Clinical trials: Analgesic Effect
Hip Fractures
Analgesic Effect of Fascia Iliaca Compartment Block in Geriatric Patients With Hip Fracture
As population in Hong Kong is aging, incidence of geriatrics hip fractures rises. Operative treatment for selective patients offers pain control, early mobilization and reduction in medical morbidities and mortalities.
- Trial name
- NCT04478552
- Testing
- Fascia iliaca compartment block
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- United Christian Hospital
Idiopathic Scoliosis, Erector Spinae Plane Block
Erector Spinae Plane Block v.s Patient Controlled Analgesia in Correction Surgery for Idiopathic Scoliosis
Scoliosis correction surgery involves extensive surgical wounds, intense intraoperative stimulation, and severe postoperative pain, often necessitating the use of potent opioids.
- Conditions
- Idiopathic Scoliosis, Erector Spinae Plane Block, Patient Controlled Analgesia
- Trial name
- NCT06728046
- Testing
- ESPB, PCA
- Where
- China
- Volunteers
- 40 people
- Sponsor
- West China Hospital
Chronic Pain
Real-World Registry Study on Clinical Analgesic Effect of Acetylaconitine Tablets
1. To observe the clinical analgesic effect, safety and adverse reactions of acetylaconitine. 2. To study and analyze the main influencing factors of the acetylaconitine tablets.
- Trial name
- NCT05687929
- Where
- China
- Volunteers
- 3,500 people
- Sponsor
- Ke Ma
Pain, Postoperative
Effects of Intra-Operative Ropivaciane Epidural Injection on Post-Operative Outcomes Following Elective Lumbar Fusion
The following is a double blinded, randomized controlled clinical trial to test the hypothesis that a single epidural injection of Ropivaciane® intra operatively will:1) Single intra-operative epidural injection of Ropivaciane®…
- Trial name
- NCT03035656
- Testing
- Ropivacaine, Saline
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Horizon Health Network
Thoracic Sympathectomy
Analgesic Effect of Erector Spinae Versus Serratus Anterior Plane Block for Thoracoscopic Sympathectomy
Thoracic incisions are painful and associated with chronic post-surgical pain and inadequate analgesia is associated with poorer postoperative outcomes.
- Trial name
- NCT04486014
- Testing
- Erector spinae plane block, Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Pain, Postoperative
Ultrasound Guided Posterior Versus Lateral Transversus Abdominis Plan Block for Prolonged Postoperative Analgesic Effect in Children
Ultrasound Guided Posterior Versus Lateral Transversus Abdominis Plan Block for Prolonged Postoperative Analgesic Effect in Children
- Trial name
- NCT04049838
- Testing
- postoperative analgesia for lower abdominal surgery in children
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Kasr El Aini Hospital
Abdominal Cancer
Cardio-pulmonary and Analgesic Effects of Pre-peritoneal VS Epidural Infusion of L-bupivacaine on Abd. Cancer Patients
60 Patients will be randomly assigned using computer generated randomization program (http://www.randomizer.org) into two groups, First group (Control group ,Group of continous epidural infusion [CEI]), where patients will…
- Trial name
- NCT04152564
- Testing
- levo-bupivacaine infusion via Thoracic epidural catheter, levo-bupivacaine infusion via preperitoneal catheter
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Postoperative Acute Pain, Chronic Pain
Comparison of Postoperative Analgesic Efficacy of Interscalene and Suprascapular Blocks Used in Arthroscopic Shoulder Surgery
The Importance of Postoperative Analgesia in Shoulder Surgery Shoulder surgery is an orthopedic procedure that can be performed either through open surgery or arthroscopically.
- Trial name
- NCT07483814
- Testing
- rescue analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor, Analgesia
Postoperative Analgesic Effect of Esketamine
The aim of this study was to determine whether the addition of esketamine to morphine would improve postoperative analgesia after caesarean section.
- Trial name
- NCT05582135
- Testing
- 2 mg morphine sulfate, 0.25mg/kg esketamine, 0.25mg/kg of esketamine in combination with 2 mg morphine sulfate
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Xuanhan County People's Hospital
Postoperative Pain
Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy Surgery
The primary purpose of this study is to determine if CR845 is effective in treating the pain associated with a laparoscopic hysterectomy.
- Trial name
- NCT01361568
- Testing
- CR845
- Where
- 18 sites in United States
- Volunteers
- 203 people
- Sponsor
- Cara Therapeutics, Inc.
Herpes Zoster, Neuralgia
NGX-4010 for the Treatment of Postherpetic Neuralgia
The purpose of the study is determine if an investigational drug, NGX-4010 (high-concentration capsaicin dermal patches) is effective in treating pain associated with post-herpetic neuralgia (PHN).
- Conditions
- Herpes Zoster, Neuralgia, Pain, Peripheral Nervous System Diseases
- Trial name
- NCT00061776
- Testing
- Capsaicin Dermal Patch
- Where
- 28 sites in United States
- Volunteers
- 300 people
- Sponsor
- NeurogesX
Recurrent Tonsillitis, Obstructive Sleep Apnea
Post-operative Pain Control After Pediatric Adenotonsillectomy
Adenotonsillectomy is one of the most common surgical procedures performed in the pediatric population in the United States. It is generally a well-tolerated procedure with post-operative bleeding risk ranging from 3-5% in…
- Conditions
- Recurrent Tonsillitis, Obstructive Sleep Apnea, Sleep Disordered Breathing, Adverse Reaction to Drug
- Trial name
- NCT02296840
- Testing
- Ibuprofen, Hydrocodone-Acetaminophen
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Emory University
Inguinal Hernia, Postoperative Pain
Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair
A multicenter, single-dose study in children 12 to <17 years of age, 6 to <12 years of age, and 2 to <6 years of age who are scheduled for elective open inguinal hernia repair.
- Trial name
- NCT03262688
- Testing
- Bupivacaine HCl collagen-matrix implant, Bupivacaine HCl infiltration
- Where
- 11 sites in United States
- Volunteers
- 159 people
- Sponsor
- Innocoll
Pain
Efficacy of Lumiracoxib in Relieving Moderate to Severe Post-dental Surgery Pain, Compared to Both Placebo and Celecoxib
This study will assess the safety and efficacy of lumiracoxib 400 mg in relieving moderate to severe post-dental surgery pain, compared to both placebo and celecoxib 400 mg.
- Trial name
- NCT00348491
- Testing
- Lumiracoxib
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- Novartis Pharmaceuticals
Gonarthrosis
Role of Femoral Nerve Block on Prevention of Postoperative Deep Venous Thromboembolism
To investigate whether preemptive analgesic of femoral nerve block could prevent deep venous thromboembolism due to inhibiting the excessive release of neutrophil elastase and inflammatory cytokines.
- Trial name
- NCT02411097
- Testing
- femoral nerve block
- Where
- China
- Volunteers
- 120 people
- Sponsor
- General Hospital of Ningxia Medical University
Chronic Pain
Observational Study of the Analgesic Effect of Treatment With rTMS in Patients With Chronic Neuropathic Pain
For ten years, rTMS, repetitive transcranial magnetic stimulation of the motor cortex, has found its place in the treatment of drug-resistant neuropathic pain.
- Trial name
- rTMSDOULNEURO (NCT02506699)
- Testing
- analgesic effect of rTMS
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Postoperative Pain, Acute
Analgesic and Anti-inflamatory Effect of Vit. B
Vitamin C, also known as ascorbic acid, is a potent reducing agent and antioxidant that plays a crucial role in various metabolic processes.Vitamin B complex, a group of eight essential B vitamins, plays a crucial role in…
- Trial name
- vit B/vit C (NCT06857734)
- Testing
- Vitamin B Complex, vitamin C
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Benha University
Total Knee Arthoplasty, Knee Pain
TENS in Post-operative Total Knee Arthroplasty Recovery and Intra-venous Analgesics Requirement
Total knee arthroplasty (TKA) is among the major advancements for the treatment of knee pain and improvement of physical function when conservative management fails to comply with.
- Trial name
- NCT05470244
- Testing
- Routine Physical Therapy and Intra-venous analgesic regimen, Transcutaneous Electrical Nerve Stimulation along with Routine Physical Therapy and Intra-venous analgesic regimen
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Effect of Drug
Efficacy of Trypsin-Chymotrypsin On Post-operative Pain After Single Visit Root Canal Treatment
Achieving effective pain control after endodontic treatment is still a disruptive event to all the clinicians. There is a knowledge gap regarding the effect of protease on postoperative pain following root canal treatment…
- Trial name
- NCT05479747
- Testing
- post operative analgesics
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Lung Cancer
Bupivacaine Liposome Serrate Anterior Plane Block vs Traditional Thoracic Paravertebral Block
In this study, patients will receive bupivacaine liposome serratus anterior plane block or ropivacaine paraspinal block to manage postoperative pain.
- Trial name
- NCT06135545
- Testing
- Bupivacaine Liposome SAPB, Traditional TPVB
- Where
- China
- Sponsor
- Shiyou Wei