Clinical trials: Analgesic
Osteoarthritis of the Knee, Chronic Lower Back Pain
A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee
The purpose of the study is to evaluate the analgesic efficacy of ASP7962 relative to placebo. This study will also evaluate the efficacy of ASP7962 relative to placebo on pain on walking, function and stiffness; the time course…
- Trial name
- OAK (NCT02611466)
- Testing
- ASP7962, Naproxen
- Where
- 34 sites in Belgium, Czechia and 4 more
- Volunteers
- 215 people
- Sponsor
- Astellas Pharma Europe B.V.
Analgesia Disorder, Pain
A Study of Intramuscular Sebacoyl Dinalbuphine Ester for Post-Hemorrhoidectomy Pain Management
This is a randomized, double blind, placebo-controlled, single dose study to assess the safety and efficacy of intramuscular sebacoyl dinalbuphine ester (SDE) for post-hemorrhoidectomy pain management.
- Trial name
- NCT02468128
- Testing
- Sebacoyl Dinalbuphine Ester
- Where
- 6 sites in Taiwan
- Volunteers
- 221 people
- Sponsor
- Lumosa Therapeutics Co., Ltd.
Astrocytoma, Grade IV, Giant Cell Glioblastoma
Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM
This study will find the maximum safe dose (MSD) or maximum tolerated dose (MTD) of CYNK-001 which are NK cells derived from human placental CD34+ cells and culture-expanded.
- Conditions
- Astrocytoma, Grade IV, Giant Cell Glioblastoma, Glioblastoma Multiforme, Cyclophosphamide
- Trial name
- CYNK001GBM01 (NCT04489420)
- Testing
- CYNK001-IV, CYNK001-IT
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Celularity Incorporated
Chronic Pain
Validating and Evaluating the Pain Medicine Digital Workflow Algorithm (PGS 1.0)
This is a prospective, non-randomized, double blind, single center, single arm, validation study, to evaluate the performance of PGS 1.0 algorithm in analyzing pain specific symptoms and medical history data of pain patients…
- Trial name
- NCT07195162
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- PG Medical Systems Ltd.
Healthy
Bioequivalence Trial of a New Opioid Combination Compared to Reference
The purpose of this study is to demonstrate bioequivalence of a new formulation to a reference
- Trial name
- NCT00460785
- Testing
- Opioid
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH