Clinical trials: Analgesic Medication
Chronic Pain
Effect of Wearable Health Technology on Patients Treated for Chronic Pain at Geisinger Health System
This is a proof of concept study to measure the effect of Wearable Health Technology (WHT), including the Apple Watch, iPhone, Pain App and Provider Dashboards on important clinical outcomes in patients treated for chronic pain.
- Trial name
- NCT03299556
- Testing
- WHT
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Purdue Pharma LP
Pain, Acute
The Efficacy of Acu-TENS as an Adjunct Analgesic During USG-MVA
Objectives: To prospectively evaluate the potential of acu-TENS to reduce the pain experienced by women undergoing ultrasound-guided manual vacuum aspiration (USG-MVA) and evaluate its safety profile.
- Trial name
- NCT06411054
- Testing
- Acu-TENS
- Where
- Hong Kong
- Volunteers
- 108 people
- Sponsor
- Chinese University of Hong Kong
Cancer Pain, Analgesic Drugs
Adequacy of Pain Treatment in Radiotherapy
Aim of the study is to evaluate adequacy of pain treatment in oncologic patients, accessing to Radiotherapy Unit
- Trial name
- NCT03550599
- Testing
- Patients accessing to Radiotherapy Unit
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
PTSD, Psychiatric Illness
Killing Pain - Use of Analgesic, Sedative and Anxiolytic Medication and the Development of Psychiatric Illness in Adolescents
Prescription of analgesic, sedative, and anxiolytic medication for children and adolescents is increasing in Western countries. In recent decades, rates have also increased in Norway, despite a relatively restrictive prescription…
- Conditions
- PTSD, Psychiatric Illness, Prescription Drug Dependence, Addiction
- Trial name
- NCT04336605
- Testing
- Age & Development, Socioeconomy, Traumatic Events
- Where
- Norway
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Pain, Postoperative
Efficacy of Transversus Abdominis Plane Block Versus Local Injection of Pain Medication
The purpose of this study is to determine if there is a better method of administering pain medication prior to minimally invasive gynecological surgery so that postoperative pain and/or narcotic usage may be minimized.
- Trial name
- NCT02314104
- Testing
- ropivacaine
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Liberman, Eric, D.O.
Pain
Metamizol for the Treatment of Neoplastic Chronic Pain
Study to evaluate the efficacy of metamizole in reducing morphine requirements in patients with moderate to severe chronic cancer pain in comparison to administration of placebo or diclofenac.
- Trial name
- NCT02181920
- Testing
- Metamizole, Diclofenac
- Volunteers
- 6 people
- Sponsor
- Boehringer Ingelheim
Opioid Dependence
Safety and Efficacy of Probuphine in the Treatment of Opioid Dependence
Buprenorphine (BPN) is an approved treatment for opioid dependence, however, in taking oral tablets, patients experience withdrawal and cravings when the variable BPN levels in the blood are low.
- Trial name
- NCT00447564
- Testing
- Probuphine
- Where
- 18 sites in United States
- Volunteers
- 163 people
- Sponsor
- Titan Pharmaceuticals
Postoperative Pain
Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy Surgery
The primary purpose of this study is to determine if CR845 is effective in treating the pain associated with a laparoscopic hysterectomy.
- Trial name
- NCT01361568
- Testing
- CR845
- Where
- 18 sites in United States
- Volunteers
- 203 people
- Sponsor
- Cara Therapeutics, Inc.
Post Tonsillectomy Pain
The Effect of Pre Surgery Dog Visits on Post Surgery Consumption of Pain Medication
The objective of this study is to examine the effects of pre surgery dog visits as compared to a costumed character or parents-only on the consumption of pain medication after surgery.
- Trial name
- Dog (NCT00452738)
- Testing
- Therapy dog, Costumed character, Parents-only
- Where
- United States
- Sponsor
- Oklahoma State University Center for Health Sciences
Tooth Extraction Status Nos, Post Operative Pain
A Mobile Application for Post-op Analgesic Consumption
Surgical extraction of third molars is one of the most common outpatient procedures performed by oral surgeons. The prescription of postoperative narcotic and NSAID analgesics is the standard of care practice to relieve symptoms…
- Conditions
- Tooth Extraction Status Nos, Post Operative Pain, Patient Satisfaction, Narcotic Use
- Trial name
- NCT03197311
- Testing
- Mobile app
- Where
- United States
- Sponsor
- Boston University
Depression, Unipolar
Repeated Neurocognitive Measurements in Depressed Patients
In this project, we will A) track the functioning of a collection of potential neurobiological targets for depression over time, B) examine how fluctuations in the functioning of those targets relates to real-world functioning…
- Trial name
- NCT05991232
- Testing
- Intravenous Ketamine
- Where
- United States
- Sponsor
- Jay Fournier
Multimodal Analgesia, Nonsteroidal Anti-inflammatory Drugs
NSAID vs. Narcotics
This will be a single-center, prospective observational study. The study will compare post-operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and Percocet…
- Trial name
- NCT02915055
- Testing
- Ibuprofen 600 mg, standard oxycodone/acetaminophen
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Chronic Severe Pain
A Non-interventional, Observational Study for Targinact® Treatment in Patients With Chronic Severe Pain
This non-interventional, observational study is set up on request of the Belgian reimbursement authorities and evaluates the efficacy of Targinact with regard to pain relief and constipation in daily clinical practice in Belgium…
- Trial name
- NCT01710904
- Testing
- Targinact® (oxycodone/naloxone)
- Where
- Belgium
- Volunteers
- 68 people
- Sponsor
- Mundipharma CVA
Opioid Withdrawal
Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal
This Phase 1b/2 inpatient study assessed the safety, pharmacokinetics, and early signs of efficacy of escalating doses of BXCL501 versus placebo following discontinuation of morphine maintenance.
- Trial name
- NCT04470050
- Testing
- Dexmedetomidine
- Where
- 3 sites in United States
- Volunteers
- 225 people
- Sponsor
- BioXcel Therapeutics Inc
Gallbladder Diseases
Sugammadex on Remifentanil Ce for Preventing Emergence Cough in Female
The purpose of this study is to investigate the optimal Ce of remifentanil for preventing emergence cough following extubation during general anesthesia in female who are reversed with sugammadex or neostigmine.
- Trial name
- NCT04407078
- Testing
- Sugammadex Injectable Product, Neostigmine Injectable Product
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ajou University School of Medicine
Opioid Use
Self-reported Usage Patterns of Opioid Analgesic Medications After Surgery
The primary objective of this study is to better understand post-discharge utilization of prescribed opioid analgesic medications following surgery.
- Trial name
- NCT03034278
- Testing
- Not applicable - no intervention
- Where
- United States
- Volunteers
- 785 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
HIV Infections
Pilot Study of High-Concentration Capsaicin Patches in the Treatment of Painful HIV-Associated Neuropathy
The purpose of the study is to gain initial information on the tolerability and feasibility of high-concentration capsaicin patches for the treatment of painful HIV-associated neuropathy, whether resulting from HIV disease and/or…
- Trial name
- NCT00061152
- Testing
- Capsaicin Dermal Patch
- Where
- 3 sites in United States
- Sponsor
- NeurogesX
Virtual Reality Therapy
Modifying Virtual Reality Analgesia With Low-Dose Pain Medication
The purpose of this study is to determine how pain relief is modified when the investigators combine the Virtual Reality based Snow World game with certain pain medications.
- Trial name
- NCT01840774
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Washington
Addiction
Primary Dependence to Analgesic Drugs
Abuse of analgesics represents an important part of prescription drug abuse. The consequences in terms of morbidity and mortality at the population level could reach worryingly high levels, as illustrated by the US context.
- Trial name
- NEO-ADDICT (NCT03684317)
- Where
- France
- Sponsor
- University Hospital, Toulouse
Myofascial Trigger Point Pain, Myofacial Pain
Trigger Point Injections Versus Lidocaine Patch for Myofascial Pain in the Emergency Department
The aim of this trial is to investigate the efficacy of trigger point injections with 1% lidocaine in reducing myofascial back and neck pain in the Emergency Department compared to lidocaine patches 5%.
- Trial name
- NCT05151510
- Testing
- Trigger point injection with 1% lidocaine, Lidocaine patch 5%
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine