Clinical trials: Analgesic
Breast Neoplasm Female, Analgesics
U/S Guided Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block vs Type 2 Pectoral Nerve Block
The aim of this study is to compare between U/S Guided Rhomboid Intercostal Block Combined with Sub-Serratus Plane Block vs type 2 Pectoral Nerve Block in Analgesia for Breast Cancer Surgery by measuring intraoperative…
- Trial name
- NCT06274814
- Testing
- U/S guided Type 2 Pectoral Nerve Block, U/S guided RIB combined with the sub-serratus plane block (RISS)
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- National Cancer Institute, Egypt
Surgery
Analgesic Efficacy of Intravenous Dexmedetomidine for Supraclavicular Plexus Block
The goal of the study is to compare the duration of analgesia in patients undergoing forearm or hand surgery with a supraclavicular brachial plexus block, who receive either iv dexmedetomidine or placebo.
- Trial name
- TwoDex (NCT05389852)
- Testing
- Dexmedetomidine
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Hôpital du Valais
Induced Abortion, Medical Abortion
Assessment of Pain During an Abortion With Knowledge of the Predictive Factors of Pain.
Two studies carried out in 2011 at the Center for Contraception and Voluntary Interruption of Pregnancy (CIVG) at the Louis-Mourier Hospital, evaluated the pain of patients undergoing an abortion, and looked for predictors of the…
- Conditions
- Induced Abortion, Medical Abortion, Surgical Abortion, Pain
- Trial name
- NCT05532085
- Testing
- Evaluation of pain during voluntary termination of pregnancy with medication following consideration of predictive factors of pain without an established analgesic protocol, Evaluation of pain during a voluntary medical termination of pregnancy following consideration of predictive factors of pain with an established analgesic protocol, Assessment of pain during voluntary termination of pregnancy by aspiration under local anesthesia following consideration of predictive factors of pain without an established analgesic protocol
- Where
- France
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Olivier CHASSANY
Myotoxicity
CPK Levels After LC and Association With Analgesic Modalities
Regional anesthesia and analgesia technics are widely and securely used during general surgery procedures. Interfascial plane blocks are the latest used ones for analgesia.
- Trial name
- NCT06508177
- Testing
- İnterfascial plane block, Standart analgesia plan
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun University
Postoperative Pain
Efficacy of Erector Spinae Plane Block in Caridac Surgery
Introduction: Opioid-based pharmacological treatment is frequently used in the treatment of pain after coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT05312957
- Testing
- erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Postoperative Pain
Phase 2 Herniorrhaphy Study for Opioid Elimination
This is a Phase 2, open-label study in subjects undergoing unilateral open inguinal herniorrhaphy.
- Trial name
- NCT03695367
- Testing
- HTX-011, Luer lock applicator, Vial access device
- Where
- 5 sites in United States
- Volunteers
- 63 people
- Sponsor
- Heron Therapeutics
Post Operative Pain, Caesarean Section
Naldebain® Extended-release Injection After Cesarean Section in Pain Management
Cesarean section is one of the surgeries most commonly leading to postoperative severe acute pain. It was reported that the mean worst pain intensity reached to 6.14 one day after cesarean section in Germany.
- Conditions
- Post Operative Pain, Caesarean Section, Analgesia
- Trial name
- NCT05446311
- Testing
- Dinalbuphine sebacate
- Volunteers
- 20 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Cervical Spine Surgery
Analgesic Efficacy of the Novel Intra- Semispinal Fascial Plane Block in Posterior Cervical Spine Surgery
Posterior cervical spine surgery often requires a large posterior midline incision, resulting in poorly controlled postoperative pain, which arises from iatrogenic mechanical damage, intraoperative retraction, and resection to…
- Trial name
- NCT04974658
- Testing
- Inter-semispinal plane block
- Where
- 2 sites in Egypt
- Volunteers
- 52 people
- Sponsor
- Zagazig University
Regional Anaesthesia, Transversus Abdominis Plane Block
Prospective, Randomized Comparative Study Between an Anesthesiological, Ultrasound-guided, and a Laparoscopic, Landmark-based Application of a "Transversus Abdominis Plane (TAP) Block" Based on Postoperative Pain Perception, Postoperative Analgesic Requirement, and Procedure Duration
The Transversus Abdominis Plane Block (TAP) has become one of the most established and frequently performed trunk wall blocks for perioperative analgesia in abdominal surgical procedures.
- Trial name
- NCT06876155
- Testing
- Arm 1: The anaesthesiologically performed, ultrasound-guided, 4 quadrant-TAP block ( a combination of a lateral with a subcostal TAP block bilaterally), Arm2: The surgically performed, laparoscopic landmark-based assisted TAP block
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Sana Klinikum Offenbach
Postoperative Pain
Postoperative Analgesia in Laparoscopic Gynecological Surgeries
The aim of this study is to compare intraperitoneal instillation of magnesium sulfate versus sodium bicarbonate as an adjuvant to lidocaine 1% , on reducing postoperative pain in laparoscopic gynecological surgeries.
- Trial name
- NCT06491485
- Testing
- Group M (lidocaine with Magnesium sulfate), Group B (lidocaine with Sodium bicarbonate), Group C (lidocaine with saline)
- Volunteers
- 90 people
- Sponsor
- Assiut University
Postoperative Pain After Video Assisted Thoracic Surgery
Analgesic Effect of Intravenous Patient-Controlled Analgesia (IV PCA) Versus Paravertebral Block After Video Assisted Thoracic Surgery (VATS)
The purpose of this study is to compare the analgesic effect of paravertebral block with that of intravenous patient-controlled analgesia after video assisted thoracic surgery.
- Trial name
- NCT01538914
- Testing
- paravertebral block, PCA
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Seoul National University Hospital
Analgesic Rebound Headache
Detoxification and Treatment of Subjects With Medication Overuse Headache
The purpose of this study is to assess the benefits of almotriptan used as a transitional therapy and topiramate in subjects with medication overuse headaches (MOH.
- Trial name
- NCT00432549
- Testing
- Almotriptan, Topiramate
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The New England Center for Headache, P.C.
Knee Arthroscopy
Etoricoxib Versus Gabapentin for Knee Arthroscopy
To determine that when administered as part of a multimodal analgesic regimen, use of the new COX-2 antagonist etoricoxib (120 mg/day, per os) is more effective in improving postoperative pain management after knee arthroscopy…
- Trial name
- NCT00799149
- Testing
- Gabapentin, Etoricoxib, Sugar pill
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Meir Medical Center
Herpes Zoster, Neuralgia
Tolerability of Three Local Anesthetic Formulations in Conjunction With NGX-4010 for the Treatment of Neuropathic Pain
This study is a randomized, open-label multi-center evaluation of the tolerability of treatment with NGX-4010 in conjunction with pre-patch topical application of one of three 4% lidocaine-based local anesthetic products.
- Conditions
- Herpes Zoster, Neuralgia, Pain, HIV Infections
- Trial name
- NCT00082316
- Testing
- Capsaicin Dermal Patch
- Where
- 17 sites in United States
- Sponsor
- NeurogesX
Pain
Antagonistic Interaction CB1-paracetamol
Evaluation of an possible inhibiting effect of Rimonabant on the analgesic effect of Paracetamol in healthy volunteers
- Trial name
- NCT00750347
- Where
- 2 sites in France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Rotator Cuff Injuries, Shoulder Disease
Feasibility of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery
Postoperative pain remains undertreated with inadequate analgesic options. Opioids have well-known limitations for both individuals and society; single-injection and continuous peripheral nerve blocks provide intense analgesia…
- Conditions
- Rotator Cuff Injuries, Shoulder Disease, Hallux Valgus, Ankle Arthropathy
- Trial name
- NCT06818708
- Testing
- Experimental Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Postoperative Delirium, Postoperative Pain, Acute
Postoperative Delirium and Analgesia in Elderly Patients
This study aims to evaluate the effects of different postoperative analgesic approaches on postoperative delirium in elderly patients undergoing total knee arthroplasty.
- Trial name
- NCT07849517
- Testing
- adductor canal block and biFes block including bupivacain, Periarticular infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Pain, Postoperative Pain
Presternal Bupivacaine Plus Magnesium Sulfate Infusion After Cardiac Surgery
Effective pain relief after cardiac surgery has assumed importance with the introduction of fast track discharge protocols that requires early weaning from mechanical ventilation.
- Trial name
- NCT02731950
- Testing
- Magnesium Sulfate and Bupivacaine 0.125%
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Gallstones, Pain
Comparison of the Efficacy of Different Analgesic Strategies for Pain Control After Laparoscopic Cholecystectomy (LC)
The investigators collected 200 patients underwent safe uncomplicated laparoscopic cholecystectomy, then different strategies of pain control are used.
- Trial name
- Randomized (NCT07897435)
- Testing
- Low pneumoperitoneum, Local anaesthetic instillation to gallbladder bed
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post-operative Pain
Added Value of Local Clonidine for Spine Postoperative Pain Control, in Addition to Bupivacaine
The objective of this prospective randomized double-blind study is to evaluate the added analgesic value of clonidine to the conventional local bupivacaine wound infiltration in posterior spine surgery.
- Trial name
- NCT01902108
- Testing
- Bupivacaine, Clonidine
- Where
- Lebanon
- Volunteers
- 225 people
- Sponsor
- St Joseph University, Beirut, Lebanon
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