dysplasia of the Hip
Postoperative Analgesic Effect of Two Peripheral Nerve Blocks for Hip Surgery in Pediatrics
Hip joint surgery for developmental dysplasia of the hip (DDH) in children is extremely painful and associated with considerable postoperative pain despite the use of systemic opioids.
- Conditions
- Pain, Postoperative, Developmental Dysplasia of the Hip, Regional Anesthesia Morbidity
- Trial name
- NCT05348421
- Testing
- FTPB, PENG Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Post Operative Analgesia
Bilateral External Oblique Intercostal Plane Bock (EOIPB) in Upper Abdominal Surgeries
The current study is designed to investigate the analgesic potentials of two modalities of abdominal blocks where local anesthetics is injected in the fascial planes of the abdominal muscles to anesthetize the nerves supplying…
- Trial name
- NCT07055438
- Testing
- Ultrasound guided Rectus sheath block, ultrasound guided external oblique intercostal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Pain, Post-operative
Serratus Anterior Plane Block in Patients Undergoing Mastectomy
This is a randomized, interventional prospective study. Patients (n=66) undergoing mastectomies with or without tissue expander will be randomized to receive a supra-serratus or sub-serratus regional plane block prior to surgery.
- Trial name
- NCT03154658
- Testing
- Ropivacaine 0.35%
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Texas Southwestern Medical Center
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