Clinical trials: Analgesic Effect
Cancer, Pain
Pro-self Pain Management in Norway
The main aim of this study is to evaluate whether a patient education programme on cancer pain management compared to standard care decreases pain and increases patients quality of life.
- Trial name
- Pro-self (NCT00760305)
- Testing
- Pro self pain control programme
- Where
- Norway
- Volunteers
- 167 people
- Sponsor
- Oslo University Hospital
Irreversible Pulpitis
Analgesic Effect of Anahil and Ibuprofen on Pain After Root Canal Therapy in Patients With Pulpitis of the Molars in Qazvin(a City in Iran)
Hypothesis: 0: The analgesic effect of Ibuprofen and Anahil would be the same in reducing the pain after root canal therapy. 1: Ibuprofen shows higher potency to reduce the pain after root canal therapy.
- Trial name
- NCT05349929
- Testing
- Gelofen (generic name of Ibuprofen in Iran), Anahil ( generic name of Bromelain in Iran), Root Canal Therapy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Qazvin University Of Medical Sciences
Pain
Evaluation of the Analgesic Effect of Music Therapy in Critically Ill Patients During Potentially Painful Nursing Procedures: a Pilot Study
Pain is a common problem encountered in about 60 % of critically ill patients who can communicate. Its occurrence can be related to several causes, mainly dominated by invasive procedures.
- Trial name
- Painkiller (NCT02883959)
- Testing
- music therapy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Versailles Hospital
Fentanyl Analgesia
Analgesic Effect and Plasma Concentration of Epidural Versus Intravenous Fentanyl
CONTEXT AND OBJECTIVE: Controversies exist regarding the site of action of Fentanyl after epidural injection. The objective of this investigation was to compare the analgesic effect of epidural and intravenous Fentanyl for lower…
- Trial name
- FTN (NCT00635986)
- Testing
- Fentanyl
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Pain
Effect of Topical and Oral Diclofenac on Pain Related to Intravitreal Injections
The analgestic efffect of Diclofenac Sodium 0.1% Eye Drops and a combination of Diclofenac Sodium 0.1% Eye Drops and oral Diclofenac Sodium sustained-release 75mg tablets on pain related to intravitreal injections will be…
- Trial name
- NCT02837770
- Testing
- Diclofenac Eye Drops, Pacebo pill, Oral Diclofenac
- Where
- Greece
- Volunteers
- 76 people
- Sponsor
- University Hospital of Patras
Post Operative Pain, Inguinal Hernia
Comparison of Two Different Analgesic Regional Block Techniques in Pediatric Patients Undergoing a Hernia Repair
Lower abdominal operations; especially inguinal hernia repairs are one of the most frequently performed operations in the daily practice of pediatric surgeries.Regional anesthesia techniques are frequently and effectively used…
- Trial name
- NCT05896072
- Testing
- Erector Spinae Plane Block, Caudal Block
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Abant Izzet Baysal University
Diabetic Neuropathic Pain
A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain
People with diabetes can, over time develop nerve damage throughout the body with symptoms such as pain, tingling, or numbness (loss of feeling) in the hands, arms, feet and legs.
- Trial name
- NCT01345045
- Testing
- ABT-639, pregabalin
- Where
- 35 sites in United States, Czechia and 3 more
- Volunteers
- 193 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Pain, Postoperative
Analgesic Efficacy of Plan Blocks in Laparoscopic Hysterectomies
Hysterectomy is the most common major intervention in gynecology after cesarean section. Indications include myoma uteri, abnormal uterine bleeding, cervical intraepithelial neoplasia, chronic pelvic pain, uterine uteri, operated…
- Trial name
- NCT05925972
- Testing
- Plane block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Video Assisted Thoracoscopic Surgery, Postoperative Analgesia
Serratus Posterior Superior Intekcostal Plane Block vs Serratus Anterior Plane Block for Postoperative Analgesia in VATS: A Randomized Trial"
Thoracotomy is known as one of the most painful surgical procedures, with up to 65% of patients developing chronic post-thoracotomy pain syndrome (PTPS), and approximately 10% experiencing pain that significantly impacts quality…
- Trial name
- NCT07020624
- Testing
- SAPB, SPSIPB
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Samsun University
Postoperative Complications
Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?
the investigators aim is to investigate and explore the effect 10 mg morphine added to local anesthetics in serratus anterior plane block for post mastectomy pain management after modified radical mastectomy in patients with…
- Trial name
- NCT02962024
- Testing
- Morphine Sulfate, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fatma Adel El sherif,MD
Sepsis
Effect of Remazolam Besylate Combined With Remifentanil Analgesic Sedation on the Prognosis of Patients With Sepsis
In this study, midazolam was used as a control to investigate the effect of remazolam besylate combined with remifentanil on analgesia and sedation in patients with mechanical ventilation of sepsis on the prognosis of patients…
- Trial name
- NCT06731088
- Testing
- Midazolam, Remazolam besylate
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Abdominal Surgery
Study To Check The Analgesic And Anti-Inflammatory Effects Of Atorvastatin In Patients Undergoing Abdominal Surgery
The study is planned to check the analgesic and anti-inflammatory properties of Atorvastatin in patients who will be undergoing abdominal surgery under spinal anesthesia.
- Trial name
- A4S (NCT00902967)
- Testing
- Atorvastatin
- Where
- India
- Volunteers
- 40 people
- Sponsor
- B. J. Medical College, Pune
Opioid Use, Post Operative Pain
Comparing Intrathecal Morphine With Erector Spina Plane Block in Open Gastrectomy Surgery
Open gastrectomy causes severe postoperative pain due to wide surgical incisions, retraction of the abdominal wall and direct manipulation of the visceral organs.
- Conditions
- Opioid Use, Post Operative Pain, Pain Assessment Scales
- Trial name
- NCT05706285
- Testing
- Regional Block Comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Marmara University
Acute Pain
CoPainHell: The Analgesic Effect of Alcohol and Music
The study is a 2x2 randomized crossover study. Participants are randomized to listen to one of two music tracks: "Orinoco Flow" by Enya or "Raining Blood" by Slayer.
- Trial name
- CPH (NCT06471985)
- Testing
- Music and pain
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Eske Kvanner Aasvang
Postoperative Anxiety, Pain
The Effect of Operating Room Nurse Visit Prior to Cardiac Surgery on Patients's Anxiety, Pain and Analgesic Use
This study was planned as a quasi-experimental pre-test post-test control group design in non-randomized groups to determine the effect of the preoperative visit by the operating room nurse on the postoperative anxiety level and…
- Conditions
- Postoperative Anxiety, Pain, Postoperative Pain Management
- Trial name
- NCT04525963
- Testing
- Preoperative visit of the operating room nurse and patient education
- Volunteers
- 64 people
- Sponsor
- Nurgül Arpag
Pain, Postoperative
Safety and Efficacy Study of KAI-1678 to Treat Subjects With Postoperative Pain
The purpose of this study is to determine whether KAI-1678 is effective in the treatment of postoperative pain following total hip or total knee replacement.
- Trial name
- NCT01015235
- Testing
- KAI-1678, Ketorolac Tromethamine
- Where
- New Zealand
- Volunteers
- 90 people
- Sponsor
- KAI Pharmaceuticals
Rehabilitation, Postoperative Pain
Effect of Dezocine Combined With Sufentanil on the Quality of Postoperative Recovery and Analgesic Effect in Patients Undergoing Thoracic Surgery
The goal of this clinical trial is to evaluate the effect of dezocine combined with sufentanil on postoperative recovery quality and analgesic effect in patients undergoing thoracic surgery.
- Trial name
- NCT06439368
- Testing
- Dezocine
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Yangtze River Pharmaceutical Group Co., Ltd.
Central Pain Syndrome
Comparison of rTMS and H Coil in Neuropathic Pain
rTMS of the motor cortex is an increasingly established analgesic technique for the treatment of neuropathic pain. However its efficacy is generally modest.
- Trial name
- HNEP (NCT03370107)
- Testing
- rTMS
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Hospital Ambroise Paré Paris
Pain, Postoperative
Does Pre and Postoperative Dextromethorphan Reduce Post-tonsillectomy Pain in Children?
With Institutional ethics board and Health Canada approval, pediatric patients (ages 3-12) undergoing tonsillectomy or adenotonsillectomy (under standardized anesthesia) will be randomized to receive dextromethorphan hydrobromide…
- Trial name
- NCT02727491
- Testing
- Dextromethorphan
- Volunteers
- 85 people
- Sponsor
- Dr. Rachel Rooney
Neonates Analgesy
Analgesic Effect of Maternal Breast Milk Odor in Preterm Neonates: a Randomised Controlled Trial
Objective : To assess the analgesic effect of maternal breast milk odor in preterm neonates Design : A prospective, randomised, controlled, double blinded, monocentric trial.
- Trial name
- NCT02381691
- Testing
- maternal breast milk odor, no odor
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille