Clinical trials: Anastomosis, Leaking
Esophageal Anastomotic Leak, Tissue Pressure of Oxygen
Ischemic Conditioning of the Gastric Conduit in Esophageal Cancer.
This study is a randomized clinical trial to clarify if preoperative embolization of gastric arteries can reduce the incidence of oesophagogastric leakage after an esophagectomy for esophageal cancer comparing an experimental…
- Trial name
- NCT04268654
- Testing
- Preoperative Arterial Embolization
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Treatment, Anastomotic Leakage
TreatmENT of AnastomotiC LeakagE After COLON Cancer Resection
This international multicentre retrospective cohort study aims to research anastomotic leakage after colon cancer resection and has two main objectives: 1.
- Conditions
- Treatment, Anastomotic Leakage, Resection, Colon Cancer
- Trial name
- TENTACLE-Colon (NCT06528054)
- Testing
- Development of a model for predicting 90-day mortality and to compare various treatment strategies for anastomotic leakage
- Volunteers
- 2,000 people
- Sponsor
- Radboud University Medical Center
Anastomotic Leakage
The Relationship Between Drainage Fluid and Anastomotic Leakage After Colorectal Cancer Surgery
A prospective and analytical study on the detection of early anastomotic leakage by abdominal drainage fluid after colorectal cancer surgery. pay attention to indicators including bilirubin
- Trial name
- NCT05191602
- Testing
- drainge fluid
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Southwest Hospital, China
Rectal Disease, Sigmoid Disease
Evaluation of Intestinal Vascolarization With Indocianine Green Angiography During Rectal Resection or Left Colectomy
A randomized controlled multicenter trial on the usefulness of intraoperative angiography with indocyanine green to assess anastomosis perfusion in patients who undergo laparoscopic rectal resection or left colectomy.
- Trial name
- NCT02662946
- Testing
- ICG- angiography, No angiography
- Where
- Italy
- Volunteers
- 208 people
- Sponsor
- Scientific Institute San Raffaele
Anastomotic Leak Large Intestine, Right Colon Tumors
Anastomotic Leakage After Right Hemicolectomy for Cancer, a Prospective Multicenter Study of SICO-CC Network
This is a nationwide prospective observational study to assess the overall clinical anastomotic leakage rate after right hemicolectomy for cancer, to detect the independent risk factors for AL, and to develop a clinical…
- Trial name
- ALRIGHT (NCT06688383)
- Where
- Italy
- Volunteers
- 1,839 people
- Sponsor
- San Luigi Gonzaga Hospital
Body Weight, Post-Op Complication
Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)
This Study aims to develop machine learning models with the ability to predict patients' BMI and complications after Bariatric Surgery (CABS-Score).
- Conditions
- Body Weight, Post-Op Complication, Anastomosis, Leaking, Hiatal Hernia
- Trial name
- NCT05710913
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Dr. Med Anas Taha
Esophageal Malignant Neoplasm Primary, Anastomotic Leak
Registry Study of People Who Are Having an Esophagectomy and Are at High Risk of Anastomotic Leak
The main purpose of this study is to look at how often anastomotic leaks happen in participants who are at high risk of these leaks and are eligible to receive gastric preconditioning by percutaneous angioembolization before an…
- Trial name
- NCT07449208
- Testing
- Esophagectomy
- Where
- 7 sites in United States
- Volunteers
- 40 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gynecologic Cancer, Anastomotic Leak
ECO-LEAK Technique: Early Detection of Colorectal Anastomotic Leakage by Transvaginal Ultrasound
The main hypothesis is that anastomotic leakage can be predicted peri- and postoperatively.To this end, the aim is to establish the accuracy of transvaginal ultrasound with transrectal enema (Ecoenema-TV) for the diagnosis of…
- Conditions
- Gynecologic Cancer, Anastomotic Leak, Cytoreductive Surgery
- Trial name
- NCT05942209
- Testing
- ECO-LEAK transvaginal ultrasound, ECO-LEAK with CT-Scan or rectoscopy, CT-Scan or rectoscopy
- Where
- Spain
- Volunteers
- 766 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Anastomotic Leak
Anastomotic Leakage After Anterior Resection for Rectal Cancer - Predictive Biomarkers and Rectal Blood Flow
The purpose of this study is to determine whether reduced rectal blood flow is associated with the extent of surgery when performing an operation to remove rectal cancer.
- Trial name
- NCT02401100
- Where
- Sweden
- Volunteers
- 36 people
- Sponsor
- Umeå University
Anastomotic Leak Esophagus
Anastomotic Leaks in Esophageal Squamous Cell Carcinoma Patients After Trimodal Therapy
To investigate the clinical factors and preoperative treatment to the future anastomotic location of cervical esophagus that were correlated with anastomotic leaks in esophageal squamous cell carcinoma patients undergoing…
- Trial name
- NCT06556355
- Testing
- neoadjuvant chemoradiation and McKeown esophagectomy
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Qiaoqiao Li
Gastrointestinal Cancer, Colorectal Cancer
Microbiome Analysis in esoPhageal, PancreatIc and Colorectal CaNcer Patients Undergoing Gastrointestinal Surgery
The MA-PPING is a multicenter prospective observational study that includes patients undergoing surgery for gastrointestinal cancer.
- Conditions
- Gastrointestinal Cancer, Colorectal Cancer, Pancreatic Cancer, Esophageal Cancer
- Trial name
- MA-PPING (NCT04189393)
- Volunteers
- 60 people
- Sponsor
- Radboud University Medical Center
Colorectal Surgery, Enhanced Recovery
CRP Point-of-care Testing Trajectory, a Predictive Factor for Anastomotic Leak in Elective Colorectal Surgery
In colorectal surgery, one of the most feared complications is anastomotic leak (AL). To limit the consequences of AL, it must be diagnosed as early as possible, before it becomes symptomatic.
- Conditions
- Colorectal Surgery, Enhanced Recovery, CRP Point-of-care Testing Trajectory, Post-operative Complication
- Trial name
- CRP (NCT07464600)
- Testing
- blood sample, Blood taken from a fingertip, Abdomino-pelvic CT scan
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Complication, Anastomotic Leak
Prediction of Abdominal Complications After GastroEnterological Surgery
The aim of this multi-centered study is to understand the epidemiology of infectious complications after gastrointestinal surgery in China.
- Conditions
- Complication, Anastomotic Leak, Gastrointestinal Cancer
- Trial name
- PACAGE (NCT03828266)
- Testing
- No intervention
- Where
- 19 sites in China
- Volunteers
- 4,000 people
- Sponsor
- Peking University
Anastomotic Leakage
Drainage Fluid Biomarkers and Anastomotic Leakage in Colorectal Surgery. A Monocentric Prospective Observational Study
Anastomotic leakage (AL) is one of the most feared intra-abdominal septic complications (IASC) after colorectal surgery. It is defined as the leak of intestinal content due to an anastomotic dehiscence.
- Trial name
- ALbiomarkers (NCT04846283)
- Testing
- Elective or emergency colorectal surgery for cancer, diverticular disease, inflammatory bowel-disease or reversal of Hartmann's procedure
- Where
- Italy
- Volunteers
- 207 people
- Sponsor
- University of Palermo
Ovarian Cancer
Identification of Risk Factors and Construction of Prediction Model for Postoperative Intestinal Anastomotic Leakage in Ovarian Cancer
This study was a multicenter, retrospective cohort study. Although advancements in surgical techniques have mitigated the incidence of intestinal anastomotic fistula, complete avoidance remains elusive.
- Trial name
- NCT06458361
- Testing
- Type of bowel resection, surgical complexity score, intraoperative blood loss, perioperative erythrocyte transfusion, type of anastomosis
- Where
- China
- Volunteers
- 401 people
- Sponsor
- Zhongda Hospital
Anastomotic Leak, Anastomotic Leak Large Intestine
Low Tie Versus High Tie of the Inferior Mesenteric Vein During Colorectal Cancer Surgery: A Randomized Clinical Trial
This study aim to determine if a different surgical technique could result in a lower anastomotic leak rate. The two techniques are equally used around the world and well described by the international literature but this is the…
- Conditions
- Anastomotic Leak, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum, Colon Cancer
- Trial name
- LOTHVEIN (NCT05411783)
- Testing
- Low tie of IMV
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- San Carlo di Nancy Hospital
Colorectal Surgery, Anastomotic Leak
Intracorporeal Vs Extracorporeal Anastomosis in Laparoscopic Right Hemicolectomy
Objective. The aim of this study was to evaluate short-term outcomes of performing intracorporeal versus extracorporeal anastomosis in laparoscopic right hemicolectomy for right colon neoplasm. Background.
- Conditions
- Colorectal Surgery, Anastomotic Leak, Colectomy, Laparoscopy
- Trial name
- IVEA (NCT03990714)
- Testing
- Right hemicolectomy
- Volunteers
- 168 people
- Sponsor
- Hospital Universitario Torrecárdenas
Intestinal Anastomosis Complication
Magnamosis First-in-human Study of Feasibility and Safety
Anastomosis of intestine or other viscera currently requires open or laparoscopic surgery and is often the most difficult, time-consuming, and expensive part of many operations.
- Trial name
- Magnamosis (NCT02043392)
- Testing
- Magnamosis
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Michael Harrison
Anastomotic Leak Esophagus, Swallowing Disorder
Functional Outcome After Anastomotic Leak After Oesophagectomies
The main surgical treatment for oesophageal cancer is a curative resection, mostly performed according to Ivor Lewis. However, despite careful work and refined surgical techniques, anastomotic leakage (AL) occurs in more than…
- Trial name
- FOAL (NCT05945654)
- Testing
- Anastomotic Leak after Ivor Lewis Oesophagectomy
- Where
- Switzerland
- Sponsor
- Stefan Gutknecht
Rectal Cancer
Application of Left Colic Artery Preservation, Anastomotic Reinforcing Sutures and Transanal Tube in Robotic Low Anterior Resection
The purpose of this study is to evaluate the results of combined application of left colic artery preservation, anastomotic reinforcing sutures and postoperative transanal tube placement in robotic Low Anterior Resection for…
- Trial name
- NCT03609710
- Testing
- Transanal tube placement, Left colic artery preservation, Anastomotic reinforcing sutures
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Fudan University