Clinical trials: Analgesic Effect
Anesthesia, Regional Anesthesia
Analgesic Effect of Bilateral Subcostal Quadratus Lumborum Block in Laparoscopic Colorectal Surgery
Effective postoperative pain management is crucial for promoting early recovery and ambulation following laparoscopic colorectal surgery.
- Conditions
- Anesthesia, Regional Anesthesia, Post Operative Pain
- Trial name
- NCT06653439
- Testing
- Bilateral ultrasound guided Subcostal Quadratus Lumborum Block, Control, IV morphine PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Burns, Pain, Burning
Effects of Applying Streaming Media on Reducing Pain in Patient With Second-degree Burn During Changing Dressing
During the acute phase of burn injuries, the focus for patients is primarily on wound pain and infection care. Patients often describe the pain during dressing changes as a sharp, stabbing sensation.
- Conditions
- Burns, Pain, Burning, Anxiety
- Trial name
- NCT06076031
- Testing
- Streaming Media
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chiayi Christian Hospital
Percutaneous Electrolysis, Pain
Analgesic Mechanisms of Percutaneous Electrolysis
Percutaneous electrolysis is based on the application of a galvanic current through an acupuncture needle. The underlying mechanisms that explain the efficacy of this technique are not completely well understood.
- Conditions
- Percutaneous Electrolysis, Pain, Analgesia, Pain Modulation
- Trial name
- NCT05097937
- Testing
- Low intensity percutaneous electrolysis, High intensity percutaneous electrolysis
- Where
- Spain
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Myotoxicity
CPK Levels After LC and Association With Analgesic Modalities
Regional anesthesia and analgesia technics are widely and securely used during general surgery procedures. Interfascial plane blocks are the latest used ones for analgesia.
- Trial name
- NCT06508177
- Testing
- İnterfascial plane block, Standart analgesia plan
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun University
Sacral Erector Spinae, Penile And Caudal Block For Pain Relief After Hypospadius Surgery
Sacral Erector Spinae,Penile and Caudal Block for Pain Relief After Hypospadias Surgery
Caudal anaesthesia is recommended for most surgical procedures of the lower part of the body, mainly below the umbilicus, including inguinal hernia repair, urinary and digestive tract surgery and orthopaedic procedures on the…
- Trial name
- NCT05307653
- Testing
- Penile block, Erector spinea plain block, Caudal block
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Tanta University
Hand Injuries
Analgesic Effects of Gabapentin and Paracetamol
This research is about the effects of drug gabapentin; which is an amino acid that is structurally similar to neurotransmitter GABA.
- Trial name
- GABA (NCT04068506)
- Testing
- Gabapentin 600 mg Tab
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Dow University of Health Sciences
Shoulder Arthroscopy, Postoperative Pain
Magnesium Sulfate With Standard Combined Costoclavicular-Suprascapular Block for Pain Relief After Shoulder Arthroscopy.
This study aims to evaluate whether adding magnesium sulfate to a combined costoclavicular and suprascapular nerve block improves postoperative pain control in patients undergoing shoulder arthroscopy.
- Conditions
- Shoulder Arthroscopy, Postoperative Pain, Regional Anesthesia
- Trial name
- CCSS-Mg (NCT07798115)
- Testing
- Bupivacaine, Magnesium sulfate (MgSO4), Normal Saline (NS)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Assiut University
Abdominal Hysterectomy
The Effect of Two Different Analgesic Techniques on Postoperative Recovery Quality
Hysterectomy is one of the most frequently performed surgical procedures after Caesarean section in many countries of the world and involves the removal of the uterine corpus with or without the cervix (total hysterectomy) or…
- Trial name
- NCT06766994
- Testing
- intrathecal morphine, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Pain
Impact of Naloxone on the Analgesic Effect of Paracetamol in Healthy Volunteers
The aim of this study is to check if Naloxone induce an inhibiting effect on the analgesic effect of paracetamol in healthy volunteer, using evoked potentials.
- Trial name
- NCT00750048
- Testing
- Naloxone and paracetamol
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Inguinal Hernia
Comparison of Analgesic Effect of Magnesium Added to Ropivacaine and Ropivacaine Alone in Caudal Analgesia on Postoperative Pain Control in Pediatric Patients Undergoing Inguinal Hernia Repair
A caudal anesthesia is one of the most commonly used technique providing intra and postoperative analgesia in pediatric low abdominal surgery.
- Trial name
- NCT01679353
- Testing
- caudal block, normal saline 0.5ml
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women in spontaneous labor with whom analgesia is maintained with a combined spinal epidural (CSE)…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982838
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Open Gastrectomy With Gastric Cancer
Comparison of Analgesic Effects According to Patient-controlled Epidural Analgesia Modes in Patients Undergoing Open Gastrectomy
Epidural PCA (patient controlled analgesia) for post-operative pain management are effective analgesic method. It is widely used in the postoperative pain management for decades.
- Trial name
- NCT03430440
- Testing
- Apply CIPKA mode, Conventional mode
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Yonsei University
Dysmenorrhea
Multi-center Clinical Trials of Sanjie Analgesic Capsule in Treating Endometriosis
It is a multi-center, double -blind, placebo -controlled, randomized post-marketing study in Chinese subjects with endometriosis-associated pain to assess treatment effect and safety in the subjects treated with Sanjie Analgesic…
- Trial name
- NCT02031523
- Testing
- Sanjie analgesic capsule
- Where
- 14 sites in China
- Volunteers
- 400 people
- Sponsor
- Jiangsu Kanion Pharmaceutical Co., Ltd
Post-thoracotomy Pain Syndrome
Effects of Dexmedetomidine Used in Continuous Thoracic Paravertebral Blocks
The purpose of this study is to explore the effectiveness of dexmedetomidine as an adjunctive analgesic, used in ultrasound-guided continuous thoracic paravertebral blocks for Post-thoracotomy Pain Syndrome(PTPS).
- Trial name
- NCT02619513
- Testing
- Dexmedetomidine, Ropivacaine, Mindray M7 series
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Weifeng Tu
Pain, Shoulder
The Effect of Hot Application on Post Laparoscopic Shoulder Pain and Analgesic Use
The aim of this study; To evaluate the effect of hot application on postlaparoscopic shoulder pain and analgesic use in patients undergoing upper laparoscopic surgery in general surgery.
- Trial name
- NCT05334797
- Testing
- Local heat therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Multiple Myeloma, Neoplasm, Plasma Cell
Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma
This study will find the maximum tolerated dose (MTD) of CYNK-001 which contain NK cells derived from human placental CD34+ cells and culture-expanded. CYNK-001 cells will be given post Autologous Stem Cell Transplant (ASCT).
- Conditions
- Multiple Myeloma, Neoplasm, Plasma Cell, Neoplasms by Histologic Type, Neoplasms
- Trial name
- NCT04309084
- Testing
- CYNK-001
- Where
- 4 sites in United States
- Volunteers
- 29 people
- Sponsor
- Celularity Incorporated
Medial Compartment Knee Osteoarthritis
Study of How An Ankle Strap Changes Effects of Insole Treatment for Knee Osteoarthritis
The goal of this project is to assess the effects of an ankle strap on the effectiveness of a laterally-wedged insole with ankle strapping in reducing knee symptoms and improving static and dynamic lower limb biomechanics.
- Trial name
- NCT00331110
- Testing
- Laterally-Wedged Insole with Ankle Strapping, Laterally-Weged Insole
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Iowa
Aging, Pain
PK PD of the Enantiomers of Tramadol and O-desmethyltramadol in Elderly and Young Subjects
This study evaluates the pharmacokinetics and pharmacodynamics of the enantiomers of tramadol and O-desmethyltramadol (ODM) in generally healthy young and elderly adults.
- Trial name
- NCT02329561
- Testing
- Tramadol extended release 200 mg, CP/T
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Irriversible Pulpitis
Analyzing the Impact of Occlusal Reduction on the Pain Following Root Canal Therapy in Molar Teeth With and Without Pain in Turkish Patients.
Introduction: This study aimed to compare the intensity of postoperative pain after single-visit root canal treatment of symptomatic or asymptomatic teeth following occlusal reduction.
- Trial name
- NCT06953856
- Testing
- occlusal reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Patients Undergoing a Lumbar Slipped Disc Surgery
Co-analgesic Effects of Dexamethasone and Pregabalin After Lumbar Slipped Disc Surgery
The aim of the study is to show a decrease in postoperative pain during the first postoperative mobilization surgery lumbar disc herniation through a co-analgesia with a single dose of dexamethasone, pregabalin, or a combination…
- Trial name
- DEXA-PG-HD (NCT01811251)
- Testing
- Pregabaline (150mg), Dexamethasone (20mg/5ml; 0.2mg/kg)
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Clermont-Ferrand