Clinical trials: Analgesic
Congenital Muscular Torticollis
Ultrasound Guided Intermediate Cervical Plexus Block for Congenital Muscular Torticollis
Congenital Muscular Torticollis (CMT) is a postural deformity of head and neck detected at birth or shortly after birth, primarily resulting from unilateral shortening of Sternocleidomastoid Muscle (SCM).
- Trial name
- NCT02651311
- Testing
- intermediate cervical plexus block, Fentanyl, Ibuprofen
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Ajou University School of Medicine
Pain Threshold, Mood
Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers
The following study is designed to determine the analgesic efficacy of smoked marijuana (0, 1.98, and 3.56% THC) and oral THC (0, 10, and 20 mg) in the Cold-Pressor Test (CPT), a laboratory model of pain which has predictive…
- Trial name
- NCT00743119
- Testing
- Inactive marijuana (0% THC), Low dose Dronabinol, High dose Dronabinol
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Fracture of Proximal End of Femur
Comparison of Analgesic Effectiveness of Intravenous Ketamine and Fentanyl for Spinal Anesthesia is Sitting Position in Patients With Proximal Femur Fracture
This is a prospective comparative study which will be conducted in patients with proximal femur fracture undergoing operative interventions under subarachnoid block in sitting position.
- Trial name
- NCT04418674
- Testing
- Ketamine, Fentanyl
- Where
- 2 sites in Nepal
- Volunteers
- 52 people
- Sponsor
- Jenny Bajracharya
Postoperative Pain
Sacral Erector Spinae Plane Block Effect on Post-Hemorrhoidectomy Pain
Hemorrhoids are commonly observed surgical conditions affecting the anorectal area, characterized by symptoms such as pain, bleeding, and the presence of a protruding mass from the anal opening.
- Trial name
- NCT05965674
- Testing
- Sacral Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Konya City Hospital
Lumbar Fixation Surgery
Evaluation Of Three Different Anagesic Techniques In Patients Undergoing Lumbar Fixation Surgery
Lumbar spinal stenosis is a degenerative condition characterized by the narrowing of the space surrounding the neurovascular structures of the lumbar vertebrae, resulting from age-related changes in the intervertebral discs…
- Trial name
- NCT06801574
- Testing
- Erector Spinae Plane Block, infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ataturk University
Colo-rectal Cancer
Does Omission of NSAIDs After Colorectal Cancer Operation Affect the Consumption of Opioids?
Patients undergoing an operation for colorectal cancer are normally treated with non-steroid-anti-inflammatory-drugs (NSAIDs) e.g. ibuprofen as pain medication after the operation.
- Trial name
- NCT04448652
- Testing
- NSAID
- Where
- Denmark
- Volunteers
- 502 people
- Sponsor
- Zealand University Hospital
Midazolam Premedication, Anxiety Preoperative
Assessing the Effectiveness of Midazolam Premedication
Pre-anesthetic dosing of midazolam is commonly used in many hospitals for the induction of anesthesia, but the effect is still controversial.
- Conditions
- Midazolam Premedication, Anxiety Preoperative, Premedication
- Trial name
- NCT03325335
- Testing
- Midazolam premedication, Remifentanil infusion, Propofol infusion
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Pusan National University Hospital
Osteoarthritis, Arthritis
Efficacy And Safety Study Of Tanezumab Subcutaneous Administration In Osteoarthritis - A Subcutaneous/Intravenous Bridging Study
This is an efficacy and safety study of 3 doses (2.5 mg, 5 mg and 10mg) of tanezumab administered subcutaneously versus placebo.
- Conditions
- Osteoarthritis, Arthritis, Pain
- Trial name
- NCT01089725
- Testing
- Tanezumab SC, Tanezumab IV
- Where
- 91 sites in United States
- Volunteers
- 385 people
- Sponsor
- Pfizer
Pain, Acute
Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients
The purpose of this study is to evaluate the analgesic effects of cannabidiol for patients who have undergone simple tooth extraction.
- Trial name
- SWAP (NCT04271917)
- Testing
- cannabidiol, acetaminophen 500mg and ibuprofen 200mg combo
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Tennessee
Anesthesia
Comparison of Analgesic Effect of Volatile Anesthetics
The purpose of this clinical trial is to compare analgesic effect of sevoflurane and desflurane at equal minimum alveolar concentrations using surgical pleth index.
- Trial name
- NCT02830243
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kangbuk Samsung Hospital
Pain
A Four-Arm Study Comparing the Analgesic Efficacy and Safety of Tramadol Once a Day 100, 200 and 300 mg Versus Placebo for the Treatment of Pain Due to Osteoarthritis of the Knee (With 7-Day Follow-up)
The objective of this study is to compare the analgesic efficacy and safety of Tramadol Once a Day 100, 200, 300 mg and Placebo
- Trial name
- NCT00852917
- Testing
- Tramadol Once A Day
- Volunteers
- 552 people
- Sponsor
- Labopharm Inc.
Pain, Postoperative, Disability Physical
Effects of Interpectoral-Pectoserratus Plane Block After Breast Cancer Surgery
The aim of this study: It was aimed to observe the effects of intraoperative and preoperative PECS II block on postoperative pain, amount of analgesic use and shoulder joint range of motion in patients who underwent breast cancer…
- Conditions
- Pain, Postoperative, Disability Physical, Quality of Life
- Trial name
- NCT05568589
- Testing
- Preoperative Interpectoral - Pectoserratus Plane Block, Intraoperative Interpectoral - Pectoserratus Plane Block, Non Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Bakircay University
Pain
Bupivacaine Injections Into Uterosacral Ligaments During Robotic Assisted Total Hysterectomies
Will patients that receive injections of Marcaine into the uterine nerve via the uterosacral ligaments experience less pain postoperatively, need less narcotic pain medication and return to activities of daily living sooner.
- Trial name
- NCT02230735
- Testing
- Bipivacaine 0.5% with epinephrine, Normal Saline
- Where
- United States
- Sponsor
- Souza, Amanda, M.D.
Symptomatic Irreversible Pulpitis
Comparison of Preoperative Analgesics on the Efficacy of Inferior Alveolar Nerve Block.
The purpose of this study is to see how preoperative oral diclofenac sodium, piroxicam, and tramadol affects inferior alveolar nerve block efficacy during root canal treatment of mandibular molars with symptomatic irreversible…
- Trial name
- NCT05488925
- Testing
- Vitamin E, Diclofenac Sodium, Piroxicam
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Farjad Zafar
Pain
The Use of a Digital Application for Reporting Pain and Pain Management in Home Hospice
Poor adherence to pain management and high pain intensity associated with serious, advanced illness is a major public health concern.
- Trial name
- ePainSupport (NCT04869085)
- Testing
- e-PainSupport
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Periapical Abscess
Comparison of Two Combinations of Opioid and Non-opioid Analgesics for Acute Periradicular Abscess
Aim: The aim of this study was to compare the analgesic efficacy of two combinations of opioid and non-opioid analgesics for acute periradicular abscesses.
- Trial name
- NCT02750696
- Testing
- Fixed-dose oral tablet of codeine/ acetaminophen every 4 hours for 3 days, Fixed-dose oral tablet of tramadol/ acetaminophen every 4 hours for 3 days
- Volunteers
- 27 people
- Sponsor
- Federal University of Rio Grande do Sul
Osteoarthritis, Knee Arthritis Osteoarthritis
The Effect of Two Different Analgesic Methods on QoR-40 Score in Primary Unilateral Knee Arthroplasties
Total knee arthroplasty (TKA) is a very common operation that increases in frequency with advancing age. Similar to other surgical procedures, strategies are being developed to minimize morbidity and mortality while allowing for…
- Conditions
- Osteoarthritis, Knee Arthritis Osteoarthritis, Knee Arthroplasty, Total
- Trial name
- NCT07236073
- Testing
- PRİMER TEK TARAFLI DİZ ARTOPLASTİSİNDE İKİ FARKLI ANALJEZİK YÖNTEMİ, knee replacement
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Drug Use Disorders
Treatment Outcomes Among Patients With Prescription Narcotic Drug Use Disorder
This study follows up patients who receive standard treatment for prescription narcotic drug use disorder, including opioids, benzodiazepines, and benzodiazepine-like drugs (z-drugs), at a specialized addiction service.
- Trial name
- TAPE (NCT03713983)
- Testing
- Observational study
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Johan Franck
Hip Surgery, Postoperative Analgesia
Postoperative Analgesic Efficacy of PENG and QLB Blocks in Hip Surgeries
This prospective, randomized, single-blinded study compares the postoperative analgesic efficacy of the Pericapsular Nerve Group (PENG) block and Quadratus Lumborum Block (QLB) in hip surgeries under spinal anesthesia.
- Trial name
- PENG vs QLB (NCT06653894)
- Testing
- PENG block with 0.25% bupivacaine., anterior quadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Intubation
Postoperative Analgesic Requirements for the ProSeal Laryngeal Mask Airway Versus the Tracheal Tube in Females Undergoing Gynecological Laparoscopic Surgery
The ProSeal laryngeal mask airway is a relatively new airway device with a modified cuff to increase the seal and a drain tube to provide a channel for regurgitated fluid, prevention of gastric insufflation and insertion of a…
- Trial name
- NCT00402870
- Testing
- ProSeal LMA, ProSeal LMA, Tracheal Tube
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
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