Clinical trials: Analgesic
Heel Spur
A Comparison of the Analgesic Efficacies of Ultrasound and Shock Wave Therapy in the Patients With Calcaneal Spur
Heel spur is a troublesome disorder. Its formation is accompanied by pain in the area of heel and it makes walking limited or even impossible.
- Trial name
- NCT01510249
- Volunteers
- 3 people
- Sponsor
- Medical University of Lodz
Analgesics, Opioid, Anesthetics, Local
Opioid Use of Local Anaesthetic Agents in Open Heart Surgery and Its Effect on Recovery
The aim of this randomized controlled study was to investigate the effect of injecting local anesthetic agents into the sternotomy incision site and around the drains on the amount of opioids used in the postoperative period and…
- Trial name
- NCT06642077
- Testing
- LIDOFAST 40 mg/2 ml + 0.025 mg/2 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Undesired Pregnancy
Comparing the Effectiveness of Oral Versus Intravenous Pain Medicine for Suction Curettage (D&C)
The main objective of this study is to determine the equivalency of oral conscious sedation and intravenous conscious sedation for first trimester surgical abortion.
- Trial name
- NCT00337792
- Testing
- oxycodone + lorazepam versus fentanyl + midazolam
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Congenital Muscular Torticollis
Ultrasound Guided Intermediate Cervical Plexus Block for Congenital Muscular Torticollis
Congenital Muscular Torticollis (CMT) is a postural deformity of head and neck detected at birth or shortly after birth, primarily resulting from unilateral shortening of Sternocleidomastoid Muscle (SCM).
- Trial name
- NCT02651311
- Testing
- intermediate cervical plexus block, Fentanyl, Ibuprofen
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Ajou University School of Medicine
Dental Pain
Maxi-Analgesic Phase 2 Study to Compare the Analgesic Effects in Different Dosing Groups to Treat Teeth Extraction Pain
The aim of the study is to examine the dose response relationship in the treatment of dental pain (teeth extraction) for the different potential doses of the investigational drug, i.e.
- Trial name
- NCT01104844
- Testing
- Full Dose Strength, Quarter dose strength, Half dose strength
- Where
- United States
- Sponsor
- AFT Pharmaceuticals, Ltd.
Acute Pain
IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients
The goal of this randomized clinical trial is to compare the analgesic efficacy and side effect profile of IV acetaminophen as an analgesic adjunctive medication to IV hydromorphone for the treatment of acute pain experienced by…
- Trial name
- NCT03553498
- Testing
- IV acetaminophen, hydromorphone
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Albert Einstein College of Medicine
Anesthesia
Remifentanil on Hemodynamic Response to Anesthesia Induction
Effects of different doses of remifentanil on hemodynamic response to anesthesia induction in elderly patients ABSTRACT OBJECTİVE: The investigators compared the effects of three different doses of remifentanil infusion, which…
- Trial name
- NCT02763098
- Testing
- Remi 0.1, Remi 0.2, Remi 0.3
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
Nerve Block, Video-Assisted Thoracic Surgery
Long Thoracic Nerve Blockade for Pain Treatment After Video-Assisted Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) provides an opportunity to penetrate the thoracic cavity by video through an incision into the chest wall and facilitate surgical operation of lung pathologies.Various regional methods…
- Trial name
- NCT03483415
- Testing
- Morphine Sulfate, Bupivacaine
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Cardiac Surgery, Postoperative Pain
Erector Spinae Plane (ESP) Block With 20 ml Versus 30 ml in Cardiac Surgery
Even though erector spinae plane (ESP) block is shown to be efficient in cardiac surgery, it is still controversial how much volume is necessary for efficient analgesic effect for sternotomy and drain tube pain relief.
- Trial name
- NCT04928521
- Testing
- bilateral erector spinae plane block with 30 mL 0.25 % bupivacaine, bilateral erector spinae plane block with 20 mL 0.25 % bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara City Hospital Bilkent
Medication Adherence
Study to Test the Efficacy of Online Education to Increase Safe Use of Opioid Medication.
The purpose of this project is to test whether an online pain medication intervention is a feasible and effective way to increase opioid pain medication safety.
- Trial name
- NCT01770314
- Testing
- Experimental
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Inflexxion, Inc.
Onset and Duration of Sensory and Motor Block of Femoral Nerve,, Visual Analogue Pain Scores,
Perineural Dexmedetomidine and Femoral Nerve Block
The duration of sensory block after single dose of long acting local anesthetics is not sufficient to avoid the postoperative use of opioids.
- Conditions
- Onset and Duration of Sensory and Motor Block of Femoral Nerve,, Visual Analogue Pain Scores,, Time to First Request of Rescue Analgesics,, Total Morphine Consumption in 24 Hours
- Trial name
- NCT01964040
- Testing
- peri-neural dexmedetomidine as adjuvant to bupivacaine in femoral nerve block
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Herpes Zoster, Neuralgia
An Open-Label Extension Study of NGX-4010 for the Treatment of Neuropathic Pain
This study is an open-label, multicenter, extension study for subjects who completed NeurogesX Study C111 and received treatment with NGX-4010 (Capsaicin Patch) within 12 weeks (up to +7days) before entry into Study C114
- Conditions
- Herpes Zoster, Neuralgia, Pain, HIV Infections
- Trial name
- NCT00089557
- Testing
- Capsaicin Dermal Patch
- Sponsor
- NeurogesX
Intervertebral Disc Degeneration
Duloxetine as an Analgesic Agent in Patients Undergoing Elective Spine Surgery
Duloxetine as an analgesic agent in patients undergoing elective spine surgery: evaluation with fentanyl demand controlled by the patient.
- Trial name
- Duloxetine (NCT02535000)
- Testing
- Duloxetine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Serviço de Anestesiologia de Joinville
Abortion, Induced
Postoperative Pain After Medical Abortion Under Local Anesthesia : Comparison of Several Analgesic Regimen
To compare postoperative analgesia by paracetamol 1gr or ketoprofen 100 mg or the combination of these two analgesics each treatment beeing allocated by randomization
- Trial name
- NCT00188071
- Testing
- paracetamol, ketoprofen, ketoprofen + paracetamol
- Where
- France
- Volunteers
- 240 people
- Sponsor
- University Hospital, Angers
Acute Pain, Postoperative, Postoperative Pain
Characterization of Acute Pain
This study aims to better understand how acute pain and responses to pain treatment can be measured in children and adolescents using a non-invasive device.
- Conditions
- Acute Pain, Postoperative, Postoperative Pain, Acute Pain
- Trial name
- NCT07336264
- Testing
- AlgometRx Nociometer
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Children's National Research Institute
Analgesics, Opioid, Anesthesia, Endotracheal
Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery
Opioid-free anesthesia (OFA) is a multimodal technique that eliminates intraoperative opioids by combining dexmedetomidine, ketamine, lidocaine, NSAIDs, and regional analgesia.
- Conditions
- Analgesics, Opioid, Anesthesia, Endotracheal, Anesthesia, General
- Trial name
- NCT06380244
- Testing
- anesthesia without opioids
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- Jagiellonian University
Colectomy
Parecoxib In Post Surgery (Hemicolectomy) Pain
This is a phase III, multicenter, open label, pilot to evaluate the analgesic efficacy and safety of parecoxib 40 mg IV in the treatment of the pain following hemicolectomy in an optimal management of the surgical patient
- Trial name
- NCT00139607
- Testing
- Paracoxib
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Pfizer
Superior Hypogastric Plexus Block, Transversus Abdominis Plane Block
Combination of Superior Hypogastric Plexus Block and Transversus Abdominis Plane Block in Abdominal Hysterectomies
This study aims to evaluate the analgesic effect of superior hypogastric plexus block combined with transversus abdominis plane block in abdominal hysterectomies.
- Conditions
- Superior Hypogastric Plexus Block, Transversus Abdominis Plane Block, Abdominal Hysterectomies
- Trial name
- NCT07606781
- Testing
- Superior hypogastric plexus block + Transverse abdominis plane, Superior hypogastric plexus block
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Comparison of US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural
Comparison of US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy
The investigators hypothesize that US Bilateral Erector Spinae Plane Block, US Bilateral Quadratus Lumborum Block and Lumbar Epidural for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy resulting in…
- Trial name
- NCT06397300
- Testing
- bilateral Ultrasound guided erector spinae plane (ESP) block, quadratus lumborum block, lumbar epidural
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Hemorrhoid
Efficacy of Rectal Infiltration of Exparel for Analgesic Benefit Following Hemorrhoidectomy
The purpose of this study is to compare the quality and duration of pain relief after a hemorrhoidectomy, provided by locally administered liposomal bupivacaine versus bupivacaine hcl or control with saline.
- Trial name
- NCT02104414
- Testing
- Exparel, Bupivacaine HCl with Epinephrine, Normal Saline
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.