Clinical trials: Analgesic Effect
Pain
Analgesic Effect of Oral Glucose in Neonates
Background: Male circumcision is one of the oldest and most common operations performed all over the world. It can be performed at different ages, using different surgical techniques, for different religious, cultural and medical…
- Trial name
- NCT04467177
- Testing
- 30% glucose
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Chronic Pain
The Effect of Binaural Beats on Pain Perception and Analgesic Medication Use in Patients Suffering From Chronic Pain
This study evaluates the effect of binaural beats on pain perception and subsequent need for analgesic medication use in patients suffering from diseases causing chronic pain.
- Trial name
- NCT03160300
- Testing
- Music with Binaural Beats, Music
- Where
- Greece
- Volunteers
- 21 people
- Sponsor
- Aristotle University Of Thessaloniki
Sedative Adverse Reaction, Analgesic Adverse Reaction
The Use of Midazolam and Remifentanil During Dialysis Access Procedures
BACKGROUND: Sedation and analgesia are related to unexpected adverse events in chronic renal failure patients undergoing arteriovenous fistula placement procedures under monitored anesthesia care (MAC).
- Conditions
- Sedative Adverse Reaction, Analgesic Adverse Reaction, Midazolam Adverse Reaction, Adverse Reaction to Drug
- Trial name
- NCT04226443
- Testing
- Midazolam intravenous injection, Remifentanil intravenous bolus dose
- Volunteers
- 99 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Pain, Postoperative, Disability Physical
Effects of Interpectoral-Pectoserratus Plane Block After Breast Cancer Surgery
The aim of this study: It was aimed to observe the effects of intraoperative and preoperative PECS II block on postoperative pain, amount of analgesic use and shoulder joint range of motion in patients who underwent breast cancer…
- Conditions
- Pain, Postoperative, Disability Physical, Quality of Life
- Trial name
- NCT05568589
- Testing
- Preoperative Interpectoral - Pectoserratus Plane Block, Intraoperative Interpectoral - Pectoserratus Plane Block, Non Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Bakircay University
Postoperative Pain
Morphine Added to Ropivacaine for FICB for Postoperative Analgesia
prospective, randomized double blinded study to investigate the effects of morphine as an adjuvant to ropivacaine on FICB
- Trial name
- NCT03875274
- Testing
- Ropivacaine, Morphine, Ropivacaine, Saline
- Where
- Nepal
- Volunteers
- 70 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Analgesics, Opioid, Anesthetics, Local
Opioid Use of Local Anaesthetic Agents in Open Heart Surgery and Its Effect on Recovery
The aim of this randomized controlled study was to investigate the effect of injecting local anesthetic agents into the sternotomy incision site and around the drains on the amount of opioids used in the postoperative period and…
- Trial name
- NCT06642077
- Testing
- LIDOFAST 40 mg/2 ml + 0.025 mg/2 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Open Gastrectomy With Gastric Cancer
Comparison of Analgesic Effects According to Patient-controlled Epidural Analgesia Modes in Patients Undergoing Open Gastrectomy
Epidural PCA (patient controlled analgesia) for post-operative pain management are effective analgesic method. It is widely used in the postoperative pain management for decades.
- Trial name
- NCT03430440
- Testing
- Apply CIPKA mode, Conventional mode
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Yonsei University
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Fibromyalgia
Analgesic Effect of Music Listening During Pain Elicitation in Fibromyalgia
Patients with fibromyalgia (FM) are more sensitive to things that cause pain. Music lowers self-reported pain in patients with chronic pain.
- Trial name
- FMMusic (NCT04059042)
- Testing
- Music Listening
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Kansas Medical Center
Analgesia, Postoperative
Comparison Between Fentanyl and Dexmedetomidine As Adjuvant to Bupivacaine in Combined IPACK and Adductor Canal Block for Postoperative Analgesia After Knee Surgeries
This study will be undertaken to compare the analgesic effects of of fentanyl versus dexmedetomidine as adjuvant to bupivacaine in combined IPACK and ACB for pain management after total knee arthroplasty.
- Trial name
- NCT06759116
- Testing
- Control group, Fentanyl group, Dexmedetomidine group
- Where
- Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain, Nephrectomy
ESP Block vs. EXORA Block for Postoperative Pain in Nephrectomy
The goal of this observational study is to learn about the effects of two pain control techniques used after laparoscopic nephrectomy (kidney removal surgery) in adults.
- Trial name
- NCT07640282
- Testing
- Erector Spinae Plane Block, External Oblique Rectus Abdominis Block
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Analgesics
A Safety Trial to Compare Different Analgesics in Combination With Low Dose Aspirin to Study Their Bleeding Properties and Their Effects on the Stomach
The purpose of this study is to compare several analgesics given in approved daily doses in combination with a daily cardioprotective dose of aspirin (81 mg), to study their bleeding properties and their effects on the stomach in…
- Trial name
- NCT00261586
- Testing
- aspirin, acetaminophen, ibuprofen, naproxen, celecoxib, rofecoxib
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Shoulder Surgery
Effect of Interscalene and Suprascapular Nerve Block on Analgesia Consumption After Adhesive Capsulitis Surgery
In this study, a combination of different types of blocks for adhesive capsulitis surgery, the investigators will investigate the impact on patient satisfaction and analgesic consumption after surgery.
- Trial name
- NCT04769570
- Testing
- interscalene brachial plexus block, suprascapular nerve block, Group Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Intensive Care Unit Syndrome, Mechanical Ventilation Complication
Ketamine Infusion as Sedative Analgesic in Severe ARDS
To evaluate whether ketamine is a safe sedative-analgesic agent to be used in an intensive care unit (ICU) setting as compared to traditionally used agents such as propofol, opioids, and midazolam
- Conditions
- Intensive Care Unit Syndrome, Mechanical Ventilation Complication, Sedatives and Hypnotics Causing Adverse Effects in Therapeutic Use, Delirium
- Trial name
- KISS (NCT04818827)
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Interfaith Medical Center
HİP FRACTURE, Hip Surgery (Lateral Incision)
Perioperative Analgesic Effects of PENG Versus PENG Plus LFCN Block in Hip Surgeries
This study is designed to find the best way to control pain after hip surgery performed through a side (lateral) incision. Two different types of nerve blocks used before the operation will be compared.
- Conditions
- HİP FRACTURE, Hip Surgery (Lateral Incision), Postoperative Pain Management, Analgesia, Postoperative
- Trial name
- NCT07329829
- Testing
- Pericapsular nerve group (PENG) block, Lateral Femoral Cutaneous Nerve (LFCN) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Analgesia
Analgesic Requirements for Lumbar Fixation With General Anaesthesia Versus Continuous Caudal Epidural
In this clinical study, the investigators will justify the current practice of combined continuous caudal epidural with general anaesthesia in adult patients undergoing lumbar fixation versus general anaesthesia.
- Trial name
- NCT06929611
- Testing
- Combined continous caudal epidural with general anaesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Lower Abdominal Surgery
Comparison Between the Quadratus Lumborum Block ,Erector Spinae Plane Block in Lower Abdominal Surgery
the purpose of study is comparison between the analgesic effect of two techniques in adult lower abdominal surgeries
- Trial name
- NCT05524038
- Testing
- Bupivacaine Hydrochloride, Ultrasound device, Dexamethasone
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Fayoum University Hospital
Pain
Analgesic Effect of Ropivacaine Plus Fentanyl vs Ropivacaine for Continuous 3-in-1 FNB After Total Knee Arthroplasty
The postoperative analgesic effect of the continuous 3-in-1 femoral nerve block (FNB) with ropivacaine/fentanyl or with ropivacaine were compared in total knee arthroplasty.
- Trial name
- NCT02501863
- Testing
- Femoral nerve block with ropivacaine+fentanyl, Femoral nerve block with ropivacaine
- Volunteers
- 40 people
- Sponsor
- National Medical Center, Seoul
Hand Injuries
Analgesic Effects of Gabapentin and Paracetamol
This research is about the effects of drug gabapentin; which is an amino acid that is structurally similar to neurotransmitter GABA.
- Trial name
- GABA (NCT04068506)
- Testing
- Gabapentin 600 mg Tab
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Dow University of Health Sciences
Mammary Cancer, Serratus Anterior Plane Block
Serratus Anterior Plane Block for Modified Radical Mastectomy: Double-point VS Single-point
Nowadays, the incidence of breast cancer is the first number of malignant tumors, and the primary treatment method is surgery. As is known to all, less postoperative complications and enhanced recovery are closely related to…
- Conditions
- Mammary Cancer, Serratus Anterior Plane Block, Postoperative Pain
- Trial name
- NCT05299021
- Testing
- Double-point SAPB, Single-point SAPB
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Fudan University