Clinical trials: Analgesic
Gynecological Laparoscopic Surgery, General Anesthetic
Effects and Safety of Oliceridine in Anesthesia Induction:A Randomised Controlled Trial
to investigate whether oliceridine is safe and effective for induction of anesthesia by comparing henodynamic changes before and after endotracheal intubation with sufentanil
- Conditions
- Gynecological Laparoscopic Surgery, General Anesthetic, Intubation
- Trial name
- NCT07372209
- Testing
- Oliceridine, Sufentanil
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tangshan Maternal and Child Health Hospital
Cholecystitis, Cholecystitis, Acute
EOIB for Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy, while less painful compared to conventional methods, is still a surgery that can cause significant pain for patients.
- Conditions
- Cholecystitis, Cholecystitis, Acute, Cholecystitis, Chronic, Cholecystitis; Gallstone
- Trial name
- NCT06656299
- Testing
- ultrasound guided external oblique intercostal plane block, Bupivacaine injection, paracetamol, tramadol, and ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Gallbladder Diseases
Sugammadex on Remifentanil Ce for Preventing Emergence Cough in Female
The purpose of this study is to investigate the optimal Ce of remifentanil for preventing emergence cough following extubation during general anesthesia in female who are reversed with sugammadex or neostigmine.
- Trial name
- NCT04407078
- Testing
- Sugammadex Injectable Product, Neostigmine Injectable Product
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ajou University School of Medicine
Post Operative Pain
Post-Operative Analgesic Efficacy Of Ultrasound Guided Pericapsular Nerve Group Block Versus Combined Suprascapular And Axillary (Circumflex) Nerve Block For Patients Undergoing Shoulder Arthroscopy
Recently, the Combined suprascapular nerve block and axillary nerve block (SSNB+ANB) was proposed to provide anesthesia and postoperative analgesia for shoulder surgery as a safe alternative to interscalene block.
- Trial name
- NCT05791058
- Testing
- ultrasound guided pericapsular nerve group shoulder block, ultrasound guided suprascapular and axillary nerve block, general anesthesia without nerve block
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Pain, Postoperative
the Role of Popliteal Plexus Block in Pain Management After Anterior Cruciate Ligament Reconstruction.
Anterior cruciate ligament (ACL) injury is traumatic and debilitating and is typically repaired using an arthroscopic technique performed as an outpatient surgical procedure.
- Trial name
- NCT04020133
- Testing
- saphenous nerve block, popliteal plexus block, Plain bupivacaine
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Fayoum University Hospital
Anesthesia
Comparison Between Two Ultrasound Technologies for Ultrasound-guided Catheter Placement in Regional Anesthesia
The use of ultrasound imaging techniques in regional anaesthesia is rapidly becoming an area of increasing interest. It represents one of the largest changes that the field of regional anaesthesia has seen.
- Trial name
- eZono (NCT01122693)
- Testing
- eZono - high-quality 2D ultrasound images, standard 2D ultrasound images
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Charite University, Berlin, Germany
Pain Threshold, Conscious Sedation
Correlation Between Pain Threshold and Analgesic Consumption in Transvaginal Oocyte Aspiration Patients
Nowadays, in vitro fertilization (IVF) is an important component of modern infertility treatment. One of the critical stages of the IVF process is oocyte (egg) retrieval, which requires both anesthesia and analgesia; this…
- Conditions
- Pain Threshold, Conscious Sedation, Oocyte Retrieval
- Trial name
- NCT07262216
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Burcu ayvazoğlu
Lumbar Disc Disease, Spinal Fusion
Analgesic Effects of Perioperative Propranolol Administration for Spine Surgery
The purpose of this study is to determine if treatment with low-dose oral propranolol in the days before and after surgery decrease postoperative pain and improve pain scores.
- Conditions
- Lumbar Disc Disease, Spinal Fusion, Degenerative Disc Disease
- Trial name
- NCT04421209
- Testing
- Propranolol Hcl 40mg Tab
- Where
- United States
- Sponsor
- Duke University
Peripheral Neuropathy
Analgesic Effect of Accelerated Repetitive Transcranial Magnetic Stimulation in Neuropathic Pain
Peripheral neuropathy is a frequent condition, commonly associated with pain. Repetitive Transcranial Magnetic Stimulation (rTMS) is a noninvasive method of modulation of brain plasticity and is regarded as one of alternative…
- Trial name
- NCT05295498
- Testing
- Active repetitive transcranial magnetic stimulation
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Jakub Antczak
Analgesic Adverse Reaction, Nociceptive Pain
The Correlation Between Sevoflurane and qNOX
This study purpose to observation the sevoflurane analgesia effect, and using nociception real-time monitoring NOX to test the correlation between the sevoflurane and NOX index.
- Conditions
- Analgesic Adverse Reaction, Nociceptive Pain, Inhalation; Vapor
- Trial name
- NCT03665792
- Testing
- nociception index qNOX
- Where
- China
- Volunteers
- 58 people
- Sponsor
- China International Neuroscience Institution
Pain, Osteoarthritis, Hip
Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee
This clinical trial tests the pain relieving effectiveness of OROS hydromorphone, a once-daily formulation of a strong opioid against placebo in patients, who are suffering from pain due to osteoarthritis of the hip or the knee…
- Conditions
- Pain, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT00980798
- Testing
- OROS hydromorphone HCl
- Where
- 12 sites in Czechia, Romania and 2 more
- Volunteers
- 288 people
- Sponsor
- Janssen-Cilag International NV
Postoperative Nausea, Adverse Effects
Safety and Tolerability of Controlled-release Oxycodone on Postoperative Pain in Oncologic Head and Neck Surgery
The hypothesis of this study is that controlled release oxycodone can be safe and well tolerated for the control of postoperative pain in surgery for head and neck cancer.
- Conditions
- Postoperative Nausea, Adverse Effects, Opioid Analgesic Adverse Reaction, Pain
- Trial name
- NCT01834898
- Testing
- Controlled-release oxycodone
- Where
- Brazil
- Volunteers
- 83 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Shoulder Injury
Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery
Pre-operative perineural injection of dexamethasone mixed with local anesthetic in peripheral nerve blockade for orthopedic surgery has been shown to prolong the length of analgesia, improve visual analog pain scores, decrease…
- Trial name
- NCT01450007
- Testing
- Ropivacaine, Dexamethasone, Normal saline
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Mayo Clinic
Gallbladder Diseases
Sugammadex on Remifentanil Ce for Preventing Emergence Cough in Male
The primary purpose of this study is to investigate the optimal Ce of remifentanil for preventing emergence cough following extubation during general anesthesia in male patients who are reversed with sugammadex or neostigmine.
- Trial name
- NCT03583021
- Testing
- Sugammadex Injectable Product, Neostigmine Injectable Product
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Ajou University School of Medicine
Post Operative Pain, Acute, Sedation Score
Patient Control Epidural Versus Conventional Epidural.
As one of the complications of THR is post operative pain, which usually requires epidural catheter insertion. We are comparing the effect of patient control epidural versus conventional epidural for patient's satisfaction.
- Conditions
- Post Operative Pain, Acute, Sedation Score, Degree of Motor Block, Length of Hospital Stay
- Trial name
- NCT06721000
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Malignant Neoplasm of Breast
Analgesic Effects of Ultrasound Guided PEC Blocks on Analgesic Opioid Consumption of Cancer Surgery Patients
Examining the analgesic effect of ultrasound guided Pectoral Blocks on analgesic opioid consumption after surgical removal of breast tissue.
- Trial name
- NCT02495363
- Testing
- PECS Block, Bupivacaine 0.25-0.5%
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rabin Medical Center
Pain, Anxiety
Comparison of Different Methods for Reducing Pain From Influenza Vaccine Injections
The purpose of this study is to compare four different analgesic strategies in adults undergoing routine influenza immunization
- Trial name
- NCT01006187
- Testing
- Liposomal lidocaine, Vapocoolant spray, Rubbing adjacent to the injection site
- Where
- Canada
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Ventral Hernia, Inguinal Hernia
Methocarbamol in Ventral and Inguinal HR
The purpose of this study is to gather information on methocarbamol as a pain management treatment for ventral or inguinal hernia repair.
- Trial name
- NCT05388929
- Testing
- Methocarbamol, Standard Opioid, Standard opioid plus methocarbamol
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Prisma Health-Upstate
Cancer-related Problem/Condition
Magnesium Associated With Morphine for Cancer Pain Relief
This study is an evaluation of the analgesic effect of magnesium associated with morphine in patients with cancer pain.
- Trial name
- NCT01541111
- Testing
- Magnesiun
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Pain, Pain Syndrome
Integrating Pain-CBT Into an mHealth Analgesic Support Intervention for Patients With Chronic Pain From Advanced Cancers
Smartphone Technology to Alleviate Malignant Pain (STAMP) + Cognitive Behavioral Therapy for Pain (STAMP+CBT) The purpose of the study is to develop and refine the mHealth pain-CBT app intervention and carry out a randomized…
- Conditions
- Pain, Pain Syndrome, Advanced Cancer
- Trial name
- NCT06722014
- Testing
- STAMP + CBT, Digital Cancer Pain Education Packet
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Dana-Farber Cancer Institute
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