Clinical trials: Anastomotic Leak Rectum
Rectum Cancer, Stoma Colostomy
Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer
RATIONALE: Colorectal cancer is one of the most common cancers. However, approaches to minimize surgical trauma, preserve anal function, avoid abdominal stoma, and improve quality of life for patients with ultralow rectal cancers…
- Conditions
- Rectum Cancer, Stoma Colostomy, Faecal Incontinence, Leakage, Anastomotic
- Trial name
- NCT05245565
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai 10th People's Hospital
Anastomotic Leak Rectum
Investigation of the Benefit of Using an Autologous Platelet-rich Fibrin Matrix (Obsidian ASG®) for Treatment of Anastomosis During Rectal Surgery
Anastomotic insufficiency remains one of the most significant problems after rectal resection.The complications following anastomotic insufficiency leads to increased morbidity and mortality with subsequent prolongation of…
- Trial name
- ORSY (NCT05174910)
- Testing
- Obsidian ASG
- Where
- 13 sites in Austria, Germany and 3 more
- Volunteers
- 250 people
- Sponsor
- Vivostat
Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum
Human Intestinal Microbiome and Surgical Outcomes in Patients Undergoing Colorectal Cancer Surgery
Intro: Recent studies on colorectal cancer surgery have been focusing on the role of intestinal microbiome on surgical outcomes.
- Trial name
- Microbiota (NCT04005118)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anastomotic Leak Rectum
Routine Endoscopic Evaluation of Colorectal Anastomoses for Early Detection of Anastomotic Leakage
The objective of this international prospective observational study is to evaluate the implementation of a point-of-care digital rectoscope (LumenEye) into routine care to detect colorectal anastomotic leakage in the early…
- Trial name
- REAL (NCT06493565)
- Testing
- Routine endoscopic anastomosis inspection
- Where
- 5 sites in France, Italy and 3 more
- Volunteers
- 150 people
- Sponsor
- Amsterdam UMC, location VUmc
Rectal Cancer, Anastomotic Leak Rectum
Volume-outcome Relationship in Rectal Cancer Surgery
Hospital centralization effect is reported to lower complications and mortality especially for high risk and complex general surgery operations, including colorectal surgery.
- Trial name
- NCT04761536
- Testing
- Rectal cancer case centralization
- Volunteers
- 187 people
- Sponsor
- University of Rome Tor Vergata
Rectum Cancer, Anastomotic Leak
Betacyanin for Early Diagnosis and Recovery of Anastomotic Leakage After Rectal Cancer Surgery: A Single-Center, Prospective, Controlled Trial
This single-center, prospective, controlled trial compares betacyanin versus conventional methods for early diagnosis and healing assessment of anastomotic leakage after rectal cancer surgery.
- Trial name
- NCT07726966
- Testing
- Betacyanin, Pelvic Drainage Fluid Betacyanin Assay
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Southwest Hospital, China
Rectal Cancer Surgery, Anastomotic Leak Rectum
Impact of IMA Occlusion on Anastomotic Leakage
Rectal cancer is primarily treated with surgery, including low anterior resection or ultra-low anterior resection depending on tumor characteristics.
- Conditions
- Rectal Cancer Surgery, Anastomotic Leak Rectum, Inferior Mesenteric Artery
- Trial name
- NCT07656974
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Istanbul Saglik Bilimleri University
Cancer
Peritoneal Microdialysis in Patients Undergoing Low Anterior Resection for Rectum Cancer
Anastomotic leakage is a serious complication after LAR with high morbidity and mortality rates. Early diagnosis and treatment is mandatory.
- Trial name
- NCT01062334
- Testing
- Peritoneal Microdialysis, CT-scan, leakage scoring
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Anastomotic Leak Large Intestine, Anastomotic Leak Rectum
"Colorectal Leakage App" for Early Detection of Anastomotic Leakage After Colorectal Surgeries
The aim of this prospective observational study is to evaluate the effectiveness of the mobile application "Colorectal Leakage App" in the early diagnosis of anastomotic leakage after colorectal surgeries at the National Research…
- Trial name
- NCT06273826
- Testing
- "Colorectal Leakage App"
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- National Research Oncology and Transplantology Center, Kazakhstan
Rectal Cancer
SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak
The goal of this clinical trial is to learn whether using a reinforcing material called SIS (small intestinal submucosa) during bowel connection after rectal cancer surgery can help prevent anastomotic leakage-a serious…
- Trial name
- NCT07209787
- Testing
- SIS-reinforced anastomosis
- Where
- China
- Volunteers
- 966 people
- Sponsor
- Beijing Chao Yang Hospital
Anastomotic Leak Rectum
Evaluation of AL Prediction for Rectal Cancer
Anastomotic leakage is one of the most serious postoperative complications of low rectal cancer, with an incidence of 3%-21%. The occurrence of anastomotic leakage is related to many factors, and the occurrence of anastomotic…
- Trial name
- NCT05610904
- Testing
- Prediction model evaluation
- Where
- China
- Volunteers
- 418 people
- Sponsor
- Changhai Hospital