Clinical trials: Analgesic Effect
Analgesia, Caffeine
Caffeine Intake Inrelation to Perioperative Analgesic Consumption
Caffeine is the most widely consumed psychoactive drug in the world. Natural sources of caffeine include coffee, tea, and chocolate.
- Trial name
- NCT05330754
- Testing
- Caffeine intake in mg
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Pediatrics
Effect of Intraoperative Remifentanil Infusion Rate on Postoperative Tolerance and Analgesic Consumption in Pediatric Laparoscopic Ureteroneocystostomy
Effect of intraoperative remifentanil infusion rate on postoperative tolerance and analgesic consumption in pediatric laparoscopic ureteroneocystostomy.
- Trial name
- NCT01147757
- Testing
- remifentanil
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Opioid Use Disorder
Mobile Peer Support for OUD Recovery
The COVID-19 pandemic puts individuals recovering from opioid use disorders (OUDs), an already vulnerable population, at increased risk of overdose due to decreased access to treatment, decreased social support, and increased…
- Trial name
- MPS (NCT05405712)
- Testing
- Mobile Phone App
- Where
- 2 sites in United States
- Volunteers
- 1,300 people
- Sponsor
- Brown University
Inguinal Hernia, Postoperative Pain
Comparing Erector Spinae Plane (ESP) and Transversus Abdominis Plane (TAP) Block in Inguinal Hernia
The Erectore Spinae Plane Block (ESP Block) is a recently described technique for regional anesthesia that has shown promising results in the treatment of pain after thoracic surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Anesthesia, Local, Anesthesia Complication
- Trial name
- TAPESP (NCT04750512)
- Testing
- ESP block, TAP block
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Ghielmini Enea
Scoliosis
Analgesic Effects of Gabapentin After Scoliosis Surgery in Children
The primary aim of this study is to determine whether the use of gabapentin will improve postoperative analgesia and reduce opioid consumption and side effects in children undergoing corrective spinal surgery for idiopathic…
- Trial name
- NCT00684112
- Testing
- Gabapentin
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- The Hospital for Sick Children
Pain Intensity Assessment, Pain Management
Studying Warmed Lidocaine for Increased Analgesic Effect During Intravitreal Injections
Investigating whether warmed lidocaine increases analgesic effect for intravitreal injections
- Trial name
- WarmLido (NCT06962709)
- Testing
- Warmed lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Missouri-Columbia
Post Operative Pain
Comparison of M-TAPA and TAP Blocks on Postoperative Analgesia in Laparoscopic Appendectomy Surgeries
The goal of this study is to compare the analgesic efficacy of M-TAPA block and TAP block in patients undergoing laparoscopic appendectomy surgeries
- Trial name
- NCT06483581
- Testing
- M-TAPA block with bupivacaine 25%, TAP block with bupivacaine 25%
- Volunteers
- 30 people
- Sponsor
- Cumhuriyet University
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Pain Measurement
Evaluation of Propranolol's Effect on Pain and Inflammation.
Previous studies have shown that the beta-adrenergic system plays a role in processing pain and the expression of hyperalgesia. Recent studies have investigated the analgesic effects, and potential anti-hyperalgesic effects…
- Trial name
- NCT01094574
- Testing
- Alfentanil, Propranolol
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Martin Angst
Post-operative Analgesia, Retrolaminar Block
Comparison Between Erector Spinae Plane Block And Retrolaminar Block In Patients Undergoing VATS.
Post-Video-assisted thoracoscopic surgery pain is a challenging clinical problem that may be associated with increased morbidity and mortality.
- Conditions
- Post-operative Analgesia, Retrolaminar Block, Erector Spinae Plan Block, VATS
- Trial name
- NCT06021327
- Testing
- Erector spinae plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Pain, Surgery
NSS-2 BRIDGE Device in Post-Operative Pain Management
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Conditions
- Acute Pain, Surgery, Abdominal Cancer
- Trial name
- NCT03555266
- Testing
- NSS-2 Bridge
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Jacques E. Chelly
Pain, Postoperative
Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
The purpose of this study is to evaluate the patient experience when using gabapentin with other pain control medications after posterior spinal fusion surgery for scoliosis in adolescents.
- Trial name
- NCT01977937
- Testing
- Gabapentin 250mg/5mL NDC:59762-5025-01, Simple Syrup
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Oregon Health and Science University
Fracture of Ankle
Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block
Patients scheduled to have foot and ankle surgery will typically receive a single shot sciatic nerve block to serve as the primary anesthetic and as part of a multi-modal post-operative analgesic plan.
- Trial name
- NCT01616173
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Cholecystectomy, Postoperative Pain
Analgesic Effect of Quadratus Lumborum Block Application After Laparoscopic Cholecystectomy Surgery
Laparoscopy is frequently used today for intraabdominal operations. Laparoscopic procedure has become the treatment of choice for many patients with symptomatic cholelithiasis.
- Conditions
- Cholecystectomy, Postoperative Pain, Nerve Block
- Trial name
- NCT03308955
- Testing
- Tramadol, Ultrasound guided Quadratus Lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Transcranial Direct Current Stimulation, Dysmenorrhea Primary
Physical Performance and Analgesic Effects of tDCS in Primary Dysmenorrhea
Technological advances and non-invasive techniques to modulate brain function have been developed, including transcranial Direct Current Stimulation (tDCS).
- Conditions
- Transcranial Direct Current Stimulation, Dysmenorrhea Primary, Pain, Mental Disorders
- Trial name
- NCT03184740
- Testing
- Active Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Osteoarthritis, Hip, Osteoarthritis, Knee
A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee
The study schedule consists of a Screening Period (up to 14 days), a blinded 4- week Titration-to-Effect Period with weekly visits, a blinded 4-week Maintenance Treatment Period at the optimal dose level determined for each…
- Conditions
- Osteoarthritis, Hip, Osteoarthritis, Knee, Arthritis, Joint Diseases
- Trial name
- NCT02944448
- Testing
- CR845 tablet 1 mg, CR845 tablet 2.5 mg, CR845 tablet 5 mg
- Where
- 35 sites in United States
- Volunteers
- 761 people
- Sponsor
- Cara Therapeutics, Inc.
Analgesic Effect
Comparison of Caudal Blockade and Dorsal Penile Nerve Block With and Without the Intravenous Administration of Dexamethasone for Analgesia After Paediatric Male Circumcision
Male infant circumcision is a frequently performed, but painful procedure. A variety of methods, both systemic and locoregional, have been developed to overcome postoperative pain after circumcision.
- Trial name
- NCT05598255
- Testing
- Dexamethasone, Caudale Blockade with levobupivacaine, Dorsal penile nerve block with levobupivacaine
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Lumbar Fixation Surgery
Evaluation Of Three Different Anagesic Techniques In Patients Undergoing Lumbar Fixation Surgery
Lumbar spinal stenosis is a degenerative condition characterized by the narrowing of the space surrounding the neurovascular structures of the lumbar vertebrae, resulting from age-related changes in the intervertebral discs…
- Trial name
- NCT06801574
- Testing
- Erector Spinae Plane Block, infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Ataturk University
Arthroscopy
Effect of Celecoxib Versus Placebo Before and After Knee Surgery on Overall Use of Analgesics After Surgery
To compare total analgesic use at 24 hours after arthroscopic knee surgery in celecoxib-treated versus placebo-treated patients
- Trial name
- NCT00633438
- Testing
- Celecoxib
- Where
- 18 sites in United States
- Volunteers
- 204 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
General Anesthetic Drug Adverse Reaction
Effect of Tegileridine Versus Sufentanil as Analgesic Components on Opioid-Induced Cough During Anesthesia Induction
In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine.
- Trial name
- NCT07323043
- Testing
- Tegilerdine, Sufentanil
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang