Clinical trials: Anastomotic Leakage
Azygos Vein Preservation Versus Disconnection, Tracheo-Esophageal Fistula With Atresia of Esophagus
Azygos Vein Preservation; Its Impact on Early Outcomes After Neonatal EA/TOF Repair
Azygos vein preservation revisited: impact on early outcomes after repair of Esophageal atresia/ Tracheo-Esophageal Fistula in newborns. A randomized controlled study.
- Conditions
- Azygos Vein Preservation Versus Disconnection, Tracheo-Esophageal Fistula With Atresia of Esophagus, Leak, Anastomotic, Stricture Esophagus
- Trial name
- EArAzygousvp (NCT05957562)
- Testing
- EA/TOF primary repair with Azygos vein preservation, EA/TOF primary repair with Azygos vein sacrifice (disconnection)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- dr. Muhammad Abdelhafez Mahmoud, MD
Gastroesophageal Junction Adenocarcinoma, Surgery
Gastric Microperfusion in Patients Undergoing Gastroesophageal Resections
Gastroesophageal resection because of gastroesophageal junction (GEJ) adenocarcinoma is a massive surgical intervention. Currently, gastroesophageal cancer surgery is performed with upper laparotomy followed by thoracotomy at the…
- Trial name
- NCT02077673
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
C-Reactive Protein, Anastomotic Leak
C-protein Reactive for the Detection of Anastomotic Leakage After Surgery for Digestive Cancer
The aim of this study is to investigate the diagnostic accuracy of the C Protein Reactive (CRP) for the detection of Anastomotic leakage after surgery for digestive cancer.
- Conditions
- C-Reactive Protein, Anastomotic Leak, Digestive System Neoplasm
- Trial name
- NCT04133324
- Testing
- C-reactive protein
- Where
- Morocco
- Volunteers
- 500 people
- Sponsor
- Moroccan Society of Surgery
Esophageal Neoplasms, Constriction
Endoscopic Evaluation After Esophagectomy
Gastric conduit ischemia or anastomotic breakdown after esophagectomy with cervical esophagogastrostomy often cause severe complications, such as leakage, necrotic organs, and strictures.
- Conditions
- Esophageal Neoplasms, Constriction, Anastomotic Leak, Ischemia
- Trial name
- NCT02703142
- Testing
- Patients after esophagectomy
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Nagasaki University
Postoperative Ileus, Anastomotic Leak
SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition
The main objective is to investigate the effects of perioperative nutrition on postoperative ileus and anastomotic leakage in patients undergoing colorectal surgery.
- Trial name
- SANICSII (NCT02175979)
- Testing
- enriched enteral nutrition, standard
- Where
- 5 sites in Denmark, Netherlands
- Volunteers
- 280 people
- Sponsor
- Misha D.P. Luyer
Anastomotic Leak, Platelet-Rich Fibrin
Leukocyte and and Platelet-rich Fibrin Plasma for the Prevention of Anastomotic Leakage in Colorectal Anastomosis
Anastomotic leak rate in colorectal surgery is estimated between 4 and 20 percent. Leukocyte and and platelet-rich fibrin plasma (L-PRF) is second generation platelet concentrate whose application in colorectal anastomosis in…
- Conditions
- Anastomotic Leak, Platelet-Rich Fibrin, Colorectal Surgery
- Trial name
- NCT05264467
- Testing
- Platelet rich fibrin on colorectal anastomosis
- Where
- Chile
- Volunteers
- 106 people
- Sponsor
- Universidad de Concepcion
Rectal Cancer, Surgery Indication
Low Powered Colorectal Anastomosis After Rectal Excision (OASIS)
The objectiive of this prospective, international cohort is to compare two anastomotic techniques (DS vs TTSS) by collecting data during the surgery, and postoperatively (morbidity and functional outcomes).
- Trial name
- OASIS (NCT07146334)
- Where
- 15 sites in Belgium, Canada and 4 more
- Volunteers
- 400 people
- Sponsor
- Bordeaux Colorectal Institute
Anastomotic Leak
Role of Procalcitonin, C-Reactive Protein, and WBC Count in Prediction of Colorectal Anastomotic Leak
The interest in identifying a biological marker for the early detection of AL is growing. Such a marker could play a vital role in modern fast-track multimodal protocols, allowing safe and early discharge of patients after…
- Trial name
- NCT05159024
- Testing
- CRP, PCT, and WBCs trajectories
- Where
- Egypt
- Volunteers
- 205 people
- Sponsor
- Suez Canal University
Rectal Cancer, Robotic
The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal Cancer
Anastomotic complications are serious complications after anus preserving surgery for rectal cancer,the instrument anastomosis technology are one of the factors that influence the occurrence of anastomotic complications after…
- Conditions
- Rectal Cancer, Robotic, Anastomotic Leak, Laparoscopic
- Trial name
- NCT05667181
- Testing
- Surform
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Nanchang University
Leakage, Anastomotic, Colon Cancer
COLOFLOW: Laser Speckle Contrast Imaging Versus Near-infrared Fluorescence Imaging With Indocyanine Green
COLOFLOW is a prospective observational study investigating whether Laser Speckle Contrast Imaging (LSCI), a dye-free and objective perfusion imaging technique, corresponds with the currently used subjective assessment of…
- Conditions
- Leakage, Anastomotic, Colon Cancer, Colon Anastomosis, Colon and Rectal Cancer
- Trial name
- COLOFLOW (NCT07720505)
- Testing
- Laser Speckle Contrast Imaging
- Volunteers
- 30 people
- Sponsor
- Leiden University Medical Center
Complication, Anastomotic Leak
Prediction of Intra-abdominal Infectious Complication by Drainage Fluid Analysis
In our previous study, a nomogram model was established to predict intra-abdominal infectious complications after gastrointestinal surgery.
- Conditions
- Complication, Anastomotic Leak, Intraabdominal Infections, Inflammatory Response
- Trial name
- APPEAL-GC (NCT03862378)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University
Pancreatic Cancer, Pancreaticoduodenal; Fistula
Early Detection of Anastomotic Leakage by Microdialysis Catheters
Anastomotic leakage of the pancreatojejunostomy is often discovered with considerable delay, causing severe peritonitis, hemorrhage due to erosion of vessels, sepsis, and death.
- Conditions
- Pancreatic Cancer, Pancreaticoduodenal; Fistula, Pancreas; Fistula, Pancreatic Fistula
- Trial name
- NCT03627559
- Testing
- Pancreaticoduodenectomy microdialysis catheter analyses
- Volunteers
- 35 people
- Sponsor
- Oslo University Hospital
Anastomotic Leak
The Impact of Indocyanine Green-enhanced Fluorescence Imaging on Bowel Transection in Left-sided Colorectal Resection
The aim of this study was to evaluate the impact of fluorescence imaging on the location of colorectal transection lines based on evaluation of perfusion with indocyanine green, how it's going to affect surgical planning and its…
- Trial name
- NCT02669485
- Testing
- indocyanine green, Fluorescence imaging
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
Colorectal Anastomosis Leak
Impact of Oxygen Saturation Levels on Anastomotic Leakage and Postoperative Complications in Colorectal Surgery
The aim of the present study was to evaluate the association between postoperative oxygen saturation levels and surgical complications, with particular emphasis on anastomotic leakage, in patients undergoing elective colorectal…
- Trial name
- NCT07534618
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people
- Sponsor
- Yasir Musa Kesgin
Rectal Cancer
Application of Left Colic Artery Preservation, Anastomotic Reinforcing Sutures and Transanal Tube in Robotic Low Anterior Resection
The purpose of this study is to evaluate the results of combined application of left colic artery preservation, anastomotic reinforcing sutures and postoperative transanal tube placement in robotic Low Anterior Resection for…
- Trial name
- NCT03609710
- Testing
- Transanal tube placement, Left colic artery preservation, Anastomotic reinforcing sutures
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Fudan University
Anastomotic Leak
Risk Factors Associated With Anastomotic Leak and Perioperative Mortality in Elderly
This is a retrospective cohort study of all consecutive patients who underwent colon or rectal resection, between the years 2012-2017 at Rabin Medical Center, a tertiary referral center in Israel.
- Trial name
- NCT04518384
- Testing
- colon or rectum resection
- Where
- Israel
- Volunteers
- 536 people
- Sponsor
- Rabin Medical Center
Rectal Cancer, Anastomotic Leakage
Somatostatin Plus Clear Liquid Diet Versus Diverting Stoma in Patients With Rectal Cancer Undergoing Ultra-Low Anterior Resection
The goal of this clinical trial is to learn if somatostatin plus a clear liquid diet can help prevent severe leakage after rectal cancer surgery in adults with low or mid rectal cancer who are scheduled to have ultra-low anterior…
- Trial name
- SC-Stoma (NCT07605611)
- Testing
- Somatostatin, Clear Liquid Diet, Prophylactic Diverting Stoma
- Where
- 3 sites in China
- Volunteers
- 72 people
- Sponsor
- Tongji Hospital
Genito Urinary Function Evaluation
Genito Urinary Function With High or Low Inferior Mesenteric Artery Ligation in Laparoscopic Anterior Rectal Resection
The aim of this study is to compare the incidence of genito-urinary function depression and anastomotic leak in Laparoscopic Anterior Rectal Resection (LAR) with Total Mesorectal Excision with Ligation if the Inferior Mesenteric…
- Trial name
- NCT02153801
- Testing
- During the surgical procedure of Laparoscopic Low Anterior Resection with Total mesorectal Excision .
- Where
- Italy
- Volunteers
- 212 people
- Sponsor
- Niguarda Hospital
Intestinal Volvulus, Colon, Sigmoid
Best Management of Sigmoid Volvulus: A Prospective Randomized Trial
The purpose of this study is to obtain a better understanding of the best management of left-sided colonic emergencies.
- Trial name
- NCT01682395
- Testing
- Resection and anastomosis, Resection and colostomy, Mesosigmoidopexy
- Where
- Malawi
- Volunteers
- 29 people
- Sponsor
- University of North Carolina, Chapel Hill
Colorectal Cancer, Colon Cancer
MIMICC Study in Patients With Colorectal Cancer
This multicenter prospective interventional study will evaluate stool and saliva microRNA expression and microbiome composition in patients with histologically confirmed colon or rectal cancer during key phases of the diagnostic…
- Conditions
- Colorectal Cancer, Colon Cancer, Rectal Cancers
- Trial name
- MIMICC (NCT07494201)
- Testing
- Prospective Biological Sample Collection and Longitudinal Molecular Profiling, Diet and Lifestyle Assessment
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia