Clinical trials: Analgesic Effect
Post Operative Pain, Acute
Comparison Between the Analgesic Effect of Fascia Transversalis Block vs Caudal Block
Despite the growing interest in interfascial blocks and their successful use in pediatric surgeries, no previous randomized clinical trials have directly compared the analgesic efficacy, opioid-sparing effect, and safety profile…
- Trial name
- NCT07235475
- Testing
- Caudal Block Anesthesia, Fascia Transversalis Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Periapical Diseases
Effect of Aloe Vera Gel as an Intra Canal Medicament
This research will overview the effect of aloe vera gel (AVG) as intra canal medicament in patients with asymptomatic periapical lesions.
- Trial name
- NCT06243601
- Testing
- Aloe vera Gel
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Islamabad Medical and Dental College
Anesthesia, Local
Analgesic Effect of Illiohypogastic & Ilioinguinal Nerve Block in TAVR - TF (Prospective Randomized Study)
The purpose of the study is to compare the effect of illiohypogastric and ilioinguinal nerve block with the local infiltration with lidocaine in patients undergoing TAVI
- Trial name
- NCT06362915
- Testing
- Lidocaine, Bupivacain
- Where
- 2 sites in Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Lumbar Spinal Fusions
Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Acute pain management is challenging in patients after spinal fusions, particularly since most have taken analgesics for prolonged periods before choosing the surgical alternative.
- Trial name
- NCT01366196
- Testing
- Pregabalin 150 mg
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Hospital for Special Surgery, New York
Proctalgia
Analgesic Effect of an Injection of Botulinum Toxin Type A in the Ganglion Impar in Patients With Chronic Proctalgia
The main objective is to evaluate the analgesic efficacy of botulinum toxin type A in refractory chronic proctalgia one month after a bilateral injection of 50 units of Botox ® in the ganglion Impar (total dose = 100 units)
- Trial name
- Impartox (NCT01331356)
- Testing
- Botox
- Where
- 2 sites in France
- Volunteers
- 18 people
- Sponsor
- Nantes University Hospital
Opioid Use, Postoperative Pain
Analgesic Effects of Intrathecal Morphine and Bilateral Erector Spina Plane Block in Elective Cesarean Section
Cesarean section cause severe pain due to surgical incision, abdominal wall retraction and visceral organ movements. Cesarean section can be performed with general anesthesia, spinal anesthesia, epidural anesthesia and combined…
- Trial name
- NCT05698927
- Testing
- Erector Spinae Plane Block (bilaterally, via 20ml % 0.25 bupivacain) and Intrathecal Morphine (100 mcg)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Marmara University
Dexmedetomidine Analgesia, Knee Surgery
Intravenous Regional Analgesia of Dexmedetomidine
Dexmedetomidine is a highly selective α₂-adrenergic receptor agonist that exerts its effects by inhibiting the release of norepinephrine at presynaptic nerve terminals, leading to reduced sympathetic activity; This mechanism…
- Trial name
- Dexmedetomidin (NCT07131579)
- Testing
- Normal Saline, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Analgesia, Postoperative
Comparison Between Fentanyl and Dexmedetomidine As Adjuvant to Bupivacaine in Combined IPACK and Adductor Canal Block for Postoperative Analgesia After Knee Surgeries
This study will be undertaken to compare the analgesic effects of of fentanyl versus dexmedetomidine as adjuvant to bupivacaine in combined IPACK and ACB for pain management after total knee arthroplasty.
- Trial name
- NCT06759116
- Testing
- Control group, Fentanyl group, Dexmedetomidine group
- Where
- Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Back Pain Lower Back Chronic
Caudal Epidural Injection of Dextrose For Low Back Pain
Objective: The purposes of the study are to 1. Explore the immediate and short term (to 48 hour) analgesic potential of epidural D5W in comparison to normal saline. 2.
- Trial name
- NCT01547364
- Testing
- Saline, Dextrose
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Smigel, Liza, M.D.
Post Operative Pain
Analgesic Effect of M-TAPA on LC
Objective: To investigate the postoperative analgesic efficacy of M-TAPA block and its effect on opioid consumption in patients undergoing laparoscopic cholecystectomy (LC) surgery.
- Trial name
- NCT05891652
- Testing
- modified thoracoabdominal nerve block through perichondrial approach
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Cumhuriyet University
Effect of Protocolized Sedation on Days of Mechanical Ventilation in the ICU
Evaluation of an Analgosedation Protocol in Mechanically Ventilated Patients
The purpose of this study is to evaluate how the investigators provide sedation (medicine that make you sleepy) in the investigators intensive care unit (ICU).
- Trial name
- NCT02100735
- Testing
- Sedation protocol
- Where
- United States
- Sponsor
- Tampa General Hospital
Pain, Quality of Life
Evaluation of the Effects of Different Analgesics on Pericoronitis Pain and Quality of Life
Pericoronitis is a painful inflammatory condition which is well known for its negative impact on quality of life of those affected.
- Trial name
- NCT03745599
- Testing
- Diclofenac, Flurbiprofen, Benzydamine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Near East University, Turkey
Surgical Procedure, Unspecified
TFPB vs QLB III in Infra-umbilical Pediatric Surgeries
Regional anesthetic techniques; they reduce postoperative morbidity, provide early mobilization and provide great advantages by significantly reducing the need for narcotic analgesics.
- Trial name
- NCT05671484
- Testing
- Transversalis Fascial Plane Block, Quadratus Lumborum Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Namik Kemal University
Anesthesia
Bispectral Index (BIS) Monitoring in Abdominal Surgery
Bispectral Index Monitoring (BIS) has been proven to be effective in preventing awareness. Optimizing anesthesia level using BIS monitoring, neither to light nor to deep will probably help to shorten recovery time and reduce drug…
- Trial name
- NCT01470898
- Testing
- bispectral index monitoring
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital Dubrava
Acute Pain
Analgesic Effect of Liposomal Bupivacaine
Brachial plexus blocks (BPB) are commonly used to provide regional anaesthesia for patients undergoing distal radial fracture surgery.
- Trial name
- NCT05118399
- Testing
- Bupivacaine Injection [Marcaine], Bupivacaine Liposome 13.3 MG/ML [Exparel]
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- The University of Hong Kong
Transversalis Fascia Plane Block
Adding Calcitonin to Bupivacaine in Transversalis Fascia Plane Block for Cesarean Section
Evaluate calcitonin as an adjuvant to bupivacaine in ultrasound guided tansversalis fascia plane block
- Trial name
- NCT07033104
- Testing
- us guided Transversalis fascia plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Neuropathic Pain
Paracetamol and Neuropathic Pain
The aim of this study is to evaluate the analgesic effect of paracetamol in patients suffering from pain with a peripheral neuropathic component in the presence of their usual treatment.
- Trial name
- PAeoNy (NCT03559985)
- Testing
- paracetamol
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neuropathic Pain
Lidocaine and Neuroma Pain Related Modalities
Background Subanesthetics concentrations of lidocaine are able to produce a differential block of the ectopic discharges, but not propagation of impulses, suppressing differentially the associated neuropathic pain symptoms.
- Trial name
- NCT02300038
- Testing
- Lidocaine (Xylocaine), NaCl
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Pain, Postoperative, Disability Physical
Effects of Interpectoral-Pectoserratus Plane Block After Breast Cancer Surgery
The aim of this study: It was aimed to observe the effects of intraoperative and preoperative PECS II block on postoperative pain, amount of analgesic use and shoulder joint range of motion in patients who underwent breast cancer…
- Conditions
- Pain, Postoperative, Disability Physical, Quality of Life
- Trial name
- NCT05568589
- Testing
- Preoperative Interpectoral - Pectoserratus Plane Block, Intraoperative Interpectoral - Pectoserratus Plane Block, Non Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Bakircay University
Analgesia, Postoperative Pain
Ultrasound-Guided Serratus Anterior Plane Block in Pneumothorax Surgery
A prospective randomized controlled study was undertaken to compare the postoperative analgesic effect between ultrasound-guided serratus anterior plane block and intercostal nerve block after single port video-assisted…
- Conditions
- Analgesia, Postoperative Pain, Pneumothorax
- Trial name
- NCT04191850
- Testing
- Single Port Video-Assisted Thoracoscopic Surgery
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Kyungpook National University Hospital