Clinical trials: Anatomical Pathological Condition
Lumbar Disc Herniation, Radiculopathy Lumbar
Efficacy and Safety of Electroacupuncture on Lumbar Disc Herniation with Radiculopathy
Lumbar disc herniation with radiculopathy (LDHR) is the local displacement of the intervertebral disc and its contents beyond the edge of the normal intervertebral disc space, resulting in pain, weakness or numbness in the muscle…
- Trial name
- NCT06611332
- Testing
- Electroacupuncture
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Cholecystitis; Gallstone
Robotic Cholecystectomy Using the Chinese Micro Hand S Robot: A Controlled, Randomized, Prospective Clinical Study
A single-blinded, prospective randomized parallel controlled clinical trial was designed and conducted from December 2019 to November 2020.
- Trial name
- NCT04803487
- Testing
- robot-assisted cholecystectomy
- Where
- China
- Volunteers
- 82 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Androgenetic Alopecia
To Evaluate the Safety, Tolerability and Efficacy in Male and Female with AGA Treated with HMI-115 Over a 24-week Treatment Period
An Open Label Study, to Evaluate Safety, Tolerability, and Efficacy Study in Male and Female with Androgenetic Alopecia Treated with HMI-115 over a 24-Week Treatment Period.
- Trial name
- NCT05324293
- Testing
- HMI-115
- Where
- Australia
- Volunteers
- 16 people
- Sponsor
- Hope Medicine (Nanjing) Co., Ltd
Rhinosinusitis
Laser Assisted Treatment of Chronic Sinusitis With and Without Light Activated Agents
Chronic rhinosinusitis (CRS) is common disorder which affects up to 13% of the US population. CRS affects numerous Quality of Life (QOL) factors including smell, sleep and communication.
- Trial name
- NCT00948519
- Testing
- Laser + ICG, Laser only
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York Head & Neck Institute
Immobility Syndrome, Fall
Goal-directed Mobilization of Medical Inpatients
Immobilization in general internal medicine inpatients is a major contributor to morbidity and mortality. Goal-directed mobilization (GDM) may improve mobility.
- Conditions
- Immobility Syndrome, Fall, Delirium, Sarcopenia
- Trial name
- GoMob-in (NCT04760392)
- Testing
- Goal-directed mobilization
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Psoriasis, Plaque Type Psorisis
Evaluation of Safety and Efficacy of IRX4204 in Mild to Moderate Plaque Psoriasis
The goal of this clinical trial is to learn if IRX4204 works to treat plaque psoriasis in adults. It will also learn about the safety of IRX4204.
- Conditions
- Psoriasis, Plaque Type Psorisis, Plaque Psoriasis
- Trial name
- NCT06723171
- Testing
- IRX4204
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Io Therapeutics
Pancreatic Fistula, Pancreatic Neoplasms
Treatment of the Pancreatic Stump With Neoprene®-Based Glue After High-risk Pancreatoduodenectomy
The study evaluates the safety and efficacy of Neoprene-based glue in the management of pancreatic stump after pancreatoduodenectomy (PD) in patients at high risk for pancreatic fistula and early neoplastic recurrence, compared…
- Conditions
- Pancreatic Fistula, Pancreatic Neoplasms, Postoperative Complications
- Trial name
- NCT03738787
- Testing
- Pancreatic duct occlusion with Neoprene, Pancreato-Jejunal anastomosis
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Mild Cognitive Impairment (MCI), Opioid Use
Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment
Mild cognitive impairment (MCI) affects a substantial proportion of older adults undergoing major surgery and may alter pain processing, pain experience, and opioid use after surgery.
- Conditions
- Mild Cognitive Impairment (MCI), Opioid Use, Cognitive Dysfunction, Postoperative Pain
- Trial name
- NCT07885085
- Where
- United States
- Volunteers
- 552 people
- Sponsor
- Miklos Kertai
Chronic Graft Versus Host Disease
Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD)
Graft versus Host Disease (GVHD) is frequent after allogeneic stem cell transplantation (alloSCT). GVHD occurs following 2 patterns : acute GVHD (aGVHD) or chronic GVHD (cGVHD).
- Trial name
- TIL-GVHD (NCT06247150)
- Testing
- Additional blood sample, cGVHD target tissue biopsy
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Bordeaux
Lumbar Disc Herniation
Strengthening Exercise and Activities of Daily Living Instructions for Patients With Lumbar Disc Herniation
Lumbar disc herniation (LDH) is one of the most common causes of mechanical low back pain (LBP) associated with radiating leg pain.
- Trial name
- NCT05021718
- Testing
- Strengthening exercises, Pharmacological therapy, Hot compression
- Where
- Bangladesh
- Volunteers
- 70 people
- Sponsor
- Chittagong Medical College
Alopecia, Radiodermatitis
Exploratory Study of Norepinephrine to Prevent Alopecia in Head and Neck Cancer Patients Treated With Radiotherapy
The study will evaluate the safety of topical norepinephrine in head and neck cancer patients who are receiving treatment with intensity modulated radiotherapy (IMRT).
- Trial name
- NCT01367990
- Testing
- Norepinephrine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- ProCertus BioPharm, Inc
Anatomical Pathological Condition
Assessment of Tele-expertise for Second Medical Opinion on Pathological Diagnosis
The purpose of this study is to determine whether digitalizing pathological slides and let it accessible on a server for a second medical opinion (tele-expertise) would reduce the time to diagnosis.
- Trial name
- NCT02374697
- Testing
- During tele-expertise
- Where
- 11 sites in France
- Volunteers
- 470 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hernia, Abdominal
This Randomized Controlled Study Aims to Investigate the Effect of Botox Injection in Abdominal Wall Muscle Post Major Abdominal Surgery in Terms of Postoperative Pain, Incidence of Incisional Hernia.
Aim of the work This randomized controlled study aims to investigate the effect of botox injection in abdominal wall muscle post major abdominal surgery in terms of postoperative pain, incidence of incisional hernia Study design…
- Trial name
- NCT04422197
- Testing
- Botox, surgery without botox injection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Congenital Diaphragmatic Hernia
Delayed Cord Clamping for Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a congenital anomaly associated with a high risk of mortality and need for life-saving interventions such as extracorporeal membrane oxygenation (ECMO), nitric oxide, and vasopressor…
- Trial name
- DING (NCT03314233)
- Testing
- DING
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Philadelphia
Abdominal Wall Hernia
Physiologic Tension of the Abdominal Wall
Restoring the physiologic tension of the abdominal wall is a key concept in abdominal wall reconstruction. Yet little is known quantitatively about the normal tension of the abdominal wall.
- Trial name
- NCT05163184
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery
Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study
The goal of this study is to compare vaginal mesh surgery with abdominal robotic-assisted mesh surgery for the treatment of genital prolapse in women.
- Conditions
- Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Mesh Reinforcement, Vaginal Apex/Uterine Prolapse
- Trial name
- NCT07359755
- Testing
- Vaginal mesh surgery for apical prolapse, Robotic-assisted abdominal mesh surgery with Upsylon device (Boston Scientific - USA) for vaginal apical prolapse
- Where
- Brazil
- Volunteers
- 86 people
- Sponsor
- University of Sao Paulo General Hospital
Chronic Pain, Sexual Dysfunction
Study Comparing Total Extraperitoneal Patch "TEP" Versus Lichtenstein According Chronic Pain
The purpose of this study is to se if there is a difference regarding chronic pain and sexual dysfunction one and tree years after laparoscopic un fixated preperitoneal mesh versus gold standard open fixated on lay mesh in…
- Trial name
- TEP-LICH (NCT00803985)
- Testing
- Total Extraperitoneal repair (TEP), Lichtenstein
- Where
- Sweden
- Volunteers
- 416 people
- Sponsor
- Skane University Hospital
Sarcopenia, Frail Elderly Syndrome
Effects of COcoa Supplement in FRail Elderly Subjects (COFRE)
The study use a double blind, placebo-controlled design enrolling male and female subjects between 55-90 yo to evaluate the effect of daily consumption of a cocoa beverage on anthropometric, metabolic, oxidative stress, physical…
- Trial name
- COFRE (NCT03585868)
- Testing
- Flavonoids, No Flavonoids
- Volunteers
- 30 people
- Sponsor
- National Polytechnic Institute, Mexico
Hernia, Inguinal, Recurrence
Hernia Belt in Laparoscopic Inguinal Hernia Repair
In this study, the investigators aimed to investigate the effect of hernia belt on postoperative complications and quality of life for patients who underwent laparoscopic inguinal hernia repair.
- Conditions
- Hernia, Inguinal, Recurrence, Seroma Following Procedure, Pain, Postoperative
- Trial name
- NCT06061068
- Testing
- Hernia belt compression
- Where
- China
- Volunteers
- 678 people
- Sponsor
- Nanchong Central Hospital
Lumbar Disc Herniation
A Biomechanical Study of the Lumbar Intervertebral Disc by Lever Positioning Manipulation
Purpose of Study: The purpose of this clinical trial is the clinical efficacy of different trigger modes of lever positioning manipulation (LPM) for the treatment of lumbar disc herniation (LDH).
- Trial name
- NCT06872918
- Testing
- Lever positioning manipulation, Cluster of pseudo-manipulators, Mechanics and kinematics data acquisition of unilateral wrenching patterns in lever positioning manipulation
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University