Clinical trials: Analgesic Effect
Pain, Post-operative Pain Control
Effect of Lidocaine in Reducing Opioids Requirement in Day Care Surgery
1. *Reduced opioid consumption 2. *Decreased pain scores 3. *Fewer opioid-related side effects 4. *Improved patient satisfaction
- Conditions
- Pain, Post-operative Pain Control, Post-operative Pain
- Trial name
- NCT06717672
- Testing
- Lidocaine 2% without vessel constrictor, Normal Saline
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Liaquat National Hospital & Medical College
Postoperative Pain
Effect of Intravenous Dexmedetomidine on Analgesic Duration of Infraclavicular Block
The study will evaluate the effect of Dexmedetomidine sedation on the duration of infraclavicular block in patients scheduled for surgery of elbow, forearm and/or hand.
- Trial name
- NCT01981369
- Testing
- Dexmedetomidine, Propofol, Infraclavicular block
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Dexmedetomidine Analgesia, Knee Surgery
Intravenous Regional Analgesia of Dexmedetomidine
Dexmedetomidine is a highly selective α₂-adrenergic receptor agonist that exerts its effects by inhibiting the release of norepinephrine at presynaptic nerve terminals, leading to reduced sympathetic activity; This mechanism…
- Trial name
- Dexmedetomidin (NCT07131579)
- Testing
- Normal Saline, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Analgesics, Opioid, Anesthesia; Adverse Effect
Comparison of Total Intravenous Anesthesia and Inhalational Anesthesia in Opioid-Free Anesthesia for Bariatric Surgery: A Randomized Controlled Trial
Total intravenous general anesthesia and combined general anesthesia are recognized methods used during anesthesia. They allow you to effectively control pain and reduce the number of complications associated with taking large…
- Trial name
- NCT06390046
- Testing
- TIVA versus Inhalation
- Where
- Poland
- Volunteers
- 280 people
- Sponsor
- Jagiellonian University
Pericapsular Nerve Group Block, Lateral Femoral Cutaneous Nerve Block
The Analgesic Effect of Pericapsular Nerve Group Block With Lateral Femoral Cutaneous Nerve Block and Pericapsular Nerve Group Block With Supra-inguinal Fascia Iliaca Block in Hip Hemiarthroplasty
The aim of this study is to investigate the efficiency of preoperative and post-operative analgesia by pericapsular nerve group block (PENG) block with supra-inguinal fascia iliaca block (SIFIC) block compared with PENG block…
- Conditions
- Pericapsular Nerve Group Block, Lateral Femoral Cutaneous Nerve Block, Supra-inguinal Fascia Iliaca Block, Hip Hemiarthroplasty
- Trial name
- NCT06577103
- Testing
- Pericapsular nerve group block (PENG) with supra-inguinal fascia iliaca block (SIFIC), Pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve block (LFCN)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Carpal Tunnel Syndrome
Effects of Cerebral & Peripheral Electrical Stimulation on Pain and Function in CTS
This is a randomized, double-blind, multi-center, factorial clinical trial to study the effectiveness of cerebral and peripheral electrical stimulation on pain and functional limitations associated with carpal tunnel syndrome…
- Trial name
- DCS-ENS-CTS (NCT04092088)
- Testing
- tDCS-r, TENS-r, tDCS-s
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Pain, Postoperative, Disability Physical
Effects of Interpectoral-Pectoserratus Plane Block After Breast Cancer Surgery
The aim of this study: It was aimed to observe the effects of intraoperative and preoperative PECS II block on postoperative pain, amount of analgesic use and shoulder joint range of motion in patients who underwent breast cancer…
- Conditions
- Pain, Postoperative, Disability Physical, Quality of Life
- Trial name
- NCT05568589
- Testing
- Preoperative Interpectoral - Pectoserratus Plane Block, Intraoperative Interpectoral - Pectoserratus Plane Block, Non Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Bakircay University
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pain, Postoperative
Analgesic Efficacy of Two Adjuvants During Spinal Anaesthesia.
: Pain modulation is very important after operation, particularly for women who undergo caesarean section. A pain-free postoperative period is essential following a caesarean section so new mothers may care for and bond with…
- Trial name
- NCT03458078
- Testing
- Saline Solution, Magnesium Sulfate, Midazolam 5 MG/ML Injection
- Where
- 2 sites in Tunisia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre de Maternité de Monastir
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Pain
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1940
The primary aim of this study is to investigate if AZD1940 can relieve the pain induced by the surgical removal of one lower wisdom-tooth.
- Trial name
- NCT00659490
- Testing
- AZD1940, Naproxen
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Gonarthrosis
Role of Femoral Nerve Block on Prevention of Postoperative Deep Venous Thromboembolism
To investigate whether preemptive analgesic of femoral nerve block could prevent deep venous thromboembolism due to inhibiting the excessive release of neutrophil elastase and inflammatory cytokines.
- Trial name
- NCT02411097
- Testing
- femoral nerve block
- Where
- China
- Volunteers
- 120 people
- Sponsor
- General Hospital of Ningxia Medical University
Abdominal Pain/ Discomfort, Irritable Bowel Syndrome
The Mechanism Underlying the Analgesic Effect of the Music of IBS Pain
The proposed pilot study aims to assess the underlying mechanisms of the MBI on IBS pain and the feasibility of using novel technology in the outcome measurements.
- Trial name
- NCT06706778
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Lower Abdominal Surgery
Comparison Between the Quadratus Lumborum Block ,Erector Spinae Plane Block in Lower Abdominal Surgery
the purpose of study is comparison between the analgesic effect of two techniques in adult lower abdominal surgeries
- Trial name
- NCT05524038
- Testing
- Bupivacaine Hydrochloride, Ultrasound device, Dexamethasone
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Fayoum University Hospital
Impacted Third Molar Tooth
Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model
Ginger contains constituents with pharmacological properties similar to the novel class of dual-acting NSAIDs. Compounds in this class inhibit arachidonic acid metabolism via the cyclooxygenase (COX) and lipooxygenase (LOX)…
- Trial name
- GPE (NCT01429935)
- Testing
- Ginger powder, Ibuprofen
- Where
- 2 sites in Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Qazvin University Of Medical Sciences
Chemotherapy-induced Peripheral Neuropathy
Neural and Immune Correlates of CIPN and Possible Analgesic Effect of Non-invasive Motor Cortex Stimulation
Over half of cancer patients receiving common chemotherapy treatments experience painful nerve damage called chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NIBS4CIPN (NCT06522685)
- Testing
- transcranial direct current stimulation Soterix REMOTE 1x1 miniCT
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Morgan State University
Acute Pain
Immune Response of Caudally Administrated Tramadol In Pediatric Lower Abdominal Surgery
Management of acute pain is one of the most important tasks of perioperative pediatric anesthesia. The alleviation of pain has been defined by the Society of Pediatric Anesthesia, on its 15th annual meeting as a basic human…
- Trial name
- NCT02703415
- Testing
- Bupivacaine, Tramadol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Procedural Pain
Analgesic Effect of Low Level Laser for Procedural Pain in Newborn Infants
Neonates undergo several painful procedures and these pain experiences can alter clinical outcome and behavior. The investigators aim to investigate the analgesic effect of low level laser for procedural pain during heel lancing…
- Trial name
- NCT03268148
- Testing
- LaserPen
- Where
- Taiwan
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pain, Cancer
Study on Analgesia of GIC-1001 & GIC-1002 on Visceral Pain, Rectal Sensory Threshold Using the Barostat Method
This study evaluates colonic analgesia by comparing two novel formulations, GIC-1001 and GIC-1002 with placebo using a barostat distender.
- Conditions
- Pain, Cancer, Colonic Disease
- Trial name
- NCT02276768
- Testing
- GIC-1001 375 mg TID, GIC-1001 500 mg TID, GIC-1002 345 mg TID (equimolar to GIC-1001 375 mg TID)
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- gicare Pharma Inc.
Heated Humidified Carbon Dioxide in Gynaecological Laparoscopic Surgery
Standard Carbon Dioxide Gas Versus Heated Humidified Gas in Gynaecological Laparoscopy
To establish if heated humidified carbon dioxide gas improves pain scores as well as nausea and analgesic requirements in post operative patients compared to standard cold carbon dioxide.
- Trial name
- NCT02319902
- Testing
- Standard cold carbon dioxide gas, Heated humidified carbon dioxide gas
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fevzi Shakir