Clinical trials: Analgesic
Dexmedetomidine, Fascia Iliaca Block
Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery
To examine the impact of various administration routes of dexmedetomidine in conjunction with ultrasound-guided fascia iliaca block (FIB) on emergence agitation (EA) during the postoperative recovery period after hip replacement…
- Trial name
- NCT06614010
- Testing
- Dexmedetomidine Injection, Ropivacaine and Dexmedetomidine, Sodium Chloride Injection
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Qianfoshan Hospital
Total Joint Arthroplasty
The Effect of Guided Imagery Technique on Anxiety, Pain, and Analgesic Use in Total Joint Arthroplasty Patients
This randomized controlled study will investigate the effects of guided imagery on preoperative anxiety and postoperative pain and analgesic consumption in patients undergoing total joint arthroplasty.
- Trial name
- NCT07194252
- Testing
- Guided imagery technique application
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ankara Yildirim Beyazıt University
Healthy, Inflammation
Using a Narcotic to Enhance the Numbing Effect of the Local Anesthetic Lidocaine on Inflamed Molar Teeth
The effectiveness of local anesthetics is reduced if inflammation is present, making it difficult to control pain during such procedures as root canals and wisdom teeth removal.
- Conditions
- Healthy, Inflammation, Mouth Disease, Pain
- Trial name
- NCT00001952
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Pain
A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental Pain
The purpose of this study is to evaluate how well a fixed combination of acetaminophen/naproxen sodium relieves postoperative dental pain compared with acetaminophen, naproxen sodium and placebo.
- Trial name
- NCT05761574
- Testing
- Acetaminophen/Naproxen Sodium Fixed Combination, Naproxen Sodium, Acetaminophen
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Rotator Cuff Tear, Rotator Cuff Injury
Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair
Arthroscopic rotator cuff repair is associated with poor post-operative pain management. The multimodal analgesic scheme (oral non-steroidal anti-inflammatory drugs associated with oral opioids) currently used according to the…
- Conditions
- Rotator Cuff Tear, Rotator Cuff Injury, Analgesics, Opioid, Buprenorphine
- Trial name
- NCT03380533
- Testing
- Buprenorphine, Multimodal Oral Scheme, Tramadol
- Where
- Argentina
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Eventration, Regional Anesthesia
Serratus Intercostal Block Versus Epidural/Port Infiltration Analgesia in Eventration: Prospective Non Inferiority Study
Adequate pain control, rehabilitation and early postoperative recovery are currently the model to follow according to the recommended guidelines.In this project the main objective is to evaluate 2 different analgesic strategies…
- Conditions
- Eventration, Regional Anesthesia, Epidural; Anesthesia, Abdominal Hernia
- Trial name
- Analgesic Stra (NCT06014749)
- Testing
- undergo, ultrasound, Local anesthetic
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Hospital del Rio Hortega
Pain, Postoperative, Post Operative Analgesia
Low Versus Standard Volume EXORA Block in Laparoscopic Cholecystectomy
The original EXORA block used high local anesthetic volume (50 mL total), raising concerns about local anesthetic systemic toxicity (LAST).
- Trial name
- NCT07507799
- Testing
- EXORA block 15, EXORA block 25
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Fayoum University Hospital
Gynecologic Disease
Analgesic Effects of US Bilateral Rectus Sheath Block for Laparoscopic GY Surgery
Rectus sheath block (RSB) is a kind of anterior abdominal wall block. It has postoperative analgesic effect for abdominal surgery with midline incision.
- Trial name
- NCT02476799
- Testing
- Rectus sheath block, Ropivacaine, Bandage
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Anesthesia, Local
Effectiveness of Buccal Infiltration During Vital Pulpotomy After Administering Two Analgesic Premedications
This Randomized study was designed to assess and compare the effect of two analgesic premedications (Ibuprofen BP 100 mg/5 ml and Paracetamol 200 mg/5ml.) on the anesthetic efficacy of buccal infiltration in vital pulpotomy of…
- Trial name
- NCT03423329
- Testing
- Brufen, Cital
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Visual Analogue Scale
Septorhinoplasty and Pain Score Course
To provide scientific contribution to more effective and timely pain management strategies in the postoperative period by evaluating the time-dependent course of pain scores and the effect of analgesic intervention timing on…
- Trial name
- NCT07015229
- Testing
- septorhinoplasty
- Volunteers
- 78 people
- Sponsor
- Istinye University
Pain After Shoulder Surgery
Analgesic Efficacy of the Infraspinatus-Teres Minor (ITM) Interfascial Plane Block After Shoulder Arthroscopy: A Simon's Two-Stage Design
The main study objective is to observe the ability of the ITM block to provide clinically acceptable pain control after elective shoulder arthroscopy as measured by pain scores and morphine consumption.
- Trial name
- ITM (NCT07808008)
- Testing
- Infraspinatus-teres minor block
- Where
- Switzerland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Radiculopathy Lumbar, Radiculopathy, Lumbosacral Region
Radiofrequency for Chronic Radicular Lumbar Pain: Geriatric vs. Young Patients
This study aims to evaluate the treatment response and lumbar magnetic resonance imaging (MRI) findings of patients who have undergone pulsed radiofrequency therapy for chronic radicular lumbar pain at the dorsal root ganglia.
- Conditions
- Radiculopathy Lumbar, Radiculopathy, Lumbosacral Region, Chronic Pain
- Trial name
- NCT06903949
- Testing
- Lumbar Dorsal Root Ganglia Pulsed Radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ankara Etlik City Hospital
Pancreatitis, Acute
Transversus Abdominis Plane Block in the Analgesia of Acute Pancreatitis
Background Severe abdominal pain is a hallmark of acute pancreatitis (AP). A control pain is often difficult. Transversus Abdominis Plane (TAP) block has been used in pain control in patients with exacerbation of chronic…
- Trial name
- TAPA (NCT04037449)
- Testing
- TAP block, Conventional analgesia
- Volunteers
- 44 people
- Sponsor
- Consorci Sanitari Integral
Osteoarthritis of the Knee
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee
To compare the analgesic efficacy and safety of ABT-652 administered twice daily (BID) to placebo in subjects with osteoarthritis (OA) of the knee.
- Trial name
- NCT01207115
- Testing
- ABT-652, Naproxen
- Where
- 38 sites in United States, Australia and 3 more
- Volunteers
- 322 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Postoperative Analgesia, Hip Surgery
PENG vs Deep Iliacus Plane Block in Intertrochanteric Femur Fractures
Intertrochanteric femur fractures are common in elderly patients and are associated with significant pain. Providing effective analgesia is clinically important both during positioning for spinal anesthesia and in the…
- Trial name
- NCT07513740
- Testing
- Intravenous Analgesia, Pericapsular nerve group (PENG) block, Deep Iliacus Plane Block (DIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Pain
Study to Collect Information on How Well the Study Drug Naproxen Sodium Tablets Works Compared to Hydrocodone/Acetaminophen Tablets in Order to Relieve Pain in Participants Experiencing Moderate to Severe Pain After Having Their Wisdom Teeth Removed
With this study researchers want to collect information on how long the pain relief lasts after a fixed dose of naproxen sodium or hydrocodone/acetaminophen or placebo (contains no medication) over 12 hours in subjects…
- Trial name
- NCT04307940
- Testing
- Naproxen Sodium (Aleve, BAY117031), Hydrocodone/Acetaminophen
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Bayer
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Post Operative Pain
Analgesic Effect of M-TAPA and TAPB on Laparoscopic Cholesistectomy
Cholecystectomy is the most frequently performed abdominal surgery in developed nations, with laparoscopic cholecystectomy being recognized as the gold standard technique for treating gallstones.
- Trial name
- NCT06662617
- Testing
- modified thoracoabdominal nerve block through perichondrial approach, Transversus Abdominal Plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Renal Transplantation, Nerve Block
Comparison Between Ultrasound Guided Quadratus Lumborum Block and Erector Spinae Plane Block as an Analgesic Modality in Renal Transplant Donors
Open surgery remains one of the approaches used for those patients requiring partial or radical nephrectomy and is associated with a high incidence of intense immediate postoperative pain (Gupta et al., 2013; Bravi et al., 2019).
- Trial name
- NCT07749040
- Testing
- Renal transplantation
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Postoperative, Bunion
Safety and Efficacy Study of COV155 for Post-operative Bunionectomy Pain
The purpose of this study is to show the effectiveness of COV155 compared to placebo in subjects with acute moderate to severe pain following bunionectomy surgery.
- Trial name
- NCT01743625
- Testing
- COV155
- Where
- 5 sites in United States
- Volunteers
- 406 people
- Sponsor
- Mallinckrodt
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